Transient and prolonged increase in endothelial permeability induced by histamine and thrombin: Role of protein kinases, calcium, and RhoA

Circulation Research

Volumn 83, Issue 11, 1998, Pages 1115-1123

  Van Nieuw Amerongen, Geerten P ^a   Draijer, Richard ^a   Vermeer, Mario A ^a   Van Hinsbergh, Victor W M ^a,b,c  

^a LEIDEN UNIVERSITY   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c TNO   (Netherlands)

Author keywords

Human endothelial cell; Protein kinase C; Protein tyrosine kinase; RhoA

Indexed keywords

CALCIUM; CALMODULIN; COMPLEMENT COMPONENT C3; DAIDZEIN; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GENISTEIN; HERBIMYCIN A; HISTAMINE; MYOSIN LIGHT CHAIN; PROTEIN KINASE; PROTEIN TYROSINE KINASE INHIBITOR; RHO FACTOR; SODIUM 22; THROMBIN;

ARTICLE; CHELATION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; ENZYME ANALYSIS; HISTAMINE RELEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; MEMBRANE PERMEABILITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

EID: 0032583083     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.res.83.11.1115     Document Type: Article

References (41)

1. Baluk P, Hirata A, Thurston G, Fujiwara T, Neal CR, Michel CC, McDonald DM. Endothelial gaps: time course of formation and closure in inflamed venules of rats. Am J Physiol. 1997;272:L155-L170.
2. Buckley IK, Ryan GB. Increased vascular permeability: the effect of histamine and serotonin on rat mesenteric blood vessels in vivo. Am J Pathol. 1969;55:329-347.
3. Schnittler HJ, Wilke A, Gress T, Suttorp N, Drenckhahn D. Role of actin and myosin in the control of paracellular permeability in pig, rat and human vascular endothelium. J Physiol. 1990;431:379-401.
4. Van Hinsbergh VWM. Endothelial permeability for macromolecules: mechanistic aspects of pathophysiological modulation. Arterioscler Thromb Vasc Biol. 1997;17:1018-1023.
5. Lum H, Malik AB. Regulation of vascular endothelial barrier function. Am J Physiol. 1994;267:L223-L241.
6. Curry FE. Modulation of venular microvessel permeability by calcium influx into endothelial cells. FASEB J. 1992;6:2456-2466.
7. Granger DN, Korthuis RJ. Physiologic mechanisms of postischemic tissue injury. Ann Rev Physiol. 1995;57:311-332.
8. Cuenoud HF, Joris I, Langer RS, Majno G. Focal arteriolar insudation: a response of arterioles to chronic nonspecific irritation. Am J Pathol. 1987;127:592-604.
9. Joris I, Cuenoud HF, Doern GV, Underwood JM, Majno G. Capillary leakage in inflammation: a study by vascular labeling. Am J Pathol. 1990;137:1353-1363.
10. Dejana E. Endothelial adherens junctions: implications in the control of vascular permeability and angiogenesis. J Clin Invest. 1996;98: 1949-1953.
11. Roberts WG, Palade GE. Increased microvascular permeability and en-dothelial fenestration induced by vascular endothelial growth factor. J Cell Sci. 1995;108:2369-2379.
12. Neal CR, Michel CC. Transcellular gaps in microvascular walls of frog and rat when permeability is increased by perfusion with the ionophore A23187. J Physiol. 1995;488:427-437.
13. Esser S, Wolburg K, Wolburg H, Breier G, Kurzchalia T, Risau W. Vascular endothelial growth factor induces endothelial fenestrations in vitro. J Cell Biol. 1998;140:947-959.
14. Garcia JG, Pavalko FM, Patterson CE. Vascular endothelial cell activation and permeability responses to thrombin. Blood Coagul Fibrinolysis. 1995;6:609-626.
15. Morgan MJ, Fenton JW II, Malik AB. Alpha-thrombin-induced pulmonary vasoconstriction. J Appl Physiol. 1987;63:1993-2000.
16. Moy AB, Van Engelenhoven J, Bodmer J, Kamath J, Keese C, Giaever I, Shasby S, Shasby DM. Histamine and thrombin modulate endothelial focal adhesion through centripetal and centrifugal forces. J Clin Invest. 1996;97:1020-1027.
17. Buchan KW, Martin W. Modulation of barrier function of bovine aortic and pulmonary artery endothelial cells: dissociation from cytosolic calcium content. Br J Pharmacol. 1992;107:932-938.
18. Lynch JJ, Ferro TJ, Blumenstock FA, Brockenauer AM, Malik AB. Increased endothelial albumin permeability mediated by protein kinase C activation. J Clin Invest. 1990;85:1991-1998.
19. Diwan AH, Honkanen RE, Schaeffer RC, Strada SJ, Thompson WJ. Inhibition of serine-threonine protein phosphatases decreases barrier function of rat pulmonary microvascular endothelial cells. J Cell Physiol. 1997; 171:259-270.
20. Verin AD, Patterson CE, Day MA, Garcia JG. Regulation of endothelial cell gap formation and barrier function by myosin-associated phosphatase activities. Am J Physiol. 1995;269:L99-L108.
21. Draijer R, Atsma DE, van der Laarse A, van Hinsbergh VW. cGMP and nitric oxide modulate thrombin-induced endothelial permeability: regulation via different pathways in human aortic and umbilical vein endothelial cells. Circ Res. 1995;76:199-208.
22. Langeler EG, van Hinsbergh VW. Characterization of an in vitro model to study the permeability of human arterial endothelial cell monolayers. Thromb Haemost. 1988;60:240-246.
23. Goeckeler ZM, Wysolmerski RB. Myosin light chain kinase-regulated endothelial cell contraction: the relationship between isometric tension, actin polymerization, and myosin phosphorylation. J Cell Biol. 1995;130:613-627.
24. Chrzanowska-Wodnicka M, Burridge K. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J Cell Biol. 1996;133:1403-1415.
25. Garcia JGN, Davis HW, Patterson CE. Regulation of endothelial gap formation and barrier dysfunction: role of myosin light chain phosphorylation. J Cell Phys. 1998;163:510-522.
26. Ridley AJ, Hall A. The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell. 1992;70:389-399.
27. Jalink K, van Corven EJ, Hengeveld T, Morii N, Narumiya S, Moolenaar WH. Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J Cell Biol. 1994;126:801-810.
28. Fujihara H, Walker LA, Gong MC, Lemichez E, Boquet P, Somlyo AV, Somlyo AP. Inhibition of RhoA translocation and calcium sensitization by in vivo ADP-ribosylation with the chimeric toxin DC3B. Mol Biol Cell. 1997;8:2437-2447.
29. Bloemers SM, Verheule S, Peppelenbosch MP, Smit MJ, Tertoolen LGJ, de Laat S. Sensitization of the histamine H, receptor by increased ligand affinity. J Biol Chem. 1998;273:2249-2255.
30. 2+ influx and protein tyrosine phosphorylation in endothelial cells is inhibited by herbimycin A. Biochem Biophys Res Commun. 1994;202: 1651-1656.
31. Fleming I, Fisslthaler B, Busse R. Calcium signaling in endothelial cells involves activation of tyrosine kinases and leads to activation of MAP kinase. Circ Res. 1995;76:522-529.
32. Rabiet MJ, Plantier JL, Rival Y, Genoux Y, Lampugnani MG, Dejana E. Thrombin-induced increase in endothelial permeability is associated with changes in cell-to-cell junction organization. Arterioscler Thromb Vasc Biol. 1996;16:488-496.
33. Schaphorst KL, Pavalko FM, Patterson CE, Garcia JG. Thrombin-mediated focal adhesion plaque reorganization in endothelium: role of protein phosphorylation. Am J Respir Cell Mol Biol. 1997;17:443-455.
34. Hippenstiel S, Tannert Otto S, Vollrath N, Krull M, Just I, Aktories K, von Eichel Streiber C, Suttorp N. Glucosylation of small GTP-binding Rho proteins disrupts endothelial barrier function. Am J Physiol. 1997; 272:L38-L43.
35. Cross MJ, Roberts S, Ridley AJ, Hodgkin MN, Stewart A, Claesson Welsh L, Wakelam MJO. Stimulation of actin stress fibre formation mediated by activation of phospholipase D. Curr Biol. 1996;6: 588-597.
36. Amano M, Ito M, Kimura K, Fukata Y, Chihara K, Nakano T, Matsuura Y, Kaibuchi K. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J Biol Chem. 1996;271:20246-20249.
37. Drenckhahn D, Wagner J. Stress fibers in the splenic sinus endothelium in situ: molecular structure, relationship to the extracellular matrix, and contractility. J Cell Biol. 1986;102:1738-1747.
38. Shasby DM, Stevens T, Ries D, Moy AB, Kamath JM, Kamath AM, Shasby SS. Thrombin inhibits myosin light chain dephosphorylation in endothelial cells. Am J Physiol. 1997;272:L311-L319.
39. Wheeler-Jones CPD, May MJ, Morgan AJ, Pearson JD. Protein tyrosine kinases regulate agonist-stimulated prostacyclin release but not von Willebrand factor secretion from human umbilical vein endothelial cells. Biochem J. 1996;315:407-416.
40. Yamada Y, Furumichi T, Furui H, Yokoi T, Ito T, Yamauchi K, Yokota M, Hayashi H, Saito H. Roles of calcium, cyclic nucleotides, and protein kinase C in regulation of endothelial permeability. Arteriosclerosis. 1990; 10:410-420.
41. Bussolino F, Silvagno F, Garbarino G, Costamagna C, Sanavio F, Arese M, Soldi R, Aglietta M, Pescarmona G, Camussi G, Bosia A. Human endothelial cells are targets for platelet-activating factor (PAF). J Biol Chem. 1994;269:2877-2886.