Metabolomics in early Alzheimer's disease: Identification of altered plasma sphingolipidome using shotgun lipidomics

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Han, Xianlin ^a   Rozen, Steve ^b   Boyle, Stephen H ^c   Hellegers, Caroline ^c   Cheng, Hua ^a   Burke, James R ^c   Welsh Bohmer, Kathleen A ^c   Doraiswamy, P Murali ^c   Kaddurah Daouk, Rima ^c  

^a BURNHAM INSTITUTE   (United States)

^b DUKE NUS MEDICAL SCHOOL   (Singapore)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4; BIOLOGICAL MARKER; CARBON; CERAMIDE; LYSOPHOSPHOLIPID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLINOSITOL; SPHINGOLIPID; SPHINGOMYELIN; TRIACYLGLYCEROL; APOLIPOPROTEIN E;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GENETIC VARIABILITY; GENOTYPE; HUMAN; LIPID BLOOD LEVEL; LIPIDOMICS; MALE; METABOLOMICS; NEUROPATHOLOGY; REPRODUCIBILITY; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY; BLOOD; CASE CONTROL STUDY; GENETICS; MASS SPECTROMETRY; METHODOLOGY; MIDDLE AGED; PROSPECTIVE STUDY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEINS E; CASE-CONTROL STUDIES; FEMALE; GENOTYPE; HUMANS; MALE; MASS SPECTROMETRY; METABOLOMICS; MIDDLE AGED; PROSPECTIVE STUDIES; SPHINGOLIPIDS;

EID: 79960114429     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021643     Document Type: Article

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