메뉴 건너뛰기




Volumn 5 E, Issue 1, 2013, Pages 167-177

Genetics of familial and sporadic Alzheimer's disease

Author keywords

Alzheimer's disease; Epigenetics; Genes mutation; GWAS; Review; Single nucleotide polymorphisms

Indexed keywords

AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; PRESENILIN 1; PRESENILIN 2; PRESENILIN;

EID: 84878486664     PISSN: 19450494     EISSN: 19450508     Source Type: Journal    
DOI: 10.2741/e605     Document Type: Article
Times cited : (183)

References (81)
  • 3
    • 77957927865 scopus 로고    scopus 로고
    • The genetics of Alzheimer disease: Back to the future
    • L. Bertram, C. M. Lill and R. E. Tanzi: The genetics of Alzheimer disease: back to the future. Neuron 68, 270-281 (2010)
    • (2010) Neuron , vol.68 , pp. 270-281
    • Bertram, L.1    Lill, C.M.2    Tanzi, R.E.3
  • 4
    • 0029899593 scopus 로고    scopus 로고
    • Incomplete penetrance of familial Alzheimer's disease in a pedigree with a novel presenilin-1 gene mutation [16]
    • M. N. Rossor, N. C. Fox, J. Beck, T. C. Campbell and J. Collinge: Incomplete penetrance of familial Alzheimer's disease in a pedigree with a novel presenilin-1 gene mutation. Lancet 347, 1560 (1996) (Pubitemid 26162664)
    • (1996) Lancet , vol.347 , Issue.9014 , pp. 1560
    • Rossor, M.N.1    Fox, N.C.2    Beck, J.3    Campbell, T.C.4    Collinge, J.5
  • 5
  • 6
    • 0021207461 scopus 로고
    • Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein
    • G. G. Glenner and C. W. Wong: Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem Biophys Res Commun 122, 1131-1135 (1984) (Pubitemid 14027629)
    • (1984) Biochemical and Biophysical Research Communications , vol.122 , Issue.3 , pp. 1131-1135
    • Glenner, G.G.1    Wong, C.W.2
  • 7
    • 13944276825 scopus 로고    scopus 로고
    • Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
    • DOI 10.1016/j.cell.2005.02.008
    • R. E. Tanzi and L. Bertram: Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 120, 545-555. (2005) (Pubitemid 40269768)
    • (2005) Cell , vol.120 , Issue.4 , pp. 545-555
    • Tanzi, R.E.1    Bertram, L.2
  • 8
    • 34548306686 scopus 로고    scopus 로고
    • The molecular link between β- and γ-secretase activity on the amyloid β precursor protein
    • DOI 10.1007/s00018-007-7219-3
    • M. Tabaton and E. Tamagno: The molecular link between beta-and gamma-secretase activity on the amyloid beta precursor protein. Cell Mol Life Sci 64, 2211-2218 (2007) (Pubitemid 47347960)
    • (2007) Cellular and Molecular Life Sciences , vol.64 , Issue.17 , pp. 2211-2218
    • Tabaton, M.1    Tamagno, E.2
  • 16
    • 32844465332 scopus 로고    scopus 로고
    • Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene
    • DOI 10.1007/s00415-005-0019-5
    • A. J. Larner and M. Doran: Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene. J Neurol 253, 139-158 (2006) (Pubitemid 43255883)
    • (2006) Journal of Neurology , vol.253 , Issue.2 , pp. 139-158
    • Larner, A.J.1    Doran, M.2
  • 17
    • 16644396131 scopus 로고    scopus 로고
    • Pathological and clinical heterogeneity of presenilin 1 gene mutations
    • M. Menéndez: Pathological and clinical heterogeneity of presenilin 1 gene mutations. J Alzheimers Dis. 6, 475-482 (2004) (Pubitemid 40916689)
    • (2004) Journal of Alzheimer's Disease , vol.6 , Issue.5 , pp. 475-482
    • Menendez, M.1
  • 18
    • 0031714867 scopus 로고    scopus 로고
    • Monogenic determinants of familial Alzheimer's disease: Presenilin-1 mutations
    • DOI 10.1007/s000180050219
    • D. M. Kovacs and R. E. Tanzi: Monogenic determinants of familial Alzheimer's disease: presenilin1 mutations. Cell Mol Life Sci 54, 902-909 (1998) (Pubitemid 28461678)
    • (1998) Cellular and Molecular Life Sciences , vol.54 , Issue.9 , pp. 902-909
    • Kovacs, D.M.1    Tanzi, R.E.2
  • 20
    • 77950815769 scopus 로고    scopus 로고
    • Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2
    • S. Jayadev, J. B. Leverenz, E. Steinbart, J. Stahl, W. Klunk, C. E. Yu and T. D. Bird: Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2. Brain 133, 1143-1154 (2010)
    • (2010) Brain , vol.133 , pp. 1143-1154
    • Jayadev, S.1    Leverenz, J.B.2    Steinbart, E.3    Stahl, J.4    Klunk, W.5    Yu, C.E.6    Bird, T.D.7
  • 21
    • 79951713725 scopus 로고    scopus 로고
    • Apolipoprotein E in Alzheimer's disease and other neurological disorders
    • P. B. Verghese, J. M. Castellano and D. M. Holtzman: Apolipoprotein E in Alzheimer's disease and other neurological disorders. Lancet Neurol 10, 241-252 (2011)
    • (2011) Lancet Neurol , vol.10 , pp. 241-252
    • Verghese, P.B.1    Castellano, J.M.2    Holtzman, D.M.3
  • 23
    • 33746565284 scopus 로고    scopus 로고
    • Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease
    • DOI 10.1038/sj.mp.4001854, PII 4001854
    • I. J. Martins, E. Hone, J. K. Foster, S. I. Sünram-Lea, A. Gnjec, S. J. Fuller, D. Nolan, S. E. Gandy and R. N. Martins: Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease. Mol Psychiatry 11, 721-736 (2006) (Pubitemid 44141805)
    • (2006) Molecular Psychiatry , vol.11 , Issue.8 , pp. 721-736
    • Martins, I.J.1    Hone, E.2    Foster, J.K.3    Sunram-Lea, S.I.4    Gnjec, A.5    Fuller, S.J.6    Nolan, D.7    Gandy, S.E.8    Martins, R.N.9
  • 26
    • 77953388335 scopus 로고    scopus 로고
    • Genetics of Alzheimer disease in the pre-and post-GWAS era
    • N. Ertekin-Taner: Genetics of Alzheimer disease in the pre-and post-GWAS era. Alzheimers Res Ther 2, 3 (2010)
    • (2010) Alzheimers Res Ther , vol.2 , pp. 3
    • Ertekin-Taner, N.1
  • 27
    • 68049148052 scopus 로고    scopus 로고
    • A genome-wide association study for late-onset alzheimer's disease using DNA pooling
    • R. Abraham, V. Moskvina, R. Sims, P. Hollingworth, A. Morgan, L. Georgieva, K. Dowzell, S. Cichon, A. M. Hillmer, M. C. O'Donovan, J. Williams, M. J. Owen and G. Kirov: A genome-wide association study for late-onset alzheimer's disease using DNA pooling. BMC Med Genomics 1, 44 (2008)
    • (2008) BMC Med Genomics , vol.1 , pp. 44
    • Abraham, R.1    Moskvina, V.2    Sims, R.3    Hollingworth, P.4    Morgan, A.5    Georgieva, L.6    Dowzell, K.7
  • 36
    • 79955484414 scopus 로고    scopus 로고
    • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
    • Alzheimer's Disease Neuroimaging Initiative, CHARGE Consortium, EADI1 Consortium, and
    • P. Hollingworth, D. Harold, R. Sims, A. Gerrish, J. C. Lambert, M. M. Carrasquillo, R. Abraham, M. L. Hamshere, J. S. Pahwa, V. Moskvina, K. Dowzell, N. Jones, A. Stretton, C. Thomas, A. Richards, D. Ivanov, C. Widdowson, J. Chapman, S. Lovestone, J. Powell, P. Proitsi, M. K. Lupton, C. Brayne, D. C. Rubinsztein, M. Gill, B. Lawlor, A. Lynch, K. S. Brown, P. A. Passmore, D. Craig, B. McGuinness, S. Todd, C. Holmes, D. Mann, A. D. Smith, H. Beaumont, D. Warden, G. Wilcock, S. Love, P. G. Kehoe, N. M. Hooper, E. R. Vardy, J. Hardy, S. Mead, N. C. Fox, M. Rossor, J. Collinge, W. Maier, F. Jessen, E. Rüther, B. Schürmann, R. Heun, H. Kölsch, H. van den Bussche, I. Heuser, J. Kornhuber, J. Wiltfang, M. Dichgans, L. Frölich, H. Hampel, J. Gallacher, M. Hüll, D. Rujescu, I. Giegling, A. M. Goate, J. S. Kauwe, C. Cruchaga, P. Nowotny, J. C. Morris, K. Mayo, K. Sleegers, K. Bettens, S. Engelborghs, PP. De Deyn, C. Van Broeckhoven, G. Livingston, N. J. Bass, H. Gurling, A. McQuillin, R. Gwilliam, P. Deloukas, A. Al-Chalabi, C. E. Shaw, M. Tsolaki, A. B. Singleton, R. Guerreiro, T. W. Mühleisen, M. M. Nöthen, S. Moebus, K. H. Jöckel, N. Klopp, H. E. Wichmann, V. S. Pankratz, S. B. Sando, J. O. Aasly, M. Barcikowska, Z. K. Wszolek, D. W. Dickson, N. R. Graff-Radford, R. C. Petersen, Alzheimer's Disease Neuroimaging Initiative, C. M. van Duijn, M. M. Breteler, M. A. Ikram, A. L. DeStefano, A. L. Fitzpatrick, O. Lopez, L. J. Launer, S. Seshadri, CHARGE Consortium, C. Berr, D. Campion, J. Epelbaum, J. F. Dartigues, C. Tzourio, A. Alpérovitch, M. Lathrop, EADI1 Consortium, T. M. Feulner, P. Friedrich, C. Riehle, M. Krawczak, S. Schreiber, M. Mayhaus, S. Nicolhaus, S. Wagenpfeil, S. Steinberg, H. Stefansson, K. Stefansson, J. Snaedal, S. Björnsson, P. V. Jonsson, V. Chouraki, B. Genier-Boley, M. Hiltunen, H. Soininen, O. Combarros, D. Zelenika, M. Delepine, M. J. Bullido, F. Pasquier, I. Mateo, A. Frank-Garcia, E. Porcellini, O. Hanon, E. Coto, V. Alvarez, P. Bosco, G. Siciliano, M. Mancuso, F. Panza, V. Solfrizzi, B. Nacmias, S. Sorbi, P. Bossù, P. Piccardi, B. Arosio, G. Annoni, D. Seripa, A. Pilotto, E. Scarpini, D. Galimberti, A. Brice, D. Hannequin, F. Licastro, L. Jones, P. A. Holmans, T. Jonsson, M. Riemenschneider, K. Morgan, S. G. Younkin, M. J. Owen, M. O'Donovan, P. Amouyel and J. Williams. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet 43, 429-435 (2011)
    • (2011) Nat Genet , vol.43 , pp. 429-435
    • Hollingworth, P.1    Harold, D.2    Sims, R.3    Gerrish, A.4    Lambert, J.C.5    Carrasquillo, M.M.6    Abraham, R.7    Hamshere, M.L.8    Pahwa, J.S.9    Moskvina, V.10    Dowzell, K.11    Jones, N.12    Stretton, A.13    Thomas, C.14    Richards, A.15    Ivanov, D.16    Widdowson, C.17    Chapman, J.18
  • 37
    • 79952089521 scopus 로고    scopus 로고
    • Metaanalysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with lateonset alzheimer's disease
    • Alzheimer's Disease Neuroimaging Initiative
    • X. Hu, E. Pickering, Y. C. Liu, S. Hall, H. Fournier, E. Katz, B. Dechairo, S. John, P. Van Eerdewegh, H. Soares and Alzheimer's Disease Neuroimaging Initiative. Metaanalysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with lateonset alzheimer's disease. PLoS One 6, e16616 (2011)
    • (2011) PLoS One , vol.6
    • Hu, X.1    Pickering, E.2    Liu, Y.C.3    Hall, S.4    Fournier, H.5    Katz, E.6    Dechairo, B.7    John, S.8    Van Eerdewegh, P.9    Soares, H.10
  • 40
    • 79955464911 scopus 로고    scopus 로고
    • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset alzheimer's disease
    • A. C. Naj, G. Jun, G. W. Beecham, L. S. Wang, B. N. Vardarajan, J. Buros, P. J. Gallins, J. D. Buxbaum, G. P. Jarvik, P. K. Crane, E. B. Larson, T. D. Bird, B. F. Boeve, N. R. Graff-Radford, P. L. De Jager, D. Evans, J. A. Schneider, M. M. Carrasquillo, N. Ertekin-Taner, S. G. Younkin, C. Cruchaga, J. S. Kauwe, P. Nowotny, P. Kramer, J. Hardy, M. J. Huentelman, A. J. Myers, M. M. Barmada, F. Y. Demirci, C. T. Baldwin, R. C. Green, E. Rogaeva, P. St George-Hyslop, S. E. Arnold, R. Barber, T. Beach, E. H. Bigio, J. D. Bowen, A. Boxer, J. R. Burke, N. J. Cairns, C. S. Carlson, R. M. Carney, S. L. Carroll, H. C. Chui, D. G. Clark, J. Corneveaux, C. W. Cotman, J. L. Cummings, C. Decarli, S. T. Dekosky, R. Diaz-Arrastia, M. Dick, D. W. Dickson, W. G. Ellis, K. M. Faber, K. B. Fallon, M. R. Farlow, S. Ferris, M. P. Frosch, D. R. Galasko, M. Ganguli, M. Gearing, D. H. Geschwind, B. Ghetti, J. R. Gilbert, S. Gilman, B. Giordani, J. D. Glass, J. H. Growdon, R. L. Hamilton, L. E. Harrell, E. Head, L. S. Honig, C. M. Hulette, B. T. Hyman, G. A. Jicha, L. W. Jin, N. Johnson, J. Karlawish, A. Karydas, J. A. Kaye, R. Kim, E. H. Koo, N. W. Kowall, J. J. Lah, A. I. Levey, A. P. Lieberman, O. L. Lopez, W. J. Mack, D. C. Marson, F. Martiniuk, D. C. Mash, E. Masliah, W. C. McCormick, S. M. McCurry, A. N. McDavid, A. C. McKee, M. Mesulam, B. L. Miller, C. A. Miller, J. W. Miller, J. E. Parisi, D. P. Perl, E. Peskind, R. C. Petersen, W. W. Poon, J. F. Quinn, R. A. Rajbhandary, M. Raskind, B. Reisberg, J. M. Ringman, E. D. Roberson, R. N. Rosenberg, M. Sano, L. S. Schneider, W. Seeley, M. L. Shelanski, M. A. Slifer, C. D. Smith, J. A. Sonnen, S. Spina, R. A. Stern, R. E. Tanzi, J. Q. Trojanowski, J. C. Troncoso, V. M. Van Deerlin, H. V. Vinters, J. P. Vonsattel, S. Weintraub, K. A. Welsh-Bohmer, J. Williamson, R. L. Woltjer, L. B. Cantwell, B. A. Dombroski, D. Beekly, K. L. Lunetta, E. R. Martin, M. I. Kamboh, A. J. Saykin, E. M. Reiman, D. A. Bennett, J. C. Morris, T. J. Montine, A. M. Goate, D. Blacker, D. W. Tsuang, H. Hakonarson, W. A. Kukull, T. M. Foroud, J. L. Haines, R. Mayeux, M. A. Pericak-Vance, L. A. Farrer and G. D. Schellenberg: Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset alzheimer's disease. Nat Genet 43, 436-441 (2011)
    • (2011) Nat Genet , vol.43 , pp. 436-441
    • Naj, A.C.1    Jun, G.2    Beecham, G.W.3    Wang, L.S.4    Vardarajan, B.N.5    Buros, J.6    Gallins, P.J.7    Buxbaum, J.D.8    Jarvik, G.P.9    Crane, P.K.10
  • 41
    • 58849104938 scopus 로고    scopus 로고
    • Genome screen of late-onset alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis
    • S. E. Poduslo, R. Huang, J. Huang and S. Smith. Genome screen of late-onset alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis. Am J Med Genet B Neuropsychiatr Genet 150B, 50-55 (2009)
    • (2009) Am J Med Genet B Neuropsychiatr Genet , vol.150 B , pp. 50-55
    • Poduslo, S.E.1    Huang, R.2    Huang, J.3    Smith, S.4
  • 42
    • 68449089420 scopus 로고    scopus 로고
    • Alzheimer's Disease Neuroimaging Initiative. Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease
    • S. G. Potkin, G. Guffanti, A. Lakatos, J. A. Turner, F. Kruggel, J. H. Fallon, A. J. Saykin, A. Orro, S. Lupoli, E. Salvi, M. Weiner, F. Macciardi and Alzheimer's Disease Neuroimaging Initiative. Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease. PLoS One 4, e6501 (2009)
    • (2009) PLoS One , vol.4
    • Potkin, S.G.1    Guffanti, G.2    Lakatos, A.3    Turner, J.A.4    Kruggel, F.5    Fallon, J.H.6    Saykin, A.J.7    Orro, A.8    Lupoli, S.9    Salvi, E.10    Weiner, M.11    Macciardi, F.12
  • 49
    • 34248142174 scopus 로고    scopus 로고
    • Comprehensive analysis of APOE and selected proximate markers for late-onset Alzheimer's disease: Patterns of linkage disequilibrium and disease/marker association
    • DOI 10.1016/j.ygeno.2007.02.002, PII S088875430700050X
    • C. E. Yu, H. Seltman, E. R. Peskind, N. Galloway, P. X. Zhou, E. Rosenthal, E. M. Wijsman, D. W. Tsuang, B. Devlin and G. D. Schellenberg: Comprehensive analysis of APOE and selected proximate markers for late-onset alzheimer's disease: patterns of linkage disequilibrium and disease/marker association. Genomics 89, 655-665 (2007) (Pubitemid 46719797)
    • (2007) Genomics , vol.89 , Issue.6 , pp. 655-665
    • Yu, C.-E.1    Seltman, H.2    Peskind, E.R.3    Galloway, N.4    Zhou, P.X.5    Rosenthal, E.6    Wijsman, E.M.7    Tsuang, D.W.8    Devlin, B.9    Schellenberg, G.D.10
  • 50
    • 79959396151 scopus 로고    scopus 로고
    • The three new pathways leading to Alzheimer's disease
    • K. Morgan: The three new pathways leading to Alzheimer's disease. Neuropathol Appl Neurobiol 37, 353-357 (2011)
    • (2011) Neuropathol Appl Neurobiol , vol.37 , pp. 353-357
    • Morgan, K.1
  • 51
    • 0026537880 scopus 로고
    • Distribution of clusterin in Alzheimer brain tissue
    • P. L. McGeer, T. Kawamata and D. G. Walker: Distribution of clusterin in Alzheimer brain tissue. Brain Res 579, 337-341 (1992)
    • (1992) Brain Res , vol.579 , pp. 337-341
    • McGeer, P.L.1    Kawamata, T.2    Walker, D.G.3
  • 52
    • 33646492644 scopus 로고    scopus 로고
    • Clusterin in cerebrospinal fluid: Analysis of carbohydrates and quantification of native and glycosylated forms
    • A. M. Nilselid, P. Davidsson, K. Nägga, N. Andreasen, P. Fredman and K. Blennow: Clusterin in cerebrospinal fluid: analysis of carbohydrates and quantification of native and glycosylated forms. Neurochem Int 48, 718-728 (2006)
    • (2006) Neurochem Int , vol.48 , pp. 718-728
    • Nilselid, A.M.1    Davidsson, P.2    Nägga, K.3    Andreasen, N.4    Fredman, P.5    Blennow, K.6
  • 53
    • 0035890306 scopus 로고    scopus 로고
    • Multiple receptors mediate apoJ-dependent clearance of cellular debris into nonprofessional phagocytes
    • DOI 10.1006/excr.2001.5358
    • M. M. Bartl, T. Luckenbach, O. Bergner, O. Ullrich and C. Koch-Brandt; Multiple receptors mediate apoJ-dependent clearance of cellular debris into nonprofessional phagocytes. Exp Cell Res 271, 130-141 (2001) (Pubitemid 33071000)
    • (2001) Experimental Cell Research , vol.271 , Issue.1 , pp. 130-141
    • Bartl, M.M.1    Luckenbach, T.2    Bergner, O.3    Ullrich, O.4    Koch-Brandt, C.5
  • 54
    • 34247506244 scopus 로고    scopus 로고
    • Transport pathways for clearance of human Alzheimer's amyloid β-peptide and apolipoproteins E and J in the mouse central nervous system
    • DOI 10.1038/sj.jcbfm.9600419, PII 9600419
    • R. D. Bell, A. P. Sagare, A. E. Friedman, G. S. Bedi, D. M. Holtzman, R. Deane and B. V. Zlokovic: Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system. J Cereb Blood Flow Metab 27, 909-918 (2007) (Pubitemid 46659038)
    • (2007) Journal of Cerebral Blood Flow and Metabolism , vol.27 , Issue.5 , pp. 909-918
    • Bell, R.D.1    Sagare, A.P.2    Friedman, A.E.3    Bedi, G.S.4    Holtzman, D.M.5    Deane, R.6    Zlokovic, B.V.7
  • 55
    • 0032807691 scopus 로고    scopus 로고
    • Clathrin assembly lymphoid myeloid leukemia (CALM) protein: Localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic
    • F. Tebar, S. K. Bohlander and A. Sorkin: Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrinmediated traffic. Mol Biol Cell 10, 2687-2702 (1999) (Pubitemid 29393520)
    • (1999) Molecular Biology of the Cell , vol.10 , Issue.8 , pp. 2687-2702
    • Tebar, F.1    Bohlander, S.K.2    Sorkin, A.3
  • 56
    • 38849199843 scopus 로고    scopus 로고
    • Evidence for calm in directing vamp2 trafficking
    • DOI 10.1111/j.1600-0854.2007.00694.x
    • A. Harel, F. Wu, M. P. Mattson, C. M. Morris, P. J. Yao: Evidence for CALM in directing VAMP2 trafficking. Traffic 9, 417-429 (2008) (Pubitemid 351189000)
    • (2008) Traffic , vol.9 , Issue.3 , pp. 417-429
    • Harel, A.1    Wu, F.2    Mattson, M.P.3    Morris, C.M.4    Yao, P.J.5
  • 57
    • 59249097049 scopus 로고    scopus 로고
    • Complement Receptor 1: Disease associations and therapeutic implications
    • R. Khera and N. Das: Complement Receptor 1: disease associations and therapeutic implications. Mol Immunol 46, 761-772 (2009)
    • (2009) Mol Immunol , vol.46 , pp. 761-772
    • Khera, R.1    Das, N.2
  • 58
    • 54249166970 scopus 로고    scopus 로고
    • Synaptic vesicle endocytosis: Fast and slow modes of membrane retrieval
    • S. M. Smith, R. Renden, H. von Gersdorff: Synaptic vesicle endocytosis: fast and slow modes of membrane retrieval. Trends Neurosci 31, 559-68 (2008)
    • (2008) Trends Neurosci , vol.31 , pp. 559-568
    • Smith, S.M.1    Renden, R.2    Von Gersdorff, H.3
  • 59
    • 57649096298 scopus 로고    scopus 로고
    • The membrane-tubulating potential of amphiphysin 2/BIN1 is dependent on the microtubulebinding cytoplasmic linker protein 170 (CLIP-170)
    • B. Meunier, M. Quaranta, L. Daviet, A. Hatzoglou and C. Leprince: The membrane-tubulating potential of amphiphysin 2/BIN1 is dependent on the microtubulebinding cytoplasmic linker protein 170 (CLIP-170). Eur J Cell Biol 88, 91-102 (2009)
    • (2009) Eur J Cell Biol , vol.88 , pp. 91-102
    • Meunier, B.1    Quaranta, M.2    Daviet, L.3    Hatzoglou, A.4    Leprince, C.5
  • 60
    • 39749104095 scopus 로고    scopus 로고
    • Role of ATP-binding cassette transporters in brain lipid transport and neurological disease
    • DOI 10.1111/j.1471-4159.2007.05099.x
    • W. S. Kim, C. S. Weickert and B. Garner: Role of ATPbinding cassette transporters in brain lipid transport and neurological disease. J. Neurochem 104, 1145-1166 (2008) (Pubitemid 351293350)
    • (2008) Journal of Neurochemistry , vol.104 , Issue.5 , pp. 1145-1166
    • Kim, W.S.1    Weickert, C.S.2    Garner, B.3
  • 61
    • 13544251745 scopus 로고    scopus 로고
    • Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels
    • DOI 10.1074/jbc.M412602200
    • W. S. Kim, M. L. Fitzgerald, K. Kang, K. Okuhira, S. A. Bell, J. J. Manning, S. L. Koehn, N. Lu, K. J. Moore, M. W. Freeman: Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels. J Biol Chem 280, 3989-3995 (2005) (Pubitemid 40223868)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.5 , pp. 3989-3995
    • Kim, W.S.1    Fitzgerald, M.L.2    Kang, K.3    Okuhira, K.-I.4    Bell, S.A.5    Manning, J.J.6    Koehn, S.L.7    Lu, N.8    Moore, K.J.9    Freeman, M.W.10
  • 62
    • 33745054649 scopus 로고    scopus 로고
    • Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells
    • DOI 10.1097/01.wnr.0000221833.41340.cd, PII 0000175620060626000009
    • W. S. Kim, G. J. Guillemin, E. N. Glaros, C. K. Lim and B. Garner: Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells. Neuroreport 17, 891-896 (2006) (Pubitemid 43869954)
    • (2006) NeuroReport , vol.17 , Issue.9 , pp. 891-896
    • Kim, W.S.1    Guillemin, G.J.2    Glaros, E.N.3    Lim, C.K.4    Garner, B.5
  • 64
    • 34547855087 scopus 로고    scopus 로고
    • Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity
    • DOI 10.1128/MCB.00383-07
    • H. Tateno, H. Li, M. J. Schur, N. Bovin, P. R. Crocker, W. W. Wakarchuk and J. C. Paulson: Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity. Mol Cell Biol 27, 5699-5710 (2007) (Pubitemid 47257827)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.16 , pp. 5699-5710
    • Tateno, H.1    Li, H.2    Schur, M.J.3    Bovin, N.4    Crocker, P.R.5    Wakarchuk, W.W.6    Paulson, J.C.7
  • 65
    • 33947602811 scopus 로고    scopus 로고
    • Siglecs and their roles in the immune system
    • DOI 10.1038/nri2056, PII NRI2056
    • P. R. Crocker, J. C. Paulson and A. Varki: Siglecs and their roles in the immune system. Nat Rev Immunol. 7, 255-266 (2007) (Pubitemid 46480955)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.4 , pp. 255-266
    • Crocker, P.R.1    Paulson, J.C.2    Varki, A.3
  • 66
    • 23844508516 scopus 로고    scopus 로고
    • Functions of ephrin/Eph interactions in the development of the nervous system: Emphasis on the hippocampal system
    • DOI 10.1016/j.brainresrev.2005.02.001, PII S0165017305000275, Embryonic Chimeras and Transplantation for the Study of CNS Development and Regeneration
    • A. Martinez and E. Soriano: Functions of ephrin/Eph interactions in the development of the nervous system: emphasis on the hippocampal system. Brain Res Brain Res Rev 49, 211-226 (2005) (Pubitemid 41160391)
    • (2005) Brain Research Reviews , vol.49 , Issue.2 , pp. 211-226
    • Martinez, A.1    Soriano, E.2
  • 67
    • 68649122864 scopus 로고    scopus 로고
    • Synapse development and plasticity: Roles of ephrin/Eph receptor signaling
    • K. O. Lai and N. Y. Ip: Synapse development and plasticity: roles of ephrin/Eph receptor signaling. Curr Opin Neurobiol 19, 275-283 (2009)
    • (2009) Curr Opin Neurobiol , vol.19 , pp. 275-283
    • Lai, K.O.1    Ip, N.Y.2
  • 68
    • 0038498066 scopus 로고    scopus 로고
    • A cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton
    • DOI 10.1074/jbc.M211407200
    • D. K. Lynch, S. C. Winata, R. J. Lyons, W. E. Hughes, G. M. Lehrbach, V. Wasinger, G. Corthals, S. Cordwell and R. J. Daly: A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton. J Biol Chem 278, 21805-21813 (2003) (Pubitemid 36792585)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.24 , pp. 21805-21813
    • Lynch, D.K.1    Winata, S.C.2    Lyons, R.J.3    Hughes, W.E.4    Lehrbach, G.M.5    Wasinger, V.6    Corthals, G.7    Cordwell, S.8    Daly, R.J.9
  • 69
    • 0036810492 scopus 로고    scopus 로고
    • Functions and malfunctions of the tau proteins
    • N. Shahani and R. Brandt: Functions and malfunctions of the tau proteins. Cell Mol Life Sci 59, 1668-1680 (2002) (Pubitemid 35346971)
    • (2002) Cellular and Molecular Life Sciences , vol.59 , Issue.10 , pp. 1668-1680
    • Shahani, N.1    Brandt, R.2
  • 70
    • 0042697305 scopus 로고    scopus 로고
    • Triple-transgenic model of Alzheimer's Disease with plaques and tangles: Intracellular Aβ and synaptic dysfunction
    • DOI 10.1016/S0896-6273(03)00434-3
    • S. Oddo, A. Caccamo, J. D. Shepherd, M. P. Murphy, T. E. Golde, R. Kayed, R. Metherate, M. P. Mattson, Y. Akbari, and F. M. LaFerla: Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 39, 409-421 (2003) (Pubitemid 36937044)
    • (2003) Neuron , vol.39 , Issue.3 , pp. 409-421
    • Oddo, S.1    Caccamo, A.2    Shepherd, J.D.3    Murphy, M.P.4    Golde, T.E.5    Kayed, R.6    Metherate, R.7    Mattson, M.P.8    Akbari, Y.9    LaFerla, F.M.10
  • 72
    • 34250335127 scopus 로고    scopus 로고
    • Functional MAPT haplotypes: Bridging the gap between genotype and neuropathology
    • DOI 10.1016/j.nbd.2007.04.006, PII S0969996107000940
    • T. M. Caffrey and R. Wade-Martins: Functional MAPT haplotypes: bridging the gap between genotype and neuropathology. Neurobiol Dis 27, 1-10 (2007) (Pubitemid 46921479)
    • (2007) Neurobiology of Disease , vol.27 , Issue.1 , pp. 1-10
    • Caffrey, T.M.1    Wade-Martins, R.2
  • 73
    • 35348875469 scopus 로고    scopus 로고
    • Familial early-onset dementia with tau intron 10 + 16 mutation with clinical features similar to those of Alzheimer disease
    • DOI 10.1001/archneur.64.10.1535
    • M. Doran, D. G. du Plessis, E. J. Ghadiali, D. M. Mann, S. Pickering-Brown and A. J. Larner: Familial early-onset dementia with tau intron 10 + 16 mutation with clinical features similar to those of Alzheimer disease. Arch Neurol 64, 1535-1539 (2007) (Pubitemid 47572682)
    • (2007) Archives of Neurology , vol.64 , Issue.10 , pp. 1535-1539
    • Doran, M.1    Du Plessis, D.G.2    Ghadiali, E.J.3    Mann, D.M.A.4    Pickering-Brown, S.5    Larner, A.J.6
  • 74
    • 46249115694 scopus 로고    scopus 로고
    • Mutation negative "early-onset familial Alzheimer disease": Consider screening for tau gene mutations
    • A. J. Larner: Mutation negative "early-onset familial Alzheimer disease": consider screening for tau gene mutations. Alzheimer Dis Assoc Disord. 22, 194-195 (2008)
    • (2008) Alzheimer Dis Assoc Disord , vol.22 , pp. 194-195
    • Larner, A.J.1
  • 79
    • 77954552201 scopus 로고    scopus 로고
    • Evidence linking genetics, environment, and epigenetics to impaired DNA repair in Alzheimer's disease
    • F. Coppedè and L. Migliore: Evidence linking genetics, environment, and epigenetics to impaired DNA repair in Alzheimer's disease. J Alzheimers Dis 20, 953-966 (2010)
    • (2010) J Alzheimers Dis , vol.20 , pp. 953-966
    • Coppedè, F.1    Migliore, L.2
  • 81
    • 0023103748 scopus 로고
    • The genetic defect causing familial Alzheimer's disease maps on chromosome 21
    • P. H. St George-Hyslop, R. E. Tanzi, R. J. Polinski, J. L. Haines, L. Nee, P. C. Watkins, R. H. Myers, R. G. Feldman, D. Pollen, D. Drachman: The genetic defect causing familial Alzheimer's disease maps on chromosome 21. Science 235, 885-90 (1987) (Pubitemid 17019126)
    • (1987) Science , vol.235 , Issue.4791 , pp. 885-890
    • St George-Hyslop, P.H.1    Tanzi, R.E.2    Polinsky, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.