메뉴 건너뛰기




Volumn 1387, Issue , 2011, Pages 1-7

Role of p115RhoGEF in lipopolysaccharide-induced mouse brain microvascular endothelial barrier dysfunction

Author keywords

Endothelial cell; Rho; RhoGEFs; Tight junction

Indexed keywords

BETA ACTIN; CLAUDIN 5; EXOENZYME C3; F ACTIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; LIPOPOLYSACCHARIDE; OCCLUDIN; PHALLOIDIN; PROTEIN P115RHOGEF; PROTEIN ZO1; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHODAMINE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 79954420343     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.02.059     Document Type: Article
Times cited : (29)

References (27)
  • 1
    • 0037908673 scopus 로고    scopus 로고
    • 13-dependent plasma membrane recruitment of p115RhoGEF
    • DOI 10.1042/BJ20021897
    • R. Bhattacharyya, and P.B. Wedegaertner Characterization of G alpha 13-dependent plasma membrane recruitment of p115RhoGEF Biochem. J. 371 2003 709 720 (Pubitemid 36578870)
    • (2003) Biochemical Journal , vol.371 , Issue.3 , pp. 709-720
    • Bhattacharyya, R.1    Wedegaertner, P.B.2
  • 4
    • 73149087504 scopus 로고    scopus 로고
    • Disruptions of occludin and claudin-5 in brain endothelial cells in vitro and in brains of mice with acute liver failure
    • F. Chen, N. Ohashi, W. Li, C. Eckman, and J.H. Nguyen Disruptions of occludin and claudin-5 in brain endothelial cells in vitro and in brains of mice with acute liver failure Hepatology 50 2009 1914 1923
    • (2009) Hepatology , vol.50 , pp. 1914-1923
    • Chen, F.1    Ohashi, N.2    Li, W.3    Eckman, C.4    Nguyen, J.H.5
  • 5
    • 12144253807 scopus 로고    scopus 로고
    • RhoA and Rho-kinase dependent and independent signals mediate TGF-beta-induced pulmonary endothelial cytoskeletal reorganization and permeability
    • R.T. Clements, F.L. Minnear, H.A. Singer, R.S. Keller, and P.A. Vincent RhoA and Rho-kinase dependent and independent signals mediate TGF-beta-induced pulmonary endothelial cytoskeletal reorganization and permeability Am. J. Physiol. Lung Cell. Mol. Physiol. 288 2005 L294 L306
    • (2005) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.288
    • Clements, R.T.1    Minnear, F.L.2    Singer, H.A.3    Keller, R.S.4    Vincent, P.A.5
  • 6
    • 0034660145 scopus 로고    scopus 로고
    • Cyclic amp blocks bacterial lipopolysaccharide-induced myosin light chain phosphorylation in endothelial cells through inhibition of Rho/Rho kinase signaling
    • M. Essler, J.M. Staddon, P.C. Weber, and M. Aepfelbacher Cyclic AMP blocks bacterial lipopolysaccharide-induced myosin light chain phosphorylation in endothelial cells through inhibition of Rho/Rho kinase signaling J. Immunol. 164 2000 6543 6549 (Pubitemid 30408840)
    • (2000) Journal of Immunology , vol.164 , Issue.12 , pp. 6543-6549
    • Essler, M.1    Staddon, J.M.2    Weber, P.C.3    Aepfelbacher, M.4
  • 7
    • 0034711449 scopus 로고    scopus 로고
    • Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G (12) family to Rho
    • S. Fukuhara, H. Chikumi, and J.S. Gutkind Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G (12) family to Rho FEBS Lett. 485 2000 183 188
    • (2000) FEBS Lett. , vol.485 , pp. 183-188
    • Fukuhara, S.1    Chikumi, H.2    Gutkind, J.S.3
  • 8
    • 0033605294 scopus 로고    scopus 로고
    • A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho
    • DOI 10.1074/jbc.274.9.5868
    • S. Fukuhara, C. Murga, M. Zohar, T. Igishi, and J.S. Gutkind A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho J. Biol. Chem. 274 1999 5868 5879 (Pubitemid 29109244)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.9 , pp. 5868-5879
    • Fukuhara, S.1    Murga, C.2    Zohar, M.3    Igishi, T.4    Gutkind, J.S.5
  • 9
    • 0027445309 scopus 로고
    • Bacterial lipopolysaccharide induces actin reorganization, intercellular gap formation, and endothelial barrier dysfunction in pulmonary vascular endothelial cells: Concurrent F-actin depolymerization and new actin synthesis
    • DOI 10.1002/jcp.1041570103
    • S.E. Goldblum, X. Ding, T.W. Brann, and J. Campbell-Washington Bacterial lipopolysaccharide induces actin reorganization, intercellular gap formation, and endothelial barrier dysfunction in pulmonary vascular endothelial cells: concurrent F-actin depolymerization and new actin synthesis J. Cell. Physiol. 157 1993 13 23 (Pubitemid 23300657)
    • (1993) Journal of Cellular Physiology , vol.157 , Issue.1 , pp. 13-23
    • Goldblum, S.E.1    Ding, X.2    Brann, T.W.3    Campbell-Washington, J.4
  • 10
    • 0034918411 scopus 로고    scopus 로고
    • The endothelium in sepsis: Source of and a target for inflammation
    • C.E. Hack, and S. Zeerleder The endothelium in sepsis: source of and a target for inflammation Crit. Care Med. 29 2001 S21 S27
    • (2001) Crit. Care Med. , vol.29
    • Hack, C.E.1    Zeerleder, S.2
  • 11
    • 0020570576 scopus 로고
    • Lipopolysaccharide-mediated bovine endothelial cell injury in vitro
    • J.M. Harlan, L.A. Harker, M.A. Reidy, C.M. Gajdusek, S.M. Schwartz, and G.E. Striker Lipopolysaccharide-mediated bovine endothelial cell injury in vitro Lab. Invest. 48 1983 269 274 (Pubitemid 13110822)
    • (1983) Laboratory Investigation , vol.48 , Issue.3 , pp. 269-274
    • Harlan, J.M.1    Harker, L.A.2    Reidy, M.A.3
  • 14
    • 0034658332 scopus 로고    scopus 로고
    • Rho proteins and the p38-MAPK pathway are important mediators for LPS- induced interleukin-8 expression in human endothelial cells
    • S. Hippenstiel, S. Soeth, B. Kellas, O. Fuhrmann, J. Seybold, M. Krull, C. Eichel-Streiber, M. Goebeler, S. Ludwig, and N. Suttorp Rho proteins and the p38-MAPK pathway are important mediators for LPS-induced interleukin-8 expression in human endothelial cells Blood 95 2000 3044 3051 (Pubitemid 30321152)
    • (2000) Blood , vol.95 , Issue.10 , pp. 3044-3051
    • Hippenstiel, S.1    Soeth, S.2    Kellas, B.3    Fuhrmann, O.4    Seybold, J.5    Krull, M.6    Eichel-Streiber, C.7    Goebeler, M.8    Ludwig, S.9    Suttorp, N.10
  • 15
    • 0043237427 scopus 로고    scopus 로고
    • Protein kinase Cα-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement
    • DOI 10.1074/jbc.M303900200
    • M. Holinstat, D. Mehta, T. Kozasa, R.D. Minshall, and A.B. Malik Protein kinase Calpha-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement J. Biol. Chem. 278 2003 28793 28798 (Pubitemid 36935789)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.31 , pp. 28793-28798
    • Holinstat, M.1    Mehta, D.2    Kozasa, T.3    Minshall, R.D.4    Malik, A.B.5
  • 16
    • 14244257768 scopus 로고    scopus 로고
    • Hydrogen peroxide-induced alterations of tight junction proteins in bovine brain microvascular endothelial cells
    • DOI 10.1016/j.mvr.2004.07.005
    • H.S. Lee, K. Namkoong, D.H. Kim, K.J. Kim, Y.H. Cheong, S.S. Kim, W.B. Lee, and K.Y. Kim Hydrogen peroxide-induced alterations of tight junction proteins in bovine brain microvascular endothelial cells Microvasc. Res. 68 2004 231 238 (Pubitemid 40288119)
    • (2004) Microvascular Research , vol.68 , Issue.3 , pp. 231-238
    • Lee, H.-S.1    Namkoong, K.2    Kim, D.-H.3    Kim, K.-J.4    Cheong, Y.-H.5    Kim, S.-S.6    Lee, W.-B.7    Kim, K.-Y.8
  • 17
    • 0032507698 scopus 로고    scopus 로고
    • Effect of lipopolysaccharide on the permeability and reactivity of the cerebral microcirculation: Role of inducible nitric oxide synthase
    • DOI 10.1016/S0006-8993(98)00259-5, PII S0006899398002595
    • W.G. Mayhan Effect of lipopolysaccharide on the permeability and reactivity of the cerebral microcirculation: role of inducible nitric oxide synthase Brain Res. 792 1998 353 357 (Pubitemid 28267554)
    • (1998) Brain Research , vol.792 , Issue.2 , pp. 353-357
    • Mayhan, W.G.1
  • 19
    • 53749096762 scopus 로고    scopus 로고
    • Blood-brain barrier tight junction permeability and ischemic stroke
    • K.E. Sandoval, and K.A. Witt Blood-brain barrier tight junction permeability and ischemic stroke Neurobiol. Dis. 32 2008 200 219
    • (2008) Neurobiol. Dis. , vol.32 , pp. 200-219
    • Sandoval, K.E.1    Witt, K.A.2
  • 20
    • 34547096543 scopus 로고    scopus 로고
    • Lipopolysaccharide disrupts tight junctions in cholangiocyte monolayers by a c-Src-, TLR4-, and LBP-dependent mechanism
    • P. Sheth, N. Delos Santos, A. Seth, N.F. LaRusso, and R.K. Rao Lipopolysaccharide disrupts tight junctions in cholangiocyte monolayers by a c-Src-, TLR4-, and LBP-dependent mechanism Am. J. Physiol. Gastrointest. Liver Physiol. 293 2007 G308 G318
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.293
    • Sheth, P.1    Delos Santos, N.2    Seth, A.3    Larusso, N.F.4    Rao, R.K.5
  • 23
    • 3142730924 scopus 로고    scopus 로고
    • Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells
    • DOI 10.1074/jbc.C400105200
    • Q. Wang, M. Liu, T. Kozasa, J.D. Rothstein, P.C. Sternweis, and R.R. Neubig Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells J. Biol. Chem. 279 2004 28831 28834 (Pubitemid 38915749)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.28 , pp. 28831-28834
    • Wang, Q.1    Liu, M.2    Kozasa, T.3    Rothstein, J.D.4    Sternweis, P.C.5    Neubig, R.R.6
  • 24
    • 0035800854 scopus 로고    scopus 로고
    • Identification of potential mechanisms for regulation of p115 RhoGEF through analysis of endogenous and mutant forms of the exchange factor
    • C.D. Wells, S. Gutowski, G. Bollag, and P.C. Sternweis Identification of potential mechanisms for regulation of p115 RhoGEF through analysis of endogenous and mutant forms of the exchange factor J. Biol. Chem. 276 2001 28897 28905
    • (2001) J. Biol. Chem. , vol.276 , pp. 28897-28905
    • Wells, C.D.1    Gutowski, S.2    Bollag, G.3    Sternweis, P.C.4
  • 26
    • 0042344706 scopus 로고    scopus 로고
    • Rho GTPases and the regulation of endothelial permeability
    • DOI 10.1016/S1537-1891(03)00008-9
    • B. Wojciak-Stothard, and A.J. Ridley Rho GTPases and the regulation of endothelial permeability Vascul. Pharmacol. 39 2002 187 199 (Pubitemid 37492962)
    • (2002) Vascular Pharmacology , vol.39 , Issue.4-5 , pp. 187-199
    • Wojciak-Stothard, B.1    Ridley, A.J.2
  • 27
    • 0036627211 scopus 로고    scopus 로고
    • Tight junctions of the blood-brain barrier: Development, composition and regulation
    • DOI 10.1016/S1537-1891(02)00200-8, PII S1537189102002008
    • H. Wolburg, and A. Lippoldt Tight junctions of the blood-brain barrier: development, composition and regulation Vascul. Pharmacol. 38 2002 323 337 (Pubitemid 36398254)
    • (2002) Vascular Pharmacology , vol.38 , Issue.6 , pp. 323-337
    • Wolburg, H.1    Lippoldt, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.