Integrins in mechanotransduction

Current Opinion in Cell Biology

Volumn 25, Issue 5, 2013, Pages 613-618

  Ross, Tyler D ^a   Coon, Brian G ^a   Yun, Sanguk ^a   Baeyens, Nicolas ^a   Tanaka, Keiichiro ^a   Ouyang, Mingxing ^a   Schwartz, Martin A ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Cell Biology ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CD31 ANTIGEN; EPIDERMAL GROWTH FACTOR RECEPTOR 3; FILAMIN A; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; LIM PROTEIN; VANILLOID RECEPTOR 4; VASCULAR ENDOTHELIAL CADHERIN; VERY LATE ACTIVATION ANTIGEN 5; ZYXIN;

CELL ADHESION; CELL DIFFERENTIATION; CELL GROWTH; EXTRACELLULAR MATRIX; FLUORESCENCE RESONANCE ENERGY TRANSFER; MECHANOTRANSDUCTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; REVIEW; SHEAR STRESS; SIGNAL TRANSDUCTION;

ACTIN CYTOSKELETON; ANIMALS; CELL ADHESION; EXTRACELLULAR MATRIX; HUMANS; INTEGRINS; MECHANOTRANSDUCTION, CELLULAR;

EID: 84882859988     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2013.05.006     Document Type: Review

References (52)

1. Lucitti J.L., Jones E.A.V., Huang C., et al. Vascular remodeling of the mouse yolk sac requires hemodynamic force. Development 2007, 134:3317-3326.
2. Yashiro K., Shiratori H., Hamada H. Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch. Nature 2007, 450:285-288.
3. Planas-Paz L., Strilić B., Goedecke A., et al. Mechanoinduction of lymph vessel expansion. EMBO J 2012, 31:788-804.
4. Sabine A., Agalarov Y., Maby-El Hajjami H., et al. Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation. Dev Cell 2012, 22:430-445.
5. Feaver R.E., Gelfand B.D., Wang C., et al. Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation. Circ Res 2010, 106:1703-1711.
6. Orr A.W., Hastings N.E., Blackman B.R., Wamhoff B.R. Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis. J Vasc Res 2010, 47:168-180.
7. Jaalouk D.E., Lammerding J. Mechanotransduction gone awry. Nat Rev Mol Cell Biol 2009, 10:63-73.
8. Rangaswami H., Schwappacher R., Marathe N., et al. Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts. Sci Signal 2010, 3:ra91.
9. Tschumperlin D.J., Boudreault F., Liu F. Recent advances and new opportunities in lung mechanobiology. J Biomech 2010, 43:99-107.
10. DuFort C.C., Paszek M.J., Weaver V.M. Balancing forces: architectural control of mechanotransduction. Nat Rev Mol Cell Biol 2011, 12:308-319.
11. Liu F., Mih J.D., Shea B.S., et al. Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression. J Cell Biol 2010, 190:693-706.
12. Kothapalli D., Liu S.-L., Bae Y.H., et al. Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening. Cell Rep 2012, 2:1259-1271.
13. Wang J.H.-C., Thampatty B.P. An introductory review of cell mechanobiology. Biomech Model Mechanobiol 2006, 5:1-16.
14. Hoffman B.D., Grashoff C., Schwartz M.A. Dynamic molecular processes mediate cellular mechanotransduction. Nature 2011, 475:316-323.
15. Butcher D.T., Alliston T., Weaver V.M. A tense situation: forcing tumour progression. Nat Rev Cancer 2009, 9:108-122.
16. Engler A.J., Sen S., Sweeney H.L., Discher D.E. Matrix elasticity directs stem cell lineage specification. Cell 2006, 126:677-689.
17. Geiger B., Spatz J.P., Bershadsky A.D. Environmental sensing through focal adhesions. Nat Rev Mol Cell Biol 2009, 10:21-33.
18. Burridge K., Wittchen E.S. The tension mounts: stress fibers as force-generating mechanotransducers. J Cell Biol 2013, 200:9-19.
19. Chen W., Lou J., Evans E.A., Zhu C. Observing force-regulated conformational changes and ligand dissociation from a single integrin on cells. J Cell Biol 2012, 199:497-512.
20. Kong F., Li Z., Parks W.M., et al. Cyclic mechanical reinforcement of integrin-ligand interactions. Mol Cell 2013, 49:1060-1068.
21. del Rio A., Perez-Jimenez R., Liu R., et al. Stretching single talin rod molecules activates vinculin binding. Science 2009, 323:638-641.
22. Margadant F., Chew L.L., Hu X., et al. Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin. PLoS Biol 2011, 9:e1001223.
23. Grashoff C., Hoffman B.D., Brenner M.D., et al. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature 2010, 466:263-266.
24. Katsumi A., Naoe T., Matsushita T., et al. Integrin activation and matrix binding mediate cellular responses to mechanical stretch. J Biol Chem 2005, 280:16546-16549.
25. Thodeti C.K., Matthews B., Ravi A., et al. TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. Circ Res 2009, 104:1123-1130.
26. Ehrlicher A.J., Nakamura F., Hartwig J.H., et al. Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A. Nature 2011, 478:260-263.
27. Rognoni L., Stigler J., Pelz B., et al. Dynamic force sensing of filamin revealed in single-molecule experiments. Proc Natl Acad Sci U S A 2012, 109:19679-19684.
28. Shifrin Y., Arora P.D., Ohta Y., et al. The role of FilGAP-filamin A interactions in mechanoprotection. Mol Biol Cell 2009, 20:1269-1279.
29. Katsumi A., Milanini J., Kiosses W.B., et al. Effects of cell tension on the small GTPase Rac. J Cell Biol 2002, 158:153-164.
30. Guilluy C., Swaminathan V., Garcia-Mata R., et al. The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins. Nat Cell Biol 2011, 13:722-727.
31. Hoffman L.M., Jensen C.C., Chaturvedi A., et al. Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators. Mol Biol Cell 2012, 23:1846-1859.
32. Chapin L.M., Blankman E., Smith M.A., et al. Lateral communication between stress fiber sarcomeres facilitates a local remodeling response. Biophys J 2012, 103:2082-2092.
33. Anwar M.A., Shalhoub J., Lim C.S., et al. The effect of pressure-induced mechanical stretch on vascular wall differential gene expression. J Vasc Res 2012, 49:463-478.
34. Nemir S., West J.L. Synthetic materials in the study of cell response to substrate rigidity. Ann Biomed Eng 2010, 38:2-20.
35. Moore S.W., Roca-Cusachs P., Sheetz M.P. Stretchy proteins on stretchy substrates: the important elements of integrin-mediated rigidity sensing. Dev Cell 2010, 19:194-206.
36. Chan C.E., Odde D.J. Traction dynamics of filopodia on compliant substrates. Science 2008, 322:1687-1691.
37. Giannone G., Dubin-Thaler B.J., Döbereiner H.-G., et al. Periodic lamellipodial contractions correlate with rearward actin waves. Cell 2004, 116:431-443.
38. Plotnikov S.V., Pasapera A.M., Sabass B., Waterman C.M. Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration. Cell 2012, 151:1513-1527.
39. Prager-Khoutorsky M., Lichtenstein A., Krishnan R., et al. Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing. Nat Cell Biol 2011, 13:1457-1465.
40. Dupont S., Morsut L., Aragona M., et al. Role of YAP/TAZ in mechanotransduction. Nature 2011, 474:179-183.
41. Wada K.-I., Itoga K., Okano T., et al. Hippo pathway regulation by cell morphology and stress fibers. Development 2011, 138:3907-3914.
42. Katsumi A., Orr A.W., Tzima E., Schwartz M.A. Integrins in mechanotransduction. J Biol Chem 2004, 279:12001-12004.
43. Coste B., Mathur J., Schmidt M., et al. Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels. Science 2010, 330:55-60.
44. McHugh B.J., Buttery R., Lad Y., et al. Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum. J Cell Sci 2010, 123:51-61.
45. 2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site. J Biol Chem 2003, 278:26541-26549.
46. Batra N., Burra S., Siller-Jackson A.J., et al. Mechanical stress-activated integrin alpha5beta1 induces opening of connexin 43 hemichannels. Proc Natl Acad Sci U S A 2012, 109:3359-3364.
47. Tarsa P.B., Brau R.R., Barch M., et al. Detecting force-induced molecular transitions with fluorescence resonant energy transfer. Angew Chem Int Ed Engl 2007, 46:1999-2001.
48. Meng F., Sachs F. Visualizing dynamic cytoplasmic forces with a compliance-matched FRET sensor. J Cell Sci 2011, 124:261-269.
49. Meng F., Suchyna T.M., Sachs F. A fluorescence energy transfer-based mechanical stress sensor for specific proteins in situ. FEBS J 2008, 275:3072-3087.
50. Borghi N., Sorokina M., Shcherbakova O.G., et al. E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch. Proc Natl Acad Sci U S A 2012, 109:12568-12573.
51. Conway D.E., Breckenridge M.T., Hinde E., et al. Fluid shear stress on endothelial cells modulates mechanical tension across VE-Cadherin and PECAM-1. Curr Biol 2013.
52. Gardel M.L., Schneider I.C., Aratyn-Schaus Y., Waterman C.M. Mechanical integration of actin and adhesion dynamics in cell migration. Annu Rev Cell Dev Biol 2010, 26:315-333.