The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia

Blood

Volumn 111, Issue 9, 2008, Pages 4668-4680

  Van Vlierberghe, Pieter ^a   Van Grotel, Martine ^a   Tchinda, Joëlle ^b   Lee, Charles ^b   Beverloo, H Berna ^c   Van Der Spek, Peter J ^c   Stubbs, Andrew ^c   Cools, Jan ^d   Nagata, Kyosuke ^e   Fornerod, Maarten ^f   Buijs Gladdines, Jessica ^a   Horstmann, Martin ^g   Van Wering, Elisabeth R ^h   Soulier, Jean ⁱ   Pieters, Rob ^a   Meijerink, Jules P P ^a  

^a SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^e UNIVERSITY OF TSUKUBA   (Japan)

^f NETHERLANDS CANCER INSTITUTE   (Netherlands)

^g Childhood Acute Lymphoblastic Leukemia (COALL)   (Germany)

^h DCOG Dutch Childhood Oncology Group   (Netherlands)

ⁱ SAINT LOUIS HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; ONCOPROTEIN; PROTEIN NUP214; PROTEIN SET; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HOXA; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; HOXA PROTEIN; NONHISTONE PROTEIN; NUCLEOPORIN; NUP214 PROTEIN, HUMAN; SET PROTEIN, HUMAN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHILD; CHROMOSOME ABERRATION; CHROMOSOME DELETION; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; SCHOOL CHILD; T CELL LEUKEMIA; TRANSCRIPTION INITIATION; CLUSTER ANALYSIS; GENE DELETION; GENETICS; PHYSIOLOGY; RECURRENT DISEASE; T CELL LEUKEMIA LYMPHOMA;

CELL DIFFERENTIATION; CHILD; CHROMOSOMAL PROTEINS, NON-HISTONE; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; HOMEODOMAIN PROTEINS; HUMANS; LEUKEMIA-LYMPHOMA, ADULT T-CELL; NUCLEAR PORE COMPLEX PROTEINS; ONCOGENE PROTEINS, FUSION; PROTEIN BINDING; RECURRENCE; SEQUENCE DELETION; TRANSCRIPTION FACTORS;

EID: 47149084727     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2007-09-111872     Document Type: Article

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