-
3
-
-
57549090224
-
Treatment of childhood acute lymphoblastic leukemia
-
Stanulla M, Schrappe M. Treatment of childhood acute lymphoblastic leukemia. Semin Hematol 2009; 46: 52-63.
-
(2009)
Semin Hematol
, vol.46
, pp. 52-63
-
-
Stanulla, M.1
Schrappe, M.2
-
4
-
-
84863772728
-
Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: A report from the Children's Oncology Group
-
Hunger SP, Lu X, Devidas M, et al. Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the Children's Oncology Group. J Clin Oncol 2012; 30: 1663-69.
-
(2012)
J Clin Oncol
, vol.30
, pp. 1663-1669
-
-
Hunger, S.P.1
Lu, X.2
Devidas, M.3
-
5
-
-
79952095577
-
Modern therapy of acute lymphoblastic leukemia
-
Bassan R, Hoelzer D. Modern therapy of acute lymphoblastic leukemia. J Clin Oncol 2011; 29: 532-43.
-
(2011)
J Clin Oncol
, vol.29
, pp. 532-543
-
-
Bassan, R.1
Hoelzer, D.2
-
6
-
-
67649410242
-
Treating childhood acute lymphoblastic leukemia without cranial irradiation
-
Pui CH, Campana D, Pei D, et al. Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med 2009; 360: 2730-41.
-
(2009)
N Engl J Med
, vol.360
, pp. 2730-2741
-
-
Pui, C.H.1
Campana, D.2
Pei, D.3
-
7
-
-
34447519040
-
A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): An observational study and a multicentre randomised trial
-
Pieters R, Schrappe M, De Lorenzo P, et al. A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial. Lancet 2007; 370: 240-50.
-
(2007)
Lancet
, vol.370
, pp. 240-250
-
-
Pieters, R.1
Schrappe, M.2
De Lorenzo, P.3
-
8
-
-
0141634051
-
Origins of chromosome translocations in childhood leukaemia
-
Greaves MF, Wiemels J. Origins of chromosome translocations in childhood leukaemia. Nat Rev Cancer 2003; 3: 639-49.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 639-649
-
-
Greaves, M.F.1
Wiemels, J.2
-
10
-
-
33644545382
-
Infection, immune responses and the aetiology of childhood leukaemia
-
Greaves M. Infection, immune responses and the aetiology of childhood leukaemia. Nat Rev Cancer 2006; 6: 193-203.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 193-203
-
-
Greaves, M.1
-
12
-
-
0031026450
-
Aetiology of acute leukaemia
-
Greaves MF. Aetiology of acute leukaemia. Lancet 1997; 349: 344-49.
-
(1997)
Lancet
, vol.349
, pp. 344-349
-
-
Greaves, M.F.1
-
13
-
-
0027972308
-
Cancer incidence in atomic bomb survivors. Part III: Leukemia lymphoma and multiple myeloma 1950-1987
-
Preston DL, Kusumi S, Tomonaga M, et al. Cancer incidence in atomic bomb survivors. Part III: leukemia, lymphoma and multiple myeloma, 1950-1987. Radiat Res 1994; 137 (suppl): S68-S97.
-
(1994)
Radiat Res
, vol.137
, Issue.SUPPL.
-
-
Preston, D.L.1
Kusumi, S.2
Tomonaga, M.3
-
14
-
-
0031046866
-
Risk of childhood cancer from fetal irradiation
-
Doll R, Wakeford R. Risk of childhood cancer from fetal irradiation. Br J Radiol 1997; 70: 130-39.
-
(1997)
Br J Radiol
, vol.70
, pp. 130-139
-
-
Doll, R.1
Wakeford, R.2
-
15
-
-
79960244818
-
Numbers and proportions of leukemias in young people and adults induced by radiation of natural origin
-
Kendall G, Little MP, Wakeford R. Numbers and proportions of leukemias in young people and adults induced by radiation of natural origin. Leuk Res 2011; 35: 1039-43.
-
(2011)
Leuk Res
, vol.35
, pp. 1039-1043
-
-
Kendall, G.1
Little, M.P.2
Wakeford, R.3
-
16
-
-
84858738434
-
Exposure to extremely low-frequency magnetic fields and the risk of childhood cancer: Update of the epidemiological evidence
-
Schüz J. Exposure to extremely low-frequency magnetic fields and the risk of childhood cancer: update of the epidemiological evidence. Progr Biophysics Mol Biol 2011; 107: 339-42.
-
(2011)
Progr Biophysics Mol Biol
, vol.107
, pp. 339-342
-
-
Schüz, J.1
-
17
-
-
0003081059
-
The infective theory of acute leukaemia
-
Ward G. The infective theory of acute leukaemia. Br J Child Dis 1917; 14: 10-20.
-
(1917)
Br J Child Dis
, vol.14
, pp. 10-20
-
-
Ward, G.1
-
18
-
-
0024204062
-
Evidence for an infective cause of childhood leukaemia: Comparison of a Scottish New Town with nuclear reprocessing sites in Britain
-
Kinlen L. Evidence for an infective cause of childhood leukaemia: comparison of a Scottish New Town with nuclear reprocessing sites in Britain. Lancet 1988; 332: 1323-27.
-
(1988)
Lancet
, vol.332
, pp. 1323-1327
-
-
Kinlen, L.1
-
19
-
-
0028878555
-
Epidemiological evidence for an infective basis in childhood leukaemia
-
Kinlen LJ. Epidemiological evidence for an infective basis in childhood leukaemia. Br J Cancer 1995; 71: 1-5.
-
(1995)
Br J Cancer
, vol.71
, pp. 1-5
-
-
Kinlen, L.J.1
-
20
-
-
0025347171
-
Immunisation and herd immunity
-
Anderson RM, May RM. Immunisation and herd immunity. Lancet 1990; 335: 641-45.
-
(1990)
Lancet
, vol.335
, pp. 641-645
-
-
Anderson, R.M.1
May, R.M.2
-
22
-
-
0023857908
-
Speculations on the cause of childhood acute lymphoblastic leukemia
-
Greaves MF. Speculations on the cause of childhood acute lymphoblastic leukemia. Leukemia 1988; 2: 120-25.
-
(1988)
Leukemia
, vol.2
, pp. 120-125
-
-
Greaves, M.F.1
-
23
-
-
20444451978
-
Day care in infancy and risk of childhood acute lymphoblastic leukaemia: Findings from a UK case-control study
-
Gilham C, Peto J, Simpson J, et al. Day care in infancy and risk of childhood acute lymphoblastic leukaemia: findings from a UK case-control study. BMJ 2005; 330: 1294-97.
-
(2005)
BMJ
, vol.330
, pp. 1294-1297
-
-
Gilham, C.1
Peto, J.2
Simpson, J.3
-
24
-
-
77953738079
-
A meta-analysis of the association between day-care attendance and childhood acute lymphoblastic leukaemia
-
Urayama KY, Buffler PA, Gallagher ER, Ayoob JM, Ma X. A meta-analysis of the association between day-care attendance and childhood acute lymphoblastic leukaemia. Int J Epidemiol 2010; 39: 718-32.
-
(2010)
Int J Epidemiol
, vol.39
, pp. 718-732
-
-
Urayama, K.Y.1
Buffler, P.A.2
Gallagher, E.R.3
Ayoob, J.M.4
Ma, X.5
-
25
-
-
3342888083
-
Population mixing and childhood leukaemia: Fallon and other US clusters
-
Kinlen L, Doll R. Population mixing and childhood leukaemia: Fallon and other US clusters. Br J Cancer 2004; 91: 1-3.
-
(2004)
Br J Cancer
, vol.91
, pp. 1-3
-
-
Kinlen, L.1
Doll, R.2
-
26
-
-
33644935230
-
Childhood leukemia incidence in Britain, 1974-2000: Time trends and possible relation to influenza epidemics
-
Kroll ME, Draper GJ, Stiller CA, Murphy MFG. Childhood leukemia incidence in Britain, 1974-2000: time trends and possible relation to influenza epidemics. J Natl Cancer Inst 2006; 98: 417-20.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 417-420
-
-
Kroll, M.E.1
Draper, G.J.2
Stiller, C.A.3
Murphy, M.F.G.4
-
27
-
-
65249178875
-
The TEL-AML1 leukemia fusion gene dysregulates the TGFb pathway in early B lineage progenitor cells
-
Ford AM, Palmi C, Bueno C, et al. The TEL-AML1 leukemia fusion gene dysregulates the TGFb pathway in early B lineage progenitor cells. J Clin Invest 2009; 119: 826-36.
-
(2009)
J Clin Invest
, vol.119
, pp. 826-836
-
-
Ford, A.M.1
Palmi, C.2
Bueno, C.3
-
28
-
-
0002734880
-
The hereditary basis of human leukemia
-
Henderson ES, Lister TA, Greaves MF, eds, Philadelphia: WB Saunders
-
Taylor GM, Birch JM. The hereditary basis of human leukemia. In: Henderson ES, Lister TA, Greaves MF, eds. Leukemia. 6th edn. Philadelphia: WB Saunders, 1996: 210-45.
-
(1996)
Leukemia. 6th Edn
, pp. 210-245
-
-
Taylor, G.M.1
Birch, J.M.2
-
29
-
-
0342905433
-
Risks of leukaemia and solid tumours in individuals with Down's syndrome
-
Hasle H, Clemmensen IH, Mikkelsen M. Risks of leukaemia and solid tumours in individuals with Down's syndrome. Lancet 2000; 355: 165-69.
-
(2000)
Lancet
, vol.355
, pp. 165-169
-
-
Hasle, H.1
Clemmensen, I.H.2
Mikkelsen, M.3
-
30
-
-
77956089407
-
Candidate gene association studies and risk of childhood acute lymphoblastic leukemia: A systematic review and meta-analysis
-
Vijayakrishnan J, Houlston RS. Candidate gene association studies and risk of childhood acute lymphoblastic leukemia: a systematic review and meta-analysis. Haematologica 2010; 95: 1405-14.
-
(2010)
Haematologica
, vol.95
, pp. 1405-1414
-
-
Vijayakrishnan, J.1
Houlston, R.S.2
-
31
-
-
69349101565
-
Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia
-
Papaemmanuil E, Hosking FJ, Vijayakrishnan J, et al. Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. Nat Genet 2009; 41: 1006-10.
-
(2009)
Nat Genet
, vol.41
, pp. 1006-1010
-
-
Papaemmanuil, E.1
Hosking, F.J.2
Vijayakrishnan, J.3
-
32
-
-
69349091330
-
Germline genomic variants associated with childhood acute lymphoblastic leukemia
-
Trevino LR, Yang W, French D, et al. Germline genomic variants associated with childhood acute lymphoblastic leukemia. Nat Genet 2009; 41: 1001-05.
-
(2009)
Nat Genet
, vol.41
, pp. 1001-1005
-
-
Trevino, L.R.1
Yang, W.2
French, D.3
-
33
-
-
77952884769
-
Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk
-
Sherborne AL, Hosking FJ, Prasad RB, et al. Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk. Nat Genet 2010; 42: 492-94.
-
(2010)
Nat Genet
, vol.42
, pp. 492-494
-
-
Sherborne, A.L.1
Hosking, F.J.2
Prasad, R.B.3
-
34
-
-
77950955951
-
ARID5B SNP rs10821936 is associated with risk of childhood acute lymphoblastic leukemia in blacks and contributes to racial differences in leukemia incidence
-
Yang W, Trevino LR, Yang JJ, et al. ARID5B SNP rs10821936 is associated with risk of childhood acute lymphoblastic leukemia in blacks and contributes to racial differences in leukemia incidence. Leukemia 2010; 24: 894-96.
-
(2010)
Leukemia
, vol.24
, pp. 894-896
-
-
Yang, W.1
Trevino, L.R.2
Yang, J.J.3
-
35
-
-
59249100224
-
Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia
-
Yang JJ, Cheng C, Yang W, et al. Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. JAMA 2009; 301: 393-403.
-
(2009)
JAMA
, vol.301
, pp. 393-403
-
-
Yang, J.J.1
Cheng, C.2
Yang, W.3
-
36
-
-
58149095544
-
Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia
-
Harrison CJ. Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia. Br J Haematol 2009; 144: 147-56.
-
(2009)
Br J Haematol
, vol.144
, pp. 147-156
-
-
Harrison, C.J.1
-
37
-
-
34147224008
-
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
-
Mullighan CG, Goorha S, Radtke I, et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature 2007; 446: 758-64.
-
(2007)
Nature
, vol.446
, pp. 758-764
-
-
Mullighan, C.G.1
Goorha, S.2
Radtke, I.3
-
38
-
-
43049139905
-
BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
-
Mullighan CG, Miller CB, Radtke I, et al. BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature 2008; 453: 110-14.
-
(2008)
Nature
, vol.453
, pp. 110-114
-
-
Mullighan, C.G.1
Miller, C.B.2
Radtke, I.3
-
39
-
-
67249146555
-
JAK mutations in high-risk childhood acute lymphoblastic leukemia
-
Mullighan CG, Zhang J, Harvey RC, et al. JAK mutations in high-risk childhood acute lymphoblastic leukemia. Proc Natl Acad Sci USA 2009; 106: 9414-18.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9414-9418
-
-
Mullighan, C.G.1
Zhang, J.2
Harvey, R.C.3
-
40
-
-
70350519430
-
Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia
-
Russell LJ, Capasso M, Vater I, et al. Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood 2009; 114: 2688-98.
-
(2009)
Blood
, vol.114
, pp. 2688-2698
-
-
Russell, L.J.1
Capasso, M.2
Vater, I.3
-
41
-
-
70350680415
-
Rearrangement of CRLF2 in B-progenitor-and Down syndrome-associated acute lymphoblastic leukemia
-
Mullighan CG, Collins-Underwood JR, Phillips LA, et al. Rearrangement of CRLF2 in B-progenitor-and Down syndrome-associated acute lymphoblastic leukemia. Nat Genet 2009; 41: 1243-46.
-
(2009)
Nat Genet
, vol.41
, pp. 1243-1246
-
-
Mullighan, C.G.1
Collins-Underwood, J.R.2
Phillips, L.A.3
-
42
-
-
79952381408
-
CREBBP mutations in relapsed acute lymphoblastic leukaemia
-
Mullighan CG, Zhang J, Kasper LH, et al. CREBBP mutations in relapsed acute lymphoblastic leukaemia. Nature 2011; 471: 235-39.
-
(2011)
Nature
, vol.471
, pp. 235-239
-
-
Mullighan, C.G.1
Zhang, J.2
Kasper, L.H.3
-
43
-
-
34249733805
-
High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression
-
Kuiper RP, Schoenmakers EF, van Reijmersdal SV, et al. High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression. Leukemia 2007; 21: 1258-66.
-
(2007)
Leukemia
, vol.21
, pp. 1258-1266
-
-
Kuiper, R.P.1
Schoenmakers, E.F.2
Van Reijmersdal, S.V.3
-
44
-
-
38349177862
-
Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray
-
Kawamata N, Ogawa S, Zimmermann M, et al. Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray. Blood 2008; 111: 776-84.
-
(2008)
Blood
, vol.111
, pp. 776-784
-
-
Kawamata, N.1
Ogawa, S.2
Zimmermann, M.3
-
45
-
-
34249668665
-
Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization
-
Strefford JC, Worley H, Barber K, et al. Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization. Oncogene 2007; 26: 4306-18.
-
(2007)
Oncogene
, vol.26
, pp. 4306-4318
-
-
Strefford, J.C.1
Worley, H.2
Barber, K.3
-
46
-
-
42349111493
-
Cooperative genetic defects in TLX3 rearranged pediatric T-ALL
-
Van Vlierberghe P, Homminga I, Zuurbier L, et al. Cooperative genetic defects in TLX3 rearranged pediatric T-ALL. Leukemia 2008; 22: 762-70.
-
(2008)
Leukemia
, vol.22
, pp. 762-770
-
-
Van Vlierberghe, P.1
Homminga, I.2
Zuurbier, L.3
-
47
-
-
33745198270
-
A new recurrent 9q34 duplication in pediatric T-cell acute lymphoblastic leukemia
-
Van Vlierberghe P, Meijerink JP, Lee C, et al. A new recurrent 9q34 duplication in pediatric T-cell acute lymphoblastic leukemia. Leukemia 2006; 20: 1245-53.
-
(2006)
Leukemia
, vol.20
, pp. 1245-1253
-
-
Van Vlierberghe, P.1
Meijerink, J.P.2
Lee, C.3
-
48
-
-
67651144270
-
Pax5 haploinsufficiency cooperates with BCR-ABL1 to induce acute lymphoblastic leukemia
-
Miller C, Mullighan CG, Su X, et al. Pax5 haploinsufficiency cooperates with BCR-ABL1 to induce acute lymphoblastic leukemia. Blood 2008; 112: 293s.
-
(2008)
Blood
, vol.112
-
-
Miller, C.1
Mullighan, C.G.2
Su, X.3
-
49
-
-
77954609243
-
Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia
-
Virely C, Moulin S, Cobaleda C, et al. Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia. Leukemia 2010; 24: 1200-04.
-
(2010)
Leukemia
, vol.24
, pp. 1200-1204
-
-
Virely, C.1
Moulin, S.2
Cobaleda, C.3
-
50
-
-
70349242044
-
Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: On behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP)
-
Iacobucci I, Storlazzi C T, Cilloni D, et al. Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP). Blood 2009; 114: 2159-67.
-
(2009)
Blood
, vol.114
, pp. 2159-2167
-
-
Iacobucci, I.1
Storlazzi, C.T.2
Cilloni, D.3
-
51
-
-
58749109707
-
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia
-
Mullighan CG, Su X, Zhang J, et al. Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med 2009; 360: 470-80.
-
(2009)
N Engl J Med
, vol.360
, pp. 470-480
-
-
Mullighan, C.G.1
Su, X.2
Zhang, J.3
-
52
-
-
58749097408
-
A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: A genome-wide classification study
-
Den Boer ML, van Slegtenhorst M, De Menezes RX, et al. A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study. Lancet Oncol 2009; 10: 125-34.
-
(2009)
Lancet Oncol
, vol.10
, pp. 125-134
-
-
Den Boer, M.L.1
Van Slegtenhorst, M.2
De Menezes, R.X.3
-
53
-
-
76249096219
-
Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia
-
Yoda A, Yoda Y, Chiaretti S, et al. Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia. Proc Natl Acad Sci USA 2010; 107: 252-57.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 252-257
-
-
Yoda, A.1
Yoda, Y.2
Chiaretti, S.3
-
54
-
-
77649214639
-
Down syndrome acute lymphoblastic leukemia: A highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: A report from the iBFM Study Group
-
Hertzberg L, Vendramini E, Ganmore I, et al. Down syndrome acute lymphoblastic leukemia: a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the iBFM Study Group. Blood 2010; 115: 1006-17.
-
(2010)
Blood
, vol.115
, pp. 1006-1017
-
-
Hertzberg, L.1
Vendramini, E.2
Ganmore, I.3
-
55
-
-
77954516863
-
Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia
-
Harvey RC, Mullighan CG, Chen IM, et al. Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia. Blood 2010; 115: 5312-21.
-
(2010)
Blood
, vol.115
, pp. 5312-5321
-
-
Harvey, R.C.1
Mullighan, C.G.2
Chen, I.M.3
-
56
-
-
55249095625
-
Myeloproliferative disorders
-
Levine RL, Gilliland DG. Myeloproliferative disorders. Blood 2008; 112: 2190-98.
-
(2008)
Blood
, vol.112
, pp. 2190-2198
-
-
Levine, R.L.1
Gilliland, D.G.2
-
57
-
-
84867403265
-
Outcome in children with Down's syndrome and acute lymphoblastic leukemia: Role of IKZF1 deletions and CRLF2 aberrations
-
Buitenkamp TD, Pieters R, Gallimore NE, et al. Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations. Leukemia 2012; 26: 2204-11.
-
(2012)
Leukemia
, vol.26
, pp. 2204-2211
-
-
Buitenkamp, T.D.1
Pieters, R.2
Gallimore, N.E.3
-
58
-
-
84865118132
-
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia
-
Roberts KG, Morin RD, Zhang J, et al. Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. Cancer Cell 2012; 22: 153-66.
-
(2012)
Cancer Cell
, vol.22
, pp. 153-166
-
-
Roberts, K.G.1
Morin, R.D.2
Zhang, J.3
-
59
-
-
77952305440
-
Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: Results from the UK Medical Research Council ALL97/99 randomised trial
-
Moorman AV, Ensor HM, Richards SM, et al. Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial. Lancet Oncol 2010; 11: 429-38.
-
(2010)
Lancet Oncol
, vol.11
, pp. 429-438
-
-
Moorman, A.V.1
Ensor, H.M.2
Richards, S.M.3
-
60
-
-
0037348975
-
Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: A study of 20 cases
-
Harewood L, Robinson H, Harris R, et al. Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: a study of 20 cases. Leukemia 2003; 17: 547-53.
-
(2003)
Leukemia
, vol.17
, pp. 547-553
-
-
Harewood, L.1
Robinson, H.2
Harris, R.3
-
61
-
-
33947131584
-
Intrachromosomal amplification of chromosome 21 (iAMP21) may arise from a breakage-fusion-bridge cycle
-
Robinson HM, Harrison CJ, Moorman AV, Chudoba I, Strefford JC. Intrachromosomal amplification of chromosome 21 (iAMP21) may arise from a breakage-fusion-bridge cycle. Genes Chromosomes Cancer 2007; 46: 318-26.
-
(2007)
Genes Chromosomes Cancer
, vol.46
, pp. 318-326
-
-
Robinson, H.M.1
Harrison, C.J.2
Moorman, A.V.3
Chudoba, I.4
Strefford, J.C.5
-
62
-
-
46449085873
-
Minimal residual disease values discriminate between low and high relapse risk in children with B-cell precursor acute lymphoblastic leukemia and an intrachromosomal amplification of chromosome 21: The Austrian and German acute lymphoblastic leukemia Berlin-Frankfurt-Munster (ALL-BFM) trials
-
Attarbaschi A, Mann G, Panzer-Grumayer R, et al. Minimal residual disease values discriminate between low and high relapse risk in children with B-cell precursor acute lymphoblastic leukemia and an intrachromosomal amplification of chromosome 21: the Austrian and German acute lymphoblastic leukemia Berlin-Frankfurt-Munster (ALL-BFM) trials. J Clin Oncol 2008; 26: 3046-50.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3046-3050
-
-
Attarbaschi, A.1
Mann, G.2
Panzer-Grumayer, R.3
-
63
-
-
0027259413
-
Cytogenetically different leukemic clones at relapse of childhood acute lymphoblastic leukemia
-
Raimondi SC, Pui CH, Head DR, Rivera GK, Behm FG. Cytogenetically different leukemic clones at relapse of childhood acute lymphoblastic leukemia. Blood 1993; 82: 576-80.
-
(1993)
Blood
, vol.82
, pp. 576-580
-
-
Raimondi, S.C.1
Pui, C.H.2
Head, D.R.3
Rivera, G.K.4
Behm, F.G.5
-
64
-
-
57149118627
-
Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia
-
Mullighan CG, Phillips LA, Su X, et al. Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. Science 2008; 322: 1377-80.
-
(2008)
Science
, vol.322
, pp. 1377-1380
-
-
Mullighan, C.G.1
Phillips, L.A.2
Su, X.3
-
65
-
-
61549114444
-
Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia
-
Yang JJ, Bhojwani D, Yang W, et al. Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia. Blood 2008; 112: 4178-83.
-
(2008)
Blood
, vol.112
, pp. 4178-4183
-
-
Yang, J.J.1
Bhojwani, D.2
Yang, W.3
-
66
-
-
67649442524
-
Molecular allelokaryotyping of relapsed pediatric acute lymphoblastic leukemia
-
Kawamata N, Ogawa S, Seeger K, et al. Molecular allelokaryotyping of relapsed pediatric acute lymphoblastic leukemia. Int J Oncol 2009; 34: 1603-12.
-
(2009)
Int J Oncol
, vol.34
, pp. 1603-1612
-
-
Kawamata, N.1
Ogawa, S.2
Seeger, K.3
-
67
-
-
80051828388
-
Mutations and deletions of the TP53 gene predict nonresponse to treatment and poor outcome in first relapse of childhood acute lymphoblastic leukemia
-
Hof J, Krentz S, van Schewick C, et al. Mutations and deletions of the TP53 gene predict nonresponse to treatment and poor outcome in first relapse of childhood acute lymphoblastic leukemia. J Clin Oncol 2011; 29: 3185-93.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3185-3193
-
-
Hof, J.1
Krentz, S.2
Van Schewick, C.3
-
68
-
-
84864865832
-
CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia
-
Inthal A, Zeitlhofer P, Zeginigg M, et al. CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia. Leukemia 2012; 26: 1797-803.
-
(2012)
Leukemia
, vol.26
, pp. 1797-1803
-
-
Inthal, A.1
Zeitlhofer, P.2
Zeginigg, M.3
-
69
-
-
80052922387
-
Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: A report from the Children's Oncology Group
-
Zhang J, Mullighan CG, Harvey RC, et al. Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood 2011; 118: 3080-87.
-
(2011)
Blood
, vol.118
, pp. 3080-3087
-
-
Zhang, J.1
Mullighan, C.G.2
Harvey, R.C.3
-
71
-
-
58749095816
-
Early T-cell precursor leukaemia: A subtype of very high-risk acute lymphoblastic leukaemia
-
Coustan-Smith E, Mullighan CG, Onciu M, et al. Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. Lancet Oncol 2009; 10: 147-56.
-
(2009)
Lancet Oncol
, vol.10
, pp. 147-156
-
-
Coustan-Smith, E.1
Mullighan, C.G.2
Onciu, M.3
-
72
-
-
84862907593
-
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
-
Zhang J, Ding L, Holmfeldt L, et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 2012; 481: 157-63.
-
(2012)
Nature
, vol.481
, pp. 157-163
-
-
Zhang, J.1
Ding, L.2
Holmfeldt, L.3
-
73
-
-
77950299929
-
PHF6 mutations in T-cell acute lymphoblastic leukemia
-
Van Vlierberghe P, Palomero T, Khiabanian H, et al. PHF6 mutations in T-cell acute lymphoblastic leukemia. Nat Genet 2010; 42: 338-42.
-
(2010)
Nat Genet
, vol.42
, pp. 338-342
-
-
Van Vlierberghe, P.1
Palomero, T.2
Khiabanian, H.3
-
74
-
-
79952188025
-
Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia
-
Yang JJ, Cheng C, Devidas M, et al. Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia. Nat Genet 2011; 43: 237-41.
-
(2011)
Nat Genet
, vol.43
, pp. 237-241
-
-
Yang, J.J.1
Cheng, C.2
Devidas, M.3
-
75
-
-
84863162896
-
ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia
-
Xu H, Cheng C, Devidas M, et al. ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia. J Clin Oncol 2012; 30: 751-57.
-
(2012)
J Clin Oncol
, vol.30
, pp. 751-757
-
-
Xu, H.1
Cheng, C.2
Devidas, M.3
-
76
-
-
79960022324
-
Optimal therapy for acute lymphoblastic leukemia in adolescents and young adults
-
Schafer ES, Hunger SP. Optimal therapy for acute lymphoblastic leukemia in adolescents and young adults. Nat Rev Clin Oncol 2011; 8: 417-24.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 417-424
-
-
Schafer, E.S.1
Hunger, S.P.2
-
77
-
-
0037362950
-
Should adolescents with acute lymphoblastic leukemia be treated as old children or young adults? Comparison of the French FRALLE-93 and LALA-94 trials
-
Boissel N, Auclerc MF, Lheritier V, et al. Should adolescents with acute lymphoblastic leukemia be treated as old children or young adults? Comparison of the French FRALLE-93 and LALA-94 trials. J Clin Oncol 2003; 21: 774-80.
-
(2003)
J Clin Oncol
, vol.21
, pp. 774-780
-
-
Boissel, N.1
Auclerc, M.F.2
Lheritier, V.3
-
78
-
-
11144266589
-
Significant difference in outcome for adolescents with acute lymphoblastic leukemia treated on pediatric vs adult protocols in the Netherlands
-
De Bont JM, Holt B, Dekker AW, van der Does-van den Berg A, Sonneveld P, Pieters R. Significant difference in outcome for adolescents with acute lymphoblastic leukemia treated on pediatric vs adult protocols in the Netherlands. Leukemia 2004; 18: 2032-35.
-
(2004)
Leukemia
, vol.18
, pp. 2032-2035
-
-
De Bont, J.M.1
Holt, B.2
Dekker, A.W.3
Van Der Does-Van Den Berg, A.4
Sonneveld, P.5
Pieters, R.6
-
79
-
-
47849108085
-
What determines the outcomes for adolescents and young adults with acute lymphoblastic leukemia treated on cooperative group protocols? A comparison of Children's Cancer Group and Cancer and Leukemia Group B studies
-
Stock W, La M, Sanford B, et al. What determines the outcomes for adolescents and young adults with acute lymphoblastic leukemia treated on cooperative group protocols? A comparison of Children's Cancer Group and Cancer and Leukemia Group B studies. Blood 2008; 112: 1646-54.
-
(2008)
Blood
, vol.112
, pp. 1646-1654
-
-
Stock, W.1
La Sanford M, B.2
-
80
-
-
79952087452
-
Improved prognosis for older adolescents with acute lymphoblastic leukemia
-
Pui CH, Pei D, Campana D, et al. Improved prognosis for older adolescents with acute lymphoblastic leukemia. J Clin Oncol 2011; 29: 386-91.
-
(2011)
J Clin Oncol
, vol.29
, pp. 386-391
-
-
Pui, C.H.1
Pei, D.2
Campana, D.3
-
81
-
-
84862130973
-
Minimal residual disease monitoring in childhood acute lymphoblastic leukemia
-
Campana D. Minimal residual disease monitoring in childhood acute lymphoblastic leukemia. Curr Opin Hematol 2012; 19: 313-18.
-
(2012)
Curr Opin Hematol
, vol.19
, pp. 313-318
-
-
Campana, D.1
-
82
-
-
47049093795
-
Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: A Children's Oncology Group study
-
Borowitz MJ, Devidas M, Hunger SP, et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study. Blood 2008; 111: 5477-85.
-
(2008)
Blood
, vol.111
, pp. 5477-5485
-
-
Borowitz, M.J.1
Devidas, M.2
Hunger, S.P.3
-
83
-
-
77951441599
-
Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: Results in 3184 patients of the AIEOP-BFM ALL 2000 study
-
Conter V, Bartram CR, Valsecchi MG, et al. Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study. Blood 2010; 115: 3206-14.
-
(2010)
Blood
, vol.115
, pp. 3206-3214
-
-
Conter, V.1
Bartram, C.R.2
Valsecchi, M.G.3
-
84
-
-
80052172961
-
Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: Results of the AIEOP-BFM-ALL 2000 study
-
Schrappe M, Valsecchi MG, Bartram CR, et al. Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study. Blood 2011; 118: 2077-84.
-
(2011)
Blood
, vol.118
, pp. 2077-2084
-
-
Schrappe, M.1
Valsecchi, M.G.2
Bartram, C.R.3
-
85
-
-
70449711125
-
Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow
-
Basso G, Veltroni M, Valsecchi MG, et al. Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow. J Clin Oncol 2009; 27: 5168-74.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5168-5174
-
-
Basso, G.1
Veltroni, M.2
Valsecchi, M.G.3
-
86
-
-
84865709936
-
Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies
-
Gokbuget N, Kneba M, Raff T, et al. Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies. Blood 2012; 120: 1868-76.
-
(2012)
Blood
, vol.120
, pp. 1868-1876
-
-
Gokbuget, N.1
Kneba, M.2
Raff, T.3
-
87
-
-
77954727839
-
Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia
-
Stow P, Key L, Chen X, et al. Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia. Blood 2010; 115: 4657-63.
-
(2010)
Blood
, vol.115
, pp. 4657-4663
-
-
Stow, P.1
Key, L.2
Chen, X.3
-
88
-
-
79959450187
-
New markers for minimal residual disease detection in acute lymphoblastic leukemia
-
Coustan-Smith E, Song G, Clark C, et al. New markers for minimal residual disease detection in acute lymphoblastic leukemia. Blood 2011; 117: 6267-76.
-
(2011)
Blood
, vol.117
, pp. 6267-6276
-
-
Coustan-Smith, E.1
Song, G.2
Clark, C.3
-
89
-
-
78049529488
-
Glucocorticoid use in acute lymphoblastic leukaemia
-
Inaba H, Pui CH. Glucocorticoid use in acute lymphoblastic leukaemia. Lancet Oncol 2010; 11: 1096-106.
-
(2010)
Lancet Oncol
, vol.11
, pp. 1096-1106
-
-
Inaba, H.1
Pui, C.H.2
-
90
-
-
0038264383
-
Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: A report from the Children's Cancer Group
-
Bostrom BC, Sensel MR, Sather HN, et al. Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group. Blood 2003; 101: 3809-17.
-
(2003)
Blood
, vol.101
, pp. 3809-3817
-
-
Bostrom, B.C.1
Sensel, M.R.2
Sather, H.N.3
-
91
-
-
21344451860
-
Benefit of dexamethasone compared with prednisolone for childhood acute lymphoblastic leukaemia: Results of the UK Medical Research Council ALL97 randomized trial
-
Mitchell CD, Richards SM, Kinsey SE, Lilleyman J, Vora A, Eden TO. Benefit of dexamethasone compared with prednisolone for childhood acute lymphoblastic leukaemia: results of the UK Medical Research Council ALL97 randomized trial. Br J Haematol 2005; 129: 734-45.
-
(2005)
Br J Haematol
, vol.129
, pp. 734-745
-
-
Mitchell, C.D.1
Richards, S.M.2
Kinsey, S.E.3
Lilleyman, J.4
Vora, A.5
Eden, T.O.6
-
92
-
-
65749095348
-
Dexamethasone in induction can eliminate one third of all relapses in childhood acute lymphoblastic leukemia (ALL): Results of an international randomized trial in 3655 patients (trial AIEOP-BFM ALL 2000)
-
Schrappe M, Zimmermann M, Moricke A, et al. Dexamethasone in induction can eliminate one third of all relapses in childhood acute lymphoblastic leukemia (ALL): results of an international randomized trial in 3655 patients (trial AIEOP-BFM ALL 2000). Blood 2008; 112: 7s.
-
(2008)
Blood
, vol.112
-
-
Schrappe, M.1
Zimmermann, M.2
Moricke, A.3
-
93
-
-
80052428549
-
Dexamethasone (DEX) versus prednisone (PRED) during induction for children with high-risk acute lymphoblastic leukemia (HR-ALL): A report from the Children's Oncology Group study AALL0232
-
Winick N, Salzer W, Devidas M, et al. Dexamethasone (DEX) versus prednisone (PRED) during induction for children with high-risk acute lymphoblastic leukemia (HR-ALL): a report from the Children's Oncology Group study AALL0232. J Clin Oncol 2011; 29: 586s.
-
(2011)
J Clin Oncol
, vol.29
-
-
Winick, N.1
Salzer, W.2
Devidas, M.3
-
94
-
-
27244436741
-
No advantage of dexamethasone over prednisolone for the outcome of standard-and intermediate-risk childhood acute lymphoblastic leukemia in the Tokyo Children's Cancer Study Group L95-14 protocol
-
Igarashi S, Manabe A, Ohara A, et al. No advantage of dexamethasone over prednisolone for the outcome of standard-and intermediate-risk childhood acute lymphoblastic leukemia in the Tokyo Children's Cancer Study Group L95-14 protocol. J Clin Oncol 2005; 23: 6489-98.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6489-6498
-
-
Igarashi, S.1
Manabe, A.2
Ohara, A.3
-
95
-
-
77952647160
-
Dexamethasone(DEX) (6mg/sm/d) and prednisolone(PRED)(60mg/sm/d) in induction therapy of childhood ALL are equally effective: Results of the 2nd interim analysis of EORTC Trial 58951
-
Bertrand Y, Suciu S, Benoit Y, et al. Dexamethasone(DEX) (6mg/sm/d) and prednisolone(PRED)(60mg/sm/d) in induction therapy of childhood ALL are equally effective: results of the 2nd interim analysis of EORTC Trial 58951. Blood 2008; 112: 8s.
-
(2008)
Blood
, vol.112
-
-
Bertrand, Y.1
Suciu, S.2
Benoit, Y.3
-
96
-
-
84865168175
-
Pediatric acute lymphoblastic leukemia: Where are we going and how do we get there?
-
Pui CH, Mullighan CG, Evans WE, Relling MV. Pediatric acute lymphoblastic leukemia: where are we going and how do we get there? Blood 2012; 120: 1165-74.
-
(2012)
Blood
, vol.120
, pp. 1165-1174
-
-
Pui, C.H.1
Mullighan, C.G.2
Evans, W.E.3
Relling, M.V.4
-
97
-
-
78650976352
-
L-asparaginase treatment in acute lymphoblastic leukemia: A focus on Erwinia asparaginase
-
Pieters R, Hunger SP, Boos J, et al. L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase. Cancer 2011; 117: 238-49.
-
(2011)
Cancer
, vol.117
, pp. 238-249
-
-
Pieters, R.1
Hunger, S.P.2
Boos, J.3
-
98
-
-
77949895397
-
Intravenous PEG-asparaginase during remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia
-
Silverman LB, Supko JG, Stevenson KE, et al. Intravenous PEG-asparaginase during remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia. Blood 2010; 115: 1351-53.
-
(2010)
Blood
, vol.115
, pp. 1351-1353
-
-
Silverman, L.B.1
Supko, J.G.2
Stevenson, K.E.3
-
99
-
-
0035283163
-
Improved outcome for children with acute lymphoblastic leukemia: Results of Dana-Farber Consortium protocol 91-01
-
Silverman LB, Gelber RD, Dalton VK, et al. Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium protocol 91-01. Blood 2001; 97: 1211-18.
-
(2001)
Blood
, vol.97
, pp. 1211-1218
-
-
Silverman, L.B.1
Gelber, R.D.2
Dalton, V.K.3
-
100
-
-
82155178728
-
Anti-Escherichia coli asparaginase antibody levels determine the activity of second-line treatment with pegylated e coli asparaginase: A retrospective analysis within the ALL-BFM trials
-
Willer A, Gerss J, Konig T, et al. Anti-Escherichia coli asparaginase antibody levels determine the activity of second-line treatment with pegylated E coli asparaginase: a retrospective analysis within the ALL-BFM trials. Blood 2011; 118: 5774-82.
-
(2011)
Blood
, vol.118
, pp. 5774-5782
-
-
Willer, A.1
Gerss, J.2
Konig, T.3
-
101
-
-
42949114872
-
Asparaginase may influence dexamethasone pharmacokinetics in acute lymphoblastic leukemia
-
Yang L, Panetta JC, Cai X, et al. Asparaginase may influence dexamethasone pharmacokinetics in acute lymphoblastic leukemia. J Clin Oncol 2008; 26: 1932-39.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1932-1939
-
-
Yang, L.1
Panetta, J.C.2
Cai, X.3
-
102
-
-
84863116322
-
Dexamethasone exposure and asparaginase antibodies affect relapse risk in acute lymphoblastic leukemia
-
Kawedia JD, Liu C, Pei D, et al. Dexamethasone exposure and asparaginase antibodies affect relapse risk in acute lymphoblastic leukemia. Blood 2012; 119: 1658-64.
-
(2012)
Blood
, vol.119
, pp. 1658-1664
-
-
Kawedia, J.D.1
Liu, C.2
Pei, D.3
-
103
-
-
70449711127
-
Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: A Children's Oncology Group study
-
Schultz KR, Bowman WP, Aledo A, et al. Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a Children's Oncology Group study. J Clin Oncol 2009; 27: 5175-81.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5175-5181
-
-
Schultz, K.R.1
Bowman, W.P.2
Aledo, A.3
-
104
-
-
77957191745
-
First report of phase 2 study of dasatinib with hyper-CVAD for the frontline treatment of patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia
-
Ravandi F, O'Brien S, Thomas D, et al. First report of phase 2 study of dasatinib with hyper-CVAD for the frontline treatment of patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia. Blood 2010; 116: 2070-77.
-
(2010)
Blood
, vol.116
, pp. 2070-2077
-
-
Ravandi, F.1
O'Brien, S.2
Thomas, D.3
-
105
-
-
34948829146
-
Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: Interim results of a phase 2 study
-
Ottmann O, Dombret H, Martinelli G, et al. Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: interim results of a phase 2 study. Blood 2007; 110: 2309-15.
-
(2007)
Blood
, vol.110
, pp. 2309-2315
-
-
Ottmann, O.1
Dombret, H.2
Martinelli, G.3
-
106
-
-
51649111035
-
Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia
-
Porkka K, Koskenvesa P, Lundan T, et al. Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia. Blood 2008; 112: 1005-12.
-
(2008)
Blood
, vol.112
, pp. 1005-1012
-
-
Porkka, K.1
Koskenvesa, P.2
Lundan, T.3
-
107
-
-
0026658557
-
Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute lymphoblastic leukemia: A Pediatric Oncology Group study
-
Whitehead VM, Vuchich MJ, Lauer SJ, et al. Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute lymphoblastic leukemia: a Pediatric Oncology Group study. Blood 1992; 80: 1316-23.
-
(1992)
Blood
, vol.80
, pp. 1316-1323
-
-
Whitehead, V.M.1
Vuchich, M.J.2
Lauer, S.J.3
-
108
-
-
0033104709
-
Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia
-
Rots MG, Pieters R, Peters GJ, et al. Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia. Blood 1999; 93: 1677-83.
-
(1999)
Blood
, vol.93
, pp. 1677-1683
-
-
Rots, M.G.1
Pieters, R.2
Peters, G.J.3
-
109
-
-
66549095339
-
Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia
-
French D, Yang W, Cheng C, et al. Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia. Blood 2009; 113: 4512-20.
-
(2009)
Blood
, vol.113
, pp. 4512-4520
-
-
French, D.1
Yang, W.2
Cheng, C.3
-
110
-
-
73349098768
-
Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects
-
Trevino LR, Shimasaki N, Yang W, et al. Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. J Clin Oncol 2009; 27: 5972-8.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5972-5978
-
-
Trevino, L.R.1
Shimasaki, N.2
Yang, W.3
-
111
-
-
84855316334
-
Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition
-
Ramsey LB, Bruun GH, Yang W, et al. Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition. Genome Res 2012; 22: 1-8.
-
(2012)
Genome Res
, vol.22
, pp. 1-8
-
-
Ramsey, L.B.1
Bruun, G.H.2
Yang, W.3
-
112
-
-
80052442548
-
Comparison of high-dose methotrexate (HD-MTX) with Capizzi methotrexate plus asparaginase (C-MTX/ASNase) in children and young adults with high-risk acute lymphoblastic leukemia (HR-ALL): A report from the Children's Oncology Group study AALL0232
-
Larsen E, Salzer WL, Devidas M, et al. Comparison of high-dose methotrexate (HD-MTX) with Capizzi methotrexate plus asparaginase (C-MTX/ASNase) in children and young adults with high-risk acute lymphoblastic leukemia (HR-ALL): a report from the Children's Oncology Group study AALL0232. J Clin Oncol 2011; 29: 3s.
-
(2011)
J Clin Oncol
, vol.29
-
-
Larsen, E.1
Salzer, W.L.2
Devidas, M.3
-
113
-
-
79955582395
-
Shortening infusion time for high-dose methotrexate alters antileukemic effects: A randomized prospective clinical trial
-
Mikkelsen TS, Sparreboom A, Cheng C, et al. Shortening infusion time for high-dose methotrexate alters antileukemic effects: a randomized prospective clinical trial. J Clin Oncol 2011; 29: 1771-78.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1771-1778
-
-
Mikkelsen, T.S.1
Sparreboom, A.2
Cheng, C.3
-
114
-
-
33750334632
-
High leucovorin doses during high-dose methotrexate treatment may reduce the cure rate in childhood acute lymphoblastic leukemia
-
Skarby TV, Anderson H, Heldrup J, Kanerva JA, Seidel H, Schmiegelow K. High leucovorin doses during high-dose methotrexate treatment may reduce the cure rate in childhood acute lymphoblastic leukemia. Leukemia 2006; 20: 1955-62.
-
(2006)
Leukemia
, vol.20
, pp. 1955-1962
-
-
Skarby, T.V.1
Anderson, H.2
Heldrup, J.3
Kanerva, J.A.4
Seidel, H.5
Schmiegelow, K.6
-
115
-
-
41949098006
-
Early postinduction intensification therapy improves survival for children and adolescents with high-risk acute lymphoblastic leukemia: A report from the Children's Oncology Group
-
Seibel NL, Steinherz PG, Sather HN, et al. Early postinduction intensification therapy improves survival for children and adolescents with high-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood 2008; 111: 2548-55.
-
(2008)
Blood
, vol.111
, pp. 2548-2555
-
-
Seibel, N.L.1
Steinherz, P.G.2
Sather, H.N.3
-
116
-
-
79960462879
-
Escalating intravenous methotrexate improves event-free survival in children with standard-risk acute lymphoblastic leukemia: A report from the Children's Oncology Group
-
Matloub Y, Bostrom BC, Hunger SP, et al. Escalating intravenous methotrexate improves event-free survival in children with standard-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood 2011; 118: 243-51.
-
(2011)
Blood
, vol.118
, pp. 243-251
-
-
Matloub, Y.1
Bostrom, B.C.2
Hunger, S.P.3
-
117
-
-
84865541969
-
Effect of alternate-week versus continuous dexamethasone scheduling on the risk of osteonecrosis in paediatric patients with acute lymphoblastic leukaemia: Results from the CCG-1961 randomised cohort trial
-
Mattano LA, Devidas M, Nachman JB, et al. Effect of alternate-week versus continuous dexamethasone scheduling on the risk of osteonecrosis in paediatric patients with acute lymphoblastic leukaemia: results from the CCG-1961 randomised cohort trial. Lancet Oncol 2012; 13: 906-15.
-
(2012)
Lancet Oncol
, vol.13
, pp. 906-915
-
-
Mattano, L.A.1
Devidas, M.2
Nachman, J.B.3
-
118
-
-
0141923920
-
Thioguanine offers no advantage over mercaptopurine in maintenance treatment of childhood ALL: Results of the randomized trial COALL-92
-
Harms DO, Gobel U, Spaar HJ, et al. Thioguanine offers no advantage over mercaptopurine in maintenance treatment of childhood ALL: results of the randomized trial COALL-92. Blood 2003; 102: 2736-40.
-
(2003)
Blood
, vol.102
, pp. 2736-2740
-
-
Harms, D.O.1
Gobel, U.2
Spaar, H.J.3
-
119
-
-
33749515604
-
Toxicity and efficacy of 6-thioguanine versus 6-mercaptopurine in childhood lymphoblastic leukaemia: A randomised trial
-
Vora A, Mitchell CD, Lennard L, et al. Toxicity and efficacy of 6-thioguanine versus 6-mercaptopurine in childhood lymphoblastic leukaemia: a randomised trial. Lancet 2006; 368: 1339-48.
-
(2006)
Lancet
, vol.368
, pp. 1339-1348
-
-
Vora, A.1
Mitchell, C.D.2
Lennard, L.3
-
120
-
-
77950998036
-
Oral 6-mercaptopurine versus oral 6-thioguanine and veno-occlusive disease in children with standard-risk acute lymphoblastic leukemia: Report of the Children's Oncology Group CCG-1952 clinical trial
-
Stork LC, Matloub Y, Broxson E, et al. Oral 6-mercaptopurine versus oral 6-thioguanine and veno-occlusive disease in children with standard-risk acute lymphoblastic leukemia: report of the Children's Oncology Group CCG-1952 clinical trial. Blood 2010; 115: 2740-48.
-
(2010)
Blood
, vol.115
, pp. 2740-2748
-
-
Stork, L.C.1
Matloub, Y.2
Broxson, E.3
-
121
-
-
79951809968
-
Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing
-
Relling MV, Gardner EE, Sandborn WJ, et al. Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing. Clin Pharmacol Ther 2011; 89: 387-91.
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 387-391
-
-
Relling, M.V.1
Gardner, E.E.2
Sandborn, W.J.3
-
122
-
-
67650355472
-
Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: Results from the NOPHO ALL-92 study
-
Schmiegelow K, Al-Modhwahi I, Andersen MK, et al. Methotrexate/6- mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study. Blood 2009; 113: 6077-84.
-
(2009)
Blood
, vol.113
, pp. 6077-6084
-
-
Schmiegelow, K.1
Al-Modhwahi, I.2
Andersen, M.K.3
-
123
-
-
84863923825
-
Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: A report from the Children's Oncology Group
-
Bhatia S, Landier W, Shangguan M, et al. Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: a report from the Children's Oncology Group. J Clin Oncol 2012; 30: 2094-101.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2094-2101
-
-
Bhatia, S.1
Landier, W.2
Shangguan, M.3
-
124
-
-
80053934578
-
Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells
-
Diouf B, Cheng Q, Krynetskaia NF, et al. Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells. Nat Med 2011; 17: 1298-303.
-
(2011)
Nat Med
, vol.17
, pp. 1298-1303
-
-
Diouf, B.1
Cheng, Q.2
Krynetskaia, N.F.3
-
125
-
-
23844556272
-
Chemotherapy versus allogeneic transplantation for very-high-risk childhood acute lymphoblastic leukaemia in first complete remission: Comparison by genetic randomisation in an international prospective study
-
Balduzzi A, Valsecchi MG, Uderzo C, et al. Chemotherapy versus allogeneic transplantation for very-high-risk childhood acute lymphoblastic leukaemia in first complete remission: comparison by genetic randomisation in an international prospective study. Lancet 2005; 366: 635-42.
-
(2005)
Lancet
, vol.366
, pp. 635-642
-
-
Balduzzi, A.1
Valsecchi, M.G.2
Uderzo, C.3
-
126
-
-
77955886057
-
The outcome of full-intensity and reduced-intensity conditioning matched sibling or unrelated donor transplantation in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia in first and second complete remission
-
Marks DI, Wang T, Perez WS, et al. The outcome of full-intensity and reduced-intensity conditioning matched sibling or unrelated donor transplantation in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia in first and second complete remission. Blood 2010; 116: 366-74.
-
(2010)
Blood
, vol.116
, pp. 366-374
-
-
Marks, D.I.1
Wang, T.2
Perez, W.S.3
-
127
-
-
79960495326
-
High success rate of hematopoietic cell transplantation regardless of donor source in children with very high-risk leukemia
-
Leung W, Campana D, Yang J, et al. High success rate of hematopoietic cell transplantation regardless of donor source in children with very high-risk leukemia. Blood 2011; 118: 223-30.
-
(2011)
Blood
, vol.118
, pp. 223-230
-
-
Leung, W.1
Campana, D.2
Yang, J.3
-
128
-
-
34249899377
-
Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: A comparison study
-
Eapen M, Rubinstein P, Zhang M-J, et al. Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study. Lancet 2007; 369: 1947-54.
-
(2007)
Lancet
, vol.369
, pp. 1947-1954
-
-
Eapen, M.1
Rubinstein, P.2
Zhang, M.-J.3
-
129
-
-
77954031042
-
Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: A retrospective analysis
-
Eapen M, Rocha V, Sanz G, et al. Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis. Lancet Oncol 2010; 11: 653-60.
-
(2010)
Lancet Oncol
, vol.11
, pp. 653-660
-
-
Eapen, M.1
Rocha, V.2
Sanz, G.3
-
130
-
-
58549091682
-
Prognostic value of minimal residual disease quantification before allogeneic stem-cell transplantation in relapsed childhood acute lymphoblastic leukemia: The ALL-REZ BFM study group
-
Bader P, Kreyenberg H, Henze GH, et al. Prognostic value of minimal residual disease quantification before allogeneic stem-cell transplantation in relapsed childhood acute lymphoblastic leukemia: the ALL-REZ BFM study group. J Clin Oncol 2009; 27: 377-84.
-
(2009)
J Clin Oncol
, vol.27
, pp. 377-384
-
-
Bader, P.1
Kreyenberg, H.2
Henze, G.H.3
-
131
-
-
84864047454
-
Detectable minimal residual disease before hematopoietic cell transplantation is prognostic but does not preclude cure for children with very-high-risk leukemia
-
Leung W, Pui CH, Coustan-Smith E, et al. Detectable minimal residual disease before hematopoietic cell transplantation is prognostic but does not preclude cure for children with very-high-risk leukemia. Blood 2012; 120: 468-72.
-
(2012)
Blood
, vol.120
, pp. 468-472
-
-
Leung, W.1
Pui, C.H.2
Coustan-Smith, E.3
-
132
-
-
84859534539
-
Outcomes after induction failure in childhood acute lymphoblastic leukemia
-
Schrappe M, Hunger SP, Pui CH, et al. Outcomes after induction failure in childhood acute lymphoblastic leukemia. N Engl J Med 2012; 366: 1371-81.
-
(2012)
N Engl J Med
, vol.366
, pp. 1371-1381
-
-
Schrappe, M.1
Hunger, S.P.2
Pui, C.H.3
-
133
-
-
79951999971
-
Analysis of the role of hematopoietic stem-cell transplantation in infants with acute lymphoblastic leukemia in first remission and MLL gene rearrangements: A report from the Children's Oncology Group
-
Dreyer ZE, Dinndorf PA, Camitta B, et al. Analysis of the role of hematopoietic stem-cell transplantation in infants with acute lymphoblastic leukemia in first remission and MLL gene rearrangements: a report from the Children's Oncology Group. J Clin Oncol 2011; 29: 214-22.
-
(2011)
J Clin Oncol
, vol.29
, pp. 214-222
-
-
Dreyer, Z.E.1
Dinndorf, P.A.2
Camitta, B.3
-
134
-
-
77957949594
-
Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: Results from the Interfant-99 study
-
Mann G, Attarbaschi A, Schrappe M, et al. Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: results from the Interfant-99 study. Blood 2010; 116: 2644-50.
-
(2010)
Blood
, vol.116
, pp. 2644-2650
-
-
Mann, G.1
Attarbaschi, A.2
Schrappe, M.3
-
135
-
-
40749099021
-
Current management and challenges of malignant disease in the CNS in paediatric leukaemia
-
Pui C-H, Howard SC. Current management and challenges of malignant disease in the CNS in paediatric leukaemia. Lancet Oncol 2008; 9: 257-68.
-
(2008)
Lancet Oncol
, vol.9
, pp. 257-268
-
-
Pui, C.-H.1
Howard, S.C.2
-
136
-
-
70349390630
-
Dexamethasone-based therapy for childhood acute lymphoblastic leukaemia: Results of the prospective Dutch Childhood Oncology Group (DCOG) protocol ALL-9 (1997-2004)
-
Veerman AJ, Kamps WA, van den Berg H, et al. Dexamethasone-based therapy for childhood acute lymphoblastic leukaemia: results of the prospective Dutch Childhood Oncology Group (DCOG) protocol ALL-9 (1997-2004). Lancet Oncol 2009; 10: 957-66.
-
(2009)
Lancet Oncol
, vol.10
, pp. 957-966
-
-
Veerman, A.J.1
Kamps, W.A.2
Van Den Berg, H.3
-
137
-
-
33747199596
-
Intrathecal triple therapy decreases central nervous system relapse but fails to improve event-free survival when compared with intrathecal methotrexate: Results of the Children's Cancer Group (CCG) 1952 study for standard-risk acute lymphoblastic leukemia, reported by the Children's Oncology Group
-
Matloub Y, Lindemulder S, Gaynon PS, et al. Intrathecal triple therapy decreases central nervous system relapse but fails to improve event-free survival when compared with intrathecal methotrexate: results of the Children's Cancer Group (CCG) 1952 study for standard-risk acute lymphoblastic leukemia, reported by the Children's Oncology Group. Blood 2006; 108: 1165-73.
-
(2006)
Blood
, vol.108
, pp. 1165-1173
-
-
Matloub, Y.1
Lindemulder, S.2
Gaynon, P.S.3
-
138
-
-
76249112147
-
Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options
-
Stumpel DJ, Schneider P, van Roon EH, et al. Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options. Blood 2009; 114: 5490-98.
-
(2009)
Blood
, vol.114
, pp. 5490-5498
-
-
Stumpel, D.J.1
Schneider, P.2
Van Roon, E.H.3
-
139
-
-
79960044951
-
MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L
-
Bernt KM, Zhu N, Sinha AU, et al. MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L. Cancer Cell 2011; 20: 66-78.
-
(2011)
Cancer Cell
, vol.20
, pp. 66-78
-
-
Bernt, K.M.1
Zhu, N.2
Sinha, A.U.3
-
140
-
-
84859161970
-
Novel antibody-based therapies for acute lymphoblastic leukemia
-
Hoelzer D. Novel antibody-based therapies for acute lymphoblastic leukemia. Hematology Am Soc Hematol Educ Program 2011; 2011: 243-49.
-
(2011)
Hematology Am Soc Hematol Educ Program
, vol.2011
, pp. 243-249
-
-
Hoelzer, D.1
-
141
-
-
77956240944
-
Chemoimmunotherapy with a modified hyper-CVAD and rituximab regimen improves outcome in de novo Philadelphia chromosome-negative precursor B-lineage acute lymphoblastic leukemia
-
Thomas DA, O'Brien S, Faderl S, et al. Chemoimmunotherapy with a modified hyper-CVAD and rituximab regimen improves outcome in de novo Philadelphia chromosome-negative precursor B-lineage acute lymphoblastic leukemia. J Clin Oncol 2010; 28: 3880-89.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3880-3889
-
-
Thomas, D.A.1
O'Brien, S.2
Faderl, S.3
-
142
-
-
79959312575
-
Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival
-
Topp MS, Kufer P, Gokbuget N, et al. Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival. J Clin Oncol 2011; 29: 2493-98.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2493-2498
-
-
Topp, M.S.1
Kufer, P.2
Gokbuget, N.3
|