Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations

Blood

Volumn 121, Issue 23, 2013, Pages 4749-4752

  Neumann, Martin ^a   Heesch, Sandra ^a   Schlee, Cornelia ^a   Schwartz, Stefan ^a   Gökbuget, Nicola ^b   Hoelzer, Dieter ^b   Konstandin, Nikola P ^c,d   Ksienzyk, Bianka ^c,d   Vosberg, Sebastian ^c,d   Graf, Alexander ^d   Krebs, Stefan ^d   Blum, Helmut ^d   Raff, Thorsten ^e   Brüggemann, Monika ^e   Hofmann, Wolf Karsten ^f   Hecht, Jochen ^a   Bohlander, Stefan K ^c,d,g   Greif, Philipp A ^c,d,h   Baldus, Claudia D ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^f UNIVERSITY OF HEIDELBERG   (Germany)

^g PHILIPPS UNIVERSITY MARBURG   (Germany)

^h GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BMI1 PROTEIN; DNA METHYLTRANSFERASE 3A; NOTCH1 RECEPTOR; POLYCOMB REPRESSIVE COMPLEX 2; CD135 ANTIGEN; DNA (CYTOSINE 5) METHYLTRANSFERASE; FLT3 PROTEIN, HUMAN; NOTCH1 PROTEIN, HUMAN; TUMOR MARKER;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; AGED; ARTICLE; DNM2 GENE; EARLY T CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA; EPIGENETICS; EXOME; FAT TUMOR SUPPRESSOR HOMOLOG 3 GENE; FAT1 GENE; FEMALE; GENE; GENE SEQUENCE; HUMAN; HUMAN TISSUE; INDEL MUTATION; MAJOR CLINICAL STUDY; MALE; MLL2 GENE; NEXT GENERATION SEQUENCING; PRE T LYMPHOCYTE; PRIORITY JOURNAL; SOMATIC MUTATION; ADOLESCENT; FOLLOW UP; GENETIC EPIGENESIS; GENETICS; HIGH THROUGHPUT SEQUENCING; MIDDLE AGED; MUTATION; PATHOLOGY; PROGNOSIS;

ADOLESCENT; ADULT; AGED; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; EPIGENESIS, GENETIC; EXOME; FEMALE; FMS-LIKE TYROSINE KINASE 3; FOLLOW-UP STUDIES; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MALE; MIDDLE AGED; MUTATION; PRECURSOR CELLS, T-LYMPHOID; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROGNOSIS; RECEPTOR, NOTCH1; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

MLCS; MLOWN;

EID: 84881041250     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-11-465138     Document Type: Article

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