Hydroxylated and non-hydroxylated sulfatide are distinctly distributed in the human cerebral cortex

Neuroscience

Volumn 193, Issue , 2011, Pages 44-53

  Yuki, D ^a   Sugiura, Y ^b   Zaima, N ^b,c   Akatsu, H ^d   Hashizume, Y ^d   Yamamoto, T ^d   Fujiwara, M ^a   Sugiyama, K ^a,e   Setou, M ^b  

^a LION CORPORATION   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KINKI UNIVERSITY   (Japan)

^d Fukushimura Hospital   (Japan)

^e RITSUMEIKAN UNIVERSITY   (Japan)

Author keywords

Alzheimer's disease; Cerebral cortex; Hydroxylation; Imaging mass spectrometry; Myelin sheath; Sulfatide

Indexed keywords

AMINOACRIDINE; HYDROXYLATED SULFATIDE; NONHYDROXYLATED SULFATIDE; SULFATIDE; UNCLASSIFIED DRUG;

AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN CORTEX; BRAIN FUNCTION; BRAIN NERVE CELL; CASE REPORT; CELLULAR DISTRIBUTION; CLINICAL ASSESSMENT; CONTROLLED STUDY; FATTY ACID METABOLISM; FEMALE; GRAY MATTER; HUMAN; HUMAN TISSUE; HYDROXYLATION; LIPID ANALYSIS; LIPID BRAIN LEVEL; LIPID COMPOSITION; LIPOGENESIS; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MYELIN SHEATH; OLIGODENDROGLIA; PATHOLOGY; PRIORITY JOURNAL; WHITE MATTER;

AGED, 80 AND OVER; ALZHEIMER DISEASE; AMIDOHYDROLASES; BRAIN MAPPING; CEREBRAL CORTEX; FEMALE; HUMANS; MALE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SULFOGLYCOSPHINGOLIPIDS; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION;

EID: 80052488002     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.07.045     Document Type: Article

References (43)

1. Alderson N.L., Maldonado E.N., Kern M.J., Bhat N.R., Hama H. FA2H-dependent fatty acid 2-hydroxylation in postnatal mouse brain. J Lipid Res 2006, 47:2772-2780.
2. Alderson N.L., Rembiesa B.M., Walla M.D., Bielawska A., Bielawski J., Hama H. The human FA2H gene encodes a fatty acid 2-hydroxylase. J Biol Chem 2004, 279:48562-48568.
3. Bansal R., Pfeiffer S.E. Reversible inhibition of oligodendrocyte progenitor differentiation by a monoclonal antibody against surface galactolipids. Proc Natl Acad Sci U S A 1989, 86:6181-6185.
4. Bansal R., Winkler S., Bheddah S. Negative regulation of oligodendrocyte differentiation by galactosphingolipids. J Neurosci 1999, 19:7913-7924.
5. Bosio A., Binczek E., Stoffel W. Functional breakdown of the lipid bilayer of the myelin membrane in central and peripheral nervous system by disrupted galactocerebroside synthesis. Proc Natl Acad Sci U S A 1996, 93:13280-13285.
6. Braak H., Braak E. Development of Alzheimer-related neurofibrillary changes in the neocortex inversely recapitulates cortical myelogenesis. Acta Neuropathol 1996, 92:197-201.
7. Cheng H., Sun G., Yang K., Gross R.W., Han X. Selective desorption/ionization of sulfatides by MALDI-MS facilitated using 9-aminoacridine as matrix. J Lipid Res 2010, 51:1599-1609.
8. Cherayil G.D. Fatty acid composition of brain glycolipids in Alzheimer's disease, senile dementia, and cerebrocortical atrophy. J Lipid Res 1968, 9:207-214.
9. Coetzee T., Fujita N., Dupree J., Shi R., Blight A., Suzuki K., Suzuki K., Popko B. Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability. Cell 1996, 86:209-219.
10. Dupree J.L., Coetzee T., Suzuki K., Popko B. Myelin abnormalities in mice deficient in galactocerebroside and sulfatide. J Neurocytol 1998, 27:649-659.
11. Eckhardt M., Hedayati K.K., Pitsch J., Lüllmann-Rauch R., Beck H., Fewou S.N., Gieselmann V. Sulfatide storage in neurons causes hyperexcitability and axonal degeneration in a mouse model of metachromatic leukodystrophy. J Neurosci 2007, 27:9009-9021.
12. Eckhardt M., Yaghootfam A., Fewou S.N., Zöller I., Gieselmann V. A mammalian fatty acid hydroxylase responsible for the formation of alpha-hydroxylated galactosylceramide in myelin. Biochem J 2005, 388:245-254.
13. Edvardson S., Hama H., Shaag A., Gomori J.M., Berger I., Soffer D., Korman S.H., Taustein I., Saada A., Elpeleg O. Mutations in the fatty acid 2-hydroxylase gene are associated with leukodystrophy with spastic paraparesis and dystonia. Am J Hum Genet 2008, 83:643-648.
14. Fewou S.N., Büssow H., Schaeren-Wiemers N., Vanier M.T., Macklin W.B., Gieselmann V., Eckhardt M. Reversal of non-hydroxy:α-hydroxy galactosylceramide ratio and unstable myelin in transgenic mice overexpressing UDP-galactose:ceramide galactosyltransferase. J Neurochem 2005, 94:469-481.
15. Foulon V., Sniekers M., Huysmans E., Asselberghs S., Mahieu V., Mannaerts G.P., Van Veldhoven P.P., Casteels M. Breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-CoA lyase: a revised pathway for the alpha-oxidation of straight chain fatty acids. J Biol Chem 2005, 280:9802-9812.
16. Fredman P., Mattsson L., Andersson K., Davidsson P., Ishizuka I., Jeansson S., Månsson J.E., Svennerholm L. Characterization of the binding epitope of a monoclonal antibody to sulphatide. Biochem J 1988, 251:17-22.
17. Goto-Inoue N., Hayasaka T., Sugiura Y., Taki T., Li Y.T., Matsumoto M., Setou M. High-sensitivity analysis of glycosphingolipids by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight imaging mass spectrometry on transfer membranes. J Chromatogr B Analyt Technol Biomed Life Sci 2008, 870:74-83.
18. Hama H. Fatty acid 2-hydroxylation in mammalian sphingolipid biology. Biochim Biophys Acta 2010, 1801:405-414.
19. Han X., Holtzman D.M., McKeel D.W., Kelley J., Morris J.C. Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis. J Neurochem 2002, 82:809-818.
20. Hermansson M., Käkelä R., Berghäll M., Lehesjoki A.E., Somerharju P., Lahtinen U. Mass spectrometric analysis reveals changes in phospholipid, neutral sphingolipid and sulfatide molecular species in progressive epilepsy with mental retardation, EPMR, brain: a case study. J Neurochem 2005, 95:609-617.
21. Honke K., Hirahara Y., Dupree J., Suzuki K., Popko B., Fukushima K., Fukushima J., Nagasawa T., Yoshida N., Wada Y., Taniguchi N. Paranodal junction formation and spermatogenesis require sulfoglycolipids. Proc Natl Acad Sci U S A 2002, 99:4227-4232.
22. Hoshi M., Williams M., Kishimoto Y. Characterization of brain cerebrosides at early stages of development in the rat. J Neurochem 1973, 21:709-712.
23. Hsu F.F., Bohrer A., Turk J. Electrospray ionization tandem mass spectrometric analysis of sulfatide. Determination of fragmentation patterns and characterization of molecular species expressed in brain and in pancreatic islets. Biochim Biophys Acta 1998, 1392:202-216.
24. Ikeda K., Shimizu T., Taguchi R. Targeted analysis of ganglioside and sulfatide molecular species by LC/ESI-MS/MS with theoretically expanded multiple reaction monitoring. J Lipid Res 2008, 49:2678-2689.
25. Ikeda K., Taguchi R. Highly sensitive localization analysis of gangliosides and sulfatides including structural isomers in mouse cerebellum sections by combination of laser microdissection and hydrophilic interaction liquid chromatography/electrospray ionization mass spectrometry with theoretically expanded multiple reaction monitoring. Rapid Commun Mass Spectrom 2010, 24:2957-2965.
26. Isaac G., Pernber Z., Gieselmann V., Hansson E., Bergquist J., Månsson J.E. Sulfatide with short fatty acid dominates in astrocytes and neurons. FEBS J 2006, 273:1782-1790.
27. Ishibashi T., Dupree J.L., Ikenaka K., Hirahara Y., Honke K., Peles E., Popko B., Suzuki K., Nishino H., Baba H. A myelin galactolipid, sulfatide, is essential for maintenance of ion channels on myelinated axon but not essential for initial cluster formation. J Neurosci 2002, 22:6507-6514.
28. Majocha R.E., Jungalwala F.B., Rodenrys A., Marotta C.A. Monoclonal antibody to embryonic CNS antigen A2B5 provides evidence for the involvement of membrane components at sites of Alzheimer degeneration and detects sulfatides as well as gangliosides. J Neurochem 1989, 53:953-961.
29. Marbois B.N., Faull K.F., Fluharty A.L., Raval-Fernandes S., Rome L.H. Analysis of sulfatide from rat cerebellum and multiple sclerosis white matter by negative ion electrospray mass spectrometry. Biochim Biophys Acta 2000, 1484:59-70.
30. Marcus J., Popko B. Galactolipids are molecular determinants of myelin development and axo-glial organization. Biochim Biophys Acta 2002, 1573:406-413.
31. Mitew S., Kirkcaldie M.T., Halliday G.M., Shepherd C.E., Vickers J.C., Dickson T.C. Focal demyelination in Alzheimer's disease and transgenic mouse models. Acta Neuropathol 2010, 119:567-577.
32. Murphy R.C., Hankin J.A., Barkley R.M. Imaging of lipid species by MALDI mass spectrometry. J Lipid Res 2009, 50(Suppl):S317-S322.
33. Norton W.T., Autilio L.A. The chemical composition of bovine CNS myelin. Ann N Y Acad Sci 1965, 122:77-85.
34. Plourde M., Fortier M., Vandal M., Tremblay-Mercier J., Freemantle E., Bégin M., Pifferi F., Cunnane S.C. Unresolved issues in the link between docosahexaenoic acid and Alzheimer's disease. Prostaglandins Leukot Essent Fatty Acids 2007, 77:301-308.
35. Pulfer M., Murphy R.C. Electrospray mass spectrometry of phospholipids. Mass Spectrom Rev 2003, 22:332-364.
36. Ramakrishnan H., Hedayati K.K., Lüllmann-Rauch R., Wessig C., Fewou S.N., Maier H., Goebel H.H., Gieselmann V., Eckhardt M. Increasing sulfatide synthesis in myelin-forming cells of arylsulfatase A-deficient mice causes demyelination and neurological symptoms reminiscent of human metachromatic leukodystrophy. J Neurosci 2007, 27:9482-9490.
37. Schaeren-Wiemers N., van der Bijl P., Schwab M.E. The UDP-galactose:ceramide galactosyltransferase: expression pattern in oligodendrocytes and Schwann cells during myelination and substrate preference for hydroxyceramide. J Neurochem 1995, 65:2267-2278.
38. Schwartz S.A., Reyzer M.L., Caprioli R.M. Direct tissue analysis using matrix-assisted laser desorption/ionization mass spectrometry: practical aspects of sample preparation. J Mass Spectrom 2003, 38:699-708.
39. Shimma S., Sugiura Y., Hayasaka T., Hoshikawa Y., Noda T., Setou M. MALDI-based imaging mass spectrometry revealed abnormal distribution of phospholipids in colon cancer liver metastasis. J Chromatogr B Analyt Technol Biomed Life Sci 2007, 855:98-103.
40. Sugiura Y., Konishi Y., Zaima N., Kajihara S., Nakanishi H., Taguchi R., Setou M. Visualization of the cell-selective distribution of PUFA-containing phosphatidylcholines in mouse brain by imaging mass spectrometry. J Lipid Res 2009, 50:1776-1788.
41. Sugiura Y., Shinna S., Setou M. Thin sectioning improves the peak intensity and signal-to-noise ratio in direct tissue mass spectrometry. J Mass Spectrom Soc Jpn 2006, 54:45-48.
42. Veloso A., Fernández R., Astigarraga E., Barreda-Gómez G., Manuel I., Giralt M.T., Ferrer I., Ochoa B., Rodríguez-Puertas R., Fernández J.A. Distribution of lipids in human brain. Anal Bioanal Chem 2011, 401:89-101.
43. Zöller I., Meixner M., Hartmann D., Büssow H., Meyer R., Gieselmann V., Eckhardt M. Absence of 2-hydroxylated sphingolipids is compatible with normal neural development but causes late-onset axon and myelin sheath degeneration. J Neurosci 2008, 28:9741-9754.