Is the mechanical activity of epithelial cells controlled by deformations or forces?

Biophysical Journal

Volumn 89, Issue 6, 2005, Pages

  Saez, Alexandre ^a   Buguin, Axel ^b   Silberzan, Pascal ^b   Ladoux, Benoît ^a  

^a UNIVERSITÉ PARIS DIDEROT   (France)

^b INSTITUT CURIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT DYE;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL SHAPE; CELL STRAIN; EPITHELIUM CELL; FORCE; IMMUNOFLUORESCENCE; MONOLAYER CULTURE; NONHUMAN; QUANTITATIVE ANALYSIS; RIGIDITY; SCANNING ELECTRON MICROSCOPY; SENSOR;

ANIMALIA;

EID: 28444491145     PISSN: 00063495     EISSN: 00063495     Source Type: Journal    
DOI: 10.1529/biophysj.105.071217     Document Type: Article

References (11)

1. Choquet, D., D. P. Felsenfeld, and M. P. Sheetz. 1997. Extracellular matrix rigidity causes strengthening of integrin-cytoskeletal linkages. Cell. 88:39-48.
2. Galbraith, C. G., and M. P. Sheetz. 1997. A micromachined device provides a new bend on fibroblast traction forces. Proc. Natl. Acad. Sci. USA 94:9114-9118.
3. Dembo, M., and Y.-L. Wang. 1999. Stresses at the cell-to-substrate interface during locomotion of fibroblasts. Biophys. J. 76:2307-2316.
4. Balaban, N. Q., U. S. Schwartz, D. Riveline, P. Goichberg, G. Tzur, I. Sabanay, D. Mahalu, S. Safran, A. Bershadsky, L. Addadi, and B. Geiger. 2001. Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates. Nat. Cell Biol. 3:466-472.
5. Butler, J. P., I. M. Tolic-Norrelykke, B. Fabry, and J. J. Fredberg. 2002. Traction fields, moments, and strain energy that cells exert on their surroundings. Am. J. Physiol. Cell Physiol. 282:C595-C605.
6. Tan, J. L., J. Tien, D. M. Pirone, D. S. Gray, K. Bhadriraju, and C. S. Chen. 2003. Cells lying on a bed of microneedles: an approach to isolate mechanical forces. Proc. Natl. Acad. Sci. USA. 100:1484-1489.
7. Lo, C. M., H. B. Wang, M. Dembo, and Y.-L. Wang. 2000. Cell movement is guided by the rigidity of the substrate. Biophys. J. 79:144-152.
8. Pelham, R. J., and Y.-L. Wang. 1997. Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc. Natl. Acad. Sci. USA. 94:13661-13665.
9. Yeug, T., P. C. Georges, L. A. Flanagan, B. Marg, M. Ortiz, M. Funaki, N. Zahir, W. Ming, V. Weaver, and P. A. Janmey. 2005. Effects of substrate stiffness on cell morphology, cytoskeletal structure and adhesion. Cell Motil. Cytoskeleton. 60:24-34.
10. du Roure, O., A. Saez, R. H. Austin, A. Buguin, P. Chavrier, P. Silberzan, and B. Ladoux. 2005. Force mapping in epithelial cell migration. Proc. Natl. Acad. Sci. USA. 102:2390-2395.
11. Landau, L., and E. Lifschitz. 1990. Théorie de l'élasticité, 2nd Ed. M.I.R., Moscow, Russia.