메뉴 건너뛰기




Volumn 6, Issue 11, 2005, Pages 957-966

RhoGDIs revisited: Novel roles in Rho regulation

Author keywords

Cancer; Cdc42; Displacement factor; Guanine nucleotide dissociation inhibitor; Infection; Phosphorylation; Rac; Rho; rhoGDI; Structure

Indexed keywords

BINDING PROTEIN; GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; GUANOSINE TRIPHOSPHATE; PROTEIN CDC42; RAC PROTEIN; REGULATOR PROTEIN; RHO FACTOR;

EID: 26944440432     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2005.00335.x     Document Type: Review
Times cited : (111)

References (69)
  • 1
    • 0033058184 scopus 로고    scopus 로고
    • Rho guanine dissociation inhibitors: Pivotal molecules in cellular signalling
    • Olofsson B. Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling. Cell Signal 1999;11:545-554.
    • (1999) Cell Signal , vol.11 , pp. 545-554
    • Olofsson, B.1
  • 2
    • 0025073547 scopus 로고
    • Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the Rho proteins, ras p21-like small GTP-binding proteins
    • Fukumoto Y, Kaibuchi K, Hori Y, Fujioka H, Araki S, Ueda T, Kikuchi A, Takai Y. Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the Rho proteins, ras p21-like small GTP-binding proteins. Oncogene 1990;5:1321-1328.
    • (1990) Oncogene , vol.5 , pp. 1321-1328
    • Fukumoto, Y.1    Kaibuchi, K.2    Hori, Y.3    Fujioka, H.4    Araki, S.5    Ueda, T.6    Kikuchi, A.7    Takai, Y.8
  • 3
    • 0026475383 scopus 로고
    • The identification and characterization of a GDP-dissociation inhibitor (GDI) for the Cdc42Hs protein
    • Leonard D, Hart M, Platko J, Eva A, Henzel W, Evans T, Cerione RA. The identification and characterization of a GDP-dissociation inhibitor (GDI) for the Cdc42Hs protein. J Biol Chem 1992;267:22860-22868.
    • (1992) J. Biol. Chem. , vol.267 , pp. 22860-22868
    • Leonard, D.1    Hart, M.2    Platko, J.3    Eva, A.4    Henzel, W.5    Evans, T.6    Cerione, R.A.7
  • 4
    • 0027526303 scopus 로고
    • cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins
    • Lelias JM, Adra CN, Wulf GM, Guillemot JC, Khagad M, Caput D, Lim B. cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins. Proc Natl Acad Sci USA 1993;90:1479-1483.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1479-1483
    • Lelias, J.M.1    Adra, C.N.2    Wulf, G.M.3    Guillemot, J.C.4    Khagad, M.5    Caput, D.6    Lim, B.7
  • 5
    • 0032579315 scopus 로고    scopus 로고
    • Differential properties of D4/LyGDI versus RhoGDI: Phosphorylation and rho GTPase selectivity
    • Gorvel JP, Chang TC, Boretto J, Azuma T, Chavrier P. Differential properties of D4/LyGDI versus RhoGDI: phosphorylation and rho GTPase selectivity. FEBS Lett 1998;422:269-273.
    • (1998) FEBS Lett. , vol.422 , pp. 269-273
    • Gorvel, J.P.1    Chang, T.C.2    Boretto, J.3    Azuma, T.4    Chavrier, P.5
  • 6
    • 0029828539 scopus 로고    scopus 로고
    • RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG
    • Zalcman G, Closson V, Camonis J, Honore N, Rousseau-Merck MF, Tavitian A, Olofsson B. RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG. J Biol Chem 1996;271:30366-30374.
    • (1996) J. Biol. Chem. , vol.271 , pp. 30366-30374
    • Zalcman, G.1    Closson, V.2    Camonis, J.3    Honore, N.4    Rousseau-Merck, M.F.5    Tavitian, A.6    Olofsson, B.7
  • 8
    • 0036240521 scopus 로고    scopus 로고
    • RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain
    • Brunet N, Morin A, Olofsson B. RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain. Traffic 2002;3:342-357.
    • (2002) Traffic , vol.3 , pp. 342-357
    • Brunet, N.1    Morin, A.2    Olofsson, B.3
  • 9
    • 0031570337 scopus 로고    scopus 로고
    • A modulator of rho family G proteins, rhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm
    • Keep NH, Barnes M, Barsukov I, Badii R, Lian LY, Segal AW, Moody PC, Roberts GC. A modulator of rho family G proteins, rhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm. Structure 1997;5:623-633.
    • (1997) Structure , vol.5 , pp. 623-633
    • Keep, N.H.1    Barnes, M.2    Barsukov, I.3    Badii, R.4    Lian, L.Y.5    Segal, A.W.6    Moody, P.C.7    Roberts, G.C.8
  • 13
    • 0034603198 scopus 로고    scopus 로고
    • Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI
    • Hoffman GR, Nassar N, Cerione RA. Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI. Cell 2000;100:345-356.
    • (2000) Cell , vol.100 , pp. 345-356
    • Hoffman, G.R.1    Nassar, N.2    Cerione, R.A.3
  • 15
    • 14644435825 scopus 로고    scopus 로고
    • Intrinsically unstructured proteins and their functions
    • Dyson HJ, Wright PE. Intrinsically unstructured proteins and their functions. Nat Rev Mol Cell Biol 2005;6:197-208.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 197-208
    • Dyson, H.J.1    Wright, P.E.2
  • 16
    • 0033049740 scopus 로고    scopus 로고
    • Kinetics of Cdc42 membrane extraction by Rho-GDI monitored by real-time fluorescence resonance energy transfer
    • Nomanbhoy TK, Erickson JW, Cerione RA. Kinetics of Cdc42 membrane extraction by Rho-GDI monitored by real-time fluorescence resonance energy transfer. Biochemistry 1999;38:1744-1750.
    • (1999) Biochemistry , vol.38 , pp. 1744-1750
    • Nomanbhoy, T.K.1    Erickson, J.W.2    Cerione, R.A.3
  • 18
    • 14244255010 scopus 로고    scopus 로고
    • Uncoupling of inhibitory and shuttling functions of rho GDP dissociation inhibitors
    • Dransart E, Morin A, Cherfils J, Olofsson B. Uncoupling of inhibitory and shuttling functions of rho GDP dissociation inhibitors. J Biol Chem 2005;280:4674-4683.
    • (2005) J. Biol. Chem. , vol.280 , pp. 4674-4683
    • Dransart, E.1    Morin, A.2    Cherfils, J.3    Olofsson, B.4
  • 19
  • 20
    • 0028145722 scopus 로고
    • Participation of the small molecular weight GTP-binding protein Rac1 in cell-free activation and assembly of the respiratory burst oxidase. Inhibition by a carboxyl-terminal Rac peptice
    • Kreck ML, Uhlinger DJ, Tyagi SR, Inge KL, Lambeth JD. Participation of the small molecular weight GTP-binding protein Rac1 in cell-free activation and assembly of the respiratory burst oxidase. Inhibition by a carboxyl-terminal Rac peptice. J Biol Chem 1994;269:4161-4168.
    • (1994) J. Biol. Chem. , vol.269 , pp. 4161-4168
    • Kreck, M.L.1    Uhlinger, D.J.2    Tyagi, S.R.3    Inge, K.L.4    Lambeth, J.D.5
  • 21
    • 2642563696 scopus 로고    scopus 로고
    • Structural principles for the multispecificity of small GTP-binding proteins
    • Biou V, Cherfils J. Structural principles for the multispecificity of small GTP-binding proteins. Biochemistry 2004;43:6833-6840.
    • (2004) Biochemistry , vol.43 , pp. 6833-6840
    • Biou, V.1    Cherfils, J.2
  • 22
    • 0038363325 scopus 로고    scopus 로고
    • Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam
    • Robbe K, Otto-Bruc A, Chardin P, Antonny B, Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam. J Biol Chem 2003;278:4756-4762.
    • (2003) J. Biol. Chem. , vol.278 , pp. 4756-4762
    • Robbe, K.1    Otto-Bruc, A.2    Chardin, P.3    Antonny, B.4
  • 23
    • 13444252631 scopus 로고    scopus 로고
    • GEF means go: Turning on RHO GTPases with guanine nucleotice-exchange factors
    • Rossman KLCJ, Sondek J. GEF means go: turning on RHO GTPases with guanine nucleotice-exchange factors. Nat Rev Mol Cell Biol 2005;6:167-180.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 167-180
    • Rossman, K.L.C.J.1    Sondek, J.2
  • 24
    • 2542588542 scopus 로고    scopus 로고
    • Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes
    • Ivetic A, Ridley AJ. Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes. Immunology 2004;112:165-176.
    • (2004) Immunology , vol.112 , pp. 165-176
    • Ivetic, A.1    Ridley, A.J.2
  • 26
    • 0033606997 scopus 로고    scopus 로고
    • Expression level, subcellular distribution and rho-GDI binding affinity of merlin in comparison with Ezrin/Radixin/Moesin proteins
    • Maeda M, Matsui T, Imamura M, Tsukita S, Tsukita S. Expression level, subcellular distribution and rho-GDI binding affinity of merlin in comparison with Ezrin/Radixin/Moesin proteins. Oncogene 1999;18:4788-4797.
    • (1999) Oncogene , vol.18 , pp. 4788-4797
    • Maeda, M.1    Matsui, T.2    Imamura, M.3    Tsukita, S.4    Tsukita, S.5
  • 27
    • 0037408391 scopus 로고    scopus 로고
    • The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI
    • Yamashita T, Tohyama M. The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI. Nat Neurosci 2003;6:461-467.
    • (2003) Nat. Neurosci. , vol.6 , pp. 461-467
    • Yamashita, T.1    Tohyama, M.2
  • 28
    • 13844297410 scopus 로고    scopus 로고
    • A truncated tropo-myosine-related kinase B receptor, T1, regulates glial cell morphology via Rho GDP dissociation inhibitor 1
    • Ohira K, Kumanogoh H, Sahara Y, Homma KJ, Hirai H, Nakamura S, Hayashi M. A truncated tropo-myosine-related kinase B receptor, T1, regulates glial cell morphology via Rho GDP dissociation inhibitor 1. J Neurosci 2005;25:1343-1353.
    • (2005) J. Neurosci. , vol.25 , pp. 1343-1353
    • Ohira, K.1    Kumanogoh, H.2    Sahara, Y.3    Homma, K.J.4    Hirai, H.5    Nakamura, S.6    Hayashi, M.7
  • 31
    • 0033956628 scopus 로고    scopus 로고
    • Vav, a GDP/GTP nucleotide exchange factor, interacts with GDIs, proteins that inhibit GDP/GTP dissociation
    • Groysman M, Russek CS, Katzav S. Vav, a GDP/GTP nucleotide exchange factor, interacts with GDIs, proteins that inhibit GDP/GTP dissociation. FEBS Lett 2000;467:75-80.
    • (2000) FEBS Lett. , vol.467 , pp. 75-80
    • Groysman, M.1    Russek, C.S.2    Katzav, S.3
  • 32
    • 0037147241 scopus 로고    scopus 로고
    • Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways
    • Groysman M, Hornstein I, Alcover A, Katzav S. Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways. J Biol Chem 2002;277:50121-50130.
    • (2002) J. Biol. Chem. , vol.277 , pp. 50121-50130
    • Groysman, M.1    Hornstein, I.2    Alcover, A.3    Katzav, S.4
  • 33
    • 3042812985 scopus 로고    scopus 로고
    • Analysis of cell-cycle specific localization of the Rdi1p RhoGDI and the structural determinants required for Cdc42p membrane localization and clustering at sites of polarized growth
    • Richman TJ, Toenjes KA, Morales SE, Cole KC, Wasserman BT, Taylor CM, Koster JA, Whelihan MF, Johnson DI. Analysis of cell-cycle specific localization of the Rdi1p RhoGDI and the structural determinants required for Cdc42p membrane localization and clustering at sites of polarized growth. Curr Genet 2004;45:339-349.
    • (2004) Curr. Genet. , vol.45 , pp. 339-349
    • Richman, T.J.1    Toenjes, K.A.2    Morales, S.E.3    Cole, K.C.4    Wasserman, B.T.5    Taylor, C.M.6    Koster, J.A.7    Whelihan, M.F.8    Johnson, D.I.9
  • 34
    • 0037081858 scopus 로고    scopus 로고
    • Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes
    • Forget MA, Desrosiers RR, Gingras D, Beliveau R. Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes. Biochem J 2002;361:243-254.
    • (2002) Biochem. J. , vol.361 , pp. 243-254
    • Forget, M.A.1    Desrosiers, R.R.2    Gingras, D.3    Beliveau, R.4
  • 35
    • 0037730396 scopus 로고    scopus 로고
    • cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI
    • Tamma G, Klussmann E, Procino G, Svelto M, Rosenthal W, Valenti G. cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI. J Cell Sci 2003;116:1519-1525.
    • (2003) J. Cell Sci. , vol.116 , pp. 1519-1525
    • Tamma, G.1    Klussmann, E.2    Procino, G.3    Svelto, M.4    Rosenthal, W.5    Valenti, G.6
  • 36
    • 0037805583 scopus 로고    scopus 로고
    • Serine phosphorylation negatively regulates RhoA in vivo
    • Ellerbroek SM, Wennerberg K, Burridge K. Serine phosphorylation negatively regulates RhoA in vivo. J Biol Chem 2003;278:19023-19031.
    • (2003) J. Biol. Chem. , vol.278 , pp. 19023-19031
    • Ellerbroek, S.M.1    Wennerberg, K.2    Burridge, K.3
  • 37
    • 0035933870 scopus 로고    scopus 로고
    • Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier function
    • Mehta D, Rahman A, Malik AB. Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier function. J Biol Chem 2001;276:22614-22620.
    • (2001) J. Biol. Chem. , vol.276 , pp. 22614-22620
    • Mehta, D.1    Rahman, A.2    Malik, A.B.3
  • 38
    • 3042839349 scopus 로고    scopus 로고
    • Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase
    • DerMardirossian C, Schnelzer A, Bokoch GM. Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase. Mol Cell 2004;15:117-127.
    • (2004) Mol. Cell , vol.15 , pp. 117-127
    • DerMardirossian, C.1    Schnelzer, A.2    Bokoch, G.M.3
  • 41
    • 0035887166 scopus 로고    scopus 로고
    • RhoGDI-binding-defective mutant of Cdc42Hs targets to membranes and activates filopodia formation but does not cycle with the cytosol of mammalian cells
    • Gibson RM, Wilson-Delfosse AL. RhoGDI-binding-defective mutant of Cdc42Hs targets to membranes and activates filopodia formation but does not cycle with the cytosol of mammalian cells. Biochem J 2001;359:285-294.
    • (2001) Biochem. J. , vol.359 , pp. 285-294
    • Gibson, R.M.1    Wilson-Delfosse, A.L.2
  • 42
    • 1642307142 scopus 로고    scopus 로고
    • An activating mutant of Rac1 that fails to interact with Rho GDP-dissociation inhibitor stimulates membrane ruffling in mammalian cells
    • Gandhi PN, Gibson RM, Tong X, Miyoshi J, Takai Y, Konieczkowski M, Secor JR, Wilson-Delfosse AL. An activating mutant of Rac1 that fails to interact with Rho GDP-dissociation inhibitor stimulates membrane ruffling in mammalian cells. Biochem J 2004;378:409-419.
    • (2004) Biochem. J. , vol.378 , pp. 409-419
    • Gandhi, P.N.1    Gibson, R.M.2    Tong, X.3    Miyoshi, J.4    Takai, Y.5    Konieczkowski, M.6    Secor, J.R.7    Wilson-Delfosse, A.L.8
  • 43
    • 0042761752 scopus 로고    scopus 로고
    • RhoGDI is required for Cdc42-mediated cellular transformation
    • Lin Q, Fuji RN, Yang W, Cerione RA. RhoGDI is required for Cdc42-mediated cellular transformation. Curr Biol 2003;13:1469-1479.
    • (2003) Curr. Biol. , vol.13 , pp. 1469-1479
    • Lin, Q.1    Fuji, R.N.2    Yang, W.3    Cerione, R.A.4
  • 45
    • 0027232261 scopus 로고
    • A novel role for RhoGDI as an inhibitor of GAP proteins
    • Hancock JF, Hall A. A novel role for RhoGDI as an inhibitor of GAP proteins. Embo J 1993;12:1915-1921.
    • (1993) Embo. J. , vol.12 , pp. 1915-1921
    • Hancock, J.F.1    Hall, A.2
  • 46
    • 0030040750 scopus 로고    scopus 로고
    • Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
    • Lang P, Gesbert F, Delespine-Carmagnat M, Stancou R, Pouchelet M, Bertoglio J. Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. Embo J 1996;15:510-519.
    • (1996) Embo. J. , vol.15 , pp. 510-519
    • Lang, P.1    Gesbert, F.2    Delespine-Carmagnat, M.3    Stancou, R.4    Pouchelet, M.5    Bertoglio, J.6
  • 50
    • 20444480169 scopus 로고    scopus 로고
    • Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome-mediated degradation in vascular smooth muscle cells
    • Rolli-Derkinderen M, Sauzeau V, Boyer L, Lemichez E, Baron C, Henrion D, Loirand G, Pacaud P. Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome-mediated degradation in vascular smooth muscle cells. Circ Res 2005;96:1152-1160.
    • (2005) Circ. Res. , vol.96 , pp. 1152-1160
    • Rolli-Derkinderen, M.1    Sauzeau, V.2    Boyer, L.3    Lemichez, E.4    Baron, C.5    Henrion, D.6    Loirand, G.7    Pacaud, P.8
  • 52
    • 0034706389 scopus 로고    scopus 로고
    • Rho proteins and the cellular mechanisms of mental retardation
    • Ramakers GJ. Rho proteins and the cellular mechanisms of mental retardation. Am J Med Genet 2000;94:367-371.
    • (2000) Am. J. Med. Genet. , vol.94 , pp. 367-371
    • Ramakers, G.J.1
  • 55
    • 17844406602 scopus 로고    scopus 로고
    • Bacterial cytotoxins: Targeting eukaryotic switches
    • Aktories K, Barbieri JT. Bacterial cytotoxins: targeting eukaryotic switches. Nat Rev Microbiol 2005;3:397-410.
    • (2005) Nat. Rev. Microbiol. , vol.3 , pp. 397-410
    • Aktories, K.1    Barbieri, J.T.2
  • 57
    • 0041707712 scopus 로고    scopus 로고
    • Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 complex
    • Genth H, Gerhard R, Maeda A, Amano M, Kaibuchi K, Aktories K, Just I. Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 complex. J Biol Chem 2003;278:28523-28527.
    • (2003) J. Biol. Chem. , vol.278 , pp. 28523-28527
    • Genth, H.1    Gerhard, R.2    Maeda, A.3    Amano, M.4    Kaibuchi, K.5    Aktories, K.6    Just, I.7
  • 58
    • 0032831781 scopus 로고    scopus 로고
    • Monoglucosylation of RhoA at threonine 37 blocks cytosol-membrane cycling
    • Genth H, Aktories K, Just I. Monoglucosylation of RhoA at threonine 37 blocks cytosol-membrane cycling. J Biol Chem 1999;274:29050-29056.
    • (1999) J. Biol. Chem. , vol.274 , pp. 29050-29056
    • Genth, H.1    Aktories, K.2    Just, I.3
  • 60
    • 5644229545 scopus 로고    scopus 로고
    • ExoS Rho GTPase-activating protein activity stimulates reorganization of the actin cytoskeleton through Rho GTPase guanine nucleotide disassociation inhibitor
    • Sun J, Barbieri JT. ExoS Rho GTPase-activating protein activity stimulates reorganization of the actin cytoskeleton through Rho GTPase guanine nucleotide disassociation inhibitor. J Biol Chem 2004;279:42936-42944.
    • (2004) J. Biol. Chem. , vol.279 , pp. 42936-42944
    • Sun, J.1    Barbieri, J.T.2
  • 61
    • 0142157658 scopus 로고    scopus 로고
    • Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: Identification RS/DJ-1 RhoGDIalpha
    • MacKeigan JP, Clements CM, Lich JD, Pope RM, Hod Y, Ting JP. Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification RS/DJ-1 RhoGDIalpha. Cancer Res 2003;63:6928-6934.
    • (2003) Cancer Res. , vol.63 , pp. 6928-6934
    • MacKeigan, J.P.1    Clements, C.M.2    Lich, J.D.3    Pope, R.M.4    Hod, Y.5    Ting, J.P.6
  • 63
    • 2342560617 scopus 로고    scopus 로고
    • Overexpression of autocrine motility factor in metastatic tumor cells: Possible association with augmented expression of KIF3A and GDI-beta
    • Yanagawa T, Watanabe H, Takeuchi T, Fujimoto S, Kurihara H, Takagishi K. Overexpression of autocrine motility factor in metastatic tumor cells: possible association with augmented expression of KIF3A and GDI-beta. Lab Invest 2004;84:513-522.
    • (2004) Lab. Invest. , vol.84 , pp. 513-522
    • Yanagawa, T.1    Watanabe, H.2    Takeuchi, T.3    Fujimoto, S.4    Kurihara, H.5    Takagishi, K.6
  • 65
    • 0034842795 scopus 로고    scopus 로고
    • The relationship of BRMS1 and RhoGDI2 gene expression to metastatic potential in lineage related human bladder cancer cell lines
    • Seraj MJ, Harding MA, Gildea JJ, Welch DR, Theodorescu D. The relationship of BRMS1 and RhoGDI2 gene expression to metastatic potential in lineage related human bladder cancer cell lines. Clin Exp Metastasis 2000;18:519-525.
    • (2000) Clin. Exp. Metastasis , vol.18 , pp. 519-525
    • Seraj, M.J.1    Harding, M.A.2    Gildea, J.J.3    Welch, D.R.4    Theodorescu, D.5
  • 67
    • 0347379871 scopus 로고    scopus 로고
    • Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling
    • Matos P, Collard JG, Jordan P. Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling. J Biol Chem 2003;278:50442-50448.
    • (2003) J. Biol. Chem. , vol.278 , pp. 50442-50448
    • Matos, P.1    Collard, J.G.2    Jordan, P.3
  • 68
    • 11244313840 scopus 로고    scopus 로고
    • Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation
    • Singh A, Karnoub AE, Palmby TR, Lengyel E, Sondek J, Der CJ. Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation. Oncogene 2004;23:9369-9380.
    • (2004) Oncogene , vol.23 , pp. 9369-9380
    • Singh, A.1    Karnoub, A.E.2    Palmby, T.R.3    Lengyel, E.4    Sondek, J.5    Der, C.J.6
  • 69
    • 14644420930 scopus 로고    scopus 로고
    • Interfacial inhibition of macromolecular interactions: Nature's paradigm for drug discovery
    • Pommier Y, Cherfils J. Interfacial inhibition of macromolecular interactions: nature's paradigm for drug discovery. Trends Pharmacol Sci 2005;26:138-145.
    • (2005) Trends Pharmacol. Sci. , vol.26 , pp. 138-145
    • Pommier, Y.1    Cherfils, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.