메뉴 건너뛰기




Volumn 6, Issue 4, 2014, Pages 541-561

Lipidomics of Alzheimer's disease

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN ANTIBODY; AMYLOID PRECURSOR PROTEIN; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; ANTIOXIDANT; APOLIPOPROTEIN E; CHOLINESTERASE INHIBITOR; FATTY ACID; GAMMA SECRETASE INHIBITOR; GLYCEROLIPID; GLYCEROPHOSPHOLIPID; LIPID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROLEPTIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; SPHINGOLIPID; STEROL; TAU PROTEIN;

EID: 84896897706     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.13.346     Document Type: Review
Times cited : (43)

References (146)
  • 1
    • 0000293742 scopus 로고
    • Über eine eigenartige Erkrankung der Hirnrinde
    • General Journal of Psychiatry and Psycho-Forensic Medicine
    • Alzheimer A. Über eine eigenartige Erkrankung der Hirnrinde. [About a peculiar disease of the cerebral cortex]. Allgemeine Zeitschrift für Psychiatrie und psychisch-gerichtliche Medizin 64, 146-148 (1907). General Journal of Psychiatry and Psycho-Forensic Medicine.
    • (1907) Allgemeine Zeitschrift für Psychiatrie und Psychisch-gerichtliche Medizin , vol.64 , pp. 146-148
    • Alzheimer, A.1
  • 2
    • 78751653622 scopus 로고    scopus 로고
    • National estimates of the prevalence of Alzheimer's disease in the United States
    • Brookmeyer R, Evans DA, Hebert L et al. National estimates of the prevalence of Alzheimer's disease in the United States. Alzheimers Dement. 7(1) 61-73 (2011).
    • (2011) Alzheimers Dement , vol.7 , Issue.1 , pp. 61-73
    • Brookmeyer, R.1    Evans, D.A.2    Hebert, L.3
  • 3
    • 33845948906 scopus 로고    scopus 로고
    • Mild cognitive impairment: Long-term course of four clinical subtypes
    • DOI 10.1212/01.wnl.0000249117.23318.e1, PII 0000611420061226000022
    • Busse A, Hensel A, Gühne U et al. Mild cognitive impairment: long-term course of four clinical subtypes. Neurology 67(12) 2176-2185 (2006). (Pubitemid 46035473)
    • (2006) Neurology , vol.67 , Issue.12 , pp. 2176-2185
    • Busse, A.1    Hensel, A.2    Guhne, U.3    Angermeyer, M.C.4    Riedel-Heller, S.G.5
  • 4
    • 84877046305 scopus 로고    scopus 로고
    • Cognitive approaches to early Alzheimer's disease diagnosis
    • Harrison J. Cognitive approaches to early Alzheimer's disease diagnosis. Med. Clin. North Am. 97(3) 425-438 (2013).
    • (2013) Med. Clin. North Am , vol.97 , Issue.3 , pp. 425-438
    • Harrison, J.1
  • 5
    • 84877074899 scopus 로고    scopus 로고
    • Relevance of magnetic resonance imaging for early detection and diagnosis of Alzheimer disease
    • Teipel SJ, Grothe M, Lista S et al. Relevance of magnetic resonance imaging for early detection and diagnosis of Alzheimer disease. Med. Clin. North Am. 97(3) 399-424 (2013).
    • (2013) Med. Clin. North Am , vol.97 , Issue.3 , pp. 399-424
    • Teipel, S.J.1    Grothe, M.2    Lista, S.3
  • 6
    • 84877022699 scopus 로고    scopus 로고
    • Amyloid imaging with PET in early Alzheimer disease diagnosis
    • Rowe CC, Villemagne VL. Amyloid imaging with PET in early Alzheimer disease diagnosis. Med. Clin. North Am. 97(3) 377-398 (2013).
    • (2013) Med. Clin. North Am , vol.97 , Issue.3 , pp. 377-398
    • Rowe, C.C.1    Villemagne, V.L.2
  • 7
    • 84877069816 scopus 로고    scopus 로고
    • The application of cerebrospinal fluid biomarkers in early diagnosis of Alzheimer disease
    • Blennow K, Zetterberg H. The application of cerebrospinal fluid biomarkers in early diagnosis of Alzheimer disease. Med. Clin. North Am. 97(3) 369-376 (2013).
    • (2013) Med. Clin. North Am , vol.97 , Issue.3 , pp. 369-376
    • Blennow, K.1    Zetterberg, H.2
  • 8
    • 67349143998 scopus 로고    scopus 로고
    • Classification and basic pathology of Alzheimer disease
    • Duyckaerts C, Delatour B, Potier MC. Classification and basic pathology of Alzheimer disease. Acta Neuropathol. 118(1), 5-36 (2009).
    • (2009) Acta Neuropathol , vol.118 , Issue.1 , pp. 5-36
    • Duyckaerts, C.1    Delatour, B.2    Potier, M.C.3
  • 9
    • 0026181928 scopus 로고
    • Processing of the Alzheimer's disease beta A4 amyloid precursor protein (APP)
    • Younkin SG. Processing of the Alzheimer's disease beta A4 amyloid precursor protein (APP). Brain Pathol. 1(4), 253-262 (1991).
    • (1991) Brain Pathol , vol.1 , Issue.4 , pp. 253-262
    • Younkin, S.G.1
  • 10
    • 33746310315 scopus 로고    scopus 로고
    • Alzheimer's disease
    • DOI 10.1016/S0140-6736(06)69113-7, PII S0140673606691137
    • Blennow K, de Leon MJ, Zetterberg H. Alzheimer's disease. Lancet 368(9533), 387-403 (2006). (Pubitemid 44108123)
    • (2006) Lancet , vol.368 , Issue.9533 , pp. 387-403
    • Blennow, K.1    De Leon, M.J.2    Zetterberg, H.3
  • 11
    • 0037411517 scopus 로고    scopus 로고
    • A grading system of Alzheimer disease lesions in neocortical areas
    • DOI 10.1016/S0197-4580(02)00134-3, PII S0197458002001343
    • Metsaars WP, Hauw JJ, van Welse ME et al. A grading system of Alzheimer disease lesions in neocortical areas. Neurobiol. Aging 24(4), 563-572 (2003). (Pubitemid 36513704)
    • (2003) Neurobiology of Aging , vol.24 , Issue.4 , pp. 563-572
    • Metsaars, W.P.1    Hauw, J.-J.2    Van Welsem, M.E.3    Duyckaerts, C.4
  • 13
    • 0026740795 scopus 로고
    • Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
    • Arriagada PV, Growdon JH, Hedley-Whyte ET et al. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 42(3 Pt 1), 631-639 (1992).
    • (1992) Neurology , vol.42 , Issue.3 PART 1 , pp. 631-639
    • Arriagada, P.V.1    Growdon, J.H.2    Hedley-Whyte, E.T.3
  • 14
    • 0025863618 scopus 로고
    • Neuropathological staging of Alzheimer-related changes
    • Braak H, Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol. 82(4), 239-259 (1991).
    • (1991) Acta Neuropathol , vol.82 , Issue.4 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 15
    • 46749097518 scopus 로고    scopus 로고
    • Inhibition and Modulation of γ-Secretase for Alzheimer's Disease
    • DOI 10.1016/j.nurt.2008.05.010, PII S1933721308000986
    • Wolfe MS. Inhibition and modulation of gamma-secretase for Alzheimer's disease. Neurotherapeutics 5(3), 391-398 (2008). (Pubitemid 351952492)
    • (2008) Neurotherapeutics , vol.5 , Issue.3 , pp. 391-398
    • Wolfe, M.S.1
  • 16
    • 33750156019 scopus 로고    scopus 로고
    • α-Secretase activation - An approach to Alzheimer's disease therapy
    • DOI 10.1159/000095264
    • Fahrenholz F, Postina R. Alpha-secretase activation - an approach to Alzheimer's disease therapy. Neurodegener. Dis. 3(4-5), 255-261 (2006). (Pubitemid 44600312)
    • (2006) Neurodegenerative Diseases , vol.3 , Issue.4-5 , pp. 255-261
    • Fahrenholz, F.1    Postina, R.2
  • 17
    • 58149375748 scopus 로고    scopus 로고
    • Anti-Ab immunotherapy in Alzheimer's disease; Relevance of transgenic mouse studies to clinical trials
    • Wilcock DM, Colton CA. Anti-Ab immunotherapy in Alzheimer's disease; relevance of transgenic mouse studies to clinical trials. J. Alzheimers Dis. 15(4), 555-569 (2008).
    • (2008) J. Alzheimers Dis , vol.15 , Issue.4 , pp. 555-569
    • Wilcock, D.M.1    Colton, C.A.2
  • 18
    • 80054843547 scopus 로고    scopus 로고
    • Associations of anti-hypertensive treatments with Alzheimer's disease, vascular dementia, and other dementias
    • Davies NM, Kehoe PG, Ben-Shlomo Y et al. Associations of anti-hypertensive treatments with Alzheimer's disease, vascular dementia, and other dementias. J. Alzheimers Dis. 26(4), 699-708 (2011).
    • (2011) J. Alzheimers Dis , vol.26 , Issue.4 , pp. 699-708
    • Davies, N.M.1    Kehoe, P.G.2    Ben-Shlomo, Y.3
  • 19
    • 7244226629 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: Old and new mechanisms of action
    • DOI 10.1111/j.1471-4159.2004.02743.x
    • Gasparini L, Ongini E, Wenk G. Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action. J. Neurochem. 91(3), 521-536 (2004). (Pubitemid 39431148)
    • (2004) Journal of Neurochemistry , vol.91 , Issue.3 , pp. 521-536
    • Gasparini, L.1    Ongini, E.2    Wenk, G.3
  • 20
    • 84863798026 scopus 로고    scopus 로고
    • Antioxidants for Alzheimer disease: A randomized clinical trial with cerebrospinal fluid biomarker measures
    • Galasko DR, Peskind E, Clark CM et al. Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures. Arch. Neurol. 69(7) 836-841 (2012).
    • (2012) Arch. Neurol , vol.69 , Issue.7 , pp. 836-841
    • Galasko, D.R.1    Peskind, E.2    Clark, C.M.3
  • 21
    • 2442489033 scopus 로고    scopus 로고
    • Relation of plasma lipids to alzheimer disease and vascular dementia
    • DOI 10.1001/archneur.61.5.705
    • Reitz C, Tang MX, Luchsinger J et al. Relation of plasma lipids to Alzheimer disease and vascular dementia. Arch. Neurol. 61(5) 705-714 (2004). (Pubitemid 38637688)
    • (2004) Archives of Neurology , vol.61 , Issue.5 , pp. 705-714
    • Reitz, C.1    Tang, M.-X.2    Luchsinger, J.3    Mayeux, R.4
  • 22
    • 36949016215 scopus 로고    scopus 로고
    • Alzheimer disease models and human neuropathology: Similarities and differences
    • DOI 10.1007/s00401-007-0312-8
    • Duyckaerts C, Potier MC, Delatour B. Alzheimer disease models and human neuropathology:similarities and differences. Acta Neuropathol. 115(1), 5-38 (2008). (Pubitemid 50005258)
    • (2008) Acta Neuropathologica , vol.115 , Issue.1 , pp. 5-38
    • Duyckaerts, C.1    Potier, M.-C.2    Delatour, B.3
  • 23
  • 24
    • 34347353311 scopus 로고    scopus 로고
    • Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1
    • DOI 10.1523/JNEUROSCI.4272-06.2007
    • Lazarov O, Morfini GA, Pigino G et al. Impairments infast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin1. J. Neurosci. 27(26), 7011-7020 (2007). (Pubitemid 47015908)
    • (2007) Journal of Neuroscience , vol.27 , Issue.26 , pp. 7011-7020
    • Lazarov, O.1    Morfini, G.A.2    Pigino, G.3    Gadadhar, A.4    Chen, X.5    Robinson, J.6    Ho, H.7    Brady, S.T.8    Sisodia, S.S.9
  • 25
    • 7244234177 scopus 로고    scopus 로고
    • β-Site amyloid precursor protein cleaving enzyme 1 increases amyloid deposition in brain parenchyma but reduces cerebrovascular amyloid angiopathy in aging BACE x APP[V717I] double-transgenic mice
    • Willem M, Dewachter I, Smyth N et al. Beta-site amyloid precursor proteincleaving enzyme 1 increases amyloid deposition in brainparenchyma but reduces cerebrovascular amyloid angiopathy inaging BACE × APP[V717I] double-transgenic mice. Am. J. Pathol. 165(5), 1621-1631 (2004). (Pubitemid 39435161)
    • (2004) American Journal of Pathology , vol.165 , Issue.5 , pp. 1621-1631
    • Willem, M.1    Dewachter, I.2    Smyth, N.3    Van Dooren, T.4    Borghgraef, P.5    Haass, C.6    Van Leuven, F.7
  • 26
    • 25444479179 scopus 로고    scopus 로고
    • High β-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-β levels: Implications for the treatment of Alzheimer disease
    • DOI 10.1074/jbc.M507016200
    • Rockenstein E, Mante M, Alford M et al. High beta secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels: implications for the treatment of Alzheimer disease. J. Biol. Chem. 280(38), 32957-32967 (2005). (Pubitemid 41368345)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.38 , pp. 32957-32967
    • Rockenstein, E.1    Mante, M.2    Alford, M.3    Adame, A.4    Crews, L.5    Hashimoto, M.6    Esposito, L.7    Mucke, L.8    Masliah, E.9
  • 28
    • 1642578930 scopus 로고    scopus 로고
    • Characterisation of cytoskeletal abnormalities in mice transgenic for wild-type human tau and familial Alzheimer's disease mutants of APP and presenilin-1
    • DOI 10.1016/j.nbd.2003.09.007
    • Boutajangout A, Authelet M, Blanchard V et al. Characterisation of cytoskeletal abnormalities in mice transgenic for wild type human tau and familial Alzheimer's disease mutants of APP and presenilin-1. Neurobiol. Dis. 15(1), 47-60 (2004). (Pubitemid 38134380)
    • (2004) Neurobiology of Disease , vol.15 , Issue.1 , pp. 47-60
    • Boutajangout, A.1    Authelet, M.2    Blanchard, V.3    Touchet, N.4    Tremp, G.5    Pradier, L.6    Brion, J.-P.7
  • 29
  • 30
    • 0041387451 scopus 로고    scopus 로고
    • Analysis of phosphatidylcholine and sphingomyelin molecular species from brain extracts using capillary liquid chromatography electrospray ionization mass spectrometry
    • DOI 10.1016/S0165-0270(03)00168-7
    • Isaac G, Bylund D, Månsson JE et al. Analysis of phosphatidyl choline and sphingomyelin molecular species from brain extracts using capillary LC-ESI-MS. J. Neurosci. Methods 128(1-2), 111-119 (2003). (Pubitemid 37013555)
    • (2003) Journal of Neuroscience Methods , vol.128 , Issue.1-2 , pp. 111-119
    • Isaac, G.1    Bylund, D.2    Mansson, J.-E.3    Markides, K.E.4    Bergquist, J.5
  • 31
    • 0034669579 scopus 로고    scopus 로고
    • Supercritical carbon dioxide extraction of phospholipids from dried egg yolk without organic modifier
    • Boselli E, Caboni MF. Supercritical carbon dioxide extraction of phospholipids from dried egg yolk without organic modifier. J. Supercritical Fluids 19(1), 45-50 (2000).
    • (2000) J. Supercritical Fluids , vol.19 , Issue.1 , pp. 45-50
    • Boselli, E.1    Caboni, M.F.2
  • 32
    • 47749096683 scopus 로고    scopus 로고
    • Determination of intramuscular PL classes and molecular species in Gaoyou duck
    • Daoying W, Weimin X, Xinglian X et al. Determination of intramuscular PL classes and molecular species in Gaoyou duck. Food Chem. 112(1), 150-155 (2009).
    • (2009) Food Chem , vol.112 , Issue.1 , pp. 150-155
    • Daoying, W.1    Weimin, X.2    Xinglian, X.3
  • 33
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226(1), 457-509 (1957).
    • (1957) J. Biol. Chem , vol.226 , Issue.1 , pp. 457-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 34
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37(8), 911-917 (1959).
    • (1959) Can. J. Biochem. Physiol , vol.37 , Issue.8 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 35
    • 50049102248 scopus 로고    scopus 로고
    • Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics
    • Matyash V, Liebisch G, Kurzchalia TV et al. Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics. J. Lipid Res. 49(5), 1137-1146 (2008). • New lipid extraction method gaining popularity.
    • (2008) J. Lipid Res , vol.49 , Issue.5 , pp. 1137-1146
    • Matyash, V.1    Liebisch, G.2    Kurzchalia, T.V.3
  • 36
    • 36749025314 scopus 로고    scopus 로고
    • Lipidomics: Practical aspects and applications
    • DOI 10.1016/j.plipres.2007.09.001, PII S0163782707000422
    • Wolf C, Quinn PJ. Lipidomics: practical aspects and applications. Prog. Lipid Res. 47(1), 15-36 (2008). (Pubitemid 350216620)
    • (2008) Progress in Lipid Research , vol.47 , Issue.1 , pp. 15-36
    • Wolf, C.1    Quinn, P.J.2
  • 37
    • 0029099850 scopus 로고
    • Thin-layer chromatographic procedures for lipid separation
    • Touchstone JC. Thin-layer chromatographic procedures for lipid separation. J. Chromatogr. B 671, 169-195 (1995).
    • (1995) J. Chromatogr. B , vol.671 , pp. 169-195
    • Touchstone, J.C.1
  • 38
    • 79954629646 scopus 로고    scopus 로고
    • Lipid analysis by thin-layer chromatography - A review of the current state
    • Fuchs B, Süb R, Teuber K et al. Lipid analysis by thin-layer chromatography - a review of the current state. J. Chromatogr. A 1218(19), 2754-2774 (2011).
    • (2011) J. Chromatogr. A , vol.1218 , Issue.19 , pp. 2754-2774
    • Fuchs, B.1    Süb, R.2    Teuber, K.3
  • 40
    • 0029132209 scopus 로고
    • Fatty acid lipid profiles
    • Gutnikov G. Fatty acid lipid profiles. J. Chromatogr. B 671(1-2), 71-89 (1995).
    • (1995) J. Chromatogr. B , vol.671 , Issue.1-2 , pp. 71-89
    • Gutnikov, G.1
  • 41
    • 0000408332 scopus 로고
    • Dimethoxypropane induced transesterification of fats and oils in preparation of methyl esters for gas chromatographic analysis
    • Masson ME, Waller GR. Dimethoxypropane induced transesterification of fats and oils in preparation of methyl esters for gas chromatographic analysis. Anal. Chem. 36(3) 583-586 (1964).
    • (1964) Anal. Chem , vol.36 , Issue.3 , pp. 583-586
    • Masson, M.E.1    Waller, G.R.2
  • 42
    • 70350492887 scopus 로고    scopus 로고
    • Linear quadrupoles in mass spectrometry
    • Douglas DJ. Linear quadrupoles in mass spectrometry. Mass Spectrom. Rev. 28(6), 937-960 (2009).
    • (2009) Mass Spectrom. Rev , vol.28 , Issue.6 , pp. 937-960
    • Douglas, D.J.1
  • 43
    • 30144440147 scopus 로고    scopus 로고
    • Tandem time-of-flight mass spectrometry
    • DOI 10.1016/S0076-6879(05)02001-X, PII S0076687905020033, 3, Biological Mass Spectrometry
    • Vestal ML, Campbell JM. Tandem time-of-flight mass spectrometry. Meth. Enzymol. 402, 79-108 (2005). (Pubitemid 43053126)
    • (2005) Methods in Enzymology , vol.402 , pp. 79-108
    • Vestal, M.L.1    Campbell, J.M.2
  • 44
    • 18344393519 scopus 로고    scopus 로고
    • Shotgun lipidomics: Electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples
    • DOI 10.1002/mas.20023
    • Han X, Gross RW. Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples. Mass Spectrom. Rev. 24(3), 367-412 (2005). (Pubitemid 40665798)
    • (2005) Mass Spectrometry Reviews , vol.24 , Issue.3 , pp. 367-412
    • Han, X.1    Gross, R.W.2
  • 45
    • 24644477568 scopus 로고
    • Matrix-assisted ultraviolet laser desorption of non-volatile compounds
    • Karas M, Bachman D, Bahr U et al. Matrix-assisted ultraviolet laser desorption of non-volatile compounds. Int. J. Mass Spectrom. Ion Proc. 78, 53-68 (1987).
    • (1987) Int. J. Mass Spectrom. Ion Proc , vol.78 , pp. 53-68
    • Karas, M.1    Bachman, D.2    Bahr, U.3
  • 46
    • 84984042980 scopus 로고
    • Protein and polymer analyses up to m/z 100 000 by laser ionization time-of flight mass spectrometry
    • Tanaka K, Waki H, Ido Y et al. Protein and polymer analyses up to m/z 100 000 by laser ionization time-of flight mass spectrometry. Rapid Commun. Mass Spectrom. 2(20), 151-153 (1988).
    • (1988) Rapid Commun. Mass Spectrom , vol.2 , Issue.20 , pp. 151-153
    • Tanaka, K.1    Waki, H.2    Ido, Y.3
  • 47
    • 0034194446 scopus 로고    scopus 로고
    • MALDI quadrupole time-of-flight mass spectrometry: A powerful tool for proteomic research
    • DOI 10.1021/ac9913659
    • Shevchenko A, Loboda A, Shevchenko A et al. MALDI quadrupole time-of-flight mass spectrometry: a powerful tool for proteomic research. Anal. Chem. 72(9), 2132-2141 (2000). (Pubitemid 30316592)
    • (2000) Analytical Chemistry , vol.72 , Issue.9 , pp. 2132-2141
    • Shevchenko, A.1    Loboda, A.2    Shevchenko, A.3    Ens, W.4    Standing, K.G.5
  • 48
    • 58149296564 scopus 로고    scopus 로고
    • MALDI-TOF MS analysis of lipids from cells, tissues and body fluids
    • Fuchs B, Schiller J. MALDI-TOF MS analysis of lipids from cells, tissues and body fluids. Subcell. Biochem. 49, 541-565 (2008).
    • (2008) Subcell. Biochem , vol.49 , pp. 541-565
    • Fuchs, B.1    Schiller, J.2
  • 49
    • 67849130973 scopus 로고    scopus 로고
    • High-throughput shotgun lipidomics by quadrupole time-of-flight mass spectrometry
    • Ståhlman M, Ejsing CS, Tarasov K et al. High-throughput shotgun lipidomics by quadrupole time-of-flight mass spectrometry. J. Chromatogr. B 877, 2664-2672(2009).
    • (2009) J. Chromatogr. B , vol.877 , pp. 2664-2672
    • Ståhlman, M.1    Ejsing, C.S.2    Tarasov, K.3
  • 50
    • 0003018911 scopus 로고
    • Electrospray ionization-principles and practice
    • Fenn JB, Mann M, Kai C et al. Electrospray ionization-principles and practice. Mass Spectrom. Rev. 9, 37-70 (1990).
    • (1990) Mass Spectrom. Rev , vol.9 , pp. 37-70
    • Fenn, J.B.1    Mann, M.2    Kai, C.3
  • 51
    • 67049116050 scopus 로고    scopus 로고
    • Improved separation and quantification of neutral and polar lipid classes by HPLC-ELSD using a monolithic silica phase: Application to exceptional marine lipids
    • Graeve M, Janssen DJ. Improved separation and quantification of neutral and polar lipid classes by HPLC-ELSD using a monolithic silica phase: application to exceptional marine lipids. Chromatogr. B Anal. Technol. Biomed. Life Sci. 877(20-21), 1815-1819 (2009).
    • (2009) Chromatogr. B Anal. Technol. Biomed. Life Sci , vol.877 , Issue.20-21 , pp. 1815-1819
    • Graeve, M.1    Janssen, D.J.2
  • 52
    • 84861201457 scopus 로고    scopus 로고
    • Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization for a lipidomic analysis of Leishmania donovani
    • Imbert L, Gaudin M, Libong L et al. Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization for a lipidomic analysis of Leishmania donovani. J. Chrom. A 1242, 75-83 (2012).
    • (2012) J. Chrom. A , vol.1242 , pp. 75-83
    • Imbert, L.1    Gaudin, M.2    Libong, L.3
  • 53
    • 33646532632 scopus 로고    scopus 로고
    • Liquid chromatography on porous graphitic carbon with atmospheric pressure photoionization mass spectrometry and tandem mass spectrometry for the analysis of glycosphingolipids
    • Roy S, Delobel A, Gaudin K et al. Liquid chromatography on porous graphitic carbon with atmospheric pressure photoionization mass spectrometry and tandem mass spectrometry for the analysis of glycosphingolipids. J. Chromatogr. A 1117, 154-162 (2006).
    • (2006) J. Chromatogr. A , vol.1117 , pp. 154-162
    • Roy, S.1    Delobel, A.2    Gaudin, K.3
  • 54
    • 84862508978 scopus 로고    scopus 로고
    • Atmospheric pressure photoionization as a powerfull tool for large-scale lipidomic studies
    • Gaudin M, Imbert L, Libong D et al. Atmospheric pressure photoionization as a powerfull tool for large-scale lipidomic studies. J. Am. Soc. Mass Spectrom. 23(5), 869-879 (2012).
    • (2012) J. Am. Soc. Mass Spectrom , vol.23 , Issue.5 , pp. 869-879
    • Gaudin, M.1    Imbert, L.2    Libong, D.3
  • 55
    • 54949084597 scopus 로고    scopus 로고
    • A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle
    • Laaksonen R, Katajamaa M, Päivä H et al. A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle. PLoS ONE 1, e97 (2006).
    • (2006) PLoS ONE , vol.1
    • Laaksonen, R.1    Katajamaa, M.2    Päivä, H.3
  • 56
    • 77953595299 scopus 로고    scopus 로고
    • Ultra performance liquid chromatography-mass spectrometry profiling of bile acid metabolites in biofluids: Application to experimental toxicology studies
    • Want EL, Coen M, Masson P et al. Ultra performance liquid chromatography-mass spectrometry profiling of bile acid metabolites in biofluids: application to experimental toxicology studies. Anal. Chem. 82(12), 5282-5289 (2010).
    • (2010) Anal. Chem , vol.82 , Issue.12 , pp. 5282-5289
    • Want, E.L.1    Coen, M.2    Masson, P.3
  • 57
    • 66749102638 scopus 로고    scopus 로고
    • Application of ultra performance liquid chromatography-mass spectrometry to profiling of rat and dog bile
    • Plumb RS, Rainville PD, Potts WB et al. Application of ultra performance liquid chromatography-mass spectrometry to profiling of rat and dog bile. J. Proteome Res. 8(5), 2495-2500 (2009).
    • (2009) J. Proteome Res , vol.8 , Issue.5 , pp. 2495-2500
    • Plumb, R.S.1    Rainville, P.D.2    Potts, W.B.3
  • 58
    • 72049111789 scopus 로고    scopus 로고
    • Rapid, simultaneous quantitation of mono and dioxygenated metabolites of arachidonic acid in human CSF and rat brain
    • Miller TM, Donnelly MK, Crago EA et al. Rapid, simultaneous quantitation of mono and dioxygenated metabolites of arachidonic acid in human CSF and rat brain. J. Chromatogr. B 877(31), 3991-4000 (2009).
    • (2009) J. Chromatogr. B , vol.877 , Issue.31 , pp. 3991-4000
    • Miller, T.M.1    Donnelly, M.K.2    Crago, E.A.3
  • 59
    • 79953301627 scopus 로고    scopus 로고
    • Method for liver tissue metabolic profiling study and its application in type 2 diabetic rats based on ultra performance liquid chromatography-mass spectrometry
    • Huang Q, Yin P, Wang J et al. Method for liver tissue metabolic profiling study and its application in type 2 diabetic rats based on ultra performance liquid chromatography-mass spectrometry. J. Chromatogr. B879(13-14), 961-967 (2011).
    • (2011) J. Chromatogr , vol.B879 , Issue.13-14 , pp. 961-967
    • Huang, Q.1    Yin, P.2    Wang, J.3
  • 60
    • 78149454125 scopus 로고    scopus 로고
    • Lipidomics era: Accomplishments and challenges
    • Bou Khalil M, Hou W, Zhou H et al. Lipidomics era: accomplishments and challenges. Mass Spectrom. Rev. 29(6), 877-929 (2010). •• Extensive review that should be read by any newcomer in lipidomics.
    • (2010) Mass Spectrom. Rev , vol.29 , Issue.6 , pp. 877-929
    • Bou Khalil, M.1    Hou, W.2    Zhou, H.3
  • 61
    • 57249091714 scopus 로고    scopus 로고
    • Orbitrap mass spectrometry: Instrumentation, ion motion and applications
    • Perry RH, Cooks RG, Noll RJ. Orbitrap mass spectrometry: instrumentation, ion motion and applications. Mass Spectrom. Rev. 27(6), 661-699 (2008).
    • (2008) Mass Spectrom. Rev , vol.27 , Issue.6 , pp. 661-699
    • Perry, R.H.1    Cooks, R.G.2    Noll, R.J.3
  • 62
    • 84870866676 scopus 로고    scopus 로고
    • Development of a novel method for quantification of sterols and oxysterols by UPLC-ESI-HRMS: Application to a neuroinflammation rat model
    • Ayciriex S, Regazzetti A, Gaudin M et al. Development of a novel method for quantification of sterols and oxysterols by UPLC-ESI-HRMS: application to a neuroinflammation rat model. Anal. BioAnal. Chem. 404(10), 3049-3059 (2012).
    • (2012) Anal. BioAnal. Chem , vol.404 , Issue.10 , pp. 3049-3059
    • Ayciriex, S.1    Regazzetti, A.2    Gaudin, M.3
  • 64
    • 79959232858 scopus 로고    scopus 로고
    • A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma
    • Jiang X, Sidhu R, Porter FD et al. A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma. J. Lipid Res. 52(7), 1435-1445 (2011).
    • (2011) J. Lipid Res , vol.52 , Issue.7 , pp. 1435-1445
    • Jiang, X.1    Sidhu, R.2    Porter, F.D.3
  • 66
    • 0018821962 scopus 로고
    • Krabbe disease: A galactosylsphingosine (psychosine) lipidosis
    • Svennerholm L, Vanier MT, Månsson JE. Krabbe disease: a galactosylsphingosine (psychosine) lipidosis. J. Lipid Res. 21(1), 53-64 (1980). (Pubitemid 10120438)
    • (1980) Journal of Lipid Research , vol.21 , Issue.1 , pp. 53-64
    • Svennerholm, L.1    Vanier, M.T.2    Mansson, J.E.3
  • 67
    • 80054841258 scopus 로고    scopus 로고
    • Elevated plasma glucosylsphingosine in Gaucher disease: Relation to phenotype, storage cell markers, and therapeutic response
    • Dekker N, van Dussen L, Hollak CE et al. Elevated plasma glucosylsphingosine in Gaucher disease: relation to phenotype, storage cell markers, and therapeutic response. Blood 118(16), e118-e127 (2011).
    • (2011) Blood , vol.118 , Issue.16
    • Dekker, N.1    Van Dussen, L.2    Hollak, C.E.3
  • 68
    • 84871288449 scopus 로고    scopus 로고
    • Lipid profiling for early diagnosis and progression of colorectal cancer using direct-infusion electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry
    • Li F, Qin X, Chen H et al. Lipid profiling for early diagnosis and progression of colorectal cancer using direct-infusion electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun. Mass Spectrom. 27(1), 24-34 (2013).
    • (2013) Rapid Commun. Mass Spectrom , vol.27 , Issue.1 , pp. 24-34
    • Li, F.1    Qin, X.2    Chen, H.3
  • 69
    • 80054713192 scopus 로고    scopus 로고
    • Real time analysis of brain tissue by direct combination of ultrasonic surgical aspiration and sonic spray mass spectrometry
    • Schäfer KC, Balog J, Szaniszló T et al. Real time analysis of brain tissue by direct combination of ultrasonic surgical aspiration and sonic spray mass spectrometry. Anal. Chem. 83(20), 7729-7735 (2011).
    • (2011) Anal. Chem , vol.83 , Issue.20 , pp. 7729-7735
    • Schäfer, K.C.1    Balog, J.2    Szaniszló, T.3
  • 70
    • 84857344913 scopus 로고    scopus 로고
    • Identifying the margin: A new method to distinguish between cancerous and noncancerous tissue during surgery
    • Takats Z, Denes J, Kinross J. Identifying the margin: a new method to distinguish between cancerous and noncancerous tissue during surgery. Future Oncol. 8(2), 113-116 (2012).
    • (2012) Future Oncol , vol.8 , Issue.2 , pp. 113-116
    • Takats, Z.1    Denes, J.2    Kinross, J.3
  • 71
    • 20444419500 scopus 로고    scopus 로고
    • A comprehensive classification system for lipids
    • Fahy E, Subramanian S, Brown HA et al. A comprehensive classification system for lipids. J. Lipid Res. 46(5), 839-861 (2005).
    • (2005) J. Lipid Res , vol.46 , Issue.5 , pp. 839-861
    • Fahy, E.1    Subramanian, S.2    Brown, H.A.3
  • 72
    • 66349098682 scopus 로고    scopus 로고
    • Update of the LIPID MAPS comprehensive classification system for lipids
    • Fahy E, Subramaniam S, Murphy RC et al. Update of the LIPID MAPS comprehensive classification system for lipids. J. Lipid Res. 50, S9-S14 (2009). •• Reference paper on lipid classification and nomenclature.
    • (2009) J. Lipid Res , vol.50
    • Fahy, E.1    Subramaniam, S.2    Murphy, R.C.3
  • 73
    • 3242701593 scopus 로고    scopus 로고
    • Cholesterol at the crossroads: Alzheimer's disease and lipid metabolism
    • DOI 10.1111/j.0009-9163.2004.00280.x
    • Wellington CL. Cholesterol at the crossroads: Alzheimer's disease and lipid metabolism. Clin. Genet. 66, 1-16 (2004). (Pubitemid 38960816)
    • (2004) Clinical Genetics , vol.66 , Issue.1 , pp. 1-16
    • Wellington, C.L.1
  • 75
    • 0028787064 scopus 로고
    • Influence of the apolipoprotein Egenotype on amyloid deposition and neurofibrillary tangle formation in Alzheimer's disease
    • Nagy Z, Esiri M, Jobst KA et al. Influence of the apolipoprotein Egenotype on amyloid deposition and neurofibrillary tangle formation in Alzheimer's disease. Neuroscience 69, 757-761 (1995).
    • (1995) Neuroscience , vol.69 , pp. 757-761
    • Nagy, Z.1    Esiri, M.2    Jobst, K.A.3
  • 78
    • 0025971426 scopus 로고
    • Apolipoprotein e immunoreactivity in cerebralamyloid deposits and neurofibrilliary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jacob disease
    • Namba Y, Tomonaga M, Kawasaki H et al. Apolipoprotein E immunoreactivity in cerebralamyloid deposits and neurofibrilliary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jacob disease. Brain Res. 541, 163-166 (1991).
    • (1991) Brain Res , vol.541 , pp. 163-166
    • Namba, Y.1    Tomonaga, M.2    Kawasaki, H.3
  • 79
    • 79959772357 scopus 로고    scopus 로고
    • Human apoE isoforms differentially regulate brain amyloid-{beta} peptide clearance
    • Castellano JM, Kim J, Stewart FR et al. Human apoE isoforms differentially regulate brain amyloid-{beta} peptide clearance. Sci. Transl. Med. 3, 89ra57 (2011).
    • (2011) Sci. Transl. Med , vol.3
    • Castellano, J.M.1    Kim, J.2    Stewart, F.R.3
  • 80
    • 0031278270 scopus 로고    scopus 로고
    • Lack of apolipoprotein e dramatically reduces amyloid beta-peptide deposition
    • Bales KR, Verina T, Dodel R. Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition. Nat. Genet. 17, 263-264 (1997).
    • (1997) Nat. Genet , vol.17 , pp. 263-264
    • Bales, K.R.1    Verina, T.2    Dodel, R.3
  • 81
    • 76849108962 scopus 로고    scopus 로고
    • Fatty acid composition of frontal, temporal and parietal neocortex in the normal human brain and in Alzheimer's disease
    • Fraser T, Tayler H, Love S. Fatty acid composition of frontal, temporal and parietal neocortex in the normal human brain and in Alzheimer's disease. Neurochem. Res. 35(3), 503-513 (2010).
    • (2010) Neurochem. Res , vol.35 , Issue.3 , pp. 503-513
    • Fraser, T.1    Tayler, H.2    Love, S.3
  • 82
    • 42649089790 scopus 로고    scopus 로고
    • Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators
    • DOI 10.1038/nri2294, PII NRI2294
    • Serhan CN, Chiang N, Van Dyke TE. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat. Rev. Immunol. 8(5), 349-361 (2008). •• Review describing the increasingly recognized role of lipids as signaling molecules. (Pubitemid 351595216)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.5 , pp. 349-361
    • Serhan, C.N.1    Chiang, N.2    Van Dyke, T.E.3
  • 83
    • 77957942833 scopus 로고    scopus 로고
    • Specialized pro-resolving lipid mediators in the inflammatory response: An update
    • Bannenberg G, Serhan CN. Specialized pro-resolving lipid mediators in the inflammatory response: an update. Biochim. Biophys. Acta 1801(12), 1260-1273 (2010).
    • (2010) Biochim. Biophys. Acta , vol.1801 , Issue.12 , pp. 1260-1273
    • Bannenberg, G.1    Serhan, C.N.2
  • 86
    • 77953248904 scopus 로고    scopus 로고
    • Docosahexaenoic acid and synaptic protection in Alzheimer's disease mice
    • Oster T, Pillot T. Docosahexaenoic acid and synaptic protection in Alzheimer's disease mice. Biochim. Biophys. Acta 1801(8), 791-798 (2010).
    • (2010) Biochim. Biophys. Acta , vol.1801 , Issue.8 , pp. 791-798
    • Oster, T.1    Pillot, T.2
  • 87
    • 0028812316 scopus 로고
    • Decreased phospholipase A2 activity in Alzheimer brains
    • Gattaz WF, Maras A, Cairns NJ et al. Decreased phospholipase A2 activity in Alzheimer brains. Biol. Psychiatry 37(1), 13-17 (1995).
    • (1995) Biol. Psychiatry , vol.37 , Issue.1 , pp. 13-17
    • Gattaz, W.F.1    Maras, A.2    Cairns, N.J.3
  • 88
    • 71749104938 scopus 로고    scopus 로고
    • Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity is increased in Alzheimer disease
    • Chalbot S, Zetterberg H, Blennow K et al. Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity is increased in Alzheimer disease. Clin. Chem. 55(12), 2171-2179 (2009).
    • (2009) Clin. Chem , vol.55 , Issue.12 , pp. 2171-2179
    • Chalbot, S.1    Zetterberg, H.2    Blennow, K.3
  • 89
    • 80052477281 scopus 로고    scopus 로고
    • Inhibition of phospholipase A2 in rat brain decreases the levels of total Tau protein
    • Schaeffer EL, De-Paula VJ, da Silva ER et al. Inhibition of phospholipase A2 in rat brain decreases the levels of total Tau protein. J. Neural Transm. 118(9) 1273-1279 (2011).
    • (2011) J. Neural Transm , vol.118 , Issue.9 , pp. 1273-1279
    • Schaeffer, E.L.1    De-Paula, V.J.2    Da Silva, E.R.3
  • 91
    • 2442489033 scopus 로고    scopus 로고
    • Relation of plasma lipids to alzheimer disease and vascular dementia
    • DOI 10.1001/archneur.61.5.705
    • Reitz C, Tang MX, Luchsinger J et al. Relation of plasma lipids to Alzheimer disease and vascular dementia. Arch. Neurol. 61(5), 705-714 (2004). (Pubitemid 38637688)
    • (2004) Archives of Neurology , vol.61 , Issue.5 , pp. 705-714
    • Reitz, C.1    Tang, M.-X.2    Luchsinger, J.3    Mayeux, R.4
  • 93
    • 80053334820 scopus 로고    scopus 로고
    • From brain to food: Analysis of phosphatidylcholins, lyso- phosphatidylcholins and phosphatidylcholin plasmalogens derivates in Alzheimer's disease human post mortem brains and mice model via mass spectrometry
    • Grimm MO, Grösgen S, Riemenschneider M et al. From brain to food: analysis of phosphatidylcholins, lyso-phosphatidylcholins and phosphatidylcholin plasmalogens derivates in Alzheimer's disease human post mortem brains and mice model via mass spectrometry. J. Chromatogr. A 1218, 7713-7722 (2010).
    • (2010) J. Chromatogr. A , vol.1218 , pp. 7713-7722
    • Grimm, M.O.1    Grösgen, S.2    Riemenschneider, M.3
  • 94
    • 84866951189 scopus 로고    scopus 로고
    • Choline-containing phospholipids in microdissected human Alzheimer's disease brain senile plaques versus neuropil
    • Gaudin M, Panchal M, Auzeil N et al. Choline-containing phospholipids in microdissected human Alzheimer's disease brain senile plaques versus neuropil. Bioanalysis 4(17), 2153-2159 (2012).
    • (2012) Bioanalysis , vol.4 , Issue.17 , pp. 2153-2159
    • Gaudin, M.1    Panchal, M.2    Auzeil, N.3
  • 95
    • 0035023152 scopus 로고    scopus 로고
    • Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: Molecular characterization using electrospray ionization mass spectrometry
    • DOI 10.1046/j.1471-4159.2001.00332.x
    • Han X, Holtzman DM, McKeel DW Jr. Plasmalogen deficiency in early Alzheimer's disease subjects and inanimal models: molecular characterization using electrospray ionization mass spectrometry. J. Neurochem.77, 1168-1180 (2001). (Pubitemid 32467071)
    • (2001) Journal of Neurochemistry , vol.77 , Issue.4 , pp. 1168-1180
    • Han, X.1    Holtzman, D.M.2    McKeel Jr., D.W.3
  • 96
    • 75449092205 scopus 로고    scopus 로고
    • Circulating plasmalogen levels and alzheimer disease assessment scale-cognitive scores in alzheimer patients
    • Wood PL, Mankidy R, Ritchie S et al. Circulating plasmalogen levels and Alzheimer Disease Assessment Scale-Cognitive scores in Alzheimer patients. J. Psychiatry Neurosci. 35, 59-62 (2010).
    • (2010) J. Psychiatry Neurosci , vol.35 , pp. 59-62
    • Wood, P.L.1    Mankidy, R.2    Ritchie, S.3
  • 98
    • 79851471469 scopus 로고    scopus 로고
    • Plasmalogen synthesis is regulated by alkyl dihydroxyacetone phosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer's disease
    • Grimm MOW, Kuchenbecker J, Rothhaar TL et al. Plasmalogen synthesis is regulated by alkyl dihydroxyacetone phosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer's disease. J. Neurochem. 116, 916-925 (2011).
    • (2011) J. Neurochem , vol.116 , pp. 916-925
    • Grimm, M.O.W.1    Kuchenbecker, J.2    Rothhaar, T.L.3
  • 99
    • 58149465620 scopus 로고    scopus 로고
    • Reduced membrane lipids in the cortex of Alzheimer's disease transgenic mice
    • Yao JK, Wengenack TM, Curran GL et al. Reduced membrane lipids in the cortex of Alzheimer's disease transgenic mice. Neurochem. Res. 34(1), 102-108 (2009).
    • (2009) Neurochem. Res , vol.34 , Issue.1 , pp. 102-108
    • Yao, J.K.1    Wengenack, T.M.2    Curran, G.L.3
  • 100
    • 39249083317 scopus 로고    scopus 로고
    • Loss of phospholipid asymmetry and elevated apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease
    • Bader Lange ML, Cenini G, Piroddi M et al. Loss of phospholipid asymmetry and elevated apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease. Neurobiol. Dis. 29(3), 456-464 (2008).
    • (2008) Neurobiol. Dis , vol.29 , Issue.3 , pp. 456-464
    • Bader Lange, M.L.1    Cenini, G.2    Piroddi, M.3
  • 102
    • 79955051063 scopus 로고    scopus 로고
    • Linking lipids to Alzheimer's disease: Cholesterol and beyond
    • Di Paolo G, Kim TW. Linking lipids to Alzheimer's disease: cholesterol and beyond. Nat. Rev. 12, 284-296 (2011). •• The complex relationship between Alzheimer's disease and lipid metabolism highlights that cholesterol is not the only lipid partner of great interest in this disease.
    • (2011) Nat. Rev , vol.12 , pp. 284-296
    • Di Paolo, G.1    Kim, T.W.2
  • 104
    • 0028037959 scopus 로고
    • Content and fatty acid composition of cardiolipin in the brain of patients with Alzheimer's disease
    • DOI 10.1016/0197-0186(94)90073-6
    • Guan ZZ, Söderberg M, Sindelar P et al. Content and fatty acid composition of cardiolipin in the brain of patients with Alzheimer's disease. Neurochem. Int. 25(3), 295-300 (1994). (Pubitemid 24282431)
    • (1994) Neurochemistry International , vol.25 , Issue.3 , pp. 295-300
    • Guan, Z.Z.1    Soderberg, M.2    Sindelar, P.3    Edlund, C.4
  • 105
    • 0037490159 scopus 로고    scopus 로고
    • Ceramide stabilizes β-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid β-peptide biogenesis
    • DOI 10.1074/jbc.M300466200
    • Puglielli L, Ellis BC, Saunders AJ et al. Ceramide stabilizes b-site amyloid precursor protein cleaving enzyme 1 and promotes amyloid b-peptide biogenesis. J. Biol. Chem. 278, 19777-19783 (2003). (Pubitemid 36799164)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.22 , pp. 19777-19783
    • Puglielli, L.1    Ellis, B.C.2    Saunders, A.J.3    Kovacs, D.M.4
  • 106
    • 77953268102 scopus 로고    scopus 로고
    • Roles for dysfunctional sphingolipid metabolism inAlzheimer's disease neuropathogenesis
    • Haughey NJ, Bandaru VVR, Bae M et al. Roles for dysfunctional sphingolipid metabolism inAlzheimer's disease neuropathogenesis. Biochim. Biophys. Acta 1801(8), 878-886 (2010).
    • (2010) Biochim. Biophys. Acta , vol.1801 , Issue.8 , pp. 878-886
    • Haughey, N.J.1    Bandaru, V.V.R.2    Bae, M.3
  • 107
    • 78649780371 scopus 로고    scopus 로고
    • Alterations of the sphingolipid pathway in Alzheimer's disease: New biomarkers and treatment targets?
    • Mielke MM, Lyketsos CG. Alterations of the sphingolipid pathway in Alzheimer's disease: new biomarkers and treatment targets? Neuromol. Med. 12, 331-340 (2010).
    • (2010) Neuromol. Med , vol.12 , pp. 331-340
    • Mielke, M.M.1    Lyketsos, C.G.2
  • 108
    • 0036677303 scopus 로고    scopus 로고
    • Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: Potential role in disease pathogenesis
    • Han X, Holtzman DM, McKeel DW Jr, Morris JC et al. Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis. J. Neurochem. 82, 809-818 (2002). • One of the first studies by shotgun lipidomics revealing sphingolipid alterations in Alzheimer's disease.
    • (2002) J. Neurochem , vol.82 , pp. 809-818
    • Han, X.1    Holtzman, D.M.2    McKeel Jr., D.W.3    Morris, J.C.4
  • 109
    • 74149083982 scopus 로고    scopus 로고
    • Deregulation of sphingolipid metabolism in Alzheimer's disease
    • He X, Huang Y, Li B et al. Deregulation of sphingolipid metabolism in Alzheimer's disease. Neurobiol. Aging 31, 398-408 (2010).
    • (2010) Neurobiol. Aging , vol.31 , pp. 398-408
    • He, X.1    Huang, Y.2    Li, B.3
  • 110
    • 33947577504 scopus 로고    scopus 로고
    • Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: A shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease?
    • DOI 10.1007/s11064-007-9297-x
    • Katsel P, Li C, Haroutunian V. Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease. Neurochem. Res. 32, 845-856 (2007). (Pubitemid 46481322)
    • (2007) Neurochemical Research , vol.32 , Issue.4-5 , pp. 845-856
    • Katsel, P.1    Li, C.2    Haroutunian, V.3
  • 112
    • 70449530861 scopus 로고    scopus 로고
    • Serum sphingomyelins and ceramides are early predictors of memory impairment
    • Mielke MM, Bandaru VVR, Haughey NJ et al. Serum sphingomyelins and ceramides are early predictors of memory impairment. Neurobiol. Aging 31, 17-24 (2010).
    • (2010) Neurobiol. Aging , vol.31 , pp. 17-24
    • Mielke, M.M.1    Bandaru, V.V.R.2    Haughey, N.J.3
  • 113
    • 77956381154 scopus 로고    scopus 로고
    • Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss
    • Mielke MM, Haughey NJ, Bandaru VVR et al. Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss. Alzheimers Dement. 6, 378-385 (2010).
    • (2010) Alzheimers Dement , vol.6 , pp. 378-385
    • Mielke, M.M.1    Haughey, N.J.2    Bandaru, V.V.R.3
  • 114
    • 79960114429 scopus 로고    scopus 로고
    • Metabolomics in early Alzheimer's disease: Identification of altered plasma sphingolipidome using shotgun lipidomics
    • Han X, Rozen S, Boyle SH et al. Metabolomics in early Alzheimer's disease: identification of altered plasma sphingolipidome using shotgun lipidomics. PLoS ONE 6(7), e21643v (2011).
    • (2011) PLoS ONE , vol.6 , Issue.7
    • Han, X.1    Rozen, S.2    Boyle, S.H.3
  • 115
    • 84884264199 scopus 로고    scopus 로고
    • Plasma ceramide and glucosylceramide metabolism is altered in sporadic Parkinson's disease and associated with cognitive impairment: A pilot study
    • Mielke MM, Maetzler W, Haughey NJ et al. Plasma ceramide and glucosylceramide metabolism is altered in sporadic Parkinson's disease and associated with cognitive impairment: a pilot study. PLoS ONE. 8(9), e73094 (2013).
    • (2013) PLoS ONE , vol.8 , Issue.9
    • Mielke, M.M.1    Maetzler, W.2    Haughey, N.J.3
  • 116
    • 28644451007 scopus 로고    scopus 로고
    • Regulation of cholesterol and sphingomyelin metabolism by amyloid-b andpresenilin
    • Grimm MOW, Grimm HS, Pätzold AJ et al. Regulation of cholesterol and sphingomyelin metabolism by amyloid-b andpresenilin. Nat. Cell Biol. 7, 1118-1123 (2005).
    • (2005) Nat. Cell Biol , vol.7 , pp. 1118-1123
    • Grimm, M.O.W.1    Grimm, H.S.2    Pätzold, A.J.3
  • 118
    • 61649120841 scopus 로고    scopus 로고
    • ApoE4 disrupts sterol and sphingolipid metabolism in Alzheimer's but not normal brain
    • Bandaru VVR, Troncoso J, Wheeler D et al. ApoE4 disrupts sterol and sphingolipid metabolism in Alzheimer's but not normal brain. Neurobiol. Aging 30, 591-599 (2009).
    • (2009) Neurobiol. Aging , vol.30 , pp. 591-599
    • Bandaru, V.V.R.1    Troncoso, J.2    Wheeler, D.3
  • 120
    • 0037424260 scopus 로고    scopus 로고
    • Novel role for apolipoprotein E in the central nervous system: Modulation of sulfatide content
    • DOI 10.1074/jbc.M212340200
    • Han X, Cheng H, Fryer JD et al. Novel role for apolipoprotein E in the central nervous system. modulation of sulfatide content. J. Biol. Chem. 278, 8043-8051 (2003). (Pubitemid 36800543)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.10 , pp. 8043-8051
    • Han, X.1    Cheng, H.2    Fryer, J.D.3    Fagan, A.M.4    Holtzman, D.M.5
  • 121
    • 0038479920 scopus 로고    scopus 로고
    • Cerebrospinal fluid sulfatide is decreased in subjects with incipient dementia
    • Han X, Fagan AM, Cheng H et al. Cerebrospinal fluid sulfatide is decreased in subjects with incipient dementia. Ann. Neurol. 54, 115-118 (2003).
    • (2003) Ann. Neurol , vol.54 , pp. 115-118
    • Han, X.1    Fagan, A.M.2    Cheng, H.3
  • 123
    • 55749095544 scopus 로고    scopus 로고
    • Age-dependent high-density clustering of GM1 ganglioside at presynaptic neuritic terminals promotes amyloid b-protein fibrillogenesis
    • Yamamoto N, Matsubara T, Sato T et al. Age-dependent high-density clustering of GM1 ganglioside at presynaptic neuritic terminals promotes amyloid b-protein fibrillogenesis. Biochim. Biophys. Acta 1778, 2117-2126 (2008).
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 2117-2126
    • Yamamoto, N.1    Matsubara, T.2    Sato, T.3
  • 124
    • 77953235479 scopus 로고    scopus 로고
    • Ab polymerization through interaction with membrane gangliosides
    • Matsuzaki K, Kato K, Yanagisawa K. Ab polymerization through interaction with membrane gangliosides. Biochim. Biophys. Acta 868-877 (2010) (1801).
    • (2010) Biochim. Biophys. Acta , vol.868-877 , pp. 1801
    • Matsuzaki, K.1    Kato, K.2    Yanagisawa, K.3
  • 126
    • 35648990044 scopus 로고    scopus 로고
    • Role of lipid rafts in the processing of the pathogenic prion and Alzheimer's amyloid-β proteins
    • DOI 10.1016/j.semcdb.2007.07.008, PII S1084952107000985, Membrane Lipid Microdomains: Roles in Signalling and Disease and 3D Chromatin
    • Taylor DR, Hooper NM. Role of lipid rafts in the processing of the pathogenic prion and Alzheimer's amyloid-b proteins. Sem. Cell. Devel. Biol. 18, 638-648 (2007). (Pubitemid 350030896)
    • (2007) Seminars in Cell and Developmental Biology , vol.18 , Issue.5 , pp. 638-648
    • Taylor, D.R.1    Hooper, N.M.2
  • 130
    • 77950615783 scopus 로고    scopus 로고
    • Enrichment of cholesterol in microdissected Alzheimer's disease senile plaques as assessed by mass spectrometry
    • Panchal M, Loeper J, Cossec JC et al. Enrichment of cholesterol in microdissected Alzheimer's disease senile plaques as assessed by mass spectrometry. J. Lipid Res. 51(3), 598-605 (2010). • First study unambiguously evaluating the lipid content of the senile plaque.
    • (2010) J. Lipid Res , vol.51 , Issue.3 , pp. 598-605
    • Panchal, M.1    Loeper, J.2    Cossec, J.C.3
  • 131
    • 38049056730 scopus 로고    scopus 로고
    • Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice
    • Martins IC, Kuperstein I, Wilkinson H et al. Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice. EMBO J. 27, 224-233 (2008).
    • (2008) EMBO J. , vol.27 , pp. 224-233
    • Martins, I.C.1    Kuperstein, I.2    Wilkinson, H.3
  • 132
    • 77649259094 scopus 로고    scopus 로고
    • ACAT1 gene ablation increases 24(S) hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD
    • Bryleva EY, Rogers MA, Chang CCY et al. ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD. Proc. Natl Acad. Sci. USA 107, 3081-3086 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 3081-3086
    • Bryleva, E.Y.1    Rogers, M.A.2    Chang, C.C.Y.3
  • 133
    • 84872382364 scopus 로고    scopus 로고
    • Alzheimer's disease, cholesterol, and statins: The junctions of important metabolic pathways
    • Silva T, Teixeira J, Remião F, Borges F. Alzheimer's disease, cholesterol, and statins: the junctions of important metabolic pathways. Angew. Chem. Int. Ed. Engl. 52(4), 1110-1121 (2013).
    • (2013) Angew. Chem. Int. Ed. Engl , vol.52 , Issue.4 , pp. 1110-1121
    • Silva, T.1    Teixeira, J.2    Remião, F.3    Borges, F.4
  • 134
    • 84863510126 scopus 로고    scopus 로고
    • The link between altered cholesterol metabolism and Alzheimer's disease
    • Gamba P, Testa G, Sottero B et al. The link between altered cholesterol metabolism and Alzheimer's disease. Ann. NY Acad. Sci. 1259, 54-64 (2012).
    • (2012) Ann. NY Acad. Sci , vol.1259 , pp. 54-64
    • Gamba, P.1    Testa, G.2    Sottero, B.3
  • 135
    • 0036660259 scopus 로고    scopus 로고
    • Use of vitamin C and E in the treatment of Alzheimer's disease
    • DOI 10.1002/ddr.10107
    • Arlt S, Müller-Thomsen T, Beisiegel U. Use of vitamin C and E in the treatment of Alzheimer's disease. Drug Dev. Res. 56, 452-457 (2002). (Pubitemid 35168322)
    • (2002) Drug Development Research , vol.56 , Issue.3 , pp. 452-457
    • Arlt, S.1    Muller-Thomsen, T.2    Beisiegel, U.3
  • 136
    • 84872468949 scopus 로고    scopus 로고
    • Low serum vitamin D concentrations in Alzheimer's disease: A systematic review and meta-analysis
    • Annweiler C, Llewellyn DJ, Beauchet O. Low serum vitamin D concentrations in Alzheimer's disease: a systematic review and meta-analysis. J. Alzheimer Dis. 33(3), 659-674 (2013).
    • (2013) J. Alzheimer Dis , vol.33 , Issue.3 , pp. 659-674
    • Annweiler, C.1    Llewellyn, D.J.2    Beauchet, O.3
  • 138
    • 84859004158 scopus 로고    scopus 로고
    • Vitamin A and Alzheimer's disease
    • Ono K, Yamada M. Vitamin A and Alzheimer's disease. Geriatr. Gerontol. Int. 12(2), 180-188 (2012).
    • (2012) Geriatr. Gerontol. Int , vol.12 , Issue.2 , pp. 180-188
    • Ono, K.1    Yamada, M.2
  • 139
    • 78650420189 scopus 로고    scopus 로고
    • Identifying and validating biomarkers for Alzheimer's disease
    • Humpel C. Identifying and validating biomarkers for Alzheimer's disease. Trends Biotechnol. 29(1) 26-32 (2001).
    • (2001) Trends Biotechnol , vol.29 , Issue.1 , pp. 26-32
    • Humpel, C.1
  • 140
    • 84881287638 scopus 로고    scopus 로고
    • Imaging markers for Alzheimer disease: Which vs how
    • Frisoni GB, Bocchetta M, Chételat G et al. Imaging markers for Alzheimer disease: which vs how. Neurology 81(5), 487-500 (2013).
    • (2013) Neurology , vol.81 , Issue.5 , pp. 487-500
    • Frisoni, G.B.1    Bocchetta, M.2    Chételat, G.3
  • 141
    • 0036903299 scopus 로고    scopus 로고
    • Molecular imaging of amyloid β peptides in mouse brain sections using mass spectrometry
    • DOI 10.1016/S0003-2697(02)00386-X, PII S000326970200386X
    • Stoeckli M, Staab D, Staufenbiel M et al. Molecular imaging of amyloid beta peptides in mouse brain sections using mass spectrometry. Anal. Biochem. 311(1), 33-39 (2002). (Pubitemid 35463486)
    • (2002) Analytical Biochemistry , vol.311 , Issue.1 , pp. 33-39
    • Stoeckli, M.1    Staab, D.2    Staufenbiel, M.3    Wiederhold, K.-H.4    Signor, L.5
  • 142
    • 27644569773 scopus 로고    scopus 로고
    • Imaging and spatial distribution of β-amyloid peptide and metal ions in Alzheimer's plaques by laser ablation-inductively coupled plasma-mass spectrometry
    • DOI 10.1016/j.ab.2005.08.024, PII S0003269705006044
    • Hutchinson RW, Cox AG, McLeod CW et al. Imaging and spatial distribution of beta-amyloid peptide and metal ions in Alzheimer's plaques by laser ablation-inductively coupled plasma mass spectrometry. Anal. Biochem. 346(2), 225-233 (2005). (Pubitemid 41550254)
    • (2005) Analytical Biochemistry , vol.346 , Issue.2 , pp. 225-233
    • Hutchinson, R.W.1    Cox, A.G.2    McLeod, C.W.3    Marshall, P.S.4    Harper, A.5    Dawson, E.L.6    Howlett, D.R.7
  • 143
    • 80052488002 scopus 로고    scopus 로고
    • Hydroxylated and non-hydroxylated sulfatide are distinctly distributed in the human cerebral cortex
    • Yuki D, Sugiura Y, Zaima N et al. Hydroxylated and non-hydroxylated sulfatide are distinctly distributed in the human cerebral cortex. Neuroscience 193, 44-53 (2011).
    • (2011) Neuroscience , vol.193 , pp. 44-53
    • Yuki, D.1    Sugiura, Y.2    Zaima, N.3
  • 144
    • 84872340627 scopus 로고    scopus 로고
    • Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients
    • Lazar AN, Bich C, Panchal M et al. Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients. Acta Neuropathol. 125(1), 133-144 (2013).
    • (2013) Acta Neuropathol , vol.125 , Issue.1 , pp. 133-144
    • Lazar, A.N.1    Bich, C.2    Panchal, M.3
  • 146
    • 77952035934 scopus 로고    scopus 로고
    • Comprehensive LC-MSE lipidomic analysis using a shotgun approach and its application to biomarker detection and identification in osteoarthritis patients
    • Castro-Perez JM, Kamphorst J, DeGroot J et al. Comprehensive LC-MSE lipidomic analysis using a shotgun approach and its application to biomarker detection and identification in osteoarthritis patients. J. Proteome Res. 9(5), 2377-2389 (2010).
    • (2010) J. Proteome Res , vol.9 , Issue.5 , pp. 2377-2389
    • Castro-Perez, J.M.1    Kamphorst, J.2    Degroot, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.