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Volumn 153, Issue 3, 2013, Pages 590-600

The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; HISTONE H3K36ME3; PROTEIN MUTS; PROTEIN MUTS ALPHA; UNCLASSIFIED DRUG;

EID: 84876943255     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2013.03.025     Document Type: Article
Times cited : (480)

References (66)
  • 1
    • 77955203926 scopus 로고    scopus 로고
    • Quantifying colocalization by correlation: The Pearson correlation coefficient is superior to the Mander's overlap coefficient
    • J. Adler, and I. Parmryd Quantifying colocalization by correlation: the Pearson correlation coefficient is superior to the Mander's overlap coefficient Cytometry A 77 2010 733 742
    • (2010) Cytometry A , vol.77 , pp. 733-742
    • Adler, J.1    Parmryd, I.2
  • 2
    • 36749030517 scopus 로고    scopus 로고
    • Analysis of dynamic changes in post-translational modifications of human histones during cell cycle by mass spectrometry
    • D. Bonenfant, H. Towbin, M. Coulot, P. Schindler, D.R. Mueller, and J. van Oostrum Analysis of dynamic changes in post-translational modifications of human histones during cell cycle by mass spectrometry Mol. Cell. Proteomics 6 2007 1917 1932
    • (2007) Mol. Cell. Proteomics , vol.6 , pp. 1917-1932
    • Bonenfant, D.1    Towbin, H.2    Coulot, M.3    Schindler, P.4    Mueller, D.R.5    Van Oostrum, J.6
  • 3
    • 0034711275 scopus 로고    scopus 로고
    • Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes
    • A.B. Clark, F. Valle, K. Drotschmann, R.K. Gary, and T.A. Kunkel Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes J. Biol. Chem. 275 2000 36498 36501
    • (2000) J. Biol. Chem. , vol.275 , pp. 36498-36501
    • Clark, A.B.1    Valle, F.2    Drotschmann, K.3    Gary, R.K.4    Kunkel, T.A.5
  • 4
    • 28844503379 scopus 로고    scopus 로고
    • Human mismatch repair: Reconstitution of a nick-directed bidirectional reaction
    • N. Constantin, L. Dzantiev, F.A. Kadyrov, and P. Modrich Human mismatch repair: reconstitution of a nick-directed bidirectional reaction J. Biol. Chem. 280 2005 39752 39761
    • (2005) J. Biol. Chem. , vol.280 , pp. 39752-39761
    • Constantin, N.1    Dzantiev, L.2    Kadyrov, F.A.3    Modrich, P.4
  • 7
    • 0029070143 scopus 로고
    • Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells
    • J.T. Drummond, G.M. Li, M.J. Longley, and P. Modrich Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells Science 268 1995 1909 1912
    • (1995) Science , vol.268 , pp. 1909-1912
    • Drummond, J.T.1    Li, G.M.2    Longley, M.J.3    Modrich, P.4
  • 8
    • 0030885951 scopus 로고    scopus 로고
    • DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair
    • J.T. Drummond, J. Genschel, E. Wolf, and P. Modrich DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair Proc. Natl. Acad. Sci. USA 94 1997 10144 10149
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10144-10149
    • Drummond, J.T.1    Genschel, J.2    Wolf, E.3    Modrich, P.4
  • 9
    • 77953170322 scopus 로고    scopus 로고
    • Histone methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma
    • G. Duns, E. van den Berg, I. van Duivenbode, J. Osinga, H. Hollema, R.M. Hofstra, and K. Kok Histone methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma Cancer Res. 70 2010 4287 4291
    • (2010) Cancer Res. , vol.70 , pp. 4287-4291
    • Duns, G.1    Van Den Berg, E.2    Van Duivenbode, I.3    Osinga, J.4    Hollema, H.5    Hofstra, R.M.6    Kok, K.7
  • 10
    • 38549139593 scopus 로고    scopus 로고
    • Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation
    • J.W. Edmunds, L.C. Mahadevan, and A.L. Clayton Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation EMBO J. 27 2008 406 420
    • (2008) EMBO J. , vol.27 , pp. 406-420
    • Edmunds, J.W.1    Mahadevan, L.C.2    Clayton, A.L.3
  • 11
    • 0029042130 scopus 로고
    • Identification of mismatch repair genes and their role in the development of cancer
    • R. Fishel, and R.D. Kolodner Identification of mismatch repair genes and their role in the development of cancer Curr. Opin. Genet. Dev. 5 1995 382 395
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 382-395
    • Fishel, R.1    Kolodner, R.D.2
  • 12
    • 0033764146 scopus 로고    scopus 로고
    • Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex
    • H. Flores-Rozas, D. Clark, and R.D. Kolodner Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex Nat. Genet. 26 2000 375 378
    • (2000) Nat. Genet. , vol.26 , pp. 375-378
    • Flores-Rozas, H.1    Clark, D.2    Kolodner, R.D.3
  • 16
    • 0031456973 scopus 로고    scopus 로고
    • The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch
    • S. Gradia, S. Acharya, and R. Fishel The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch Cell 91 1997 995 1005
    • (1997) Cell , vol.91 , pp. 995-1005
    • Gradia, S.1    Acharya, S.2    Fishel, R.3
  • 17
    • 0037158899 scopus 로고    scopus 로고
    • Mismatch repair deficiency in hematological malignancies with microsatellite instability
    • L. Gu, B. Cline-Brown, F. Zhang, L. Qiu, and G.M. Li Mismatch repair deficiency in hematological malignancies with microsatellite instability Oncogene 21 2002 5758 5764
    • (2002) Oncogene , vol.21 , pp. 5758-5764
    • Gu, L.1    Cline-Brown, B.2    Zhang, F.3    Qiu, L.4    Li, G.M.5
  • 18
    • 34548761416 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs
    • J.M. Harrington, and R.D. Kolodner Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs Mol. Cell. Biol. 27 2007 6546 6554
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 6546-6554
    • Harrington, J.M.1    Kolodner, R.D.2
  • 19
    • 0025340001 scopus 로고
    • Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines
    • J. Holmes Jr., S. Clark, and P. Modrich Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines Proc. Natl. Acad. Sci. USA 87 1990 5837 5841
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5837-5841
    • Holmes Jr., J.1    Clark, S.2    Modrich, P.3
  • 20
    • 81855189485 scopus 로고    scopus 로고
    • Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates
    • H. Hombauer, C.S. Campbell, C.E. Smith, A. Desai, and R.D. Kolodner Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates Cell 147 2011 1040 1053
    • (2011) Cell , vol.147 , pp. 1040-1053
    • Hombauer, H.1    Campbell, C.S.2    Smith, C.E.3    Desai, A.4    Kolodner, R.D.5
  • 21
    • 84455194209 scopus 로고    scopus 로고
    • Mismatch repair, but not heteroduplex rejection, is temporally coupled to DNA replication
    • H. Hombauer, A. Srivatsan, C.D. Putnam, and R.D. Kolodner Mismatch repair, but not heteroduplex rejection, is temporally coupled to DNA replication Science 334 2011 1713 1716
    • (2011) Science , vol.334 , pp. 1713-1716
    • Hombauer, H.1    Srivatsan, A.2    Putnam, C.D.3    Kolodner, R.D.4
  • 22
    • 55449088400 scopus 로고    scopus 로고
    • Recruitment of mismatch repair proteins to the site of DNA damage in human cells
    • Z. Hong, J. Jiang, K. Hashiguchi, M. Hoshi, L. Lan, and A. Yasui Recruitment of mismatch repair proteins to the site of DNA damage in human cells J. Cell Sci. 121 2008 3146 3154
    • (2008) J. Cell Sci. , vol.121 , pp. 3146-3154
    • Hong, Z.1    Jiang, J.2    Hashiguchi, K.3    Hoshi, M.4    Lan, L.5    Yasui, A.6
  • 25
    • 79952580115 scopus 로고    scopus 로고
    • CAF-I-dependent control of degradation of the discontinuous strands during mismatch repair
    • L.Y. Kadyrova, E.R. Blanko, and F.A. Kadyrov CAF-I-dependent control of degradation of the discontinuous strands during mismatch repair Proc. Natl. Acad. Sci. USA 108 2011 2753 2758
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 2753-2758
    • Kadyrova, L.Y.1    Blanko, E.R.2    Kadyrov, F.A.3
  • 26
    • 0031017268 scopus 로고    scopus 로고
    • Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
    • M.F. Kane, M. Loda, G.M. Gaida, J. Lipman, R. Mishra, H. Goldman, J.M. Jessup, and R. Kolodner Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines Cancer Res. 57 1997 808 811
    • (1997) Cancer Res. , vol.57 , pp. 808-811
    • Kane, M.F.1    Loda, M.2    Gaida, G.M.3    Lipman, J.4    Mishra, R.5    Goldman, H.6    Jessup, J.M.7    Kolodner, R.8
  • 27
    • 0027292234 scopus 로고
    • An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair
    • A. Kat, W.G. Thilly, W.H. Fang, M.J. Longley, G.M. Li, and P. Modrich An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair Proc. Natl. Acad. Sci. USA 90 1993 6424 6428
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6424-6428
    • Kat, A.1    Thilly, W.G.2    Fang, W.H.3    Longley, M.J.4    Li, G.M.5    Modrich, P.6
  • 28
    • 0035868951 scopus 로고    scopus 로고
    • HMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci
    • H.E. Kleczkowska, G. Marra, T. Lettieri, and J. Jiricny hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci Genes Dev. 15 2001 724 736
    • (2001) Genes Dev. , vol.15 , pp. 724-736
    • Kleczkowska, H.E.1    Marra, G.2    Lettieri, T.3    Jiricny, J.4
  • 29
    • 0029784320 scopus 로고    scopus 로고
    • Biochemistry and genetics of eukaryotic mismatch repair
    • R. Kolodner Biochemistry and genetics of eukaryotic mismatch repair Genes Dev. 10 1996 1433 1442
    • (1996) Genes Dev. , vol.10 , pp. 1433-1442
    • Kolodner, R.1
  • 32
    • 38049125557 scopus 로고    scopus 로고
    • Mechanisms and functions of DNA mismatch repair
    • G.M. Li Mechanisms and functions of DNA mismatch repair Cell Res. 18 2008 85 98
    • (2008) Cell Res. , vol.18 , pp. 85-98
    • Li, G.M.1
  • 33
    • 70450237030 scopus 로고    scopus 로고
    • Evidence that nucleosomes inhibit mismatch repair in eukaryotic cells
    • F. Li, L. Tian, L. Gu, and G.M. Li Evidence that nucleosomes inhibit mismatch repair in eukaryotic cells J. Biol. Chem. 284 2009 33056 33061
    • (2009) J. Biol. Chem. , vol.284 , pp. 33056-33061
    • Li, F.1    Tian, L.2    Gu, L.3    Li, G.M.4
  • 36
    • 0029868110 scopus 로고    scopus 로고
    • Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair
    • G.T. Marsischky, N. Filosi, M.F. Kane, and R. Kolodner Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair Genes Dev. 10 1996 407 420
    • (1996) Genes Dev. , vol.10 , pp. 407-420
    • Marsischky, G.T.1    Filosi, N.2    Kane, M.F.3    Kolodner, R.4
  • 37
    • 20444435104 scopus 로고    scopus 로고
    • Analysis of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 complexes with DNA using a reversible DNA end-blocking system
    • M.L. Mendillo, D.J. Mazur, and R.D. Kolodner Analysis of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 complexes with DNA using a reversible DNA end-blocking system J. Biol. Chem. 280 2005 22245 22257
    • (2005) J. Biol. Chem. , vol.280 , pp. 22245-22257
    • Mendillo, M.L.1    Mazur, D.J.2    Kolodner, R.D.3
  • 38
    • 0029943449 scopus 로고    scopus 로고
    • Mismatch repair in replication fidelity, genetic recombination, and cancer biology
    • P. Modrich, and R. Lahue Mismatch repair in replication fidelity, genetic recombination, and cancer biology Annu. Rev. Biochem. 65 1996 101 133
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 101-133
    • Modrich, P.1    Lahue, R.2
  • 41
    • 0037445248 scopus 로고    scopus 로고
    • Role of DNA mismatch repair defects in the pathogenesis of human cancer
    • P. Peltomäki Role of DNA mismatch repair defects in the pathogenesis of human cancer J. Clin. Oncol. 21 2003 1174 1179
    • (2003) J. Clin. Oncol. , vol.21 , pp. 1174-1179
    • Peltomäki, P.1
  • 42
    • 74549138158 scopus 로고    scopus 로고
    • Chaperoning histones during DNA replication and repair
    • M. Ransom, B.K. Dennehey, and J.K. Tyler Chaperoning histones during DNA replication and repair Cell 140 2010 183 195
    • (2010) Cell , vol.140 , pp. 183-195
    • Ransom, M.1    Dennehey, B.K.2    Tyler, J.K.3
  • 43
    • 67649923717 scopus 로고    scopus 로고
    • Robust methods for purification of histones from cultured mammalian cells with the preservation of their native modifications
    • P. Rodriguez-Collazo, S.H. Leuba, and J. Zlatanova Robust methods for purification of histones from cultured mammalian cells with the preservation of their native modifications Nucleic Acids Res. 37 2009 e81
    • (2009) Nucleic Acids Res. , vol.37 , pp. 81
    • Rodriguez-Collazo, P.1    Leuba, S.H.2    Zlatanova, J.3
  • 44
    • 77952994784 scopus 로고    scopus 로고
    • Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types
    • T. Ryba, I. Hiratani, J. Lu, M. Itoh, M. Kulik, J. Zhang, T.C. Schulz, A.J. Robins, S. Dalton, and D.M. Gilbert Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types Genome Res. 20 2010 761 770
    • (2010) Genome Res. , vol.20 , pp. 761-770
    • Ryba, T.1    Hiratani, I.2    Lu, J.3    Itoh, M.4    Kulik, M.5    Zhang, J.6    Schulz, T.C.7    Robins, A.J.8    Dalton, S.9    Gilbert, D.M.10
  • 46
    • 84865248380 scopus 로고    scopus 로고
    • Chromatin organization is a major influence on regional mutation rates in human cancer cells
    • B. Schuster-Böckler, and B. Lehner Chromatin organization is a major influence on regional mutation rates in human cancer cells Nature 488 2012 504 507
    • (2012) Nature , vol.488 , pp. 504-507
    • Schuster-Böckler, B.1    Lehner, B.2
  • 47
    • 34248579736 scopus 로고    scopus 로고
    • The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA
    • S.S. Shell, C.D. Putnam, and R.D. Kolodner The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA Mol. Cell 26 2007 565 578
    • (2007) Mol. Cell , vol.26 , pp. 565-578
    • Shell, S.S.1    Putnam, C.D.2    Kolodner, R.D.3
  • 48
    • 38949113141 scopus 로고    scopus 로고
    • Beta clamp directs localization of mismatch repair in Bacillus subtilis
    • L.A. Simmons, B.W. Davies, A.D. Grossman, and G.C. Walker Beta clamp directs localization of mismatch repair in Bacillus subtilis Mol. Cell 29 2008 291 301
    • (2008) Mol. Cell , vol.29 , pp. 291-301
    • Simmons, L.A.1    Davies, B.W.2    Grossman, A.D.3    Walker, G.C.4
  • 50
    • 2442670292 scopus 로고    scopus 로고
    • Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase
    • L. Stojic, N. Mojas, P. Cejka, M. Di Pietro, S. Ferrari, G. Marra, and J. Jiricny Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase Genes Dev. 18 2004 1331 1344
    • (2004) Genes Dev. , vol.18 , pp. 1331-1344
    • Stojic, L.1    Mojas, N.2    Cejka, P.3    Di Pietro, M.4    Ferrari, S.5    Marra, G.6    Jiricny, J.7
  • 51
    • 0025777777 scopus 로고
    • Heteroduplex repair in extracts of human HeLa cells
    • D.C. Thomas, J.D. Roberts, and T.A. Kunkel Heteroduplex repair in extracts of human HeLa cells J. Biol. Chem. 266 1991 3744 3751
    • (1991) J. Biol. Chem. , vol.266 , pp. 3744-3751
    • Thomas, D.C.1    Roberts, J.D.2    Kunkel, T.A.3
  • 52
    • 0028301255 scopus 로고
    • Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability
    • A. Umar, J.C. Boyer, D.C. Thomas, D.C. Nguyen, J.I. Risinger, J. Boyd, Y. Ionov, M. Perucho, and T.A. Kunkel Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability J. Biol. Chem. 269 1994 14367 14370
    • (1994) J. Biol. Chem. , vol.269 , pp. 14367-14370
    • Umar, A.1    Boyer, J.C.2    Thomas, D.C.3    Nguyen, D.C.4    Risinger, J.I.5    Boyd, J.6    Ionov, Y.7    Perucho, M.8    Kunkel, T.A.9
  • 57
    • 0028243081 scopus 로고
    • RNA polymerase II transcription is concentrated outside replication domains throughout S-phase
    • D.G. Wansink, E.E. Manders, I. van der Kraan, J.A. Aten, R. van Driel, and L. de Jong RNA polymerase II transcription is concentrated outside replication domains throughout S-phase J. Cell Sci. 107 1994 1449 1456
    • (1994) J. Cell Sci. , vol.107 , pp. 1449-1456
    • Wansink, D.G.1    Manders, E.E.2    Van Der Kraan, I.3    Aten, J.A.4    Van Driel, R.5    De Jong, L.6
  • 59
    • 58049206591 scopus 로고    scopus 로고
    • The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation
    • S.M. Yoh, J.S. Lucas, and K.A. Jones The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation Genes Dev. 22 2008 3422 3434
    • (2008) Genes Dev. , vol.22 , pp. 3422-3434
    • Yoh, S.M.1    Lucas, J.S.2    Jones, K.A.3
  • 63
    • 0032534069 scopus 로고    scopus 로고
    • A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
    • C.R. Boland, S.N. Thibodeau, S.R. Hamilton, D. Sidransky, J.R. Eshleman, R.W. Burt, S.J. Meltzer, M.A. Rodriguez-Bigas, R. Fodde, G.N. Ranzani, and S. Srivastava A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer Cancer Res. 58 1998 5248 5257
    • (1998) Cancer Res. , vol.58 , pp. 5248-5257
    • Boland, C.R.1    Thibodeau, S.N.2    Hamilton, S.R.3    Sidransky, D.4    Eshleman, J.R.5    Burt, R.W.6    Meltzer, S.J.7    Rodriguez-Bigas, M.A.8    Fodde, R.9    Ranzani, G.N.10    Srivastava, S.11
  • 64
    • 0029621851 scopus 로고
    • The microsatellite mutator phenotype of colon cancer cells is often recessive
    • S. Casares, Y. Ionov, H.Y. Ge, E. Stanbridge, and M. Perucho The microsatellite mutator phenotype of colon cancer cells is often recessive Oncogene 11 1995 2303 2310
    • (1995) Oncogene , vol.11 , pp. 2303-2310
    • Casares, S.1    Ionov, Y.2    Ge, H.Y.3    Stanbridge, E.4    Perucho, M.5
  • 65
    • 2342425404 scopus 로고    scopus 로고
    • Differential requirement for proliferating cell nuclear antigen in 5′ and 3′ nick-directed excision in human mismatch repair
    • S. Guo, S.R. Presnell, F. Yuan, Y. Zhang, L. Gu, and G.M. Li Differential requirement for proliferating cell nuclear antigen in 5′ and 3′ nick-directed excision in human mismatch repair J. Biol. Chem. 279 2004 16912 16917
    • (2004) J. Biol. Chem. , vol.279 , pp. 16912-16917
    • Guo, S.1    Presnell, S.R.2    Yuan, F.3    Zhang, Y.4    Gu, L.5    Li, G.M.6
  • 66
    • 0029951332 scopus 로고    scopus 로고
    • Differences in the spectrum of spontaneous mutations in the hprt gene between tumor cells of the microsatellite mutator phenotype
    • S. Malkhosyan, A. McCarty, H. Sawai, and M. Perucho Differences in the spectrum of spontaneous mutations in the hprt gene between tumor cells of the microsatellite mutator phenotype Mutat. Res. 316 1996 249 259
    • (1996) Mutat. Res. , vol.316 , pp. 249-259
    • Malkhosyan, S.1    McCarty, A.2    Sawai, H.3    Perucho, M.4


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