Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner

Molecular and Cellular Biology

Volumn 23, Issue 8, 2003, Pages 2942-2952

  Nie, Zuqin ^a   Yan, Zhijiang ^a   Chen, Everett H ^b   Sechi, Salvatore ^a,d   Ling, Chen ^a   Zhou, Sharleen ^c   Xue, Yutong ^a   Yang, Dafeng ^a   Murray, Darryl ^a   Kanakubo, Emi ^a   Cleary, Michael L ^b   Wang, Weidong ^a,c  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; HYBRID PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN; ONCOPROTEIN; PROTEIN ENL; PROTEIN HOXA7; PROTEIN SWI; TRANSCRIPTION FACTOR SNF; UNCLASSIFIED DRUG;

ACUTE LEUKEMIA; ARTICLE; CHROMATIN; CHROMOSOME TRANSLOCATION; COMPLEX FORMATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOSOME; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; YEAST;

AMINO ACID SEQUENCE; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; CLONING, MOLECULAR; DNA-BINDING PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; MACROMOLECULAR SUBSTANCES; MOLECULAR SEQUENCE DATA; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN SUBUNITS; PROTO-ONCOGENES; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0037385212     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.8.2942-2952.2003     Document Type: Article

References (48)

1. Ayton, P. M., and M. L. Cleary. 2001. Transformation of myeloid progenitors by MLL fusion proteins requires HoxA7 and HoxA9 and their DNA binding partner Pbx2. Blood 98:800.
2. Ayton, P. M., and M. L. Cleary. 2001. Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins. Oncogene 20:5695-5707.
3. Bultman, S., T. Gebuhr, D. Yee, C. La Mantia, J. Nicholson, A. Gilliam, F. Randazzo, D. Metzger, P. Chambon, G. Crabtree, and T. Magnuson. 2000. A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes. Mol. Cell. 6:1287-1295.
4. Butler, L. H., R. Slany, X. Cui, M. L. Cleary, and D. Y. Mason. 1997. The HRX proto-oncogene product is widely expressed in human tissues and localizes to nuclear structures. Blood 89:3361-3370.
5. Cairns, B. R., N. L. Henry, and R. D. Kornberg. 1996. TFG/TAF30/ANC1, a component of the yeast SWI/SNF complex that is similar to the leukemogenic proteins ENL and AF-9. Mol. Cell. Biol. 16:3308-3316.
6. Caslini, C., A. S. Alarcon, J. L. Hess, R. Tanaka, K. G. Murti, and A. Biondi. 2000. The amino terminus targets the mixed lineage leukemia (MLL) protein to the nucleolus, nuclear matrix and mitotic chromosomal scaffolds. Leukemia 14:1898-1908.
7. Debernardi, S., A. Bassini, L. K. Jones, T. Chaplin, B. Linder, D. R. de Bruijn, E. Meese, and B. D. Young. 2002. The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex. Blood 99:275-281.
8. Hamiche, A., R. Sandaltzopoulos, D. A. Gdula, and C. Wu. 1999. ATP-dependent histone octamer sliding mediated by the chromatin remodeling complex NURF. Cell 97:833-842.
9. Hassan, A. H., K. E. Neely, M. Vignali, J. C. Reese, and J. L. Workman. 2001. Promoter targeting of chromatin-modifying complexes. Front. Biosci. 6:D1054-D1064.
10. Hurlstone, A. F., I. A. Olave, N. Barker, M. Van Noort, and H. Clevers. 2002. Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein. Biochem. J. 364:255-264.
11. Iida, S., M. Seto, K. Yamamoto, H. Komatsu, A. Tojo, S. Asano, N. Kamada, Y. Ariyoshi, T. Takahashi, and R. Ueda. 1993. MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13. Oncogene 8:3085-3092.
12. Kato, H., A. Tjernberg, W. Zhang, A. N. Krutchinsky, W. An, T. Takeuchi, Y. Ohtsuki, S. Sugano, B. T. Chait, and R. G. Roeder. 2001. SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones. J. Biol. Chem. 277:5498-5505.
13. Kawagoe, H., R. Kawagoe, and K. Sano. 2001. Targeted down-regulation of MLL-AF9 with antisense oligodeoxyribonucleotide reduces the expression of the HOXA7 and -A10 genes and induces apoptosis in a human leukemia cell line, THP-1. Leukemia 15:1743-1749.
14. Khavari, P. A., C. L. Peterson, J. W. Tamkun, D. B. Mendel, and G. R. Crabtree. 1993. BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature 366: 170-174.
15. Klochendler-Yeivin, A., L. Fiette, J. Barra, C. Muchardt, C. Babinet, and M. Yaniv. 2000. The murine SNF5/IN11 chromatin remodeling factor is essential for embryonic development and tumor suppression. EMBO Rep. 1:500-506.
16. Klochendler-Yeivin, A., C. Muchardt, and M. Yaniv. 2002. SWI/SNF chromatin remodeling and cancer. Curr. Opin. Genet. Dev. 12:73-79.
17. Krebs, J. E., and C. L. Peterson. 2000. Understanding "active" chromatin: a historical perspective of chromatin remodeling. Crit. Rev. Eukaryot. Gene Expr. 10:1-12.
18. Kwon, H., A. N. Imbalzano, P. A. Khavari, R. E. Kingston, and M. R. Green. 1994. Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex. Nature 370:477-481.
19. Laurent, B. C., M. A. Treitel, and M. Carlson. 1991. Functional interdependence of the yeast SNF2, SNF5, and SNF6 proteins in transcriptional activation. Proc. Natl. Acad. Sci. USA 88:2687-2691.
20. Lemon, B., C. Inouye, D. S. King, and R. Tjian. 2001. Selectivity of chromatin-remodelling cofactors for ligand-activated transcription. Nature 414:924-928.
21. Lorch, Y., B. R. Cairns, M. Zhang, and R. D. Kornberg. 1998. Activated RSC-nucleosome complex and persistently altered form of the nucleosome. Cell 94:29-34.
22. Muchardt, C., and M. Yaniv. 1993. A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor. EMBO J. 12:4279-4290.
23. Muller, C., and A. Leutz. 2001. Chromatin remodeling in development and differentiation. Curr. Opin. Genet. Dev. 11:167-174.
24. Nakamura, T., H. Alder, Y. Gu, R. Prasad, O. Canaani, N. Kamada, R. P. Gale, B. Lange, W. M. Crist, P. C. Nowell, et al. 1993. Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs. Proc. Natl. Acad. Sci. USA 90:4631-4635.
25. Nie, Z., Y. Xue, D. Yang, S. Zhou, B. J. Deroo, T. K. Archer, and W. Wang. 2000. A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex. Mol. Cell. Biol. 20:8879-8888.
26. Olave, I., W. Wang, Y. Xue, A. Kuo, and G. R. Crabtree. 2002. Identification of a polymorphic, neuron-specific chromatin remodeling complex. Genes Dev. 16:2509-2517.
27. Owen-Hughes, T., R. T. Utley, J. Cote, C. L. Peterson, and J. L. Workman. 1996. Persistent site-specific remodeling of a nucleosome array by transient action of the SWI/SNF complex. Science 273:513-516.
28. Phelan, M. L., S. Sif, G. J. Narlikar, and R. E. Kingston. 1999. Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits. Mol. Cell. 3:247-253.
29. Rubnitz, J. E., J. Morrissey, P. A. Savage, and M. L. Cleary. 1994. ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells. Blood 84:1747-1752.
30. Schnitzler, G., S. Sif, and R. E. Kingston. 1998. Human SWI/SNF interconverts a nucleosome between its base state and a stable remodeled state. Cell 94:17-27.
31. Schreiner, S. A., M. P. Garcia-Cuellar, G. H. Fey, and R. K. Slany. 1999. The leukemogenic fusion of MLL with ENL creates a novel transcriptional transactivator. Leukemia 13:1525-1533.
32. Sif, S., A. J. Saurin, A. N. Imbalzano, and R. E. Kingston. 2001. Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes. Genes Dev. 15:603-618.
33. Strahl, B. D., and C. D. Allis. 2000. The language of covalent histone modifications. Nature 403:41-45.
34. Tamkun, J. W., R. Deuring, M. P. Scott, M. Kissinger, A. M. Pattatucci, T. C. Kaufman, and J. A. Kennison. 1992. brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell 68:561-572.
35. Tkachuk, D. C., S. Kohler, and M. L. Cleary. 1992. Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell 71:691-700.
36. Toy, J., J. M. Yang, G. S. Leppert, and O. H. Sundin. 1998. The optx2 homeobox gene is expressed in early precursors of the eye and activates retina-specific genes. Proc. Natl. Acad. Sci. USA 95:10643-10648.
37. Versteege, I., N. Sevenet, J. Lange, M. F. Rousseau-Merck, P. Ambros, R. Handgretinger, A. Aurias, and O. Delattre. 1998. Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature 394:203-206.
38. Vignali, M., A. H. Hassan, K. E. Neely, and J. L. Workman. 2000. ATP-dependent chromatin-remodeling complexes. Mol. Cell. Biol. 20:1899-1910.
39. Wang, W., T. Chi, Y. Xue, S. Zhou, A. Kuo, and G. R. Crabtree. 1998. Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes. Proc. Natl. Acad. Sci. USA 95: 492-498.
40. Wang, W., J. Cote, Y. Xue, S. Zhou, P. A. Khavari, S. R. Biggar, C. Muchardt, G. V. Kalpana, S. P. Goff, M. Yaniv, J. L. Workman, and G. R. Crabtree. 1996. Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. EMBO J. 15:5370-5382.
41. Wang, W., Y. Xue, S. Zhou, A. Kuo, B. R. Cairns, and G. R. Crabtree. 1996. Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev. 10:2117-2130.
42. Weintraub, H., and M. Groudine. 1976. Chromosomal subunits in active genes have an altered conformation. Science 193:848-856.
43. Whitehouse, I., A. Flaus, B. R. Cairns, M. F. White, J. L. Workman, and T. Owen-Hughes. 1999. Nucleosome mobilization catalysed by the yeast SWI/ SNF complex. Nature 400:784-787.
44. Wong, A. K., F. Shanahan, Y. Chen, L. Lian, P. Ha, K. Hendricks, S. Ghaffari, D. Iliev, B. Penn, A. M. Woodland, R. Smith, G. Salada, A. Carillo, K. Laity, J. Gupte, B. Swedlund, S. V. Tavtigian, D. H. Teng, and E. Lees. 2000. BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res. 60:6171-6177.
45. Workman, J. L., and R. E. Kingston. 1998. Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu. Rev. Biochem. 67:545-579.
46. Xue, Y., J. C. Canman, C. S. Lee, Z. Nie, D. Yang, G. T. Moreno, M. K. Young, E. D. Salmon, and W. Wang. 2000. The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes. Proc. Natl. Acad. Sci. USA 97:13015-13020.
47. Yu, B. D., J. L. Hess, S. E. Horning, G. A. Brown, and S. J. Korsmeyer. 1995. Altered Hox expression and segmental identity in Mll-mutant mice. Nature 378:505-508.
48. Zhao, K., W. Wang, O. J. Rando, Y. Xue, K. Swiderek, A. Kuo, and G. R. Crabtree. 1998. Rapid and phosphoinositol-dependent binding of the SWI/ SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell 95:625-636.