-
1
-
-
0033977413
-
Time-course of oxidation of lipids in human cerebrospinal fluid in vitro
-
Arlt S, Finckh B, Beisiegel U, Kontush A. 2000. Time-course of oxidation of lipids in human cerebrospinal fluid in vitro. Free Radic Res 32:103-114.
-
(2000)
Free Radic Res
, vol.32
, pp. 103-114
-
-
Arlt, S.1
Finckh, B.2
Beisiegel, U.3
Kontush, A.4
-
2
-
-
0035985698
-
Lipid peroxidation in neurodegeneration: New insights into Alzheimer's disease
-
Arlt S, Beisiegel U, Kontush A. 2002. Lipid peroxidation in neurodegeneration: new insights into Alzheimer's disease. Curr Opin Lipidol 13:289-294.
-
(2002)
Curr Opin Lipidol
, vol.13
, pp. 289-294
-
-
Arlt, S.1
Beisiegel, U.2
Kontush, A.3
-
3
-
-
0034186642
-
Vitamin E supplementation increases the resistance of both LDL and HDL to oxidation and increases cholesteryl ester transfer activity
-
Arrol S, Mackness MI, Durrington PN. 2000. Vitamin E supplementation increases the resistance of both LDL and HDL to oxidation and increases cholesteryl ester transfer activity. Atherosclerosis 150:129-134.
-
(2000)
Atherosclerosis
, vol.150
, pp. 129-134
-
-
Arrol, S.1
Mackness, M.I.2
Durrington, P.N.3
-
4
-
-
0033374599
-
Cerebrospinal fluid lipoproteins are more vulnerable to oxidation in Alzheimer's disease and are neurotoxic when oxidized ex vivo
-
Bassett CN, Neely MD, Sidell KB, Markesbery WB, Swift LL, Montine TJ. 1999. Cerebrospinal fluid lipoproteins are more vulnerable to oxidation in Alzheimer's disease and are neurotoxic when oxidized ex vivo. Lipids 34:1273-1280.
-
(1999)
Lipids
, vol.34
, pp. 1273-1280
-
-
Bassett, C.N.1
Neely, M.D.2
Sidell, K.B.3
Markesbery, W.B.4
Swift, L.L.5
Montine, T.J.6
-
6
-
-
0028917535
-
The health effects of vitamin C supplementation: A review
-
Bendich A, Langseth L. 1995. The health effects of vitamin C supplementation: a review. J Am Coll Nutr 14:124-136.
-
(1995)
J Am Coll Nutr
, vol.14
, pp. 124-136
-
-
Bendich, A.1
Langseth, L.2
-
7
-
-
0034035616
-
Metals and neuroscience
-
Bush AI. 2000. Metals and neuroscience. Curr Opin Chem Biol 4:184-191.
-
(2000)
Curr Opin Chem Biol
, vol.4
, pp. 184-191
-
-
Bush, A.I.1
-
8
-
-
0342547342
-
Graded dietary levels of RRR-gamma-tocopherol induce a marked increase in the concentrations of alpha- and gamma-tocopherol in nervous tissues, heart, liver, and muscle of vitamin-E-deficient rats
-
Clement M, Bourre JM. 1997. Graded dietary levels of RRR-gamma-tocopherol induce a marked increase in the concentrations of alpha- and gamma-tocopherol in nervous tissues, heart, liver, and muscle of vitamin-E-deficient rats. Biochim Biophys Acta 1334:173-181.
-
(1997)
Biochim Biophys Acta
, vol.1334
, pp. 173-181
-
-
Clement, M.1
Bourre, J.M.2
-
9
-
-
0026636491
-
A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson's disease
-
Fahn S. 1992. A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson's disease. Ann Neurol 32 (suppl):S128-S132.
-
(1992)
Ann Neurol
, vol.32
, Issue.SUPPL.
-
-
Fahn, S.1
-
10
-
-
0001218860
-
Ascorbate is an outstanding antioxidant in human blood plasma
-
Frei B, England L, Ames BN. 1989. Ascorbate is an outstanding antioxidant in human blood plasma. Proc Natl Acad Sci USA 86:6377-6381.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 6377-6381
-
-
Frei, B.1
England, L.2
Ames, B.N.3
-
11
-
-
0033958696
-
Vitamin E and Alzheimer disease: The basis for additional clinical trials
-
Grundman M. 2000. Vitamin E and Alzheimer disease: the basis for additional clinical trials. Am J Clin Nutr 71:630S-636S.
-
(2000)
Am J Clin Nutr
, vol.71
-
-
Grundman, M.1
-
12
-
-
0032904130
-
Microglia and Alzheimer's disease
-
Kalaria RN. 1999. Microglia and Alzheimer's disease. Curr Opin Hematol 6:15-24.
-
(1999)
Curr Opin Hematol
, vol.6
, pp. 15-24
-
-
Kalaria, R.N.1
-
13
-
-
0034904940
-
Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta
-
Kolsch H, Ludwig M, Lutjohann D, Rao ML. 2001. Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta. J Neural Transm 108:475-488.
-
(2001)
J Neural Transm
, vol.108
, pp. 475-488
-
-
Kolsch, H.1
Ludwig, M.2
Lutjohann, D.3
Rao, M.L.4
-
14
-
-
0003193332
-
Measurement of oxidizability of blood plasma
-
Kontush A, Beisiegel U. 1999. Measurement of oxidizability of blood plasma. Methods Enzymol 49:29935-29949.
-
(1999)
Methods Enzymol
, vol.49
, pp. 29935-29949
-
-
Kontush, A.1
Beisiegel, U.2
-
15
-
-
0035425880
-
Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease
-
Kontush A, Mann U, Arlt S, Ujeyl A, Luhrs C, Muller-Thomsen T, Beisiegel U. 2001. Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease. Free Radic Biol Med 31:345-354.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 345-354
-
-
Kontush, A.1
Mann, U.2
Arlt, S.3
Ujeyl, A.4
Luhrs, C.5
Muller-Thomsen, T.6
Beisiegel, U.7
-
16
-
-
0029992521
-
The effect of ascorbate and ubiquinone supplementation on plasma and CSF total antioxidant capacity
-
Lonnrot K, Metsa-Ketela T, Molnar G, Ahonen JP, Latvala M, Peltola J, Pietila T, Alho H. 1996. The effect of ascorbate and ubiquinone supplementation on plasma and CSF total antioxidant capacity. Free Radic Biol Med 21:211-217.
-
(1996)
Free Radic Biol Med
, vol.21
, pp. 211-217
-
-
Lonnrot, K.1
Metsa-Ketela, T.2
Molnar, G.3
Ahonen, J.P.4
Latvala, M.5
Peltola, J.6
Pietila, T.7
Alho, H.8
-
17
-
-
0029073455
-
Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease
-
Lovell MA, Ehmann WD, Butler SM, Markesbery WR. 1995. Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease. Neurology 45:1594-1601.
-
(1995)
Neurology
, vol.45
, pp. 1594-1601
-
-
Lovell, M.A.1
Ehmann, W.D.2
Butler, S.M.3
Markesbery, W.R.4
-
18
-
-
0035112495
-
Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures
-
Lovell MA, Xie C, Markesbery WR. 2001. Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiol Aging 22:187-194.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 187-194
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
19
-
-
0030915855
-
Oxidative stress hypothesis in Alzheimer's disease
-
Markesbery WR. 1997. Oxidative stress hypothesis in Alzheimer's disease. Free Radic Biol Med 23:134-147.
-
(1997)
Free Radic Biol Med
, vol.23
, pp. 134-147
-
-
Markesbery, W.R.1
-
20
-
-
0031980065
-
Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease
-
Markesbery WR, Lovell MA. 1998. Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease. Neurobiol Aging 19:33-36.
-
(1998)
Neurobiol Aging
, vol.19
, pp. 33-36
-
-
Markesbery, W.R.1
Lovell, M.A.2
-
21
-
-
0034834620
-
Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde
-
McGrath LT, McGleenon BM, Brennan S, McColl D, McILroy S, Passmore AP. 2001. Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde. QJM 94:485-490.
-
(2001)
QJM
, vol.94
, pp. 485-490
-
-
McGrath, L.T.1
McGleenon, B.M.2
Brennan, S.3
McColl, D.4
McILroy, S.5
Passmore, A.P.6
-
22
-
-
0023722150
-
Effect of dietary vitamin E and selenium on susceptibility of brain regions to lipid peroxidation
-
Meydani M, Macauley JB, Blumberg JB. 1988. Effect of dietary vitamin E and selenium on susceptibility of brain regions to lipid peroxidation. Lipids 23:405-409.
-
(1988)
Lipids
, vol.23
, pp. 405-409
-
-
Meydani, M.1
Macauley, J.B.2
Blumberg, J.B.3
-
23
-
-
0031845469
-
Assessment of the safety of supplementation with different amounts of vitamin E in healthy older adults
-
Meydani SN, Meydani M, Blumberg JB, Leka LS, Pedrosa M, Diamond R, Schaefer EJ. 1998. Assessment of the safety of supplementation with different amounts of vitamin E in healthy older adults. Am J Clin Nutr 68:311-318.
-
(1998)
Am J Clin Nutr
, vol.68
, pp. 311-318
-
-
Meydani, S.N.1
Meydani, M.2
Blumberg, J.B.3
Leka, L.S.4
Pedrosa, M.5
Diamond, R.6
Schaefer, E.J.7
-
24
-
-
0031028437
-
Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of APOE4
-
Montine KS, Olson SJ, Amarnath V, Whetsell WO, Jr., Graham DG, Montine TJ. 1997. Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of APOE4. Am J Pathol 150:437-443.
-
(1997)
Am J Pathol
, vol.150
, pp. 437-443
-
-
Montine, K.S.1
Olson, S.J.2
Amarnath, V.3
Whetsell W.O., Jr.4
Graham, D.G.5
Montine, T.J.6
-
25
-
-
0032588611
-
Increased CSF F2-isoprostane concentration in probable AD
-
Montine TJ, Beal MF, Cudkowicz ME, O'Donnell H, Margolin RA, McFarland L, Bachrach AF, Zackert WE, Roberts LJ, Morrow JD. 1999. Increased CSF F2-isoprostane concentration in probable AD. Neurology 52:562-565.
-
(1999)
Neurology
, vol.52
, pp. 562-565
-
-
Montine, T.J.1
Beal, M.F.2
Cudkowicz, M.E.3
O'Donnell, H.4
Margolin, R.A.5
McFarland, L.6
Bachrach, A.F.7
Zackert, W.E.8
Roberts, L.J.9
Morrow, J.D.10
-
26
-
-
0033006380
-
The lipid peroxidation product 4-hydroxynonenal inhibits neurite outgrowth, disrupts neuronal microtubules, and modifies cellular tubulin
-
Neely MD, Sidell KR, Graham DG, Montine TJ. 1999. The lipid peroxidation product 4-hydroxynonenal inhibits neurite outgrowth, disrupts neuronal microtubules, and modifies cellular tubulin. J Neurochem 72:2323-2333.
-
(1999)
J Neurochem
, vol.72
, pp. 2323-2333
-
-
Neely, M.D.1
Sidell, K.R.2
Graham, D.G.3
Montine, T.J.4
-
27
-
-
0034900835
-
The role of vitamin E in atherogenesis: Linking the chemical, biological and clinical aspects of the disease
-
Neuzil J, Weber C, Kontush A. 2001. The role of vitamin E in atherogenesis: linking the chemical, biological and clinical aspects of the disease. Atherosclerosis 157:257-283.
-
(2001)
Atherosclerosis
, vol.157
, pp. 257-283
-
-
Neuzil, J.1
Weber, C.2
Kontush, A.3
-
28
-
-
0027530638
-
Effects of tocopherol and deprenyl on the progression of disibility in early Parldnson's disease
-
Parkinson Study Group. 1993. Effects of tocopherol and deprenyl on the progression of disibility in early Parldnson's disease. N Engl J Med 328:176-183.
-
(1993)
N Engl J Med
, vol.328
, pp. 176-183
-
-
-
29
-
-
0035857493
-
Acrolein inhibits respiration in isolated brain mitochondria
-
Picklo MJ, Montine TJ. 2001. Acrolein inhibits respiration in isolated brain mitochondria. Biochim Biophys Acta 1535:145-152.
-
(2001)
Biochim Biophys Acta
, vol.1535
, pp. 145-152
-
-
Picklo, M.J.1
Montine, T.J.2
-
30
-
-
0032238783
-
Increased F2-isoprostanes in Alzheimer's disease: Evidence for enhanced lipid peroxidation in vivo
-
Pratico D, Lee VMY, Trojanowski JQ, Rokach J, FitzGerald GA. 1998. Increased F2-isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidation in vivo. FASEB J 12:1777-1783.
-
(1998)
FASEB J
, vol.12
, pp. 1777-1783
-
-
Pratico, D.1
Lee, V.M.Y.2
Trojanowski, J.Q.3
Rokach, J.4
FitzGerald, G.A.5
-
31
-
-
0027279397
-
Ascorbate concentration in human cerebrospinal fluid (CSF) and serum. Intrathecal accumulation and CSF flow rate
-
Reiber H, Ruff M, Uhr M. 1993. Ascorbate concentration in human cerebrospinal fluid (CSF) and serum. Intrathecal accumulation and CSF flow rate. Clin Chim Acta 217:163-173.
-
(1993)
Clin Chim Acta
, vol.217
, pp. 163-173
-
-
Reiber, H.1
Ruff, M.2
Uhr, M.3
-
32
-
-
0034194081
-
Ascorbate regulation and its neuroprotective role in the brain
-
Rice ME. 2000. Ascorbate regulation and its neuroprotective role in the brain. Trends Neurosci 23:209-216.
-
(2000)
Trends Neurosci
, vol.23
, pp. 209-216
-
-
Rice, M.E.1
-
33
-
-
0027365482
-
Dietary supplementation with vitamins C and E inhibits in vitro oxidation of lipoproteins
-
Rifici VA, Khachadurian AK. 1993. Dietary supplementation with vitamins C and E inhibits in vitro oxidation of lipoproteins. J Am Coll Nutr 12:631-637.
-
(1993)
J Am Coll Nutr
, vol.12
, pp. 631-637
-
-
Rifici, V.A.1
Khachadurian, A.K.2
-
34
-
-
0034738365
-
Will antioxidants fulfill their expectations for the treatment of Alzheimer disease?
-
Rottkamp CA, Nunomura A, Hirai K, Sayre LM, Perry G, Smith MA. 2000. Will antioxidants fulfill their expectations for the treatment of Alzheimer disease? Mech Aging Dev 116:169-179.
-
(2000)
Mech Aging Dev
, vol.116
, pp. 169-179
-
-
Rottkamp, C.A.1
Nunomura, A.2
Hirai, K.3
Sayre, L.M.4
Perry, G.5
Smith, M.A.6
-
35
-
-
0030967165
-
A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study
-
Sano M, Ernesto C, Thomas RG, Klauber MR, Schafer K, Grundman M, Woodbury P, Growdon J, Cotman CW, Pfeiffer E, Schneider LS, Thal LJ. 1997. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study. N Eugl J Med 336:1216-1222.
-
(1997)
N Eugl J Med
, vol.336
, pp. 1216-1222
-
-
Sano, M.1
Ernesto, C.2
Thomas, R.G.3
Klauber, M.R.4
Schafer, K.5
Grundman, M.6
Woodbury, P.7
Growdon, J.8
Cotman, C.W.9
Pfeiffer, E.10
Schneider, L.S.11
Thal, L.J.12
-
36
-
-
0035003439
-
Chemistry and biochemistry of oxidative stress in neurodegenerative disease
-
Sayre LM, Smith MA, Perry G. 2001. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr Med Chem 8:721-738.
-
(2001)
Curr Med Chem
, vol.8
, pp. 721-738
-
-
Sayre, L.M.1
Smith, M.A.2
Perry, G.3
-
37
-
-
0030989545
-
4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
-
Sayre LM, Zelasko DA, Harris PL, Perry G, Salomon RG, Smith MA. 1997. 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J Neurochem 68:2092-2097.
-
(1997)
J Neurochem
, vol.68
, pp. 2092-2097
-
-
Sayre, L.M.1
Zelasko, D.A.2
Harris, P.L.3
Perry, G.4
Salomon, R.G.5
Smith, M.A.6
-
38
-
-
0033951991
-
Increased lipoprotein oxidation in Alzheimer's disease
-
Schippling S, Kontush A, Arlt S, Buhmann C, Sturenburg HJ, Mann U, Muller-Thomsen T, Beisiegel U. 2000. Increased lipoprotein oxidation in Alzheimer's disease. Free Radic Biol Med 28:351-360.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 351-360
-
-
Schippling, S.1
Kontush, A.2
Arlt, S.3
Buhmann, C.4
Sturenburg, H.J.5
Mann, U.6
Muller-Thomsen, T.7
Beisiegel, U.8
-
39
-
-
0025790342
-
Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease
-
Smith CD, Carney JM, Starke-Reed PE, Oliver CN, Stadtman ER, Floyd RA, Markesbery WR. 1991. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proc Natl Acad Sci USA 88:10540-10543.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 10540-10543
-
-
Smith, C.D.1
Carney, J.M.2
Starke-Reed, P.E.3
Oliver, C.N.4
Stadtman, E.R.5
Floyd, R.A.6
Markesbery, W.R.7
-
40
-
-
0029982815
-
Oxidative damage in Alzheimer's
-
Smith MA, Perry G, Richey PL, Sayre LM, Anderson VE, Beal MF, Kowall N. 1996. Oxidative damage in Alzheimer's. Nature 382:120-121.
-
(1996)
Nature
, vol.382
, pp. 120-121
-
-
Smith, M.A.1
Perry, G.2
Richey, P.L.3
Sayre, L.M.4
Anderson, V.E.5
Beal, M.F.6
Kowall, N.7
-
41
-
-
0033751421
-
Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease
-
Smith MA, Nunomura A, Zhu X, Takeda A, Perry G. 2000. Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease. Antioxid Redox Signal 2:413-420.
-
(2000)
Antioxid Redox Signal
, vol.2
, pp. 413-420
-
-
Smith, M.A.1
Nunomura, A.2
Zhu, X.3
Takeda, A.4
Perry, G.5
-
42
-
-
0015831449
-
Ascorbic acid homeostasis in the central nervous system
-
Spector R, Lorenzo AV. 1973. Ascorbic acid homeostasis in the central nervous system. Am J Physiol 225:751-763.
-
(1973)
Am J Physiol
, vol.225
, pp. 751-763
-
-
Spector, R.1
Lorenzo, A.V.2
-
43
-
-
0030799043
-
Low density lipoprotein oxidation and its pathobiological significance
-
Steinberg D. 1997. Low density lipoprotein oxidation and its pathobiological significance. J Biol Chem 272:20963-20966.
-
(1997)
J Biol Chem
, vol.272
, pp. 20963-20966
-
-
Steinberg, D.1
-
44
-
-
0028556264
-
Lipoprotein oxidation: Mechanistic aspects, methodological approaches and clinical relevance
-
Stocker R. 1994. Lipoprotein oxidation: mechanistic aspects, methodological approaches and clinical relevance. Curr Opin Lipidol 5:422-433.
-
(1994)
Curr Opin Lipidol
, vol.5
, pp. 422-433
-
-
Stocker, R.1
-
45
-
-
0031666630
-
Vitamin E and other endogenous antioxidants in the central nervous system
-
Vatassery GT. 1998. Vitamin E and other endogenous antioxidants in the central nervous system. Geriatrics 53 (suppl 1):S25-S27.
-
(1998)
Geriatrics
, vol.53
, Issue.SUPPL. 1
-
-
Vatassery, G.T.1
|