Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate- synthase by amyloid precursor protein processing and is affected in Alzheimer's disease

Journal of Neurochemistry

Volumn 116, Issue 5, 2011, Pages 916-925

  Grimm, Marcus O W ^a   Kuchenbecker, Johanna ^a   Rothhaar, Tatjana L ^a   Grösgen, Sven ^a   Hundsdörfer, Benjamin ^a   Burg, Verena K ^a   Friess, Petra ^a   Müller, Ulrike ^b   Grimm, Heike S ^a   Riemenschneider, Mathias ^a,c   Hartmann, Tobias ^a,d  

^a Neurodegeneration and Neurobiology   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c Deutsches Institut für DemenzPrävention DIDP   (Germany)

^d Experimental Neurology Medical Campus of the Saarland University   (Germany)

Author keywords

alkyl dihydroxyacetonephosphate synthase; Alzheimer's disease; amyloid beta; APP intracellular domain; plasmalogens; reactive oxidative species

Indexed keywords

ALKYLGLYCERONE PHOSPHATE SYNTHASE; AMYLOID PRECURSOR PROTEIN; DIHYDROXYACETONE PHOSPHATE; PLASMALOGEN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN REGION; CONTROLLED STUDY; FRONTAL CORTEX; HOMEOSTASIS; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; LIPID PEROXIDATION; LIPOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METABOLISM;

ALKYL AND ARYL TRANSFERASES; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; CELL LINE; CYTIDINE DEAMINASE; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; MALE; MICE; MICE, KNOCKOUT; MUTATION; NEUROBLASTOMA; OXIDATIVE STRESS; PLASMALOGENS; REACTIVE OXYGEN SPECIES; TRANSFECTION;

EID: 79851471469     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.07070.x     Document Type: Article

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