FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles

Journal of Biological Chemistry

Volumn 283, Issue 49, 2008, Pages 34002-34012

  Huber, Christoph ^a   Mårtensson, Annica ^a,b   Bokoch, Gary M ^a   Nemazee, David ^a   Gavin, Amanda L ^a,c  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Cebix Inc   (United States)

^c IMM 29 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; CHEMICAL ACTIVATION; DENDRIMERS; NUCLEIC ACIDS;

ACTIVE MEMBRANES; B CELL ANTIGEN RECEPTORS; B CELLS; B LYMPHOCYTES; BONE MARROWS; CYTOSKELETON; DENDRITIC CELLS; DEVELOPMENTAL STAGES; DO-MAINS; ENDOSOMES; EXCHANGE FACTORS; GENE FAMILIES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; IMMUNE SYSTEMS; IN CELLS; INTRACELLULAR LOCALIZATIONS; MEMBRANE RUFFLES; OVEREXPRESSION; PLECKSTRIN HOMOLOGY DOMAINS; VESICLE TRAFFICKING;

CELL MEMBRANES;

B LYMPHOCYTE ANTIGEN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PLECKSTRIN; PROTEIN CDC42; PROTEIN FGD2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CARBOXY TERMINAL SEQUENCE; CELL LINEAGE; CONTROLLED STUDY; CYTOSKELETON; DENDRITIC CELL; ENDOSOME; ENZYME ACTIVITY; FACIOGENITAL DYSPLASIA; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; BLOOD PROTEINS; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOSOMES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HELA CELLS; HUMANS; MACROPHAGES; MICE; PHOSPHOPROTEINS; SIGNAL TRANSDUCTION;

EID: 57749116036     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M803957200     Document Type: Article

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