Imaging and spatial distribution of β-amyloid peptide and metal ions in Alzheimer's plaques by laser ablation-inductively coupled plasma-mass spectrometry

Analytical Biochemistry

Volumn 346, Issue 2, 2005, Pages 225-233

  Hutchinson, Robert W ^a   Cox, Alan G ^a   McLeod, Cameron W ^a   Marshall, Peter S ^b   Harper, Alex ^b   Dawson, Emma L ^b   Howlett, David R ^b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Alzheimer's disease; Antibody labeling; beta Amyloid; Eu; Imaging; Inductively coupled plasma mass spectrometry; Laser ablation; Laser capture microdissection; Ni; Trace elements

Indexed keywords

ABLATION; ANTIBODIES; EUROPIUM; GLYCOPROTEINS; IMAGING TECHNIQUES; INDUCTIVELY COUPLED PLASMA; INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY; MASS SPECTROMETERS; METAL IONS; METALS; MICRODISSECTION; NEURODEGENERATIVE DISEASES; NICKEL; TRACE ELEMENTS;

ALZHEIMER'S DISEASE; ANTIBODY LABELING; BETA AMYLOIDS; LASER ABLATION INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRIES (LA ICP MS); LASER ABLATION INDUCTIVELY-COUPLED PLASMA MASS SPECTROMETRIES; LASER CAPTURE MICRODISSECTION; TRACE ELEMENT DISTRIBUTION; TWO-DIMENSIONAL IMAGING;

LASER ABLATION;

AMYLOID BETA PROTEIN[25-35]; ANTIBODY; ELEMENT; EUROPIUM; METAL ION; NICKEL; PROTEIN; TRACE ELEMENT;

ALZHEIMER DISEASE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; EXPERIMENTAL MODEL; IMMUNOHISTOCHEMISTRY; LASER CAPTURE MICRODISSECTION; MASS SPECTROMETRY; METHODOLOGY; MICROANALYSIS; MOLECULAR PROBE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; SENILE PLAQUE; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS;

EID: 27644569773     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2005.08.024     Document Type: Article

References (24)

1. G. Perry, L.M. Sayre, C.S. Atwood, R.J. Castellani, A.D. Cash, C.A. Rottkamp, and M.A. Smith The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications CNS Drugs 16 2002 339 352
2. 2+ from brain tissue during activity Nature 308 1984 734 736
3. M.B. Youdim, and P. Riederer The role of iron in senescence of dopaminergic neurons in Parkinson's disease J. Neural. Transm. 40 Suppl. 1993 57 67
4. D. Strausak, J.F.B. Mercer, H.H. Dieter, W. Stremmel, and G. Multhaup Copper in disorders with neurological symptoms: Alzheimer's, Menkes, and Wilson diseases Brain Res. Bull. 55 2001 175 185
5. D. Beauchemin, and R. Kisilevsky A method based on ICP-MS for the analysis of Alzheimer's amyloid plaques Anal. Chem. 70 1998 1026 1029
6. J.G. Beeson, E.R. Shelton, H.W. Chan, and F.H. Gage Differential distribution of amyloid protein precursor immunoreactivity in the rat brain studied by using five different antibodies J. Comp. Neurol. 342 1994 78 96
7. M. Stoeckli, D. Staab, M. Staufenbiel, K.-H. Wiederhold, and L. Signor Molecular imaging of amyloid β peptides in mouse brain sections using mass spectrometry Anal. Biochem. 311 2002 33 39
8. P. Rüfenacht, A. Güntert, B. Bohrmann, A. Ducret, and H. Döbeli Quantification of the Ab peptide in Alzheimer's plaques by laser dissection microscopy combined with mass spectrometry J. Mass Spectrom. 40 2005 193 201
9. P. Schramel, and I. Wendler Capabilities of double focusing magnetic sector-ICP-MS for the determination of trace elements in body fluids (blood, blood serum, urine) at the example of control materials Fresenius J. Anal. Chem. 361 1998 487 491
10. T.W. May, R.H. Wiedmeyer, L.D. Brown, and S.W. Casteel A lead isotope distribution study in swine tissue using ICP-MS Atom. Spectrosc. 20 1999 199 211
11. Laser ablation-ICP-MS in the Earth sciences, Paul Sylvester (Ed). Mineralogical Association of Canada. Short Course Series vol. 29.
12. R. Ma, C.W. McLeod, K. Tomlinson, and R.K. Poole Speciation of protein-bound trace elements by gel electrophoresis and atomic spectrometry Electrophoresis 25 2004 2469 2477
13. P.S. Marshall, O. Heudi, S. Bains, H. Freeman, F. Abou-Shakra, and K. Reardon The determination of protein phosphorylation on electrophoresis gel blots by laser ablation inductively coupled plasma-mass spectrometry Analyst 127 2002 459 461
14. T.W.M. Fan, E. Pruszkowski, and S. Shuttleworth Speciation of selenoproteins in Se-contaminated wildlife by gel electrophoresis and laser ablation-ICP-MS J. Anal. Atom. Spectrom. 17 2002 1621 1623
15. S. Wang, R. Brown, and D.J. Gray Application of laser ablation-ICP-MS to the spatially resolved micro-analysis of biological tissue Appl. Spectrosc. 48 1994 1321 1325
16. A. Kindness, C.N. Sekaran, and J. Feldmann Two-dimensional mapping of copper and zinc in liver sections by laser ablation-inductively coupled plasma-mass spectrometry Clin. Chem. 49 2003 1916 1923
17. J.S. Becker, S.F. Boulyga, J.S. Becker, C. Pickhardt, E. Damoc, and M. Przybylski Structural identification and quantification of protein phosphorylations after gel electrophoretic separation using Fourier transform ion cyclotron resonance mass spectrometry and laser ablation-inductively coupled plasma-mass spectrometry Int. J. Mass Spectrom. 228 2003 985 997
18. J.S. Becker, M.V. Zoriy, C. Pickhardt, N. Palomero-Gallagher, and K. Zilles Imaging of copper, zinc, and other elements in thin section of human brain samples (hippocampus) by laser ablation-inductively couple plasma-mass spectrometry Anal. Chem. 77 2005 3208 3216
19. C. Zhang, F.B. Wu, Y.Y. Zhang, X. Wang, and X.R. Zhang A novel combination of immunoreaction and ICP-MS as a hyphenated technique for the determination of thyroid-stimulating hormone (TSH) in human serum J. Anal. Atom. Spectrom. 16 2001 1393 1396
20. S.C. Zhang, C. Zhang, Z. Xing, and X.R. Zhang Simultaneous determination of -fetoprotein and free β-human chorionic gonadotropin by element-tagged immunoassay with detection by inductively coupled plasma-mass spectrometry Clin. Chem. 50 2004 1214 1221
21. Z.A. Quinn, V.I. Baranov, D.R. Bandura, and S.D. Tanner Simultaneous determination of proteins using an element-tagged immunoassay coupled with ICP-MS detection J. Anal. Atom. Spectrom. 17 2002 892 896
22. V.I. Baranov, Z.A. Quinn, D.R. Bandura, and S.D. Tanner A sensitive and quantitative element-tagged immunoassay with ICP-MS detection Anal. Chem. 74 2002 1629 1636
23. R.W. Hutchinson, R. Ma, C.W. McLeod, A. Milford-Ward, and D. Lee Immunoassay with FI-ICP-MS detection-measurement of free and total prostate specific antigen in human serum Can. J. Anal. Sci. Spectrosc. 49 2004 429 435
24. D.R. Howlett, J.C. Richardson, A. Austin, A.A. Parsons, S.T. Bate, D.C. Davies, and M.I. Gonzalez Cognitive correlates of Aβ deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes Brain Res. 1017 2004 130 136