메뉴 건너뛰기




Volumn 355, Issue 3, 2014, Pages 557-576

Regulation of the endothelial barrier function: A filum granum of cellular forces, Rho-GTPase signaling and microenvironment

Author keywords

Endothelial barrier; Extracellular matrix stiffness; Permeability; Rho GTPases; Traction forces

Indexed keywords

GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PROTEIN CDC42; RAC1 PROTEIN; RAP1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 84899472758     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-014-1828-6     Document Type: Review
Times cited : (34)

References (238)
  • 1
    • 0242266953 scopus 로고    scopus 로고
    • RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development
    • 10.1101/gad.1134603 280621 14597666
    • Adini I, Rabinovitz I, Sun JF, Prendergast GC, Benjamin LE (2003) RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development. Genes Dev 17:2721-32. doi: 10.1101/gad.1134603
    • (2003) Genes Dev , vol.17 , pp. 2721-2732
    • Adini, I.1    Rabinovitz, I.2    Sun, J.F.3    Prendergast, G.C.4    Benjamin, L.E.5
  • 2
    • 84869091543 scopus 로고    scopus 로고
    • Endothelial cell heterogeneity
    • 10.1101/cshperspect.a006429 3253027 22315715
    • Aird WC (2012) Endothelial cell heterogeneity. Cold Spring Harb Perspect Med 2:a006429. doi: 10.1101/cshperspect.a006429
    • (2012) Cold Spring Harb Perspect Med , vol.2 , pp. 006429
    • Aird, W.C.1
  • 3
    • 84884387786 scopus 로고    scopus 로고
    • Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization
    • 10.1083/jcb.201301115 3776352 24019534
    • Ando K, Fukuhara S, Moriya T, Obara Y, Nakahata N, Mochizuki N (2013) Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization. J Cell Biol 202:901-16. doi: 10.1083/jcb.201301115
    • (2013) J Cell Biol , vol.202 , pp. 901-916
    • Ando, K.1    Fukuhara, S.2    Moriya, T.3    Obara, Y.4    Nakahata, N.5    Mochizuki, N.6
  • 4
    • 47749089703 scopus 로고    scopus 로고
    • Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: Role of cortactin
    • 10.1529/biophysj.107.127167 2440433 18408039
    • Arce FT, Whitlock JL, Birukova AA, Birukov KG, Arnsdorf MF, Lal R, Garcia JGN, Dudek SM (2008) Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin. Biophys J 95:886-94. doi: 10.1529/biophysj.107.127167
    • (2008) Biophys J , vol.95 , pp. 886-894
    • Arce, F.T.1    Whitlock, J.L.2    Birukova, A.A.3    Birukov, K.G.4    Arnsdorf, M.F.5    Lal, R.6    Garcia, J.G.N.7    Dudek, S.M.8
  • 5
    • 0942268723 scopus 로고    scopus 로고
    • Rho GTPases have diverse effects on the organization of the actin filament system
    • 10.1042/BJ20031041 1223866 14521508
    • Aspenström P, Fransson A, Saras J (2004) Rho GTPases have diverse effects on the organization of the actin filament system. Biochem J 377:327-37. doi: 10.1042/BJ20031041
    • (2004) Biochem J , vol.377 , pp. 327-337
    • Aspenström, P.1    Fransson, A.2    Saras, J.3
  • 6
    • 0028674873 scopus 로고
    • Differentiation of endothelial cells: Analysis of the constitutive and activated endothelial cell phenotypes
    • 10.1002/bies.950161208 7840769
    • Augustin HG, Kozian DH, Johnson RC (1994) Differentiation of endothelial cells: analysis of the constitutive and activated endothelial cell phenotypes. Bioessays 16:901-6. doi: 10.1002/bies.950161208
    • (1994) Bioessays , vol.16 , pp. 901-906
    • Augustin, H.G.1    Kozian, D.H.2    Johnson, R.C.3
  • 7
    • 60749096085 scopus 로고    scopus 로고
    • Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system
    • 10.1038/nrm2639 19234476
    • Augustin HG, Koh GY, Thurston G, Alitalo K (2009) Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system. Nat Rev Mol Cell Biol 10:165-77. doi: 10.1038/nrm2639
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 165-177
    • Augustin, H.G.1    Koh, G.Y.2    Thurston, G.3    Alitalo, K.4
  • 8
    • 57749177096 scopus 로고    scopus 로고
    • Endothelial dysfunction and diabetes: Roles of hyperglycemia, impaired insulin signaling and obesity
    • 10.1007/s00441-008-0685-6 18941783
    • Bakker W, Eringa EC, Sipkema P, van Hinsbergh VWM (2009) Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity. Cell Tissue Res 335:165-89. doi: 10.1007/s00441-008-0685-6
    • (2009) Cell Tissue Res , vol.335 , pp. 165-189
    • Bakker, W.1    Eringa, E.C.2    Sipkema, P.3    Van Hinsbergh, V.W.M.4
  • 10
    • 44149106107 scopus 로고    scopus 로고
    • CAMP induced Rac 1-mediated cytoskeletal reorganization in microvascular endothelium
    • 10.1007/s00418-008-0422-y 18392843
    • Baumer Y, Drenckhahn D, Waschke J (2008) cAMP induced Rac 1-mediated cytoskeletal reorganization in microvascular endothelium. Histochem Cell Biol 129:765-78. doi: 10.1007/s00418-008-0422-y
    • (2008) Histochem Cell Biol , vol.129 , pp. 765-778
    • Baumer, Y.1    Drenckhahn, D.2    Waschke, J.3
  • 11
    • 0037444477 scopus 로고    scopus 로고
    • Cadherin function probed by laser tweezer and single molecule fluorescence in vascular endothelial cells
    • 10.1242/jcs.00322 12584244
    • Baumgartner W (2003) Cadherin function probed by laser tweezer and single molecule fluorescence in vascular endothelial cells. J Cell Sci 116:1001-1011. doi: 10.1242/jcs.00322
    • (2003) J Cell Sci , vol.116 , pp. 1001-1011
    • Baumgartner, W.1
  • 13
    • 0033847194 scopus 로고    scopus 로고
    • RGD-Dependent Vacuolation and Lumen Formation Observed during Endothelial Cell Morphogenesis in Three-Dimensional Fibrin Matrices Involves the αvβ3 and α5β1 Integrins
    • doi: 10.1016/S0002-9440(10)65038-9
    • Bayless KJ, Salazar R, Davis GE (2000) RGD-Dependent Vacuolation and Lumen Formation Observed during Endothelial Cell Morphogenesis in Three-Dimensional Fibrin Matrices Involves the αvβ3 and α5β1 Integrins. Am J Pathol 156:1673-1683. doi: 10.1016/S0002- 9440(10)65038-9
    • (2000) Am J Pathol , vol.156 , pp. 1673-1683
    • Bayless, K.J.1    Salazar, R.2    Davis, G.E.3
  • 14
    • 74149095063 scopus 로고    scopus 로고
    • Driving Rho GTPase activity in endothelial cells regulates barrier integrity
    • 10.1160/TH09-06-0403 20062930
    • Beckers CML, van Hinsbergh VWM, Van Nieuw Amerongen GP (2010) Driving Rho GTPase activity in endothelial cells regulates barrier integrity. Thromb Haemost 103:40-55. doi: 10.1160/TH09-06-0403
    • (2010) Thromb Haemost , vol.103 , pp. 40-55
    • Beckers, C.M.L.1    Van Hinsbergh, V.W.M.2    Van Nieuw Amerongen, G.P.3
  • 15
    • 0036469826 scopus 로고    scopus 로고
    • Flexible substrata for the detection of cellular traction forces
    • 11849971
    • Beningo KA, Wang Y-L (2002) Flexible substrata for the detection of cellular traction forces. Trends Cell Biol 12:79-84
    • (2002) Trends Cell Biol , vol.12 , pp. 79-84
    • Beningo, K.A.1    Wang, Y.-L.2
  • 16
    • 59849092005 scopus 로고    scopus 로고
    • Small GTPases in mechanosensitive regulation of endothelial barrier
    • 10.1016/j.mvr.2008.09.006 2673191 18938185
    • Birukov KG (2009) Small GTPases in mechanosensitive regulation of endothelial barrier. Microvasc Res 77:46-52. doi: 10.1016/j.mvr.2008.09.006
    • (2009) Microvasc Res , vol.77 , pp. 46-52
    • Birukov, K.G.1
  • 17
    • 0347989369 scopus 로고    scopus 로고
    • Role of Rho GTPases in thrombin-induced lung vascular endothelial cells barrier dysfunction
    • 10.1016/j.mvr.2003.09.007 14709404
    • Birukova AA, Smurova K, Birukov KG, Kaibuchi K, Garcia JGN, Verin AD (2004) Role of Rho GTPases in thrombin-induced lung vascular endothelial cells barrier dysfunction. Microvasc Res 67:64-77. doi: 10.1016/j.mvr.2003.09.007
    • (2004) Microvasc Res , vol.67 , pp. 64-77
    • Birukova, A.A.1    Smurova, K.2    Birukov, K.G.3    Kaibuchi, K.4    Garcia, J.G.N.5    Verin, A.D.6
  • 19
    • 73449118596 scopus 로고    scopus 로고
    • Rap1 mediates protective effects of iloprost against ventilator-induced lung injury
    • 10.1152/japplphysiol.00462.2009 2793200 19850733
    • Birukova AA, Fu P, Xing J, Birukov KG (2009) Rap1 mediates protective effects of iloprost against ventilator-induced lung injury. J Appl Physiol 107:1900-10. doi: 10.1152/japplphysiol.00462.2009
    • (2009) J Appl Physiol , vol.107 , pp. 1900-1910
    • Birukova, A.A.1    Fu, P.2    Xing, J.3    Birukov, K.G.4
  • 20
    • 77952761852 scopus 로고    scopus 로고
    • Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability
    • 10.1152/ajplung.00263.2009
    • Birukova AA, Fu P, Xing J (2010) Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability. Am J Physiol Lung Cell Mol Physiol 298:837-48. doi: 10.1152/ajplung.00263.2009
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.298 , pp. 837-848
    • Birukova, A.A.1    Fu, P.2    Xing, J.3
  • 21
    • 84876321031 scopus 로고    scopus 로고
    • Endothelial barrier disruption and recovery is controlled by substrate stiffness
    • 10.1016/j.mvr.2012.12.006 23296034
    • Birukova AA, Tian X, Cokic I, Beckham Y, Gardel ML, Birukov KG (2013a) Endothelial barrier disruption and recovery is controlled by substrate stiffness. Microvasc Res 87:50-7. doi: 10.1016/j.mvr.2012.12.006
    • (2013) Microvasc Res , vol.87 , pp. 50-57
    • Birukova, A.A.1    Tian, X.2    Cokic, I.3    Beckham, Y.4    Gardel, M.L.5    Birukov, K.G.6
  • 22
    • 84883375711 scopus 로고    scopus 로고
    • Rap-afadin axis in control of Rho signaling and endothelial barrier recovery
    • 10.1091/mbc.E13-02-0098 3756920 23864716
    • Birukova AA, Tian X, Tian Y, Higginbotham K, Birukov KG (2013b) Rap-afadin axis in control of Rho signaling and endothelial barrier recovery. Mol Biol Cell 24:2678-88. doi: 10.1091/mbc.E13-02-0098
    • (2013) Mol Biol Cell , vol.24 , pp. 2678-2688
    • Birukova, A.A.1    Tian, X.2    Tian, Y.3    Higginbotham, K.4    Birukov, K.G.5
  • 23
    • 0034213327 scopus 로고    scopus 로고
    • Rho GTPases and their effector proteins
    • 1221060 10816416
    • Bishop A, Hall A (2000) Rho GTPases and their effector proteins. Biochem J 348(Pt 2):241-55
    • (2000) Biochem J , vol.348 , Issue.PART 2 , pp. 241-255
    • Bishop, A.1    Hall, A.2
  • 24
    • 0032806558 scopus 로고    scopus 로고
    • Small GTPases and regulation of cadherin dependent cell-cell adhesion
    • 395699 10694939
    • Braga VM (1999) Small GTPases and regulation of cadherin dependent cell-cell adhesion. Mol Pathol 52:197-202
    • (1999) Mol Pathol , vol.52 , pp. 197-202
    • Braga, V.M.1
  • 25
    • 34250204186 scopus 로고    scopus 로고
    • Cdc42 regulates the restoration of endothelial adherens junctions and permeability
    • 10.1016/j.tcm.2007.03.004 17574122
    • Broman MT, Mehta D, Malik AB (2007) Cdc42 regulates the restoration of endothelial adherens junctions and permeability. Trends Cardiovasc Med 17:151-6. doi: 10.1016/j.tcm.2007.03.004
    • (2007) Trends Cardiovasc Med , vol.17 , pp. 151-156
    • Broman, M.T.1    Mehta, D.2    Malik, A.B.3
  • 27
    • 67349260722 scopus 로고    scopus 로고
    • Endothelial actin and cell stiffness is modulated by substrate stiffness in 2D and 3D
    • 10.1016/j.jbiomech.2009.02.012 2893018 19356760
    • Byfield FJ, Reen RK, Shentu T-P, Levitan I, Gooch KJ (2009) Endothelial actin and cell stiffness is modulated by substrate stiffness in 2D and 3D. J Biomech 42:1114-9. doi: 10.1016/j.jbiomech.2009.02.012
    • (2009) J Biomech , vol.42 , pp. 1114-1119
    • Byfield, F.J.1    Reen, R.K.2    Shentu, T.-P.3    Levitan, I.4    Gooch, K.J.5
  • 28
    • 72149087688 scopus 로고    scopus 로고
    • Exogenous and endogenous force regulation of endothelial cell behavior
    • 10.1016/j.jbiomech.2009.09.012 19815215
    • Califano JP, Reinhart-King CA (2010) Exogenous and endogenous force regulation of endothelial cell behavior. J Biomech 43:79-86. doi: 10.1016/j.jbiomech.2009.09.012
    • (2010) J Biomech , vol.43 , pp. 79-86
    • Califano, J.P.1    Reinhart-King, C.A.2
  • 30
    • 56349169536 scopus 로고    scopus 로고
    • Mechanotransduction - A field pulling together?
    • 10.1242/jcs.023507 18843115
    • Chen CS (2008) Mechanotransduction - a field pulling together? J Cell Sci 121:3285-92. doi: 10.1242/jcs.023507
    • (2008) J Cell Sci , vol.121 , pp. 3285-3292
    • Chen, C.S.1
  • 31
    • 84863203031 scopus 로고    scopus 로고
    • Endothelial cell-specific FGD5 involvement in vascular pruning defines neovessel fate in mice
    • doi: 10.1161/CIRCULATIONAHA.111.064030
    • Cheng C, Haasdijk R, Tempel D, van de Kamp EHM, Herpers R, Bos F, Den Dekker WK, Blonden LAJ, de Jong R, Bürgisser PE, Chrifi I, Biessen EAL, Dimmeler S, Schulte-Merker S, Duckers HJ (2012) Endothelial cell-specific FGD5 involvement in vascular pruning defines neovessel fate in mice. Circulation 125:3142-58. doi: 10.1161/CIRCULATIONAHA.111.064030
    • (2012) Circulation , vol.125 , pp. 3142-3158
    • Cheng C, H.1
  • 32
    • 84874433733 scopus 로고    scopus 로고
    • Regulation of Small GTPases by GEFs, GAPs, and GDIs
    • 10.1152/physrev.00003.2012 23303910
    • Cherfils J, Zeghouf M (2013) Regulation of Small GTPases by GEFs, GAPs, and GDIs. Physiol Rev 93:269-309. doi: 10.1152/physrev.00003.2012
    • (2013) Physiol Rev , vol.93 , pp. 269-309
    • Cherfils, J.1    Zeghouf, M.2
  • 33
    • 84857729635 scopus 로고    scopus 로고
    • Epithelial protein lost in neoplasm (EPLIN) interacts with α-catenin and actin filaments in endothelial cells and stabilizes vascular capillary network in vitro
    • doi: 10.1074/jbc.M111.328682
    • Chervin-Pétinot A, Courçon M, Almagro S, Nicolas A, Grichine A, Grunwald D, Prandini M-H, Huber P, Gulino-Debrac D (2012) Epithelial protein lost in neoplasm (EPLIN) interacts with α-catenin and actin filaments in endothelial cells and stabilizes vascular capillary network in vitro. J Biol Chem 287:7556-72. doi: 10.1074/jbc.M111.328682
    • (2012) J Biol Chem , vol.287 , pp. 7556-7572
    • Chervin-Pétinot A, C.1
  • 34
    • 41949111990 scopus 로고    scopus 로고
    • Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1bdeficient mice
    • 10.1182/blood-2007-08-109710 2254536 17993608
    • Chrzanowska-Wodnicka M, Kraus AE, Gale D, White GC, Vansluys J (2008) Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1bdeficient mice. Blood 111:2647-56. doi: 10.1182/blood-2007-08-109710
    • (2008) Blood , vol.111 , pp. 2647-2656
    • Chrzanowska-Wodnicka, M.1    Kraus, A.E.2    Gale, D.3    White, G.C.4    Vansluys, J.5
  • 35
    • 79251600675 scopus 로고    scopus 로고
    • Key role of the RhoA/Rho kinase system in pulmonary hypertension
    • 10.1016/j.pupt.2010.09.001 20833255
    • Connolly MJ, Aaronson PI (2011) Key role of the RhoA/Rho kinase system in pulmonary hypertension. Pulm Pharmacol Ther 24:1-14. doi: 10.1016/j.pupt.2010. 09.001
    • (2011) Pulm Pharmacol Ther , vol.24 , pp. 1-14
    • Connolly, M.J.1    Aaronson, P.I.2
  • 36
    • 84888103520 scopus 로고    scopus 로고
    • Flow-dependent cellular mechanotransduction in atherosclerosis
    • 10.1242/jcs.138313 24190880
    • Conway DE, Schwartz MA (2013) Flow-dependent cellular mechanotransduction in atherosclerosis. J Cell Sci 126:5101-9. doi: 10.1242/jcs.138313
    • (2013) J Cell Sci , vol.126 , pp. 5101-5109
    • Conway, D.E.1    Schwartz, M.A.2
  • 37
    • 84878611663 scopus 로고    scopus 로고
    • Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1
    • 10.1016/j.cub.2013.04.049 23684974
    • Conway DE, Breckenridge MT, Hinde E, Gratton E, Chen CS, Schwartz MA (2013) Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Curr Biol 23:1024-30. doi: 10.1016/j.cub.2013. 04.049
    • (2013) Curr Biol , vol.23 , pp. 1024-1030
    • Conway, D.E.1    Breckenridge, M.T.2    Hinde, E.3    Gratton, E.4    Chen, C.S.5    Schwartz, M.A.6
  • 38
    • 15944404246 scopus 로고    scopus 로고
    • VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly
    • 10.1182/blood-2004-06-2244 15604224
    • Crosby CV, Fleming PA, Argraves WS, Corada M, Zanetta L, Dejana E, Drake CJ (2005) VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly. Blood 105:2771-6. doi: 10.1182/blood-2004-06-2244
    • (2005) Blood , vol.105 , pp. 2771-2776
    • Crosby, C.V.1    Fleming, P.A.2    Argraves, W.S.3    Corada, M.4    Zanetta, L.5    Dejana, E.6    Drake, C.J.7
  • 39
    • 14944377651 scopus 로고    scopus 로고
    • Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase
    • 10.1182/blood-2004-05-1987 15374886
    • Cullere X, Shaw SK, Andersson L, Hirahashi J, Luscinskas FW, Mayadas TN (2005) Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase. Blood 105:1950-5. doi: 10.1182/blood-2004-05-1987
    • (2005) Blood , vol.105 , pp. 1950-1955
    • Cullere, X.1    Shaw, S.K.2    Andersson, L.3    Hirahashi, J.4    Luscinskas, F.W.5    Mayadas, T.N.6
  • 40
    • 1842632667 scopus 로고    scopus 로고
    • Endothelial cell-cell junctions: Happy together
    • 10.1038/nrm1357 15071551
    • Dejana E (2004) Endothelial cell-cell junctions: happy together. Nat Rev Mol Cell Biol 5:261-70. doi: 10.1038/nrm1357
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 261-270
    • Dejana, E.1
  • 41
    • 84879860325 scopus 로고    scopus 로고
    • Endothelial adherens junctions at a glance
    • 10.1242/jcs.124529 23781019
    • Dejana E, Orsenigo F (2013) Endothelial adherens junctions at a glance. J Cell Sci 126(Pt 12):2545-9. doi: 10.1242/jcs.124529
    • (2013) J Cell Sci , vol.126 , Issue.PART 12 , pp. 2545-2549
    • Dejana, E.1    Orsenigo, F.2
  • 42
    • 59649092177 scopus 로고    scopus 로고
    • The control of vascular integrity by endothelial cell junctions: Molecular basis and pathological implications
    • 10.1016/j.devcel.2009.01.004 19217423
    • Dejana E, Tournier-Lasserve E, Weinstein BM (2009) The control of vascular integrity by endothelial cell junctions: molecular basis and pathological implications. Dev Cell 16:209-21. doi: 10.1016/j.devcel.2009.01.004
    • (2009) Dev Cell , vol.16 , pp. 209-221
    • Dejana, E.1    Tournier-Lasserve, E.2    Weinstein, B.M.3
  • 43
    • 59149094538 scopus 로고    scopus 로고
    • Stretching single talin rod molecules activates vinculin binding
    • 10.1126/science.1162912 19179532
    • Del Rio A, Perez-Jimenez R, Liu R, Roca-Cusachs P, Fernandez JM, Sheetz MP (2009) Stretching single talin rod molecules activates vinculin binding. Science 323:638-41. doi: 10.1126/science.1162912
    • (2009) Science , vol.323 , pp. 638-641
    • Del Rio, A.1    Perez-Jimenez, R.2    Liu, R.3    Roca-Cusachs, P.4    Fernandez, J.M.5    Sheetz, M.P.6
  • 44
    • 1442306222 scopus 로고    scopus 로고
    • Membrane and acto-myosin tension promote clustering of adhesion proteins
    • Please check captured Familyname of author (Kurdi R Al) if corect. Please check captured Familyname of author (Kurdi R Al) if corect
    • Delanoë-Ayari H, Al Kurdi R, Vallade M, Gulino-debrac D, Riveline D (2004) Membrane and acto-myosin tension promote clustering of adhesion proteins. Proc Natl Acad Sci 101:2229-2234
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 2229-2234
    • Delanoë-Ayari H, A.1
  • 45
    • 0029880446 scopus 로고    scopus 로고
    • Imaging the traction stresses exerted by locomoting cells with the elastic substratum method
    • 10.1016/S0006-3495(96)79767-9 1225170 8785360
    • Dembo M, Oliver T, Ishihara A, Jacobson K (1996) Imaging the traction stresses exerted by locomoting cells with the elastic substratum method. Biophys J 70:2008-22. doi: 10.1016/S0006-3495(96)79767-9
    • (1996) Biophys J , vol.70 , pp. 2008-2022
    • Dembo, M.1    Oliver, T.2    Ishihara, A.3    Jacobson, K.4
  • 47
    • 27944497333 scopus 로고    scopus 로고
    • Tissue cells feel and respond to the stiffness of their substrate
    • 10.1126/science.1116995 16293750 80
    • Discher DE, Janmey P, Wang Y-L (2005) Tissue cells feel and respond to the stiffness of their substrate. Science 310:1139-43. doi: 10.1126/science. 1116995, 80-
    • (2005) Science , vol.310 , pp. 1139-1143
    • Discher, D.E.1    Janmey, P.2    Wang, Y.-L.3
  • 48
    • 26944440432 scopus 로고    scopus 로고
    • RhoGDIs revisited: Novel roles in Rho regulation
    • 10.1111/j.1600-0854.2005.00335.x 16190977
    • Dransart E, Olofsson B, Cherfils J (2005) RhoGDIs revisited: novel roles in Rho regulation. Traffic 6:957-66. doi: 10.1111/j.1600-0854.2005.00335.x
    • (2005) Traffic , vol.6 , pp. 957-966
    • Dransart, E.1    Olofsson, B.2    Cherfils, J.3
  • 49
    • 28344439885 scopus 로고    scopus 로고
    • Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly
    • 10.1016/j.cell.2005.09.021 3369825 16325583
    • Drees F, Pokutta S, Yamada S, Nelson WJ, Weis WI (2005) Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly. Cell 123:903-15. doi: 10.1016/j.cell.2005.09.021
    • (2005) Cell , vol.123 , pp. 903-915
    • Drees, F.1    Pokutta, S.2    Yamada, S.3    Nelson, W.J.4    Weis, W.I.5
  • 50
    • 84873835618 scopus 로고    scopus 로고
    • Measurement of local permeability at subcellular level in cell models of agonist- and ventilator-induced lung injury
    • 10.1038/labinvest.2012.159 3668557 23212101
    • Dubrovskyi O, Birukova AA, Birukov KG (2013) Measurement of local permeability at subcellular level in cell models of agonist- and ventilator-induced lung injury. Lab Invest 93:254-63. doi: 10.1038/labinvest. 2012.159
    • (2013) Lab Invest , vol.93 , pp. 254-263
    • Dubrovskyi, O.1    Birukova, A.A.2    Birukov, K.G.3
  • 51
    • 0034807581 scopus 로고    scopus 로고
    • Cytoskeletal regulation of pulmonary vascular permeability
    • 11568129
    • Dudek SM, Garcia JGN (2001) Cytoskeletal regulation of pulmonary vascular permeability. J Appl Physiol 91:1487-1500
    • (2001) J Appl Physiol , vol.91 , pp. 1487-1500
    • Dudek, S.M.1    Garcia, J.G.N.2
  • 53
    • 40949099049 scopus 로고    scopus 로고
    • Organization of multiprotein complexes at cell-cell junctions
    • 10.1007/s00418-008-0418-7 2413109 18365233
    • Ebnet K (2008) Organization of multiprotein complexes at cell-cell junctions. Histochem Cell Biol 130:1-20. doi: 10.1007/s00418-008-0418-7
    • (2008) Histochem Cell Biol , vol.130 , pp. 1-20
    • Ebnet, K.1
  • 54
    • 80054043810 scopus 로고    scopus 로고
    • Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A
    • 10.1038/nature10430 3204864 21926999
    • Ehrlicher AJ, Nakamura F, Hartwig JH, Weitz DA, Stossel TP (2011) Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A. Nature 478:260-3. doi: 10.1038/nature10430
    • (2011) Nature , vol.478 , pp. 260-263
    • Ehrlicher, A.J.1    Nakamura, F.2    Hartwig, J.H.3    Weitz, D.A.4    Stossel, T.P.5
  • 55
    • 0347319161 scopus 로고    scopus 로고
    • Substrate compliance versus ligand density in cell on gel responses
    • 10.1016/S0006-3495(04)74140-5 1303831 14695306
    • Engler A, Bacakova L, Newman C, Hategan A, Griffin M, Discher DE (2004) Substrate compliance versus ligand density in cell on gel responses. Biophys J 86:617-28. doi: 10.1016/S0006-3495(04)74140-5
    • (2004) Biophys J , vol.86 , pp. 617-628
    • Engler, A.1    Bacakova, L.2    Newman, C.3    Hategan, A.4    Griffin, M.5    Discher, D.E.6
  • 56
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification
    • 10.1016/j.cell.2006.06.044 16923388
    • Engler AJ, Sen S, Sweeney HL, Discher DE (2006) Matrix elasticity directs stem cell lineage specification. Cell 126:677-89. doi: 10.1016/j.cell.2006.06. 044
    • (2006) Cell , vol.126 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 57
    • 0942279704 scopus 로고    scopus 로고
    • Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes
    • 10.1021/bi036026v 14744125
    • Erickson JW, Cerione RA (2004) Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes. Biochemistry 43:837-42. doi: 10.1021/bi036026v
    • (2004) Biochemistry , vol.43 , pp. 837-842
    • Erickson, J.W.1    Cerione, R.A.2
  • 58
    • 0032555506 scopus 로고    scopus 로고
    • Thrombin inactivates myosin light chain phosphatase via Rho and its target Rho kinase in human endothelial cells
    • 10.1074/jbc.273.34.21867 9705325
    • Essler M, Amano M, Kruse HJ, Kaibuchi K, Weber PC, Aepfelbacher M (1998) Thrombin inactivates myosin light chain phosphatase via Rho and its target Rho kinase in human endothelial cells. J Biol Chem 273:21867-74. doi: 10.1074/jbc.273.34.21867
    • (1998) J Biol Chem , vol.273 , pp. 21867-21874
    • Essler, M.1    Amano, M.2    Kruse, H.J.3    Kaibuchi, K.4    Weber, P.C.5    Aepfelbacher, M.6
  • 59
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • 10.1038/nature01148 12478284
    • Etienne-Manneville S, Hall A (2002) Rho GTPases in cell biology. Nature 420:629-35. doi: 10.1038/nature01148
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 60
    • 79960277917 scopus 로고    scopus 로고
    • A hitchhiker's guide to mechanobiology
    • doi: 10.1016/j.devcel.2011.06.015
    • Eyckmans J, Boudou T, Yu X, Chen CS (2011) A hitchhiker's guide to mechanobiology. Dev Cell 21:35-47. doi: 10.1016/j.devcel.2011.06.015
    • (2011) Dev Cell , vol.21 , pp. 35-47
    • Eyckmans, J.1    Boudou, T.2    Yu, X.3    Chen, C.S.4
  • 61
    • 0032491391 scopus 로고    scopus 로고
    • The Tight Junction Protein ZO-1 Establishes a Link between the Transmembrane Protein Occludin and the Actin Cytoskeleton
    • 10.1074/jbc.273.45.29745 9792688
    • Fanning AS (1998) The Tight Junction Protein ZO-1 Establishes a Link between the Transmembrane Protein Occludin and the Actin Cytoskeleton. J Biol Chem 273:29745-29753. doi: 10.1074/jbc.273.45.29745
    • (1998) J Biol Chem , vol.273 , pp. 29745-29753
    • Fanning, A.S.1
  • 62
    • 84884217926 scopus 로고    scopus 로고
    • CCM1-ICAP-1 complex controls β1 integrin-dependent endothelial contractility and fibronectin remodeling
    • doi: 10.1083/jcb.201303044
    • Faurobert E, Rome C, Lisowska J, Manet-Dupé S, Boulday G, Malbouyres M, Balland M, Bouin A-P, Kéramidas M, Bouvard D, Coll J-L, Ruggiero F, Tournier-Lasserve E, Albiges-Rizo C (2013) CCM1-ICAP-1 complex controls β1 integrin-dependent endothelial contractility and fibronectin remodeling. J Cell Biol 202:545-61. doi: 10.1083/jcb.201303044
    • (2013) J Cell Biol , vol.202 , pp. 545-561
    • Faurobert E, R.1
  • 65
    • 0037458579 scopus 로고    scopus 로고
    • Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis
    • doi: 10.1074/jbc.M208609200
    • Fransson A, Ruusala A, Aspenström P (2003) Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis. J Biol Chem 278:6495-502. doi: 10.1074/jbc.M208609200
    • (2003) J Biol Chem , vol.278 , pp. 6495-6502
    • Fransson A, R.1
  • 66
    • 11144305139 scopus 로고    scopus 로고
    • Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway
    • 10.1128/MCB.25.1.136-146.2005 538793 15601837
    • Fukuhara S, Sakurai A, Sano H, Yamagishi A, Somekawa S, Takakura N, Saito Y, Kangawa K, Mochizuki N (2005) Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway. Mol Cell Biol 25:136-46. doi: 10.1128/MCB.25.1.136-146.2005
    • (2005) Mol Cell Biol , vol.25 , pp. 136-146
    • Fukuhara, S.1    Sakurai, A.2    Sano, H.3    Yamagishi, A.4    Somekawa, S.5    Takakura, N.6    Saito, Y.7    Kangawa, K.8    Mochizuki, N.9
  • 67
    • 0025073547 scopus 로고
    • Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins
    • 2120668
    • Fukumoto Y, Kaibuchi K, Hori Y, Fujioka H, Araki S, Ueda T, Kikuchi A, Takai Y (1990) Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins. Oncogene 5:1321-8
    • (1990) Oncogene , vol.5 , pp. 1321-1328
    • Fukumoto, Y.1    Kaibuchi, K.2    Hori, Y.3    Fujioka, H.4    Araki, S.5    Ueda, T.6    Kikuchi, A.7    Takai, Y.8
  • 68
    • 0037175402 scopus 로고    scopus 로고
    • The relationship between force and focal complex development
    • 10.1083/jcb.200204153 2173098 12446745
    • Galbraith CG, Yamada KM, Sheetz MP (2002) The relationship between force and focal complex development. J Cell Biol 159:695-705. doi: 10.1083/jcb.200204153
    • (2002) J Cell Biol , vol.159 , pp. 695-705
    • Galbraith, C.G.1    Yamada, K.M.2    Sheetz, M.P.3
  • 69
    • 0034799675 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement
    • 10.1172/JCI12450 209379 11544274
    • Garcia JGN, Liu F, Verin AD, Birukova AA, Dechert MA, Gerthoffer WT, Bamberg JR, English D (2001) Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement. J Clin Invest 108:689-701. doi: 10.1172/JCI12450
    • (2001) J Clin Invest , vol.108 , pp. 689-701
    • Garcia, J.G.N.1    Liu, F.2    Verin, A.D.3    Birukova, A.A.4    Dechert, M.A.5    Gerthoffer, W.T.6    Bamberg, J.R.7    English, D.8
  • 70
    • 79960706295 scopus 로고    scopus 로고
    • The "invisible hand": Regulation of RHO GTPases by RHOGDIs
    • 10.1038/nrm3153 3260518 21779026
    • Garcia-Mata R, Boulter E, Burridge K (2011) The "invisible hand": regulation of RHO GTPases by RHOGDIs. Nat Rev Mol Cell Biol 12:493-504. doi: 10.1038/nrm3153
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 493-504
    • Garcia-Mata, R.1    Boulter, E.2    Burridge, K.3
  • 71
    • 34548028024 scopus 로고    scopus 로고
    • VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2
    • 10.1016/j.yexcr.2007.05.027 2034315 17686471
    • Garrett TA, Van Buul JD, Burridge K (2007) VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2. Exp Cell Res 313:3285-97. doi: 10.1016/j.yexcr.2007.05.027
    • (2007) Exp Cell Res , vol.313 , pp. 3285-3297
    • Garrett, T.A.1    Van Buul, J.D.2    Burridge, K.3
  • 72
    • 57749206415 scopus 로고    scopus 로고
    • Breaking the VE-cadherin bonds
    • 10.1016/j.febslet.2008.11.032 19059243
    • Gavard J (2009) Breaking the VE-cadherin bonds. FEBS Lett 583:1-6. doi: 10.1016/j.febslet.2008.11.032
    • (2009) FEBS Lett , vol.583 , pp. 1-6
    • Gavard, J.1
  • 73
    • 33750529948 scopus 로고    scopus 로고
    • VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin
    • 10.1038/ncb1486 17060906
    • Gavard J, Gutkind JS (2006) VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin. Nat Cell Biol 8:1223-34. doi: 10.1038/ncb1486
    • (2006) Nat Cell Biol , vol.8 , pp. 1223-1234
    • Gavard, J.1    Gutkind, J.S.2
  • 74
    • 37848998838 scopus 로고    scopus 로고
    • Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia
    • 10.1016/j.devcel.2007.10.019 18194650
    • Gavard J, Patel V, Gutkind JS (2008) Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia. Dev Cell 14:25-36. doi: 10.1016/j.devcel.2007.10.019
    • (2008) Dev Cell , vol.14 , pp. 25-36
    • Gavard, J.1    Patel, V.2    Gutkind, J.S.3
  • 75
    • 33646204388 scopus 로고    scopus 로고
    • Matrices with compliance comparable to that of brain tissue select neuronal over glial growth in mixed cortical cultures
    • 10.1529/biophysj.105.073114 1414567 16461391
    • Georges PC, Miller WJ, Meaney DF, Sawyer ES, Janmey PA (2006) Matrices with compliance comparable to that of brain tissue select neuronal over glial growth in mixed cortical cultures. Biophys J 90:3012-8. doi: 10.1529/biophysj.105.073114
    • (2006) Biophys J , vol.90 , pp. 3012-3018
    • Georges, P.C.1    Miller, W.J.2    Meaney, D.F.3    Sawyer, E.S.4    Janmey, P.A.5
  • 76
    • 0346455765 scopus 로고    scopus 로고
    • NAD(P)H oxidase mediates the endothelial barrier dysfunction induced by TNF-alpha
    • 10.1152/ajplung.00116.2003 12807699
    • Gertzberg N, Neumann P, Rizzo V, Johnson A (2004) NAD(P)H oxidase mediates the endothelial barrier dysfunction induced by TNF-alpha. Am J Physiol Lung Cell Mol Physiol 286:L37-48. doi: 10.1152/ajplung.00116.2003
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.286 , pp. 37-48
    • Gertzberg, N.1    Neumann, P.2    Rizzo, V.3    Johnson, A.4
  • 78
    • 49649125325 scopus 로고    scopus 로고
    • Tumorderived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro
    • 10.1073/pnas.0800835105 2516246 18685096
    • Ghosh K, Thodeti CK, Dudley AC, Mammoto A, Klagsbrun M, Ingber DE (2008) Tumorderived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. Proc Natl Acad Sci U S A 105:11305-10. doi: 10.1073/pnas.0800835105
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 11305-11310
    • Ghosh, K.1    Thodeti, C.K.2    Dudley, A.C.3    Mammoto, A.4    Klagsbrun, M.5    Ingber, D.E.6
  • 79
    • 84884149475 scopus 로고    scopus 로고
    • VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity
    • 10.1016/j.devcel.2013.08.020 24044891
    • Giannotta M, Trani M, Dejana E (2013) VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity. Dev Cell 26:441-54. doi: 10.1016/j.devcel.2013.08.020
    • (2013) Dev Cell , vol.26 , pp. 441-454
    • Giannotta, M.1    Trani, M.2    Dejana, E.3
  • 80
    • 0029119895 scopus 로고
    • Myosin light chain kinase-regulated endothelial cell contraction: The relationship between isometric tension, actin polymerization, and myosin phosphorylation
    • 7622562
    • Goeckeler ZM, Wysolmerski RB (1995) Myosin light chain kinase-regulated endothelial cell contraction: the relationship between isometric tension, actin polymerization, and myosin phosphorylation. J Cell Biol 130:613-27
    • (1995) J Cell Biol , vol.130 , pp. 613-627
    • Goeckeler, Z.M.1    Wysolmerski, R.B.2
  • 81
    • 79959407347 scopus 로고    scopus 로고
    • Broken barriers: A new take on sepsis pathogenesis
    • 10.1126/scitranslmed.3002011 21697528
    • Goldenberg NM, Steinberg BE, Slutsky AS, Lee WL (2011) Broken barriers: a new take on sepsis pathogenesis. Sci Transl Med 3:88ps25. doi: 10.1126/scitranslmed.3002011
    • (2011) Sci Transl Med , vol.3
    • Goldenberg, N.M.1    Steinberg, B.E.2    Slutsky, A.S.3    Lee, W.L.4
  • 82
  • 83
    • 0344306445 scopus 로고    scopus 로고
    • Repositioning of cells by mechanotaxis on surfaces with micropatterned Young's modulus
    • 10.1002/jbm.a.10585 12918044
    • Gray DS, Tien J, Chen CS (2003) Repositioning of cells by mechanotaxis on surfaces with micropatterned Young's modulus. J Biomed Mater Res A 66:605-14. doi: 10.1002/jbm.a.10585
    • (2003) J Biomed Mater Res A , vol.66 , pp. 605-614
    • Gray, D.S.1    Tien, J.2    Chen, C.S.3
  • 84
    • 81355148858 scopus 로고    scopus 로고
    • Rho protein crosstalk: Another social network?
    • 3221770 21924908
    • Guilluy C, Garcia-Mata R, Burridge K (2011a) Rho protein crosstalk: another social network? Trends Cell Biol 21:718-726
    • (2011) Trends Cell Biol , vol.21 , pp. 718-726
    • Guilluy, C.1    Garcia-Mata, R.2    Burridge, K.3
  • 86
    • 84899475682 scopus 로고    scopus 로고
    • Mechanotransduction at the basis of endothelial barrier function
    • 10.4161/tisb.24180 3879236 24665386
    • Gulino-Debrac D (2013) Mechanotransduction at the basis of endothelial barrier function. Tissue Barriers 1:e24180. doi: 10.4161/tisb.24180
    • (2013) Tissue Barriers , vol.1 , pp. 24180
    • Gulino-Debrac, D.1
  • 87
    • 84870209800 scopus 로고    scopus 로고
    • Rho family GTPases
    • 10.1042/BST20120103 23176484
    • Hall A (2012) Rho family GTPases. Biochem Soc Trans 40:1378-82. doi: 10.1042/BST20120103
    • (2012) Biochem Soc Trans , vol.40 , pp. 1378-1382
    • Hall, A.1
  • 88
    • 84865373665 scopus 로고    scopus 로고
    • Decoupling Substrate Stiffness, Spread Area, and Micropost Density: A Close Spatial Relationship between Traction Forces and Focal Adhesions
    • 10.1016/j.bpj.2012.07.023 3443781 22947925
    • Han SJ, Bielawski KS, Ting LH, Rodriguez ML, Sniadecki NJ (2012) Decoupling Substrate Stiffness, Spread Area, and Micropost Density: A Close Spatial Relationship between Traction Forces and Focal Adhesions. Biophys J 103:640-8. doi: 10.1016/j.bpj.2012.07.023
    • (2012) Biophys J , vol.103 , pp. 640-648
    • Han, S.J.1    Bielawski, K.S.2    Ting, L.H.3    Rodriguez, M.L.4    Sniadecki, N.J.5
  • 91
    • 39849100440 scopus 로고    scopus 로고
    • Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton
    • 10.1016/j.bbamem.2007.07.012 2682436 17854762
    • Hartsock A, Nelson WJ (2008) Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. Biochim Biophys Acta 1778:660-9. doi: 10.1016/j.bbamem.2007.07.012
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 660-669
    • Hartsock, A.1    Nelson, W.J.2
  • 92
    • 41149122298 scopus 로고    scopus 로고
    • Novel insights into FGD3, a putative GEF for Cdc42, that undergoes SCF(FWD1/beta-TrCP)-mediated proteasomal degradation analogous to that of its homologue FGD1 but regulates cell morphology and motility differently from FGD1
    • 10.1111/j.1365-2443.2008.01168.x 18363964
    • Hayakawa M, Matsushima M, Hagiwara H, Oshima T, Fujino T, Ando K, Kikugawa K, Tanaka H, Miyazawa K, Kitagawa M (2008) Novel insights into FGD3, a putative GEF for Cdc42, that undergoes SCF(FWD1/beta-TrCP)-mediated proteasomal degradation analogous to that of its homologue FGD1 but regulates cell morphology and motility differently from FGD1. Genes Cells 13:329-42. doi: 10.1111/j.1365-2443.2008.01168.x
    • (2008) Genes Cells , vol.13 , pp. 329-342
    • Hayakawa, M.1    Matsushima, M.2    Hagiwara, H.3    Oshima, T.4    Fujino, T.5    Ando, K.6    Kikugawa, K.7    Tanaka, H.8    Miyazawa, K.9    Kitagawa, M.10
  • 93
    • 84865385060 scopus 로고    scopus 로고
    • PKC and RhoA signals crosstalk in Escherichia coli endotoxin induced alterations in brain endothelial permeability
    • 10.1016/j.bbrc.2012.07.063 22846579
    • He F, Yin F, Omran A, Yang L, Xiang Q, Peng J (2012) PKC and RhoA signals crosstalk in Escherichia coli endotoxin induced alterations in brain endothelial permeability. Biochem Biophys Res Commun 425:182-8. doi: 10.1016/j.bbrc.2012.07.063
    • (2012) Biochem Biophys Res Commun , vol.425 , pp. 182-188
    • He, F.1    Yin, F.2    Omran, A.3    Yang, L.4    Xiang, Q.5    Peng, J.6
  • 95
    • 84855894827 scopus 로고    scopus 로고
    • The cytoskeletal mechanisms of cell-cell junction formation in endothelial cells
    • 10.1091/mbc.E11-08-0719 3258175 22090347
    • Hoelzle MK, Svitkina T (2012) The cytoskeletal mechanisms of cell-cell junction formation in endothelial cells. Mol Biol Cell 23:310-23. doi: 10.1091/mbc.E11-08-0719
    • (2012) Mol Biol Cell , vol.23 , pp. 310-323
    • Hoelzle, M.K.1    Svitkina, T.2
  • 96
    • 79960637431 scopus 로고    scopus 로고
    • Dynamic molecular processes mediate cellular mechanotransduction
    • 10.1038/nature10316 21776077
    • Hoffman BD, Grashoff C, Schwartz MA (2011) Dynamic molecular processes mediate cellular mechanotransduction. Nature 475:316-23. doi: 10.1038/nature10316
    • (2011) Nature , vol.475 , pp. 316-323
    • Hoffman, B.D.1    Grashoff, C.2    Schwartz, M.A.3
  • 97
    • 84876393236 scopus 로고    scopus 로고
    • RhoB controls endothelial cell morphogenesis in part via negative regulation of RhoA
    • 10.1186/2045-824X-4-1 3350406 22316440
    • Howe GA, Addison CL (2012) RhoB controls endothelial cell morphogenesis in part via negative regulation of RhoA. Vasc Cell 4:1. doi: 10.1186/2045-824X-4-1
    • (2012) Vasc Cell , vol.4 , pp. 1
    • Howe, G.A.1    Addison, C.L.2
  • 98
    • 57749116036 scopus 로고    scopus 로고
    • FGD2, a CDC42- specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles
    • 10.1074/jbc.M803957200 2590680 18838382
    • Huber C, Mårtensson A, Bokoch GM, Nemazee D, Gavin AL (2008) FGD2, a CDC42- specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles. J Biol Chem 283:34002-12. doi: 10.1074/jbc.M803957200
    • (2008) J Biol Chem , vol.283 , pp. 34002-34012
    • Huber, C.1    Mårtensson, A.2    Bokoch, G.M.3    Nemazee, D.4    Gavin, A.L.5
  • 100
    • 77955865809 scopus 로고    scopus 로고
    • The interaction of SRC kinase with beta3 integrin tails: A potential therapeutic target in thrombosis and cancer
    • 10.1100/tsw.2010.114
    • Huveneers S, Danen EHJ (2010) The interaction of SRC kinase with beta3 integrin tails: a potential therapeutic target in thrombosis and cancer. Sci World J 10:1100-5. doi: 10.1100/tsw.2010.114
    • (2010) Sci World J , vol.10 , pp. 1100-1105
    • Huveneers, S.1    Danen, E.H.J.2
  • 103
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • 10.1146/annurev.cellbio.21.020604.150721 16212495
    • Jaffe AB, Hall A (2005) Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol 21:247-69. doi: 10.1146/annurev.cellbio.21.020604.150721
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 104
    • 34247216078 scopus 로고    scopus 로고
    • Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: A newly recognized mechanism for sustaining ductal constriction
    • doi: 10.1161/CIRCULATIONAHA.106.649566
    • Kajimoto H, Hashimoto K, Bonnet SN, Haromy A, Harry G, Moudgil R, Nakanishi T, Rebeyka I, Thébaud B, Michelakis ED, Archer SL (2007) Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction. Circulation 115:1777-88. doi: 10.1161/CIRCULATIONAHA.106.649566
    • (2007) Circulation , vol.115 , pp. 1777-1788
    • Kajimoto H, H.1
  • 105
    • 21744460978 scopus 로고    scopus 로고
    • Ventricular arterial stiffening: Integrating the pathophysiology
    • 10.1161/01.HYP.0000168053.34306.d4 15911741
    • Kass DA (2005) Ventricular arterial stiffening: integrating the pathophysiology. Hypertension 46:185-93. doi: 10.1161/01.HYP.0000168053.34306.d4
    • (2005) Hypertension , vol.46 , pp. 185-193
    • Kass, D.A.1
  • 107
    • 27644497978 scopus 로고    scopus 로고
    • Cooperative effects of Rho and mechanical stretch on stress fiber organization
    • 10.1073/pnas.0506041102 1276069 16247009
    • Kaunas R, Nguyen P, Usami S, Chien S (2005) Cooperative effects of Rho and mechanical stretch on stress fiber organization. Proc Natl Acad Sci U S A 102:15895-900. doi: 10.1073/pnas.0506041102
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 15895-15900
    • Kaunas, R.1    Nguyen, P.2    Usami, S.3    Chien, S.4
  • 108
    • 84871337430 scopus 로고    scopus 로고
    • Single-molecule nanometry for biological physics
    • 10.1088/0034-4885/76/1/016601 3549428 23249673
    • Kim H, Ha T (2013) Single-molecule nanometry for biological physics. Rep Prog Phys 76:016601. doi: 10.1088/0034-4885/76/1/016601
    • (2013) Rep Prog Phys , vol.76 , pp. 016601
    • Kim, H.1    Ha, T.2
  • 109
    • 0033843942 scopus 로고    scopus 로고
    • Regulation of Angiogenesis in Vivo by Ligation of Integrin α5β1 with the Central Cell-Binding Domain of Fibronectin
    • doi: 10.1016/S0002-9440(10)65005-5
    • Kim S, Bell K, Mousa SA, Varner JA (2000) Regulation of Angiogenesis in Vivo by Ligation of Integrin α5β1 with the Central Cell-Binding Domain of Fibronectin. Am J Pathol 156:1345-1362. doi: 10.1016/S0002-9440(10) 65005-5
    • (2000) Am J Pathol , vol.156 , pp. 1345-1362
    • Kim, S.1    Bell, K.2    Mousa, S.A.3    Varner, J.A.4
  • 112
    • 34548791299 scopus 로고    scopus 로고
    • GDI-1 phosphorylation switch at serine 96 induces RhoA activation and increased endothelial permeability
    • 10.1128/MCB.00523-07 2099605 17636025
    • Knezevic N, Roy A, Timblin B, Konstantoulaki M, Sharma T, Malik AB, Mehta D (2007) GDI-1 phosphorylation switch at serine 96 induces RhoA activation and increased endothelial permeability. Mol Cell Biol 27:6323-33. doi: 10.1128/MCB.00523-07
    • (2007) Mol Cell Biol , vol.27 , pp. 6323-6333
    • Knezevic, N.1    Roy, A.2    Timblin, B.3    Konstantoulaki, M.4    Sharma, T.5    Malik, A.B.6    Mehta, D.7
  • 113
    • 64149094335 scopus 로고    scopus 로고
    • Tiam1 and Rac1 are required for platelet-activating factorinduced endothelial junctional disassembly and increase in vascular permeability
    • 10.1074/jbc.M808958200 2643508 19095647
    • Knezevic II, Predescu SA, Neamu RF, Gorovoy MS, Knezevic NM, Easington C, Malik AB, Predescu DN (2009) Tiam1 and Rac1 are required for platelet-activating factorinduced endothelial junctional disassembly and increase in vascular permeability. J Biol Chem 284:5381-94. doi: 10.1074/jbc.M808958200
    • (2009) J Biol Chem , vol.284 , pp. 5381-5394
    • Knezevic, I.I.1    Predescu, S.A.2    Neamu, R.F.3    Gorovoy, M.S.4    Knezevic, N.M.5    Easington, C.6    Malik, A.B.7    Predescu, D.N.8
  • 114
    • 0033106491 scopus 로고    scopus 로고
    • Homophilic adhesion by cadherins
    • 10.1016/S0959-440X(99)80038-4 10322209
    • Koch AW, Bozic D, Pertz O, Engel J (1999) Homophilic adhesion by cadherins. Curr Opin Struct Biol 9:275-81. doi: 10.1016/S0959-440X(99)80038-4
    • (1999) Curr Opin Struct Biol , vol.9 , pp. 275-281
    • Koch, A.W.1    Bozic, D.2    Pertz, O.3    Engel, J.4
  • 115
    • 0026519128 scopus 로고
    • Isometric contraction by fibroblasts and endothelial cells in tissue culture: A quantitative study
    • 1556157
    • Kolodney MS, Wysolmerski RB (1992) Isometric contraction by fibroblasts and endothelial cells in tissue culture: a quantitative study. J Cell Biol 117:73-82
    • (1992) J Cell Biol , vol.117 , pp. 73-82
    • Kolodney, M.S.1    Wysolmerski, R.B.2
  • 116
    • 77951697920 scopus 로고    scopus 로고
    • Regulation of endothelial permeability via paracellular and transcellular transport pathways
    • 10.1146/annurev-physiol-021909-135833 20148685
    • Komarova Y, Malik AB (2010) Regulation of endothelial permeability via paracellular and transcellular transport pathways. Annu Rev Physiol 72:463-93. doi: 10.1146/annurev-physiol-021909-135833
    • (2010) Annu Rev Physiol , vol.72 , pp. 463-493
    • Komarova, Y.1    Malik, A.B.2
  • 117
    • 33846847701 scopus 로고    scopus 로고
    • Rap1: A key regulator in cell-cell junction formation
    • 10.1242/jcs.03306 17182900
    • Kooistra MRH, Dubé N, Bos JL (2007) Rap1: a key regulator in cell-cell junction formation. J Cell Sci 120:17-22. doi: 10.1242/jcs.03306
    • (2007) J Cell Sci , vol.120 , pp. 17-22
    • Kooistra, M.R.H.1    Dubé, N.2    Bos, J.L.3
  • 118
    • 1042268058 scopus 로고    scopus 로고
    • Cdc42 regulates the restoration of endothelial barrier function
    • 10.1161/01.RES.0000110418.38500.31 14656933
    • Kouklis P, Konstantoulaki M, Vogel S, Broman M, Malik AB (2004) Cdc42 regulates the restoration of endothelial barrier function. Circ Res 94:159-66. doi: 10.1161/01.RES.0000110418.38500.31
    • (2004) Circ Res , vol.94 , pp. 159-166
    • Kouklis, P.1    Konstantoulaki, M.2    Vogel, S.3    Broman, M.4    Malik, A.B.5
  • 121
    • 33646179573 scopus 로고    scopus 로고
    • Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics
    • 10.1529/biophysj.105.071506 1440757 16500961
    • Kumar S, Maxwell IZ, Heisterkamp A, Polte TR, Lele TP, Salanga M, Mazur E, Ingber DE (2006) Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics. Biophys J 90:3762-73. doi: 10.1529/biophysj.105.071506
    • (2006) Biophys J , vol.90 , pp. 3762-3773
    • Kumar, S.1    Maxwell, I.Z.2    Heisterkamp, A.3    Polte, T.R.4    Lele, T.P.5    Salanga, M.6    Mazur, E.7    Ingber, D.E.8
  • 123
    • 80051865329 scopus 로고    scopus 로고
    • Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ3
    • doi: 10.1182/blood-2011-04-349282
    • Lakshmikanthan S, Sobczak M, Chun C, Henschel A, Dargatz J, Ramchandran R, Chrzanowska-Wodnicka M (2011) Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ3. Blood 118:2015-26. doi: 10.1182/blood-2011-04-349282
    • (2011) Blood , vol.118 , pp. 2015-2026
    • Lakshmikanthan, S.1    Sobczak, M.2    Chun, C.3    Henschel, A.4    Dargatz, J.5    Ramchandran, R.6    Chrzanowska-Wodnicka, M.7
  • 124
    • 0028900299 scopus 로고
    • The molecular organization of endothelial cell to cell junctions: Differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin)
    • 7698986
    • Lampugnani MG, Corada M, Caveda L, Breviario F, Ayalon O, Geiger B, Dejana E (1995) The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin). J Cell Biol 129:203-17
    • (1995) J Cell Biol , vol.129 , pp. 203-217
    • Lampugnani, M.G.1    Corada, M.2    Caveda, L.3    Breviario, F.4    Ayalon, O.5    Geiger, B.6    Dejana, E.7
  • 126
    • 80053298257 scopus 로고    scopus 로고
    • Mechanotransduction at cadherinmediated adhesions
    • 10.1016/j.ceb.2011.08.003 21890337
    • Leckband DE, le Duc Q, Wang N, de Rooij J (2011) Mechanotransduction at cadherinmediated adhesions. Curr Opin Cell Biol 23:523-30. doi: 10.1016/j.ceb.2011.08.003
    • (2011) Curr Opin Cell Biol , vol.23 , pp. 523-530
    • Leckband, D.E.1    Le Duc, Q.2    Wang, N.3    De Rooij, J.4
  • 127
    • 77956635947 scopus 로고    scopus 로고
    • Clinical implications of basic research Sepsis and Endothelial Permeability
    • 20818861
    • Lee WL, Slutsky AS (2010) clinical implications of basic research Sepsis and Endothelial Permeability. N Engl J Med 363:689-691
    • (2010) N Engl J Med , vol.363 , pp. 689-691
    • Lee, W.L.1    Slutsky, A.S.2
  • 128
    • 84866680424 scopus 로고    scopus 로고
    • From mechanical force to RhoA activation
    • 10.1021/bi300758e 3567302 22931484
    • Lessey EC, Guilluy C, Burridge K (2012) From mechanical force to RhoA activation. Biochemistry 51:7420-32. doi: 10.1021/bi300758e
    • (2012) Biochemistry , vol.51 , pp. 7420-7432
    • Lessey, E.C.1    Guilluy, C.2    Burridge, K.3
  • 130
    • 77955914547 scopus 로고    scopus 로고
    • Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression
    • 10.1083/jcb.201004082 2928007 20733059
    • Liu F, Mih JD, Shea BS, Kho AT, Sharif AS, Tager AM, Tschumperlin DJ (2010) Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression. J Cell Biol 190:693-706. doi: 10.1083/jcb.201004082
    • (2010) J Cell Biol , vol.190 , pp. 693-706
    • Liu, F.1    Mih, J.D.2    Shea, B.S.3    Kho, A.T.4    Sharif, A.S.5    Tager, A.M.6    Tschumperlin, D.J.7
  • 131
    • 84885900541 scopus 로고    scopus 로고
    • Small g proteins in the cardiovascular system: Physiological and pathological aspects
    • 10.1152/physrev.00021.2012 24137019
    • Loirand G, Sauzeau V, Pacaud P (2013) Small g proteins in the cardiovascular system: physiological and pathological aspects. Physiol Rev 93:1659-720. doi: 10.1152/physrev.00021.2012
    • (2013) Physiol Rev , vol.93 , pp. 1659-1720
    • Loirand, G.1    Sauzeau, V.2    Pacaud, P.3
  • 132
    • 58749108112 scopus 로고    scopus 로고
    • Mechanical properties of actin stress fibers in living cells
    • 10.1529/biophysj.108.133462 2599828 18820238
    • Lu L, Oswald SJ, Ngu H, Yin FC-P (2008) Mechanical properties of actin stress fibers in living cells. Biophys J 95:6060-71. doi: 10.1529/biophysj.108. 133462
    • (2008) Biophys J , vol.95 , pp. 6060-6071
    • Lu, L.1    Oswald, S.J.2    Ngu, H.3    Yin, F.-P.4
  • 133
    • 0014577893 scopus 로고
    • Endothelial contraction induced by histaminetype mediators
    • 2107712 5801425
    • Majno G, Shea SM, Leventhal M (1969) Endothelial contraction induced by histaminetype mediators. J Cell Biol 42:647-672
    • (1969) J Cell Biol , vol.42 , pp. 647-672
    • Majno, G.1    Shea, S.M.2    Leventhal, M.3
  • 134
    • 67650504615 scopus 로고    scopus 로고
    • In vivo nanomechanical imaging of blood-vessel tissues directly in living mammals using atomic force microscopy
    • 10.1063/1.3167546
    • Mao Y, Sun Q, Wang X, Ouyang Q, Han L, Jiang L, Han D (2009) In vivo nanomechanical imaging of blood-vessel tissues directly in living mammals using atomic force microscopy. Appl Phys Lett 95:013704. doi: 10.1063/1.3167546
    • (2009) Appl Phys Lett , vol.95 , pp. 013704
    • Mao, Y.1    Sun, Q.2    Wang, X.3    Ouyang, Q.4    Han, L.5    Jiang, L.6    Han, D.7
  • 135
    • 79953214099 scopus 로고    scopus 로고
    • Cell-ECM traction force modulates endogenous tension at cell-cell contacts
    • 10.1073/pnas.1011123108 3064395 21383129
    • Maruthamuthu V, Sabass B, Schwarz US, Gardel ML (2011) Cell-ECM traction force modulates endogenous tension at cell-cell contacts. Proc Natl Acad Sci U S A 108:4708-13. doi: 10.1073/pnas.1011123108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4708-4713
    • Maruthamuthu, V.1    Sabass, B.2    Schwarz, U.S.3    Gardel, M.L.4
  • 136
    • 0036853760 scopus 로고    scopus 로고
    • Local elastic modulus of atherosclerotic lesions of rabbit thoracic aortas measured by pipette aspiration method
    • 12450265
    • Matsumoto T, Abe H, Ohashi T, Kato Y, Sato M (2002) Local elastic modulus of atherosclerotic lesions of rabbit thoracic aortas measured by pipette aspiration method. Physiol Meas 23:635-48
    • (2002) Physiol Meas , vol.23 , pp. 635-648
    • Matsumoto, T.1    Abe, H.2    Ohashi, T.3    Kato, Y.4    Sato, M.5
  • 137
    • 33644839612 scopus 로고    scopus 로고
    • Signaling Mechanisms Regulating Endothelial Permeability
    • 10.1152/physrev.00012.2005 16371600
    • Mehta D, Malik AB (2006) Signaling Mechanisms Regulating Endothelial Permeability. Physiol Rev 86:279-367. doi: 10.1152/physrev.00012.2005
    • (2006) Physiol Rev , vol.86 , pp. 279-367
    • Mehta, D.1    Malik, A.B.2
  • 138
    • 0030270999 scopus 로고    scopus 로고
    • Transport of macromolecules through microvascular walls
    • 8915183
    • Michel CC (1996) Transport of macromolecules through microvascular walls. Cardiovasc Res 32:644-53
    • (1996) Cardiovasc Res , vol.32 , pp. 644-653
    • Michel, C.C.1
  • 141
    • 84879145480 scopus 로고    scopus 로고
    • The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility
    • 10.1371/journal.pone.0066260 3688894 23825001
    • Mitin N, Rossman KL, Currin R, Anne S, Marshall TW, Bear JE, Bautch VL, Der CJ (2013) The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility. PLoS One 8:e66260. doi: 10.1371/journal.pone.0066260
    • (2013) PLoS One , vol.8 , pp. 66260
    • Mitin, N.1    Rossman, K.L.2    Currin, R.3    Anne, S.4    Marshall, T.W.5    Bear, J.E.6    Bautch, V.L.7    Der, C.J.8
  • 142
    • 70350015332 scopus 로고    scopus 로고
    • The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species
    • 10.1074/jbc.M109.009894 2757962 19633358
    • Monaghan-Benson E, Burridge K (2009) The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species. J Biol Chem 284:25602-11. doi: 10.1074/jbc.M109.009894
    • (2009) J Biol Chem , vol.284 , pp. 25602-25611
    • Monaghan-Benson, E.1    Burridge, K.2
  • 143
    • 80054756702 scopus 로고    scopus 로고
    • In vitro analyses of endothelial cell permeability
    • 10.1007/978-1-61779-191-8-19 21874459
    • Monaghan-Benson E, Wittchen ES (2011) In vitro analyses of endothelial cell permeability. Methods Mol Biol 763:281-90. doi: 10.1007/978-1-61779-191-8- 19
    • (2011) Methods Mol Biol , vol.763 , pp. 281-290
    • Monaghan-Benson, E.1    Wittchen, E.S.2
  • 144
    • 0024814233 scopus 로고
    • Pulmonary microvascular endothelial cell contractility on silicone rubber substrate
    • 10.1002/jcp.1041410325 2556412
    • Morel NM, Dodge AB, Patton WF, Herman IM, Hechtman HB, Shepro D (1989) Pulmonary microvascular endothelial cell contractility on silicone rubber substrate. J Cell Physiol 141:653-9. doi: 10.1002/jcp.1041410325
    • (1989) J Cell Physiol , vol.141 , pp. 653-659
    • Morel, N.M.1    Dodge, A.B.2    Patton, W.F.3    Herman, I.M.4    Hechtman, H.B.5    Shepro, D.6
  • 145
    • 84871544837 scopus 로고    scopus 로고
    • A critical role for phosphatidylinositol (3,4,5)-trisphosphate-dependent Rac exchanger 1 in endothelial junction disruption and vascular hyperpermeability
    • 10.1161/CIRCRESAHA.112.273078 3677960 22965143
    • Naikawadi RP, Cheng N, Vogel SM, Qian F, Wu D, Malik AB, Ye RD (2012) A critical role for phosphatidylinositol (3,4,5)-trisphosphate-dependent Rac exchanger 1 in endothelial junction disruption and vascular hyperpermeability. Circ Res 111:1517-27. doi: 10.1161/CIRCRESAHA.112.273078
    • (2012) Circ Res , vol.111 , pp. 1517-1527
    • Naikawadi, R.P.1    Cheng, N.2    Vogel, S.M.3    Qian, F.4    Wu, D.5    Malik, A.B.6    Ye, R.D.7
  • 146
    • 84871882564 scopus 로고    scopus 로고
    • Facio-genital dysplasia-5 regulates matrix adhesion and survival of human endothelial cells
    • 10.1161/ATVBAHA.112.300074 22922960
    • Nakhaei-Nejad M, Haddad G, Zhang Q-X, Murray AG (2012) Facio-genital dysplasia-5 regulates matrix adhesion and survival of human endothelial cells. Arterioscler Thromb Vasc Biol 32:2694-701. doi: 10.1161/ATVBAHA.112.300074
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 2694-2701
    • Nakhaei-Nejad, M.1    Haddad, G.2    Zhang, Q.-X.3    Murray, A.G.4
  • 147
    • 0030612748 scopus 로고    scopus 로고
    • Rho effectors and reorganization of actin cytoskeleton
    • 10.1016/S0014-5793(97)00317-7 9247125
    • Narumiya S, Ishizaki T, Watanabe N (1997) Rho effectors and reorganization of actin cytoskeleton. FEBS Lett 410:68-72. doi: 10.1016/S0014-5793(97)00317-7
    • (1997) FEBS Lett , vol.410 , pp. 68-72
    • Narumiya, S.1    Ishizaki, T.2    Watanabe, N.3
  • 148
    • 84883350938 scopus 로고    scopus 로고
    • TEM4 is a junctional Rho GEF required for cell-cell adhesion, monolayer integrity and barrier function
    • 10.1242/jcs.123869 23729734
    • Ngok SP, Geyer R, Kourtidis A, Mitin N, Feathers R, Der C, Anastasiadis PZ (2013) TEM4 is a junctional Rho GEF required for cell-cell adhesion, monolayer integrity and barrier function. J Cell Sci 126:3271-7. doi: 10.1242/jcs.123869
    • (2013) J Cell Sci , vol.126 , pp. 3271-3277
    • Ngok, S.P.1    Geyer, R.2    Kourtidis, A.3    Mitin, N.4    Feathers, R.5    Der, C.6    Anastasiadis, P.Z.7
  • 149
    • 0035823593 scopus 로고    scopus 로고
    • Cadherin engagement regulates Rho family GTPases
    • 10.1074/jbc.C100306200 11457821
    • Noren NK, Niessen CM, Gumbiner BM, Burridge K (2001) Cadherin engagement regulates Rho family GTPases. J Biol Chem 276:33305-8. doi: 10.1074/jbc. C100306200
    • (2001) J Biol Chem , vol.276 , pp. 33305-33308
    • Noren, N.K.1    Niessen, C.M.2    Gumbiner, B.M.3    Burridge, K.4
  • 150
    • 84868352478 scopus 로고    scopus 로고
    • RhoA localization with caveolin-1 regulates vascular contractions to serotonin
    • 10.1152/ajpregu.00667.2011 3517699 22955057
    • Nuno DW, England SK, Lamping KG (2012) RhoA localization with caveolin-1 regulates vascular contractions to serotonin. Am J Physiol Regul Integr Comp Physiol 303:R959-67. doi: 10.1152/ajpregu.00667.2011
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.303 , pp. 959-967
    • Nuno, D.W.1    England, S.K.2    Lamping, K.G.3
  • 151
    • 80052307379 scopus 로고    scopus 로고
    • Is arterial wall-strain stiffening an additional process responsible for atherosclerosis in coronary bifurcations?: An in vivo study based on dynamic CT and MRI
    • 10.1152/ajpheart.01120.2010 3191077 21685261
    • Ohayon J, Gharib AM, Garcia A, Heroux J, Yazdani SK, Malvè M, Tracqui P, Martinez M-A, Doblare M, Finet G, Pettigrew RI (2011) Is arterial wall-strain stiffening an additional process responsible for atherosclerosis in coronary bifurcations?: an in vivo study based on dynamic CT and MRI. Am J Physiol Heart Circ Physiol 301:H1097-106. doi: 10.1152/ajpheart.01120.2010
    • (2011) Am J Physiol Heart Circ Physiol , vol.301 , pp. 1097-1106
    • Ohayon, J.1    Gharib, A.M.2    Garcia, A.3    Heroux, J.4    Yazdani, S.K.5    Malvè, M.6    Tracqui, P.7    Martinez, M.-A.8    Doblare, M.9    Finet, G.10    Pettigrew, R.I.11
  • 152
    • 0033058184 scopus 로고    scopus 로고
    • Rho guanine dissociation inhibitors: Pivotal molecules in cellular signalling
    • 10433515
    • Olofsson B (1999) Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling. Cell Signal 11:545-54
    • (1999) Cell Signal , vol.11 , pp. 545-554
    • Olofsson, B.1
  • 153
    • 29744458411 scopus 로고    scopus 로고
    • Mechanisms of mechanotransduction
    • 10.1016/j.devcel.2005.12.006 16399074
    • Orr AW, Helmke BP, Blackman BR, Schwartz MA (2006) Mechanisms of mechanotransduction. Dev Cell 10:11-20. doi: 10.1016/j.devcel.2005.12.006
    • (2006) Dev Cell , vol.10 , pp. 11-20
    • Orr, A.W.1    Helmke, B.P.2    Blackman, B.R.3    Schwartz, M.A.4
  • 154
    • 84874566916 scopus 로고    scopus 로고
    • Rap1 and Rap2 antagonistically control endothelial barrier resistance
    • 10.1371/journal.pone.0057903 3585282 23469100
    • Pannekoek W-J, Linnemann JR, Brouwer PM, Bos JL, Rehmann H (2013) Rap1 and Rap2 antagonistically control endothelial barrier resistance. PLoS One 8:e57903. doi: 10.1371/journal.pone.0057903
    • (2013) PLoS One , vol.8 , pp. 57903
    • Pannekoek, W.-J.1    Linnemann, J.R.2    Brouwer, P.M.3    Bos, J.L.4    Rehmann, H.5
  • 155
    • 21444443229 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha stimulation of Rac1 activity. Role of isoprenylcysteine carboxylmethyltransferase
    • 10.1074/jbc.M410081200 15647276
    • Papaharalambus C, Sajjad W, Syed A, Zhang C, Bergo MO, Alexander RW, Ahmad M (2005) Tumor necrosis factor alpha stimulation of Rac1 activity. Role of isoprenylcysteine carboxylmethyltransferase. J Biol Chem 280:18790-6. doi: 10.1074/jbc.M410081200
    • (2005) J Biol Chem , vol.280 , pp. 18790-18796
    • Papaharalambus, C.1    Sajjad, W.2    Syed, A.3    Zhang, C.4    Bergo, M.O.5    Alexander, R.W.6    Ahmad, M.7
  • 156
    • 0344912596 scopus 로고    scopus 로고
    • Cell locomotion and focal adhesions are regulated by substrate flexibility
    • 28362 9391082
    • Pelham RJ, Wang YI (1997) Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc Natl Acad Sci U S A 94:13661-5
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13661-13665
    • Pelham, R.J.1    Wang, Y.I.2
  • 157
    • 77953145912 scopus 로고    scopus 로고
    • Spatio-temporal Rho GTPase signaling - Where are we now?
    • 10.1242/jcs.064345 20484664
    • Pertz O (2010) Spatio-temporal Rho GTPase signaling - where are we now? J Cell Sci 123:1841-50. doi: 10.1242/jcs.064345
    • (2010) J Cell Sci , vol.123 , pp. 1841-1850
    • Pertz, O.1
  • 158
    • 34548311599 scopus 로고    scopus 로고
    • The emergence of ECM mechanics and cytoskeletal tension as important regulators of cell function
    • 10.1007/s12013-007-0004-y 17652777
    • Peyton SR, Ghajar CM, Khatiwala CB, Putnam AJ (2007) The emergence of ECM mechanics and cytoskeletal tension as important regulators of cell function. Cell Biochem Biophys 47:300-320. doi: 10.1007/s12013-007-0004-y
    • (2007) Cell Biochem Biophys , vol.47 , pp. 300-320
    • Peyton, S.R.1    Ghajar, C.M.2    Khatiwala, C.B.3    Putnam, A.J.4
  • 159
    • 84882865773 scopus 로고    scopus 로고
    • Guiding cell migration by tugging
    • 10.1016/j.ceb.2013.06.003 23830911
    • Plotnikov SVV, Waterman CM (2013) Guiding cell migration by tugging. Curr Opin Cell Biol 25:619-26. doi: 10.1016/j.ceb.2013.06.003
    • (2013) Curr Opin Cell Biol , vol.25 , pp. 619-626
    • Plotnikov, S.V.V.1    Waterman, C.M.2
  • 160
    • 84871591464 scopus 로고    scopus 로고
    • Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration
    • 10.1016/j.cell.2012.11.034 23260139
    • Plotnikov SVV, Pasapera AM, Sabass B, Waterman CM (2012) Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration. Cell 151:1513-27. doi: 10.1016/j.cell.2012.11.034
    • (2012) Cell , vol.151 , pp. 1513-1527
    • Plotnikov, S.V.V.1    Pasapera, A.M.2    Sabass, B.3    Waterman, C.M.4
  • 161
    • 84878709987 scopus 로고    scopus 로고
    • RhoA is down-regulated at cell-cell contacts via p190RhoGAP-B in response to tensional homeostasis
    • 10.1091/mbc.E12-05-0386
    • Ponik SM, Trier SM, Wozniak MA, Eliceiri KW, Keely PJ (2013) RhoA is down-regulated at cell-cell contacts via p190RhoGAP-B in response to tensional homeostasis. Mol Biol Cell 24(1688-99):S1-3. doi: 10.1091/mbc.E12-05-0386
    • (2013) Mol Biol Cell , vol.24 , Issue.99-1688 , pp. 1-3
    • Ponik, S.M.1    Trier, S.M.2    Wozniak, M.A.3    Eliceiri, K.W.4    Keely, P.J.5
  • 162
    • 63249127139 scopus 로고    scopus 로고
    • Multifaceted role of Rho, Rac, Cdc42 and Ras in intercellular junctions, lessons from toxins
    • 10.1016/j.bbamem.2009.01.011 19366594
    • Popoff MR, Geny B (2009) Multifaceted role of Rho, Rac, Cdc42 and Ras in intercellular junctions, lessons from toxins. Biochim Biophys Acta 1788:797-812. doi: 10.1016/j.bbamem.2009.01.011
    • (2009) Biochim Biophys Acta , vol.1788 , pp. 797-812
    • Popoff, M.R.1    Geny, B.2
  • 163
    • 84879993509 scopus 로고    scopus 로고
    • Rasip1 mediates Rap1 regulation of Rho in endothelial barrier function through ArhGAP29
    • 10.1073/pnas.1306595110 3710801 23798437
    • Post A, Pannekoek W-J, Ross SH, Verlaan I, Brouwer PM, Bos JL (2013) Rasip1 mediates Rap1 regulation of Rho in endothelial barrier function through ArhGAP29. Proc Natl Acad Sci U S A 110:11427-32. doi: 10.1073/pnas.1306595110
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 11427-11432
    • Post, A.1    Pannekoek, W.-J.2    Ross, S.H.3    Verlaan, I.4    Brouwer, P.M.5    Bos, J.L.6
  • 164
    • 0038172667 scopus 로고    scopus 로고
    • PKA inhibits RhoA activation: A protection mechanism against endothelial barrier dysfunction
    • 10.1152/ajplung.00429.2002 12588708
    • Qiao J, Huang F, Lum H (2003) PKA inhibits RhoA activation: a protection mechanism against endothelial barrier dysfunction. Am J Physiol Lung Cell Mol Physiol 284:L972-80. doi: 10.1152/ajplung.00429.2002
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284 , pp. 972-980
    • Qiao, J.1    Huang, F.2    Lum, H.3
  • 165
    • 57349199406 scopus 로고    scopus 로고
    • Phosphorylation of GTP dissociation inhibitor by PKA negatively regulates RhoA
    • 10.1152/ajpcell.00139.2008 2584978 18768928
    • Qiao J, Holian O, Lee B-S, Huang F, Zhang J, Lum H (2008) Phosphorylation of GTP dissociation inhibitor by PKA negatively regulates RhoA. Am J Physiol Cell Physiol 295:C1161-8. doi: 10.1152/ajpcell.00139.2008
    • (2008) Am J Physiol Cell Physiol , vol.295 , pp. 1161-1168
    • Qiao, J.1    Holian, O.2    Lee, B.-S.3    Huang, F.4    Zhang, J.5    Lum, H.6
  • 166
    • 26844512182 scopus 로고    scopus 로고
    • Age- and gender-related ventricular-vascular stiffening: A community-based study
    • 10.1161/CIRCULATIONAHA.105.541078 16203909
    • Redfield MM, Jacobsen SJ, Borlaug BA, Rodeheffer RJ, Kass DA (2005) Age- and gender-related ventricular-vascular stiffening: a community-based study. Circulation 112:2254-62. doi: 10.1161/CIRCULATIONAHA.105.541078
    • (2005) Circulation , vol.112 , pp. 2254-2262
    • Redfield, M.M.1    Jacobsen, S.J.2    Borlaug, B.A.3    Rodeheffer, R.J.4    Kass, D.A.5
  • 167
    • 23244464968 scopus 로고    scopus 로고
    • The dynamics and mechanics of endothelial cell spreading
    • 10.1529/biophysj.104.054320 1366566 15849250
    • Reinhart-King CA, Dembo M, Hammer DA (2005) The dynamics and mechanics of endothelial cell spreading. Biophys J 89:676-89. doi: 10.1529/biophysj.104. 054320
    • (2005) Biophys J , vol.89 , pp. 676-689
    • Reinhart-King, C.A.1    Dembo, M.2    Hammer, D.A.3
  • 168
    • 33748994545 scopus 로고    scopus 로고
    • Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking
    • 10.1016/j.tcb.2006.08.006 16949823
    • Ridley AJ (2006) Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends Cell Biol 16:522-9. doi: 10.1016/j.tcb.2006.08. 006
    • (2006) Trends Cell Biol , vol.16 , pp. 522-529
    • Ridley, A.J.1
  • 169
    • 0026778133 scopus 로고
    • The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
    • 1643657
    • Ridley AJ, Hall A (1992) The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70:389-99
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 170
    • 70349496205 scopus 로고    scopus 로고
    • Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction
    • 10.1073/pnas.0902818106 2752568 19805288
    • Roca-Cusachs P, Gauthier NC, Del Rio A, Sheetz MP (2009) Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction. Proc Natl Acad Sci U S A 106:16245-50. doi: 10.1073/pnas.0902818106
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 16245-16250
    • Roca-Cusachs, P.1    Gauthier, N.C.2    Del Rio, A.3    Sheetz, M.P.4
  • 171
    • 84859967413 scopus 로고    scopus 로고
    • The Ras protein superfamily: Evolutionary tree and role of conserved amino acids
    • 10.1083/jcb.201103008 3265948 22270915
    • Rojas AM, Fuentes G, Rausell A, Valencia A (2012) The Ras protein superfamily: evolutionary tree and role of conserved amino acids. J Cell Biol 196:189-201. doi: 10.1083/jcb.201103008
    • (2012) J Cell Biol , vol.196 , pp. 189-201
    • Rojas, A.M.1    Fuentes, G.2    Rausell, A.3    Valencia, A.4
  • 174
    • 13444252631 scopus 로고    scopus 로고
    • GEF means go: Turning on RHO GTPases with guanine nucleotide-exchange factors
    • 10.1038/nrm1587 15688002
    • Rossman KL, Der CJ, Sondek J (2005) GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol 6:167-80. doi: 10.1038/nrm1587
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 167-180
    • Rossman, K.L.1    Der, C.J.2    Sondek, J.3
  • 175
    • 28444491145 scopus 로고    scopus 로고
    • Is the mechanical activity of epithelial cells controlled by deformations or forces?
    • 10.1529/biophysj.105.071217 1367004 16214867
    • Saez A, Buguin A, Silberzan P, Ladoux B (2005) Is the mechanical activity of epithelial cells controlled by deformations or forces? Biophys J 89:L52-4. doi: 10.1529/biophysj.105.071217
    • (2005) Biophys J , vol.89 , pp. 52-54
    • Saez, A.1    Buguin, A.2    Silberzan, P.3    Ladoux, B.4
  • 176
    • 0037131313 scopus 로고    scopus 로고
    • Microvascular hyperpermeability in caveolin-1(-/-) knock-out mice. Treatment with a specific nitric-oxide synthase inhibitor, L-NAME, restores normal microvascular permeability in Cav-1 null mice
    • doi: 10.1074/jbc.M205948200
    • Schubert W, Frank PG, Woodman SE, Hyogo H, Cohen DE, Chow C-W, Lisanti MP (2002) Microvascular hyperpermeability in caveolin-1(-/-) knock-out mice. Treatment with a specific nitric-oxide synthase inhibitor, L-NAME, restores normal microvascular permeability in Cav-1 null mice. J Biol Chem 277:40091-8. doi: 10.1074/jbc.M205948200
    • (2002) J Biol Chem , vol.277 , pp. 40091-40098
    • Schubert, W.1    Frank, P.G.2    Woodman, S.E.3    Hyogo, H.4    Cohen, D.E.5    Chow, C.-W.6    Lisanti, M.P.7
  • 177
    • 79952598024 scopus 로고    scopus 로고
    • Integrins and extracellular matrix in mechanotransduction
    • 10.1101/cshperspect.a005066 2982167 21084386
    • Schwartz MA (2010) Integrins and extracellular matrix in mechanotransduction. Cold Spring Harb Perspect Biol 2:a005066. doi: 10.1101/cshperspect.a005066
    • (2010) Cold Spring Harb Perspect Biol , vol.2 , pp. 005066
    • Schwartz, M.A.1
  • 178
    • 50849083158 scopus 로고    scopus 로고
    • Cell adhesion receptors in mechanotransduction
    • 10.1016/j.ceb.2008.05.005 2581799 18583124
    • Schwartz MA, DeSimone DW (2008) Cell adhesion receptors in mechanotransduction. Curr Opin Cell Biol 20:551-6. doi: 10.1016/j.ceb.2008.05. 005
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 551-556
    • Schwartz, M.A.1    Desimone, D.W.2
  • 179
    • 84873834447 scopus 로고    scopus 로고
    • Caveolin-1 regulates Rac1 activation and rat pulmonary microvascular endothelial hyperpermeability induced by TNF-α
    • 10.1371/journal.pone.0055213 3559378 23383114
    • Shao M, Yue Y, Sun G-Y, You Q-H, Wang N, Zhang D (2013) Caveolin-1 regulates Rac1 activation and rat pulmonary microvascular endothelial hyperpermeability induced by TNF-α. PLoS One 8:e55213. doi: 10.1371/journal.pone.0055213
    • (2013) PLoS One , vol.8 , pp. 55213
    • Shao, M.1    Yue, Y.2    Sun, G.-Y.3    You, Q.-H.4    Wang, N.5    Zhang, D.6
  • 180
    • 65249182654 scopus 로고    scopus 로고
    • The Role of FilGAPFilamin A Interactions in Mechanoprotection
    • 10.1091/mbc.E08 2649276 19144823
    • Shifrin Y, Arora PD, Ohta Y, Calderwood DA, Mcculloch CA (2009) The Role of FilGAPFilamin A Interactions in Mechanoprotection. Mol Biol Cell 20:1269-1279. doi: 10.1091/mbc.E08
    • (2009) Mol Biol Cell , vol.20 , pp. 1269-1279
    • Shifrin, Y.1    Arora, P.D.2    Ohta, Y.3    Calderwood, D.A.4    McCulloch, C.A.5
  • 181
    • 13544264582 scopus 로고    scopus 로고
    • Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells
    • 10.1016/j.yexcr.2004.11.001 15707572
    • Shikata Y, Rios A, Kawkitinarong K, DePaola N, Garcia JGN, Birukov KG (2005) Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells. Exp Cell Res 304:40-9. doi: 10.1016/j.yexcr.2004.11.001
    • (2005) Exp Cell Res , vol.304 , pp. 40-49
    • Shikata, Y.1    Rios, A.2    Kawkitinarong, K.3    Depaola, N.4    Garcia, J.G.N.5    Birukov, K.G.6
  • 182
    • 1942519286 scopus 로고    scopus 로고
    • Rho mediates the shear-enhancement of endothelial cell migration and traction force generation
    • 10.1016/S0006-3495(04)74311-8 1304103 15041692
    • Shiu Y-T, Li S, Marganski WA, Usami S, Schwartz MA, Wang Y-L, Dembo M, Chien S (2004) Rho mediates the shear-enhancement of endothelial cell migration and traction force generation. Biophys J 86:2558-65. doi: 10.1016/S0006-3495(04) 74311-8
    • (2004) Biophys J , vol.86 , pp. 2558-2565
    • Shiu, Y.-T.1    Li, S.2    Marganski, W.A.3    Usami, S.4    Schwartz, M.A.5    Wang, Y.-L.6    Dembo, M.7    Chien, S.8
  • 184
    • 18444406288 scopus 로고    scopus 로고
    • Rho-GTPases: New members, new pathways
    • 10.1002/jcb.20327 15543593
    • Sorokina EM, Chernoff J (2005) Rho-GTPases: new members, new pathways. J Cell Biochem 94:225-31. doi: 10.1002/jcb.20327
    • (2005) J Cell Biochem , vol.94 , pp. 225-231
    • Sorokina, E.M.1    Chernoff, J.2
  • 185
    • 77954334673 scopus 로고    scopus 로고
    • Role of GTPases in control of microvascular permeability
    • 10.1093/cvr/cvq086 20299335
    • Spindler V, Schlegel N, Waschke J (2010) Role of GTPases in control of microvascular permeability. Cardiovasc Res 87:243-53. doi: 10.1093/cvr/cvq086
    • (2010) Cardiovasc Res , vol.87 , pp. 243-253
    • Spindler, V.1    Schlegel, N.2    Waschke, J.3
  • 186
    • 84866292915 scopus 로고    scopus 로고
    • Relocalization of junctional adhesion molecule A during inflammatory stimulation of brain endothelial cells
    • 10.1128/MCB.06678-11 3422009 22733993
    • Stamatovic SM, Sladojevic N, Keep RF, Andjelkovic AV (2012) Relocalization of junctional adhesion molecule A during inflammatory stimulation of brain endothelial cells. Mol Cell Biol 32:3414-27. doi: 10.1128/MCB.06678-11
    • (2012) Mol Cell Biol , vol.32 , pp. 3414-3427
    • Stamatovic, S.M.1    Sladojevic, N.2    Keep, R.F.3    Andjelkovic, A.V.4
  • 187
    • 84875373173 scopus 로고    scopus 로고
    • Rho GTPases in pulmonary vascular dysfunction
    • 10.1016/j.vph.2012.09.004 22982942
    • Storck EM, Wojciak-Stothard B (2013) Rho GTPases in pulmonary vascular dysfunction. Vascul Pharmacol 58:202-10. doi: 10.1016/j.vph.2012.09.004
    • (2013) Vascul Pharmacol , vol.58 , pp. 202-210
    • Storck, E.M.1    Wojciak-Stothard, B.2
  • 188
    • 79960325552 scopus 로고    scopus 로고
    • Spatiotemporal constraints on the force-dependent growth of focal adhesions
    • 10.1016/j.bpj.2011.05.023 3123981 21689521
    • Stricker J, Aratyn-Schaus Y, Oakes PW, Gardel ML (2011) Spatiotemporal constraints on the force-dependent growth of focal adhesions. Biophys J 100:2883-93. doi: 10.1016/j.bpj.2011.05.023
    • (2011) Biophys J , vol.100 , pp. 2883-2893
    • Stricker, J.1    Aratyn-Schaus, Y.2    Oakes, P.W.3    Gardel, M.L.4
  • 189
    • 79952626846 scopus 로고    scopus 로고
    • Effects of Morphology vs. Cell-Cell Interactions on Endothelial Cell Stiffness
    • 10.1007/s12195-010-0142-y 3044329 21359128
    • Stroka KM, Aranda-Espinoza H (2011) Effects of Morphology vs. Cell-Cell Interactions on Endothelial Cell Stiffness. Cell Mol Bioeng 4:9-27. doi: 10.1007/s12195-010-0142-y
    • (2011) Cell Mol Bioeng , vol.4 , pp. 9-27
    • Stroka, K.M.1    Aranda-Espinoza, H.2
  • 190
    • 79952626846 scopus 로고    scopus 로고
    • Effects of Morphology vs. Cell-Cell Interactions on Endothelial Cell Stiffness
    • 10.1007/s12195-010-0142-y.Effects
    • Stroka KM, Aranda-Espinoza H (2012) Effects of Morphology vs. Cell-Cell Interactions on Endothelial Cell Stiffness. Cell Mol Bioeng 4:9-27. doi: 10.1007/s12195-010-0142-y.Effects
    • (2012) Cell Mol Bioeng , vol.4 , pp. 9-27
    • Stroka, K.M.1    Aranda-Espinoza, H.2
  • 192
    • 0033611107 scopus 로고    scopus 로고
    • Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2
    • 2174243 10613909
    • Sumi T, Matsumoto K, Takai Y, Nakamura T (1999) Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2. J Cell Biol 147:1519-32
    • (1999) J Cell Biol , vol.147 , pp. 1519-1532
    • Sumi, T.1    Matsumoto, K.2    Takai, Y.3    Nakamura, T.4
  • 194
    • 84892520318 scopus 로고    scopus 로고
    • ARP2/3-mediated junctionassociated lamellipodia control VE-cadherin-based cell junction dynamics and maintain monolayer integrity
    • 10.1091/mbc.E13-07-0404 3890345 24227887
    • Taha AA, Taha M, Seebach J, Schnittler H-J (2014) ARP2/3-mediated junctionassociated lamellipodia control VE-cadherin-based cell junction dynamics and maintain monolayer integrity. Mol Biol Cell 25:245-56. doi: 10.1091/mbc.E13-07-0404
    • (2014) Mol Biol Cell , vol.25 , pp. 245-256
    • Taha, A.A.1    Taha, M.2    Seebach, J.3    Schnittler, H.-J.4
  • 196
    • 84874543570 scopus 로고    scopus 로고
    • Monolayer stress microscopy: Limitations, artifacts, and accuracy of recovered intercellular stresses
    • 10.1371/journal.pone.0055172 3585344 23468843
    • Tambe DT, Croutelle U, Trepat X, Park CY, Kim JH, Millet E, Butler JP, Fredberg JJ (2013) Monolayer stress microscopy: limitations, artifacts, and accuracy of recovered intercellular stresses. PLoS One 8:e55172. doi: 10.1371/journal.pone.0055172
    • (2013) PLoS One , vol.8 , pp. 55172
    • Tambe, D.T.1    Croutelle, U.2    Trepat, X.3    Park, C.Y.4    Kim, J.H.5    Millet, E.6    Butler, J.P.7    Fredberg, J.J.8
  • 197
    • 44949179828 scopus 로고    scopus 로고
    • An essential role for Rac1 in endothelial cell function and vascular development
    • 10.1096/fj.07-096438 18245172
    • Tan W, Palmby TR, Gavard J, Amornphimoltham P, Zheng Y, Gutkind JS (2008) An essential role for Rac1 in endothelial cell function and vascular development. FASEB J 22:1829-38. doi: 10.1096/fj.07-096438
    • (2008) FASEB J , vol.22 , pp. 1829-1838
    • Tan, W.1    Palmby, T.R.2    Gavard, J.3    Amornphimoltham, P.4    Zheng, Y.5    Gutkind, J.S.6
  • 198
    • 0031042493 scopus 로고    scopus 로고
    • Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton
    • Tapon N, Hall A (1997) Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton. Curr Opin Cell Biol 86-92
    • (1997) Curr Opin Cell Biol , pp. 86-92
    • Tapon, N.1    Hall, A.2
  • 199
    • 33846969965 scopus 로고    scopus 로고
    • Current knowledge of the large RhoGAP family of proteins
    • 10.1042/BC20060086 17222083
    • Tcherkezian J, Lamarche-Vane N (2007) Current knowledge of the large RhoGAP family of proteins. Biol Cell 99:67-86. doi: 10.1042/BC20060086
    • (2007) Biol Cell , vol.99 , pp. 67-86
    • Tcherkezian, J.1    Lamarche-Vane, N.2
  • 200
    • 76349098227 scopus 로고    scopus 로고
    • Rho signaling and tight junction functions
    • 10.1152/physiol.00034.2009 20134025
    • Terry S, Nie M, Matter K, Balda MS (2010) Rho signaling and tight junction functions. Physiology 25:16-26. doi: 10.1152/physiol.00034.2009
    • (2010) Physiology , vol.25 , pp. 16-26
    • Terry, S.1    Nie, M.2    Matter, K.3    Balda, M.S.4
  • 201
    • 84888437392 scopus 로고    scopus 로고
    • Physiological roles of Rho and Rho effectors in mammals
    • 10.1016/j.ejcb.2013.09.002 24183240
    • Thumkeo D, Watanabe S, Narumiya S (2013) Physiological roles of Rho and Rho effectors in mammals. Eur J Cell Biol 92:303-15. doi: 10.1016/j.ejcb.2013. 09.002
    • (2013) Eur J Cell Biol , vol.92 , pp. 303-315
    • Thumkeo, D.1    Watanabe, S.2    Narumiya, S.3
  • 202
    • 84894483331 scopus 로고    scopus 로고
    • Control of vascular permeability by atrial natriuretic peptide via GEF-H1-dependent mechanism
    • 10.1074/jbc.M113.493924
    • Tian X, Tian Y, Gawlak G, Sarich N, Wu T, Birukova AA (2013) Control of vascular permeability by atrial natriuretic peptide via GEF-H1-dependent mechanism. J Biol Chem. doi: 10.1074/jbc.M113.493924
    • (2013) J Biol Chem
    • Tian, X.1    Tian, Y.2    Gawlak, G.3    Sarich, N.4    Wu, T.5    Birukova, A.A.6
  • 203
    • 33644866797 scopus 로고    scopus 로고
    • Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response
    • 10.1161/01.RES.0000200162.94463.d7 16456110
    • Tzima E (2006) Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response. Circ Res 98:176-85. doi: 10.1161/01.RES. 0000200162.94463.d7
    • (2006) Circ Res , vol.98 , pp. 176-185
    • Tzima, E.1
  • 204
    • 0032583083 scopus 로고    scopus 로고
    • Transient and Prolonged Increase in Endothelial Permeability Induced by Histamine and Thrombin: Role of Protein Kinases, Calcium, and RhoA
    • 10.1161/01.RES.83.11.1115 9831706
    • Van Nieuw Amerongen GP, Draijer R, Vermeer MA, van Hinsbergh VWM (1998) Transient and Prolonged Increase in Endothelial Permeability Induced by Histamine and Thrombin: Role of Protein Kinases, Calcium, and RhoA. Circ Res 83:1115-1123. doi: 10.1161/01.RES.83.11.1115
    • (1998) Circ Res , vol.83 , pp. 1115-1123
    • Van Nieuw Amerongen, G.P.1    Draijer, R.2    Vermeer, M.A.3    Van Hinsbergh, V.W.M.4
  • 205
    • 0034682993 scopus 로고    scopus 로고
    • Activation of RhoA by Thrombin in Endothelial Hyperpermeability: Role of Rho Kinase and Protein Tyrosine Kinases
    • 10.1161/01.RES.87.4.335 10948069
    • Van Nieuw Amerongen GP, Van Delft S, Vermeer MA, Collard JG, van Hinsbergh VWM (2000) Activation of RhoA by Thrombin in Endothelial Hyperpermeability: Role of Rho Kinase and Protein Tyrosine Kinases. Circ Res 87:335-340. doi: 10.1161/01.RES.87.4.335
    • (2000) Circ Res , vol.87 , pp. 335-340
    • Van Nieuw Amerongen, G.P.1    Van Delft, S.2    Vermeer, M.A.3    Collard, J.G.4    Van Hinsbergh, V.W.M.5
  • 206
    • 0037324359 scopus 로고    scopus 로고
    • Involvement of RhoA/Rho Kinase Signaling in VEGF-Induced Endothelial Cell Migration and Angiogenesis in Vitro
    • 10.1161/01.ATV.0000054198.68894.88 12588761
    • Van Nieuw Amerongen GP, Koolwijk P, Versteilen AMG, van Hinsbergh VWM (2003) Involvement of RhoA/Rho Kinase Signaling in VEGF-Induced Endothelial Cell Migration and Angiogenesis In Vitro. Arterioscler Thromb Vasc Biol 23:211-217. doi: 10.1161/01.ATV.0000054198.68894.88
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 211-217
    • Van Nieuw Amerongen, G.P.1    Koolwijk, P.2    Versteilen, A.M.G.3    Van Hinsbergh, V.W.M.4
  • 207
    • 41149164199 scopus 로고    scopus 로고
    • Regulation of endothelial junctional permeability
    • 10.1196/annals.1420.016 18375586
    • Vandenbroucke E, Mehta D, Minshall R, Malik AB (2008) Regulation of endothelial junctional permeability. Ann N Y Acad Sci 1123:134-45. doi: 10.1196/annals.1420.016
    • (2008) Ann N y Acad Sci , vol.1123 , pp. 134-145
    • Vandenbroucke, E.1    Mehta, D.2    Minshall, R.3    Malik, A.B.4
  • 208
    • 48249113787 scopus 로고    scopus 로고
    • A novel mechanism of TGFbeta-induced actin reorganization mediated by Smad proteins and Rho GTPases
    • 10.1111/j.1742-4658.2008.06549.x 18631173
    • Vardouli L, Vasilaki E, Papadimitriou E, Kardassis D, Stournaras C (2008) A novel mechanism of TGFbeta-induced actin reorganization mediated by Smad proteins and Rho GTPases. FEBS J 275:4074-87. doi: 10.1111/j.1742-4658.2008. 06549.x
    • (2008) FEBS J , vol.275 , pp. 4074-4087
    • Vardouli, L.1    Vasilaki, E.2    Papadimitriou, E.3    Kardassis, D.4    Stournaras, C.5
  • 209
    • 0032209748 scopus 로고    scopus 로고
    • Biochemical regulation of the nonmuscle myosin light chain kinase isoform in bovine endothelium
    • 10.1165/ajrcmb.19.5.3126 9806741
    • Verin AD, Gilbert-McClain LI, Patterson CE, Garcia JGN (1998) Biochemical regulation of the nonmuscle myosin light chain kinase isoform in bovine endothelium. Am J Respir Cell Mol Biol 19:767-76. doi: 10.1165/ajrcmb.19.5.3126
    • (1998) Am J Respir Cell Mol Biol , vol.19 , pp. 767-776
    • Verin, A.D.1    Gilbert-Mcclain, L.I.2    Patterson, C.E.3    Garcia, J.G.N.4
  • 210
    • 58149492762 scopus 로고    scopus 로고
    • Cell adhesion dynamics at endothelial junctions: VE-cadherin as a major player
    • 10.1016/j.tcb.2008.10.001 19010680
    • Vestweber D, Winderlich M, Cagna G, Nottebaum AF (2009) Cell adhesion dynamics at endothelial junctions: VE-cadherin as a major player. Trends Cell Biol 19:8-15. doi: 10.1016/j.tcb.2008.10.001
    • (2009) Trends Cell Biol , vol.19 , pp. 8-15
    • Vestweber, D.1    Winderlich, M.2    Cagna, G.3    Nottebaum, A.F.4
  • 211
    • 0031717365 scopus 로고    scopus 로고
    • Regulation of the actin cytoskeleton by thrombin in human endothelial cells: Role of Rho proteins in endothelial barrier function
    • 25537 9725917
    • Vouret-Craviari V, Boquet P, Pouysségur J, Van Obberghen-Schilling E (1998) Regulation of the actin cytoskeleton by thrombin in human endothelial cells: role of Rho proteins in endothelial barrier function. Mol Biol Cell 9:2639-53
    • (1998) Mol Biol Cell , vol.9 , pp. 2639-2653
    • Vouret-Craviari, V.1    Boquet, P.2    Pouysségur, J.3    Van Obberghen-Schilling, E.4
  • 212
    • 39849104321 scopus 로고    scopus 로고
    • Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis
    • 10.1016/j.bbamem.2007.09.003 17961505
    • Wallez Y, Huber P (2008) Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis. Biochim Biophys Acta 1778:794-809. doi: 10.1016/j.bbamem.2007.09.003
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 794-809
    • Wallez, Y.1    Huber, P.2
  • 213
    • 4444239782 scopus 로고    scopus 로고
    • Vascular stiffness: Measurements, mechanisms and implications
    • 15320818
    • Wang Y-X, Fitch RM (2004) Vascular stiffness: measurements, mechanisms and implications. Curr Vasc Pharmacol 2:379-84
    • (2004) Curr Vasc Pharmacol , vol.2 , pp. 379-384
    • Wang, Y.-X.1    Fitch, R.M.2
  • 214
    • 84877946982 scopus 로고    scopus 로고
    • Defining single molecular forces required to activate integrin and notch signaling
    • 10.1126/science.1231041 3710701 23704575
    • Wang X, Ha T (2013) Defining single molecular forces required to activate integrin and notch signaling. Science 340:991-4. doi: 10.1126/science.1231041
    • (2013) Science , vol.340 , pp. 991-994
    • Wang, X.1    Ha, T.2
  • 215
    • 0027172919 scopus 로고
    • Mechanotransduction Across the Cell Surface and Through the Cytoskeleton
    • 7684161 80
    • Wang N, Butler JP, Ingber DE, Donald E (1993) Mechanotransduction Across the Cell Surface and Through the Cytoskeleton. Science 260:1124-1127, 80-
    • (1993) Science , vol.260 , pp. 1124-1127
    • Wang, N.1    Butler, J.P.2    Ingber, D.E.3    Donald, E.4
  • 217
    • 33644863157 scopus 로고    scopus 로고
    • Activation of Rac-1 and Cdc42 stabilizes the microvascular endothelial barrier
    • 10.1007/s00418-005-0080-2 16195887
    • Waschke J, Burger S, Curry F-RE, Drenckhahn D, Adamson RH (2006) Activation of Rac-1 and Cdc42 stabilizes the microvascular endothelial barrier. Histochem Cell Biol 125:397-406. doi: 10.1007/s00418-005-0080-2
    • (2006) Histochem Cell Biol , vol.125 , pp. 397-406
    • Waschke, J.1    Burger, S.2    Curry, F.-R.3    Drenckhahn, D.4    Adamson, R.H.5
  • 218
    • 79953136237 scopus 로고    scopus 로고
    • Integrins and cadherins join forces to form adhesive networks
    • 10.1242/jcs.064618 3115772 21444749
    • Weber GF, Bjerke MA, DeSimone DW (2011) Integrins and cadherins join forces to form adhesive networks. J Cell Sci 124:1183-93. doi: 10.1242/jcs.064618
    • (2011) J Cell Sci , vol.124 , pp. 1183-1193
    • Weber, G.F.1    Bjerke, M.A.2    Desimone, D.W.3
  • 219
    • 41949105625 scopus 로고    scopus 로고
    • Vascular permeability in cardiovascular disease and cancer
    • 10.1097/MOH.0b013e3282f97d86 18391792
    • Weis SM (2008) Vascular permeability in cardiovascular disease and cancer. Curr Opin Hematol 15:243-9. doi: 10.1097/MOH.0b013e3282f97d86
    • (2008) Curr Opin Hematol , vol.15 , pp. 243-249
    • Weis, S.M.1
  • 220
    • 25644449640 scopus 로고    scopus 로고
    • Pathophysiological consequences of VEGF-induced vascular permeability
    • 10.1038/nature03987 16177780
    • Weis SM, Cheresh DA (2005) Pathophysiological consequences of VEGF-induced vascular permeability. Nature 437:497-504. doi: 10.1038/nature03987
    • (2005) Nature , vol.437 , pp. 497-504
    • Weis, S.M.1    Cheresh, D.A.2
  • 221
    • 2342418629 scopus 로고    scopus 로고
    • Rho-family GTPases: It's not only Rac and Rho (and i like it)
    • 10.1242/jcs.01118 15020670
    • Wennerberg K, Der CJ (2004) Rho-family GTPases: it's not only Rac and Rho (and I like it). J Cell Sci 117:1301-12. doi: 10.1242/jcs.01118
    • (2004) J Cell Sci , vol.117 , pp. 1301-1312
    • Wennerberg, K.1    Der, C.J.2
  • 223
    • 15744364621 scopus 로고    scopus 로고
    • Rap1 GTPase inhibits leukocyte transmigration by promoting endothelial barrier function
    • 10.1074/jbc.M412595200 15661741
    • Wittchen ES, Worthylake RA, Kelly P, Casey PJ, Quilliam LA, Burridge K (2005) Rap1 GTPase inhibits leukocyte transmigration by promoting endothelial barrier function. J Biol Chem 280:11675-82. doi: 10.1074/jbc.M412595200
    • (2005) J Biol Chem , vol.280 , pp. 11675-11682
    • Wittchen, E.S.1    Worthylake, R.A.2    Kelly, P.3    Casey, P.J.4    Quilliam, L.A.5    Burridge, K.6
  • 224
    • 0042344706 scopus 로고    scopus 로고
    • Rho GTPases and the regulation of endothelial permeability
    • 12747959
    • Wójciak-Stothard B, Ridley AJ (2002) Rho GTPases and the regulation of endothelial permeability. Vascul Pharmacol 39:187-199
    • (2002) Vascul Pharmacol , vol.39 , pp. 187-199
    • Wójciak-Stothard, B.1    Ridley, A.J.2
  • 225
    • 0035040645 scopus 로고    scopus 로고
    • Rho and Rac but not Cdc42 regulate endothelial cell permeability
    • 11257000
    • Wójciak-Stothard B, Potempa S, Eichholtz T, Ridley AJ (2001) Rho and Rac but not Cdc42 regulate endothelial cell permeability. J Cell Sci 114:1343-55
    • (2001) J Cell Sci , vol.114 , pp. 1343-1355
    • Wójciak-Stothard, B.1    Potempa, S.2    Eichholtz, T.3    Ridley, A.J.4
  • 227
    • 0025186832 scopus 로고
    • Involvement of myosin light-chain kinase in endothelial cell retraction
    • 53190 2296576
    • Wysolmerski RB, Lagunoff D (1990) Involvement of myosin light-chain kinase in endothelial cell retraction. Proc Natl Acad Sci U S A 87:16-20
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 16-20
    • Wysolmerski, R.B.1    Lagunoff, D.2
  • 228
    • 79954420343 scopus 로고    scopus 로고
    • Role of p115RhoGEF in lipopolysaccharide-induced mouse brain microvascular endothelial barrier dysfunction
    • 10.1016/j.brainres.2011.02.059 21354111
    • Xiaolu D, Jing P, Fang H, Lifen Y, Liwen W, Ciliu Z, Fei Y (2011) Role of p115RhoGEF in lipopolysaccharide-induced mouse brain microvascular endothelial barrier dysfunction. Brain Res 1387:1-7. doi: 10.1016/j.brainres.2011.02.059
    • (2011) Brain Res , vol.1387 , pp. 1-7
    • Xiaolu, D.1    Jing, P.2    Fang, H.3    Lifen, Y.4    Liwen, W.5    Ciliu, Z.6    Fei, Y.7
  • 229
    • 79954554710 scopus 로고    scopus 로고
    • Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling
    • 10.1016/j.devcel.2011.02.010 3078994 21396893
    • Xu K, Sacharidou A, Fu S, Chong DC, Skaug B, Chen ZJ, Davis GE, Cleaver O (2011) Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling. Dev Cell 20:526-39. doi: 10.1016/j.devcel.2011.02.010
    • (2011) Dev Cell , vol.20 , pp. 526-539
    • Xu, K.1    Sacharidou, A.2    Fu, S.3    Chong, D.C.4    Skaug, B.5    Chen, Z.J.6    Davis, G.E.7    Cleaver, O.8
  • 230
    • 28344433073 scopus 로고    scopus 로고
    • Deconstructing the cadherin-catenin-actin complex
    • 10.1016/j.cell.2005.09.020 3368712 16325582
    • Yamada S, Pokutta S, Drees F, Weis WI, Nelson WJ (2005) Deconstructing the cadherin-catenin-actin complex. Cell 123:889-901. doi: 10.1016/j.cell.2005. 09.020
    • (2005) Cell , vol.123 , pp. 889-901
    • Yamada, S.1    Pokutta, S.2    Drees, F.3    Weis, W.I.4    Nelson, W.J.5
  • 232
    • 77951737987 scopus 로고    scopus 로고
    • The switchable integrin adhesome
    • 10.1242/jcs.066183 2858016 20410370
    • Zaidel-Bar R, Geiger B (2010) The switchable integrin adhesome. J Cell Sci 123:1385-8. doi: 10.1242/jcs.066183
    • (2010) J Cell Sci , vol.123 , pp. 1385-1388
    • Zaidel-Bar, R.1    Geiger, B.2
  • 233
    • 0034755942 scopus 로고    scopus 로고
    • Molecular complexity and dynamics of cell-matrix adhesions
    • 11707510
    • Zamir E, Geiger B (2001) Molecular complexity and dynamics of cell-matrix adhesions. J Cell Sci 114:3583-90
    • (2001) J Cell Sci , vol.114 , pp. 3583-3590
    • Zamir, E.1    Geiger, B.2
  • 234
    • 84880054103 scopus 로고    scopus 로고
    • Interaction of p190RhoGAP with C-terminal domain of p120- catenin modulates endothelial cytoskeleton and permeability
    • 10.1074/jbc.M112.432757 23653363
    • Zebda N, Tian Y, Tian X, Gawlak G, Higginbotham K, Reynolds AB, Birukova AA, Birukov KG (2013) Interaction of p190RhoGAP with C-terminal domain of p120- catenin modulates endothelial cytoskeleton and permeability. J Biol Chem 288:18290-9. doi: 10.1074/jbc.M112.432757
    • (2013) J Biol Chem , vol.288 , pp. 18290-18299
    • Zebda, N.1    Tian, Y.2    Tian, X.3    Gawlak, G.4    Higginbotham, K.5    Reynolds, A.B.6    Birukova, A.A.7    Birukov, K.G.8
  • 235
    • 0034002084 scopus 로고    scopus 로고
    • Endothelial cell retraction is induced by PAK2 monophosphorylation of myosin II
    • 10639334
    • Zeng Q, Lagunoff D, Masaracchia R, Goeckeler Z, Côté G, Wysolmerski R (2000) Endothelial cell retraction is induced by PAK2 monophosphorylation of myosin II. J Cell Sci 113(Pt 3):471-82
    • (2000) J Cell Sci , vol.113 , Issue.PART 3 , pp. 471-482
    • Zeng, Q.1    Lagunoff, D.2    Masaracchia, R.3    Goeckeler, Z.4    Côté, G.5    Wysolmerski, R.6
  • 236
    • 0035668525 scopus 로고    scopus 로고
    • Dbl family guanine nucleotide exchange factors
    • 11738596
    • Zheng Y (2001) Dbl family guanine nucleotide exchange factors. Trends Biochem Sci 26:724-732
    • (2001) Trends Biochem Sci , vol.26 , pp. 724-732
    • Zheng, Y.1
  • 237
    • 0030451173 scopus 로고    scopus 로고
    • The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor
    • 8969170
    • Zheng Y, Fischer DJ, Santos MF, Tigyi G, Pasteris NG, Gorski JL, Xu Y (1996) The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor. J Biol Chem 271:33169-72
    • (1996) J Biol Chem , vol.271 , pp. 33169-33172
    • Zheng, Y.1    Fischer, D.J.2    Santos, M.F.3    Tigyi, G.4    Pasteris, N.G.5    Gorski, J.L.6    Xu, Y.7
  • 238
    • 18244373458 scopus 로고    scopus 로고
    • Mechanisms, pathophysiology, and therapy of arterial stiffness
    • 10.1161/01.ATV.0000160548.78317.29 15731494
    • Zieman SJ, Melenovsky V, Kass DA (2005) Mechanisms, pathophysiology, and therapy of arterial stiffness. Arterioscler Thromb Vasc Biol 25:932-43. doi: 10.1161/01.ATV.0000160548.78317.29
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 932-943
    • Zieman, S.J.1    Melenovsky, V.2    Kass, D.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.