-
1
-
-
73949133588
-
Role of HIV membrane in neutralization by two broadly neutralizing antibodies
-
S.M. Alam, M. Morelli, S.M. Dennison, H.X. Liao, R. Zhang, S.M. Xia, S. Rits-Volloch, L. Sun, S.C. Harrison, B.F. Haynes, and B. Chen Role of HIV membrane in neutralization by two broadly neutralizing antibodies Proc. Natl. Acad. Sci. USA 106 2009 20234 20239
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 20234-20239
-
-
Alam, S.M.1
Morelli, M.2
Dennison, S.M.3
Liao, H.X.4
Zhang, R.5
Xia, S.M.6
Rits-Volloch, S.7
Sun, L.8
Harrison, S.C.9
Haynes, B.F.10
Chen, B.11
-
2
-
-
80655143478
-
Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation
-
S.M. Alam, H.X. Liao, S.M. Dennison, F. Jaeger, R. Parks, K. Anasti, A. Foulger, M. Donathan, J. Lucas, and L. Verkoczy et al. Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation J. Virol. 85 2011 11725 11731
-
(2011)
J. Virol.
, vol.85
, pp. 11725-11731
-
-
Alam, S.M.1
Liao, H.X.2
Dennison, S.M.3
Jaeger, F.4
Parks, R.5
Anasti, K.6
Foulger, A.7
Donathan, M.8
Lucas, J.9
Verkoczy, L.10
-
3
-
-
84887315888
-
Recognition of synthetic glycopeptides by HIV-1 broadly neutralizing antibodies and their unmutated ancestors
-
S.M. Alam, S.M. Dennison, B. Aussedat, Y. Vohra, P.K. Park, A. Fernández-Tejada, S. Stewart, F.H. Jaeger, K. Anasti, and J.H. Blinn et al. Recognition of synthetic glycopeptides by HIV-1 broadly neutralizing antibodies and their unmutated ancestors Proc. Natl. Acad. Sci. USA 110 2013 18214 18219
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 18214-18219
-
-
Alam, S.M.1
Dennison, S.M.2
Aussedat, B.3
Vohra, Y.4
Park, P.K.5
Fernández-Tejada, A.6
Stewart, S.7
Jaeger, F.H.8
Anasti, K.9
Blinn, J.H.10
-
4
-
-
84855466746
-
Antibody-based protection against HIV infection by vectored immunoprophylaxis
-
A.B. Balazs, J. Chen, C.M. Hong, D.S. Rao, L. Yang, and D. Baltimore Antibody-based protection against HIV infection by vectored immunoprophylaxis Nature 481 2012 81 84
-
(2012)
Nature
, vol.481
, pp. 81-84
-
-
Balazs, A.B.1
Chen, J.2
Hong, C.M.3
Rao, D.S.4
Yang, L.5
Baltimore, D.6
-
5
-
-
84863697528
-
Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape
-
K.J. Bar, C.Y. Tsao, S.S. Iyer, J.M. Decker, Y. Yang, M. Bonsignori, X. Chen, K.K. Hwang, D.C. Montefiori, and H.X. Liao et al. Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape PLoS Pathog. 8 2012 e1002721
-
(2012)
PLoS Pathog.
, vol.8
, pp. 1002721
-
-
Bar, K.J.1
Tsao, C.Y.2
Iyer, S.S.3
Decker, J.M.4
Yang, Y.5
Bonsignori, M.6
Chen, X.7
Hwang, K.K.8
Montefiori, D.C.9
Liao, H.X.10
-
6
-
-
84887626950
-
Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys
-
D.H. Barouch, J.B. Whitney, B. Moldt, F. Klein, T.Y. Oliveira, J. Liu, K.E. Stephenson, H.W. Chang, K. Shekhar, and S. Gupta et al. Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys Nature 503 2013 224 228
-
(2013)
Nature
, vol.503
, pp. 224-228
-
-
Barouch, D.H.1
Whitney, J.B.2
Moldt, B.3
Klein, F.4
Oliveira, T.Y.5
Liu, J.6
Stephenson, K.E.7
Chang, H.W.8
Shekhar, K.9
Gupta, S.10
-
7
-
-
84890196626
-
Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy
-
A. Bartesaghi, A. Merk, M.J. Borgnia, J.L. Milne, and S. Subramaniam Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy Nat. Struct. Mol. Biol. 20 2013 1352 1357
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 1352-1357
-
-
Bartesaghi, A.1
Merk, A.2
Borgnia, M.J.3
Milne, J.L.4
Subramaniam, S.5
-
8
-
-
0032100706
-
Affinity dependence of the B cell response to antigen: A threshold, a ceiling, and the importance of off-rate
-
DOI 10.1016/S1074-7613(00)80580-4
-
F.D. Batista, and M.S. Neuberger Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate Immunity 8 1998 751 759 (Pubitemid 28294522)
-
(1998)
Immunity
, vol.8
, Issue.6
, pp. 751-759
-
-
Batista, F.D.1
Neuberger, M.S.2
-
9
-
-
56449131391
-
Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C
-
J.M. Binley, E.A. Lybarger, E.T. Crooks, M.S. Seaman, E. Gray, K.L. Davis, J.M. Decker, D. Wycuff, L. Harris, and N. Hawkins et al. Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C J. Virol. 82 2008 11651 11668
-
(2008)
J. Virol.
, vol.82
, pp. 11651-11668
-
-
Binley, J.M.1
Lybarger, E.A.2
Crooks, E.T.3
Seaman, M.S.4
Gray, E.5
Davis, K.L.6
Decker, J.M.7
Wycuff, D.8
Harris, L.9
Hawkins, N.10
-
10
-
-
80052938385
-
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors
-
M. Bonsignori, K.K. Hwang, X. Chen, C.Y. Tsao, L. Morris, E. Gray, D.J. Marshall, J.A. Crump, S.H. Kapiga, and N.E. Sam et al. Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors J. Virol. 85 2011 9998 10009
-
(2011)
J. Virol.
, vol.85
, pp. 9998-10009
-
-
Bonsignori, M.1
Hwang, K.K.2
Chen, X.3
Tsao, C.Y.4
Morris, L.5
Gray, E.6
Marshall, D.J.7
Crump, J.A.8
Kapiga, S.H.9
Sam, N.E.10
-
11
-
-
0027985431
-
Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
-
D.R. Burton, J. Pyati, R. Koduri, S.J. Sharp, G.B. Thornton, P.W. Parren, L.S. Sawyer, R.M. Hendry, N. Dunlop, and P.L. Nara et al. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody Science 266 1994 1024 1027 (Pubitemid 24373715)
-
(1994)
Science
, vol.266
, Issue.5187
, pp. 1024-1027
-
-
Burton, D.R.1
Pyati, J.2
Koduri, R.3
Sharp, S.J.4
Thornton, G.B.5
Parren, P.W.H.I.6
Sawyer, L.S.W.7
Hendry, R.M.8
Dunlop, N.9
Nara, P.L.10
Lamacchia, M.11
Garratty, E.12
Stiehm, E.R.13
Bryson, Y.J.14
Cao, Y.15
Moore, J.P.16
Ho, D.D.17
Barbas III, C.F.18
-
12
-
-
84867630116
-
A Blueprint for HIV Vaccine Discovery
-
D.R. Burton, R. Ahmed, D.H. Barouch, S.T. Butera, S. Crotty, A. Godzik, D.E. Kaufmann, M.J. McElrath, M.C. Nussenzweig, and B. Pulendran et al. A Blueprint for HIV Vaccine Discovery Cell Host Microbe 12 2012 396 407
-
(2012)
Cell Host Microbe
, vol.12
, pp. 396-407
-
-
Burton, D.R.1
Ahmed, R.2
Barouch, D.H.3
Butera, S.T.4
Crotty, S.5
Godzik, A.6
Kaufmann, D.E.7
McElrath, M.J.8
Nussenzweig, M.C.9
Pulendran, B.10
-
13
-
-
12444291017
-
Antibody domain exchange is an immunological solution to carbohydrate cluster recognition
-
DOI 10.1126/science.1083182
-
D.A. Calarese, C.N. Scanlan, M.B. Zwick, S. Deechongkit, Y. Mimura, R. Kunert, P. Zhu, M.R. Wormald, R.L. Stanfield, and K.H. Roux et al. Antibody domain exchange is an immunological solution to carbohydrate cluster recognition Science 300 2003 2065 2071 (Pubitemid 36760127)
-
(2003)
Science
, vol.300
, Issue.5628
, pp. 2065-2071
-
-
Calarese, D.A.1
Scanlan, C.N.2
Zwick, M.B.3
Deechongkit, S.4
Mimura, Y.5
Kunert, R.6
Zhu, P.7
Wormald, M.R.8
Stanfield, R.L.9
Roux, K.H.10
Kelly, J.W.11
Rudd, P.M.12
Dwek, R.A.13
Katinger, H.14
Burton, D.R.15
Wilson, I.A.16
-
14
-
-
84880667257
-
Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10
-
Y. Chen, J. Zhang, K.K. Hwang, H. Bouton-Verville, S.M. Xia, A. Newman, Y.B. Ouyang, B.F. Haynes, and L. Verkoczy Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10 J. Immunol. 191 2013 1260 1275
-
(2013)
J. Immunol.
, vol.191
, pp. 1260-1275
-
-
Chen, Y.1
Zhang, J.2
Hwang, K.K.3
Bouton-Verville, H.4
Xia, S.M.5
Newman, A.6
Ouyang, Y.B.7
Haynes, B.F.8
Verkoczy, L.9
-
15
-
-
0036091692
-
Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU), is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virus
-
DOI 10.1128/JVI.76.11.5315-5325.2002
-
E. Chertova, J.W. Bess Jr., B.J. Crise, R.C. Sowder II, T.M. Schaden, J.M. Hilburn, J.A. Hoxie, R.E. Benveniste, J.D. Lifson, L.E. Henderson, and L.O. Arthur Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU), Is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virus J. Virol. 76 2002 5315 5325 (Pubitemid 34517882)
-
(2002)
Journal of Virology
, vol.76
, Issue.11
, pp. 5315-5325
-
-
Chertova, E.1
Bess Jr., J.W.2
Crise, B.J.3
Sowder II, R.C.4
Schaden, T.M.5
Hilburn, J.M.6
Hoxie, J.A.7
Benveniste, R.E.8
Lifson, J.D.9
Henderson, L.E.10
Arthur, L.O.11
-
16
-
-
84883381602
-
Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains
-
G.Y. Chuang, P. Acharya, S.D. Schmidt, Y. Yang, M.K. Louder, T. Zhou, Y.D. Kwon, M. Pancera, R.T. Bailer, and N.A. Doria-Rose et al. Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains J. Virol. 87 2013 10047 10058
-
(2013)
J. Virol.
, vol.87
, pp. 10047-10058
-
-
Chuang, G.Y.1
Acharya, P.2
Schmidt, S.D.3
Yang, Y.4
Louder, M.K.5
Zhou, T.6
Kwon, Y.D.7
Pancera, M.8
Bailer, R.T.9
Doria-Rose, N.A.10
-
18
-
-
0023176265
-
Antibody response to human immunodeficiency virus after primary infection
-
D.A. Cooper, A.A. Imrie, and R. Penny Antibody response to human immunodeficiency virus after primary infection J. Infect. Dis. 155 1987 1113 1118 (Pubitemid 17080483)
-
(1987)
Journal of Infectious Diseases
, vol.155
, Issue.6
, pp. 1113-1118
-
-
Cooper, D.A.1
Imrie, A.A.2
Penny, R.3
-
19
-
-
84861217014
-
HIV-1 superinfection in women broadens and strengthens the neutralizing antibody response
-
V. Cortez, K. Odem-Davis, R.S. McClelland, W. Jaoko, and J. Overbaugh HIV-1 superinfection in women broadens and strengthens the neutralizing antibody response PLoS Pathog. 8 2012 e1002611
-
(2012)
PLoS Pathog.
, vol.8
, pp. 1002611
-
-
Cortez, V.1
Odem-Davis, K.2
McClelland, R.S.3
Jaoko, W.4
Overbaugh, J.5
-
20
-
-
77649318846
-
Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals
-
D. Corti, J.P. Langedijk, A. Hinz, M.S. Seaman, F. Vanzetta, B.M. Fernandez-Rodriguez, C. Silacci, D. Pinna, D. Jarrossay, and S. Balla-Jhagjhoorsingh et al. Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals PLoS ONE 5 2010 e8805
-
(2010)
PLoS ONE
, vol.5
, pp. 8805
-
-
Corti, D.1
Langedijk, J.P.2
Hinz, A.3
Seaman, M.S.4
Vanzetta, F.5
Fernandez-Rodriguez, B.M.6
Silacci, C.7
Pinna, D.8
Jarrossay, D.9
Balla-Jhagjhoorsingh, S.10
-
21
-
-
80051670323
-
A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins
-
D. Corti, J. Voss, S.J. Gamblin, G. Codoni, A. Macagno, D. Jarrossay, S.G. Vachieri, D. Pinna, A. Minola, and F. Vanzetta et al. A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins Science 333 2011 850 856
-
(2011)
Science
, vol.333
, pp. 850-856
-
-
Corti, D.1
Voss, J.2
Gamblin, S.J.3
Codoni, G.4
Macagno, A.5
Jarrossay, D.6
Vachieri, S.G.7
Pinna, D.8
Minola, A.9
Vanzetta, F.10
-
22
-
-
0025735965
-
Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection
-
E.S. Daar, T. Moudgil, R.D. Meyer, and D.D. Ho Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection N. Engl. J. Med. 324 1991 961 964
-
(1991)
N. Engl. J. Med.
, vol.324
, pp. 961-964
-
-
Daar, E.S.1
Moudgil, T.2
Meyer, R.D.3
Ho, D.D.4
-
23
-
-
0027194963
-
Plasma viremia as a sensitive indicator of the antiretroviral activity of L-697,661
-
R.T. Davey Jr., R.L. Dewar, G.F. Reed, M.B. Vasudevachari, M.A. Polis, J.A. Kovacs, J. Falloon, R.E. Walker, H. Masur, and S.E. Haneiwich et al. Plasma viremia as a sensitive indicator of the antiretroviral activity of L-697,661 Proc. Natl. Acad. Sci. USA 90 1993 5608 5612 (Pubitemid 23176210)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.12
, pp. 5608-5612
-
-
Davey Jr., R.T.1
Dewar, R.L.2
Reed, G.F.3
Vasudevachari, M.B.4
Polis, M.A.5
Kovacs, J.A.6
Falloon, J.7
Walker, R.E.8
Masur, H.9
Haneiwich, S.E.10
O'Neill, D.G.11
Decker, M.R.12
Metcalf, J.A.13
Deloria, M.A.14
Laskin, O.L.15
Salzman, N.16
Lane, H.C.17
-
24
-
-
84856907465
-
Potent autologous and heterologous neutralizing antibody responses occur in HIV-2 infection across a broad range of infection outcomes
-
T.I. de Silva, M. Aasa-Chapman, M. Cotten, S. Hué, J. Robinson, F. Bibollet-Ruche, R. Sarge-Njie, N. Berry, A. Jaye, and P. Aaby et al. Potent autologous and heterologous neutralizing antibody responses occur in HIV-2 infection across a broad range of infection outcomes J. Virol. 86 2012 930 946
-
(2012)
J. Virol.
, vol.86
, pp. 930-946
-
-
De Silva, T.I.1
Aasa-Chapman, M.2
Cotten, M.3
Hué, S.4
Robinson, J.5
Bibollet-Ruche, F.6
Sarge-Njie, R.7
Berry, N.8
Jaye, A.9
Aaby, P.10
-
25
-
-
82755184131
-
Increasing the potency and breadth of an HIV antibody by using structure-based rational design
-
R. Diskin, J.F. Scheid, P.M. Marcovecchio, A.P. West Jr., F. Klein, H. Gao, P.N. Gnanapragasam, A. Abadir, M.S. Seaman, M.C. Nussenzweig, and P.J. Bjorkman Increasing the potency and breadth of an HIV antibody by using structure-based rational design Science 334 2011 1289 1293
-
(2011)
Science
, vol.334
, pp. 1289-1293
-
-
Diskin, R.1
Scheid, J.F.2
Marcovecchio, P.M.3
West Jr., A.P.4
Klein, F.5
Gao, H.6
Gnanapragasam, P.N.7
Abadir, A.8
Seaman, M.S.9
Nussenzweig, M.C.10
Bjorkman, P.J.11
-
26
-
-
84879523938
-
Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies
-
R. Diskin, F. Klein, J.A. Horwitz, A. Halper-Stromberg, D.N. Sather, P.M. Marcovecchio, T. Lee, A.P. West Jr., H. Gao, and M.S. Seaman et al. Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies J. Exp. Med. 210 2013 1235 1249
-
(2013)
J. Exp. Med.
, vol.210
, pp. 1235-1249
-
-
Diskin, R.1
Klein, F.2
Horwitz, J.A.3
Halper-Stromberg, A.4
Sather, D.N.5
Marcovecchio, P.M.6
Lee, T.7
West Jr., A.P.8
Gao, H.9
Seaman, M.S.10
-
27
-
-
58149399396
-
Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies
-
N.A. Doria-Rose, R.M. Klein, M.M. Manion, S. O'Dell, A. Phogat, B. Chakrabarti, C.W. Hallahan, S.A. Migueles, J. Wrammert, and R. Ahmed et al. Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies J. Virol. 83 2009 188 199
-
(2009)
J. Virol.
, vol.83
, pp. 188-199
-
-
Doria-Rose, N.A.1
Klein, R.M.2
Manion, M.M.3
O'Dell, S.4
Phogat, A.5
Chakrabarti, B.6
Hallahan, C.W.7
Migueles, S.A.8
Wrammert, J.9
Ahmed, R.10
-
28
-
-
73949084963
-
Breadth of human immunodeficiency virus-specific neutralizing activity in sera: Clustering analysis and association with clinical variables
-
N.A. Doria-Rose, R.M. Klein, M.G. Daniels, S. O'Dell, M. Nason, A. Lapedes, T. Bhattacharya, S.A. Migueles, R.T. Wyatt, and B.T. Korber et al. Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables J. Virol. 84 2010 1631 1636
-
(2010)
J. Virol.
, vol.84
, pp. 1631-1636
-
-
Doria-Rose, N.A.1
Klein, R.M.2
Daniels, M.G.3
O'Dell, S.4
Nason, M.5
Lapedes, A.6
Bhattacharya, T.7
Migueles, S.A.8
Wyatt, R.T.9
Korber, B.T.10
-
29
-
-
84899991983
-
Developmental pathway for potent V1V2-directed HIV-1-neutralizing antibodies
-
10.1038/nature13036 Published online March 2, 2014
-
N.A. Doria-Rose, C.A. Schramm, J. Gorman, P.L. Moore, J.N. Bhiman, R.P. Staupe, M.J. Ernandes, M. Pancera, H.R. Altae-Tran, and R.T. Bailer et al. Developmental pathway for potent V1V2-directed HIV-1-neutralizing antibodies Nature 2014 10.1038/nature13036 Published online March 2, 2014
-
(2014)
Nature
-
-
Doria-Rose, N.A.1
Schramm, C.A.2
Gorman, J.3
Moore, P.L.4
Bhiman, J.N.5
Staupe, R.P.6
Ernandes, M.J.7
Pancera, M.8
Altae-Tran, H.R.9
Bailer, R.T.10
-
30
-
-
84884215837
-
Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10
-
C. Doyle-Cooper, K.E. Hudson, A.B. Cooper, T. Ota, P. Skog, P.E. Dawson, M.B. Zwick, W.R. Schief, D.R. Burton, and D. Nemazee Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10 J. Immunol. 191 2013 3186 3191
-
(2013)
J. Immunol.
, vol.191
, pp. 3186-3191
-
-
Doyle-Cooper, C.1
Hudson, K.E.2
Cooper, A.B.3
Ota, T.4
Skog, P.5
Dawson, P.E.6
Zwick, M.B.7
Schief, W.R.8
Burton, D.R.9
Nemazee, D.10
-
31
-
-
84872817036
-
Genome-wide association study on the development of cross-reactive neutralizing antibodies in HIV-1 infected individuals
-
Z. Euler, M.J. van Gils, B.D. Boeser-Nunnink, H. Schuitemaker, and D. van Manen Genome-wide association study on the development of cross-reactive neutralizing antibodies in HIV-1 infected individuals PLoS ONE 8 2013 e54684
-
(2013)
PLoS ONE
, vol.8
, pp. 54684
-
-
Euler, Z.1
Van Gils, M.J.2
Boeser-Nunnink, B.D.3
Schuitemaker, H.4
Van Manen, D.5
-
32
-
-
84884698156
-
Autoreactivity and exceptional CDR plasticity (but not unusual polyspecificity) hinder elicitation of the anti-HIV antibody 4E10
-
K.A. Finton, K. Larimore, H.B. Larman, D. Friend, C. Correnti, P.B. Rupert, S.J. Elledge, P.D. Greenberg, and R.K. Strong Autoreactivity and exceptional CDR plasticity (but not unusual polyspecificity) hinder elicitation of the anti-HIV antibody 4E10 PLoS Pathog. 9 2013 e1003639
-
(2013)
PLoS Pathog.
, vol.9
, pp. 1003639
-
-
Finton, K.A.1
Larimore, K.2
Larman, H.B.3
Friend, D.4
Correnti, C.5
Rupert, P.B.6
Elledge, S.J.7
Greenberg, P.D.8
Strong, R.K.9
-
33
-
-
0025856601
-
Kinetic maturation of an immune response
-
J. Foote, and C. Milstein Kinetic maturation of an immune response Nature 352 1991 530 532 (Pubitemid 21912377)
-
(1991)
Nature
, vol.352
, Issue.6335
, pp. 530-532
-
-
Foote, J.1
Milstein, C.2
-
34
-
-
41649090223
-
A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies
-
DOI 10.1073/pnas.0800255105
-
G. Frey, H. Peng, S. Rits-Volloch, M. Morelli, Y. Cheng, and B. Chen A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies Proc. Natl. Acad. Sci. USA 105 2008 3739 3744 (Pubitemid 351723468)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.10
, pp. 3739-3744
-
-
Frey, G.1
Peng, H.2
Rits-Volloch, S.3
Morelli, M.4
Cheng, Y.5
Chen, B.6
-
35
-
-
0034094425
-
The RAG proteins and V(D)J recombination: Complexes, ends, and transposition
-
DOI 10.1146/annurev.immunol.18.1.495
-
S.D. Fugmann, A.I. Lee, P.E. Shockett, I.J. Villey, and D.G. Schatz The RAG proteins and V(D)J recombination: complexes, ends, and transposition Annu. Rev. Immunol. 18 2000 495 527 (Pubitemid 30365389)
-
(2000)
Annual Review of Immunology
, vol.18
, pp. 495-527
-
-
Fugmann, S.D.1
Lee, A.I.2
Shockett, P.E.3
Villey, I.J.4
Schatz, D.G.5
-
36
-
-
84865096278
-
Pathogenicity and mucosal transmissibility of the R5-tropic simian/human immunodeficiency virus SHIV(AD8) in rhesus macaques: Implications for use in vaccine studies
-
R. Gautam, Y. Nishimura, W.R. Lee, O. Donau, A. Buckler-White, M. Shingai, R. Sadjadpour, S.D. Schmidt, C.C. LaBranche, and B.F. Keele et al. Pathogenicity and mucosal transmissibility of the R5-tropic simian/human immunodeficiency virus SHIV(AD8) in rhesus macaques: implications for use in vaccine studies J. Virol. 86 2012 8516 8526
-
(2012)
J. Virol.
, vol.86
, pp. 8516-8526
-
-
Gautam, R.1
Nishimura, Y.2
Lee, W.R.3
Donau, O.4
Buckler-White, A.5
Shingai, M.6
Sadjadpour, R.7
Schmidt, S.D.8
Labranche, C.C.9
Keele, B.F.10
-
37
-
-
84877618448
-
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization
-
I.S. Georgiev, N.A. Doria-Rose, T. Zhou, Y.D. Kwon, R.P. Staupe, S. Moquin, G.Y. Chuang, M.K. Louder, S.D. Schmidt, and H.R. Altae-Tran et al. Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization Science 340 2013 751 756
-
(2013)
Science
, vol.340
, pp. 751-756
-
-
Georgiev, I.S.1
Doria-Rose, N.A.2
Zhou, T.3
Kwon, Y.D.4
Staupe, R.P.5
Moquin, S.6
Chuang, G.Y.7
Louder, M.K.8
Schmidt, S.D.9
Altae-Tran, H.R.10
-
38
-
-
84858389346
-
Outwitting evolution: Fighting drug-resistant TB, malaria, and HIV
-
D.E. Goldberg, R.F. Siliciano, and W.R. Jacobs Jr. Outwitting evolution: fighting drug-resistant TB, malaria, and HIV Cell 148 2012 1271 1283
-
(2012)
Cell
, vol.148
, pp. 1271-1283
-
-
Goldberg, D.E.1
Siliciano, R.F.2
Jacobs Jr., W.R.3
-
39
-
-
67449147145
-
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection
-
CHAVI Clinical Core B
-
N. Goonetilleke, M.K. Liu, J.F. Salazar-Gonzalez, G. Ferrari, E. Giorgi, V.V. Ganusov, B.F. Keele, G.H. Learn, E.L. Turnbull, M.G. Salazar CHAVI Clinical Core B The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection J. Exp. Med. 206 2009 1253 1272
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1253-1272
-
-
Goonetilleke, N.1
Liu, M.K.2
Salazar-Gonzalez, J.F.3
Ferrari, G.4
Giorgi, E.5
Ganusov, V.V.6
Keele, B.F.7
Learn, G.H.8
Turnbull, E.L.9
Salazar, M.G.10
-
40
-
-
0026486570
-
Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibody
-
M.K. Gorny, A.J. Conley, S. Karwowska, A. Buchbinder, J.Y. Xu, E.A. Emini, S. Koenig, and S. Zolla-Pazner Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibody J. Virol. 66 1992 7538 7542
-
(1992)
J. Virol.
, vol.66
, pp. 7538-7542
-
-
Gorny, M.K.1
Conley, A.J.2
Karwowska, S.3
Buchbinder, A.4
Xu, J.Y.5
Emini, E.A.6
Koenig, S.7
Zolla-Pazner, S.8
-
41
-
-
77954983245
-
Optimal antiretroviral therapy: HIV-1 treatment strategies to avoid and overcome drug resistance
-
P.M. Grant, and A.R. Zolopa Optimal antiretroviral therapy: HIV-1 treatment strategies to avoid and overcome drug resistance Curr. Opin. Investig. Drugs 11 2010 901 910
-
(2010)
Curr. Opin. Investig. Drugs
, vol.11
, pp. 901-910
-
-
Grant, P.M.1
Zolopa, A.R.2
-
42
-
-
34249940652
-
Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection
-
DOI 10.1128/JVI.00239-07
-
E.S. Gray, P.L. Moore, I.A. Choge, J.M. Decker, F. Bibollet-Ruche, H. Li, N. Leseka, F. Treurnicht, K. Mlisana, G.M. Shaw CAPRISA 002 Study Team Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection J. Virol. 81 2007 6187 6196 (Pubitemid 46878025)
-
(2007)
Journal of Virology
, vol.81
, Issue.12
, pp. 6187-6196
-
-
Gray, E.S.1
Moore, P.L.2
Choge, I.A.3
Decker, J.M.4
Bibollet-Ruche, F.5
Li, H.6
Leseka, N.7
Treurnicht, F.8
Mlisana, K.9
Shaw, G.M.10
Abdool Karim, S.S.11
Williamson, C.12
Morris, L.13
-
43
-
-
79955389756
-
The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection
-
CAPRISA002 Study Team
-
E.S. Gray, M.C. Madiga, T. Hermanus, P.L. Moore, C.K. Wibmer, N.L. Tumba, L. Werner, K. Mlisana, S. Sibeko, C. Williamson CAPRISA002 Study Team The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection J. Virol. 85 2011 4828 4840
-
(2011)
J. Virol.
, vol.85
, pp. 4828-4840
-
-
Gray, E.S.1
Madiga, M.C.2
Hermanus, T.3
Moore, P.L.4
Wibmer, C.K.5
Tumba, N.L.6
Werner, L.7
Mlisana, K.8
Sibeko, S.9
Williamson, C.10
-
44
-
-
84880683631
-
Antibody and antiretroviral preexposure prophylaxis prevent cervicovaginal HIV-1 infection in a transgenic mouse model
-
H. Gruell, S. Bournazos, J.V. Ravetch, A. Ploss, M.C. Nussenzweig, and J. Pietzsch Antibody and antiretroviral preexposure prophylaxis prevent cervicovaginal HIV-1 infection in a transgenic mouse model J. Virol. 87 2013 8535 8544
-
(2013)
J. Virol.
, vol.87
, pp. 8535-8544
-
-
Gruell, H.1
Bournazos, S.2
Ravetch, J.V.3
Ploss, A.4
Nussenzweig, M.C.5
Pietzsch, J.6
-
45
-
-
84865632697
-
Plasma HIV viral rebound following protocol-indicated cessation of ART commenced in primary and chronic HIV infection
-
INSIGHT SMART and SPARTAC Investigators
-
E. Hamlyn, F.M. Ewings, K. Porter, D.A. Cooper, G. Tambussi, M. Schechter, C. Pedersen, J.F. Okulicz, M. McClure, A. Babiker INSIGHT SMART and SPARTAC Investigators Plasma HIV viral rebound following protocol-indicated cessation of ART commenced in primary and chronic HIV infection PLoS ONE 7 2012 e43754
-
(2012)
PLoS ONE
, vol.7
, pp. 43754
-
-
Hamlyn, E.1
Ewings, F.M.2
Porter, K.3
Cooper, D.A.4
Tambussi, G.5
Schechter, M.6
Pedersen, C.7
Okulicz, J.F.8
McClure, M.9
Babiker, A.10
-
46
-
-
21344434534
-
Immunology: Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies
-
DOI 10.1126/science.1111781
-
B.F. Haynes, J. Fleming, E.W. St Clair, H. Katinger, G. Stiegler, R. Kunert, J. Robinson, R.M. Scearce, K. Plonk, and H.F. Staats et al. Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies Science 308 2005 1906 1908 (Pubitemid 40941873)
-
(2005)
Science
, vol.308
, Issue.5730
, pp. 1906-1908
-
-
Haynes, B.F.1
Fleming, J.2
St. Clair, E.W.3
Katinger, H.4
Stiegler, G.5
Kunert, R.6
Robinson, J.7
Scearce, R.M.8
Plonk, K.9
Staats, H.F.10
Ortel, T.L.11
Liao, H.-X.12
Alam, S.M.13
-
47
-
-
84860759632
-
B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study
-
B.F. Haynes, G. Kelsoe, S.C. Harrison, and T.B. Kepler B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study Nat. Biotechnol. 30 2012 423 433
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 423-433
-
-
Haynes, B.F.1
Kelsoe, G.2
Harrison, S.C.3
Kepler, T.B.4
-
48
-
-
84875061923
-
Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs
-
S. Hoot, A.T. McGuire, K.W. Cohen, R.K. Strong, L. Hangartner, F. Klein, R. Diskin, J.F. Scheid, D.N. Sather, D.R. Burton, and L. Stamatatos Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs PLoS Pathog. 9 2013 e1003106
-
(2013)
PLoS Pathog.
, vol.9
, pp. 1003106
-
-
Hoot, S.1
McGuire, A.T.2
Cohen, K.W.3
Strong, R.K.4
Hangartner, L.5
Klein, F.6
Diskin, R.7
Scheid, J.F.8
Sather, D.N.9
Burton, D.R.10
Stamatatos, L.11
-
49
-
-
84885338257
-
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice
-
J.A. Horwitz, A. Halper-Stromberg, H. Mouquet, A.D. Gitlin, A. Tretiakova, T.R. Eisenreich, M. Malbec, S. Gravemann, E. Billerbeck, and M. Dorner et al. HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice Proc. Natl. Acad. Sci. USA 110 2013 16538 16543
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 16538-16543
-
-
Horwitz, J.A.1
Halper-Stromberg, A.2
Mouquet, H.3
Gitlin, A.D.4
Tretiakova, A.5
Eisenreich, T.R.6
Malbec, M.7
Gravemann, S.8
Billerbeck, E.9
Dorner, M.10
-
50
-
-
0037227768
-
SF162P3 maps to envelope gp120
-
DOI 10.1128/JVI.77.2.989-998.2003
-
M. Hsu, J.M. Harouse, A. Gettie, C. Buckner, J. Blanchard, and C. Cheng-Mayer Increased mucosal transmission but not enhanced pathogenicity of the CCR5-tropic, simian AIDS-inducing simian/human immunodeficiency virus SHIV(SF162P3) maps to envelope gp120 J. Virol. 77 2003 989 998 (Pubitemid 36055521)
-
(2003)
Journal of Virology
, vol.77
, Issue.2
, pp. 989-998
-
-
Hsu, M.1
Harouse, J.M.2
Gettie, A.3
Buckner, C.4
Blanchard, J.5
Cheng-Mayer, C.6
-
51
-
-
84879107855
-
B-cell depletion reveals a role for antibodies in the control of chronic HIV-1 infection
-
K.H. Huang, D. Bonsall, A. Katzourakis, E.C. Thomson, S.J. Fidler, J. Main, D. Muir, J.N. Weber, A.J. Frater, and R.E. Phillips et al. B-cell depletion reveals a role for antibodies in the control of chronic HIV-1 infection Nat. Commun. 1 2010 102
-
(2010)
Nat. Commun.
, vol.1
, pp. 102
-
-
Huang, K.H.1
Bonsall, D.2
Katzourakis, A.3
Thomson, E.C.4
Fidler, S.J.5
Main, J.6
Muir, D.7
Weber, J.N.8
Frater, A.J.9
Phillips, R.E.10
-
52
-
-
84866493348
-
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
-
J. Huang, G. Ofek, L. Laub, M.K. Louder, N.A. Doria-Rose, N.S. Longo, H. Imamichi, R.T. Bailer, B. Chakrabarti, and S.K. Sharma et al. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody Nature 491 2012 406 412
-
(2012)
Nature
, vol.491
, pp. 406-412
-
-
Huang, J.1
Ofek, G.2
Laub, L.3
Louder, M.K.4
Doria-Rose, N.A.5
Longo, N.S.6
Imamichi, H.7
Bailer, R.T.8
Chakrabarti, B.9
Sharma, S.K.10
-
53
-
-
0032905728
-
Human immunodeficiency virus type 1 neutralizing antibodies accelerate clearance of cell-free virions from blood plasma
-
DOI 10.1038/5576
-
T. Igarashi, C. Brown, A. Azadegan, N. Haigwood, D. Dimitrov, M.A. Martin, and R. Shibata Human immunodeficiency virus type 1 neutralizing antibodies accelerate clearance of cell-free virions from blood plasma Nat. Med. 5 1999 211 216 (Pubitemid 29068529)
-
(1999)
Nature Medicine
, vol.5
, Issue.2
, pp. 211-216
-
-
Igarashi, T.1
Brown, C.2
Azadegan, A.3
Haigwood, N.4
Dimitrov, D.5
Martin, M.A.6
Shibata, R.7
-
54
-
-
84877609579
-
Rational HIV immunogen design to target specific germline B cell receptors
-
J. Jardine, J.P. Julien, S. Menis, T. Ota, O. Kalyuzhniy, A. McGuire, D. Sok, P.S. Huang, S. MacPherson, and M. Jones et al. Rational HIV immunogen design to target specific germline B cell receptors Science 340 2013 711 716
-
(2013)
Science
, vol.340
, pp. 711-716
-
-
Jardine, J.1
Julien, J.P.2
Menis, S.3
Ota, T.4
Kalyuzhniy, O.5
McGuire, A.6
Sok, D.7
Huang, P.S.8
MacPherson, S.9
Jones, M.10
-
55
-
-
0022558297
-
Replacing the complementary determining regions in a human antibody with those from a mouse
-
P.T. Jones, P.H. Dear, J. Foote, M.S. Neuberger, and G. Winter Replacing the complementarity-determining regions in a human antibody with those from a mouse Nature 321 1986 522 525 (Pubitemid 16052256)
-
(1986)
Nature
, vol.321
, Issue.6069
, pp. 522-525
-
-
Jones, P.T.1
Dear, P.H.2
Foote, J.3
-
56
-
-
84890858459
-
Crystal structure of a soluble cleaved HIV-1 envelope trimer
-
J.P. Julien, A. Cupo, D. Sok, R.L. Stanfield, D. Lyumkis, M.C. Deller, P.J. Klasse, D.R. Burton, R.W. Sanders, and J.P. Moore et al. Crystal structure of a soluble cleaved HIV-1 envelope trimer Science 342 2013 1477 1483
-
(2013)
Science
, vol.342
, pp. 1477-1483
-
-
Julien, J.P.1
Cupo, A.2
Sok, D.3
Stanfield, R.L.4
Lyumkis, D.5
Deller, M.C.6
Klasse, P.J.7
Burton, D.R.8
Sanders, R.W.9
Moore, J.P.10
-
57
-
-
84875034460
-
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9
-
J.P. Julien, J.H. Lee, A. Cupo, C.D. Murin, R. Derking, S. Hoffenberg, M.J. Caulfield, C.R. King, A.J. Marozsan, and P.J. Klasse et al. Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9 Proc. Natl. Acad. Sci. USA 110 2013 4351 4356
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 4351-4356
-
-
Julien, J.P.1
Lee, J.H.2
Cupo, A.3
Murin, C.D.4
Derking, R.5
Hoffenberg, S.6
Caulfield, M.J.7
King, C.R.8
Marozsan, A.J.9
Klasse, P.J.10
-
58
-
-
84878519611
-
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans
-
J.P. Julien, D. Sok, R. Khayat, J.H. Lee, K.J. Doores, L.M. Walker, A. Ramos, D.C. Diwanji, R. Pejchal, and A. Cupo et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans PLoS Pathog. 9 2013 e1003342
-
(2013)
PLoS Pathog.
, vol.9
, pp. 1003342
-
-
Julien, J.P.1
Sok, D.2
Khayat, R.3
Lee, J.H.4
Doores, K.J.5
Walker, L.M.6
Ramos, A.7
Diwanji, D.C.8
Pejchal, R.9
Cupo, A.10
-
59
-
-
33646181086
-
Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus
-
D. Jung, C. Giallourakis, R. Mostoslavsky, and F.W. Alt Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus Annu. Rev. Immunol. 24 2006 541 570
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 541-570
-
-
Jung, D.1
Giallourakis, C.2
Mostoslavsky, R.3
Alt, F.W.4
-
60
-
-
77954042425
-
Few and far between: How HIV may be evading antibody avidity
-
J.S. Klein, and P.J. Bjorkman Few and far between: how HIV may be evading antibody avidity PLoS Pathog. 6 2010 e1000908
-
(2010)
PLoS Pathog.
, vol.6
, pp. 1000908
-
-
Klein, J.S.1
Bjorkman, P.J.2
-
61
-
-
66149132686
-
Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10
-
J.S. Klein, P.N. Gnanapragasam, R.P. Galimidi, C.P. Foglesong, A.P. West Jr., and P.J. Bjorkman Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10 Proc. Natl. Acad. Sci. USA 106 2009 7385 7390
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 7385-7390
-
-
Klein, J.S.1
Gnanapragasam, P.N.2
Galimidi, R.P.3
Foglesong, C.P.4
West Jr., A.P.5
Bjorkman, P.J.6
-
62
-
-
84866443327
-
Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein
-
F. Klein, C. Gaebler, H. Mouquet, D.N. Sather, C. Lehmann, J.F. Scheid, Z. Kraft, Y. Liu, J. Pietzsch, and A. Hurley et al. Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein J. Exp. Med. 209 2012 1469 1479
-
(2012)
J. Exp. Med.
, vol.209
, pp. 1469-1479
-
-
Klein, F.1
Gaebler, C.2
Mouquet, H.3
Sather, D.N.4
Lehmann, C.5
Scheid, J.F.6
Kraft, Z.7
Liu, Y.8
Pietzsch, J.9
Hurley, A.10
-
63
-
-
84870562234
-
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
-
F. Klein, A. Halper-Stromberg, J.A. Horwitz, H. Gruell, J.F. Scheid, S. Bournazos, H. Mouquet, L.A. Spatz, R. Diskin, and A. Abadir et al. HIV therapy by a combination of broadly neutralizing antibodies in humanized mice Nature 492 2012 118 122
-
(2012)
Nature
, vol.492
, pp. 118-122
-
-
Klein, F.1
Halper-Stromberg, A.2
Horwitz, J.A.3
Gruell, H.4
Scheid, J.F.5
Bournazos, S.6
Mouquet, H.7
Spatz, L.A.8
Diskin, R.9
Abadir, A.10
-
64
-
-
84875759341
-
Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization
-
F. Klein, R. Diskin, J.F. Scheid, C. Gaebler, H. Mouquet, I.S. Georgiev, M. Pancera, T. Zhou, R.B. Incesu, and B.Z. Fu et al. Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization Cell 153 2013 126 138
-
(2013)
Cell
, vol.153
, pp. 126-138
-
-
Klein, F.1
Diskin, R.2
Scheid, J.F.3
Gaebler, C.4
Mouquet, H.5
Georgiev, I.S.6
Pancera, M.7
Zhou, T.8
Incesu, R.B.9
Fu, B.Z.10
-
65
-
-
84883796903
-
Antibodies in HIV-1 vaccine development and therapy
-
F. Klein, H. Mouquet, P. Dosenovic, J.F. Scheid, L. Scharf, and M.C. Nussenzweig Antibodies in HIV-1 vaccine development and therapy Science 341 2013 1199 1204
-
(2013)
Science
, vol.341
, pp. 1199-1204
-
-
Klein, F.1
Mouquet, H.2
Dosenovic, P.3
Scheid, J.F.4
Scharf, L.5
Nussenzweig, M.C.6
-
66
-
-
84869111491
-
Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies
-
R. Kong, H. Li, I. Georgiev, A. Changela, F. Bibollet-Ruche, J.M. Decker, S.L. Rowland-Jones, A. Jaye, Y. Guan, and G.K. Lewis et al. Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies J. Virol. 86 2012 12115 12128
-
(2012)
J. Virol.
, vol.86
, pp. 12115-12128
-
-
Kong, R.1
Li, H.2
Georgiev, I.3
Changela, A.4
Bibollet-Ruche, F.5
Decker, J.M.6
Rowland-Jones, S.L.7
Jaye, A.8
Guan, Y.9
Lewis, G.K.10
-
67
-
-
84880161438
-
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
-
L. Kong, J.H. Lee, K.J. Doores, C.D. Murin, J.P. Julien, R. McBride, Y. Liu, A. Marozsan, A. Cupo, and P.J. Klasse et al. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 Nat. Struct. Mol. Biol. 20 2013 796 803
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 796-803
-
-
Kong, L.1
Lee, J.H.2
Doores, K.J.3
Murin, C.D.4
Julien, J.P.5
McBride, R.6
Liu, Y.7
Marozsan, A.8
Cupo, A.9
Klasse, P.J.10
-
68
-
-
0028337166
-
Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
-
R.A. Koup, J.T. Safrit, Y. Cao, C.A. Andrews, G. McLeod, W. Borkowsky, C. Farthing, and D.D. Ho Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome J. Virol. 68 1994 4650 4655 (Pubitemid 24183063)
-
(1994)
Journal of Virology
, vol.68
, Issue.7
, pp. 4650-4655
-
-
Koup, R.A.1
Safrit, J.T.2
Cao, Y.3
Andrews, C.A.4
McLeod, G.5
Borkowsky, W.6
Farthing, C.7
Ho, D.D.8
-
69
-
-
38949206356
-
Passive immunization as tool to identify protective HIV-1 env epitopes
-
DOI 10.2174/157016207782418506
-
V.G. Kramer, N.B. Siddappa, and R.M. Ruprecht Passive immunization as tool to identify protective HIV-1 Env epitopes Curr. HIV Res. 5 2007 642 655 (Pubitemid 351210997)
-
(2007)
Current HIV Research
, vol.5
, Issue.6
, pp. 642-655
-
-
Kramer, V.G.1
Siddappa, N.B.2
Ruprecht, R.M.3
-
70
-
-
84866495323
-
Human antibodies that neutralize HIV-1: Identification, structures, and B cell ontogenies
-
P.D. Kwong, and J.R. Mascola Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies Immunity 37 2012 412 425
-
(2012)
Immunity
, vol.37
, pp. 412-425
-
-
Kwong, P.D.1
Mascola, J.R.2
-
71
-
-
0032543307
-
Structure of an HIV gp 120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
-
DOI 10.1038/31405
-
P.D. Kwong, R. Wyatt, J. Robinson, R.W. Sweet, J. Sodroski, and W.A. Hendrickson Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody Nature 393 1998 648 659 (Pubitemid 28289647)
-
(1998)
Nature
, vol.393
, Issue.6686
, pp. 648-659
-
-
Kwong, P.D.1
Wyatt, R.2
Robinson, J.3
Sweet, R.W.4
Sodroski, J.5
Hendrickson, W.A.6
-
72
-
-
0037069682
-
HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites
-
DOI 10.1038/nature01188
-
P.D. Kwong, M.L. Doyle, D.J. Casper, C. Cicala, S.A. Leavitt, S. Majeed, T.D. Steenbeke, M. Venturi, I. Chaiken, and M. Fung et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites Nature 420 2002 678 682 (Pubitemid 36764500)
-
(2002)
Nature
, vol.420
, Issue.6916
, pp. 678-682
-
-
Kwong, P.D.1
Doyle, M.L.2
Casper, D.J.3
Cicala, C.4
Leavitt, S.A.5
Majeed, S.6
Steenbeke, T.D.7
Venturi, M.8
Chaiken, I.9
Fung, M.10
Katinger, H.11
Parren, P.W.I.H.12
Robinson, J.13
Van Ryk, D.14
Wang, L.15
Burton, D.R.16
Freire, E.17
Wyatt, R.18
Sodroski, J.19
Hendrickson, W.A.20
Arthos, J.21
more..
-
73
-
-
84883187027
-
Broadly neutralizing antibodies and the search for an HIV-1 vaccine: The end of the beginning
-
P.D. Kwong, J.R. Mascola, and G.J. Nabel Broadly neutralizing antibodies and the search for an HIV-1 vaccine: the end of the beginning Nat. Rev. Immunol. 13 2013 693 701
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 693-701
-
-
Kwong, P.D.1
Mascola, J.R.2
Nabel, G.J.3
-
74
-
-
79958033481
-
IMGT unique numbering for the variable (V), constant (C), and groove (G) domains of IG, TR, MH, IgSF, and MhSF
-
M.P. Lefranc IMGT unique numbering for the variable (V), constant (C), and groove (G) domains of IG, TR, MH, IgSF, and MhSF Cold Spring Harb Protoc 2011 2011 633 642
-
(2011)
Cold Spring Harb Protoc
, vol.2011
, pp. 633-642
-
-
Lefranc, M.P.1
-
75
-
-
34948854718
-
Broad HIV-1 neutralization mediated by CD4-binding site antibodies
-
DOI 10.1038/nm1624, PII NM1624
-
Y. Li, S.A. Migueles, B. Welcher, K. Svehla, A. Phogat, M.K. Louder, X. Wu, G.M. Shaw, M. Connors, R.T. Wyatt, and J.R. Mascola Broad HIV-1 neutralization mediated by CD4-binding site antibodies Nat. Med. 13 2007 1032 1034 (Pubitemid 47517505)
-
(2007)
Nature Medicine
, vol.13
, Issue.9
, pp. 1032-1034
-
-
Li, Y.1
Migueles, S.A.2
Welcher, B.3
Svehla, K.4
Phogat, A.5
Louder, M.K.6
Wu, X.7
Shaw, G.M.8
Connors, M.9
Wyatt, R.T.10
Mascola, J.R.11
-
76
-
-
84876797103
-
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
-
NISC Comparative Sequencing Program
-
H.X. Liao, R. Lynch, T. Zhou, F. Gao, S.M. Alam, S.D. Boyd, A.Z. Fire, K.M. Roskin, C.A. Schramm, Z. Zhang NISC Comparative Sequencing Program Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus Nature 496 2013 469 476
-
(2013)
Nature
, vol.496
, pp. 469-476
-
-
Liao, H.X.1
Lynch, R.2
Zhou, T.3
Gao, F.4
Alam, S.M.5
Boyd, S.D.6
Fire, A.Z.7
Roskin, K.M.8
Schramm, C.A.9
Zhang, Z.10
-
77
-
-
51349162563
-
Molecular architecture of native HIV-1 gp120 trimers
-
J. Liu, A. Bartesaghi, M.J. Borgnia, G. Sapiro, and S. Subramaniam Molecular architecture of native HIV-1 gp120 trimers Nature 455 2008 109 113
-
(2008)
Nature
, vol.455
, pp. 109-113
-
-
Liu, J.1
Bartesaghi, A.2
Borgnia, M.J.3
Sapiro, G.4
Subramaniam, S.5
-
78
-
-
84878566279
-
Inhibition of the HIV-1 spike by single-PG9/16-antibody binding suggests a coordinated-activation model for its three protomeric units
-
R. Löving, M. Sjöberg, S.R. Wu, J.M. Binley, and H. Garoff Inhibition of the HIV-1 spike by single-PG9/16-antibody binding suggests a coordinated-activation model for its three protomeric units J. Virol. 87 2013 7000 7007
-
(2013)
J. Virol.
, vol.87
, pp. 7000-7007
-
-
Löving, R.1
Sjöberg, M.2
Wu, S.R.3
Binley, J.M.4
Garoff, H.5
-
79
-
-
84890859441
-
Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer
-
D. Lyumkis, J.P. Julien, N. de Val, A. Cupo, C.S. Potter, P.J. Klasse, D.R. Burton, R.W. Sanders, J.P. Moore, and B. Carragher et al. Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer Science 342 2013 1484 1490
-
(2013)
Science
, vol.342
, pp. 1484-1490
-
-
Lyumkis, D.1
Julien, J.P.2
De Val, N.3
Cupo, A.4
Potter, C.S.5
Klasse, P.J.6
Burton, D.R.7
Sanders, R.W.8
Moore, J.P.9
Carragher, B.10
-
80
-
-
84890824652
-
Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission
-
M. Malbec, F. Porrot, R. Rua, J. Horwitz, F. Klein, A. Halper-Stromberg, J.F. Scheid, C. Eden, H. Mouquet, M.C. Nussenzweig, and O. Schwartz Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission J. Exp. Med. 210 2013 2813 2821
-
(2013)
J. Exp. Med.
, vol.210
, pp. 2813-2821
-
-
Malbec, M.1
Porrot, F.2
Rua, R.3
Horwitz, J.4
Klein, F.5
Halper-Stromberg, A.6
Scheid, J.F.7
Eden, C.8
Mouquet, H.9
Nussenzweig, M.C.10
Schwartz, O.11
-
82
-
-
84874561170
-
Neutralizing antibodies to HIV-1 induced by immunization
-
L.E. McCoy, and R.A. Weiss Neutralizing antibodies to HIV-1 induced by immunization J. Exp. Med. 210 2013 209 223
-
(2013)
J. Exp. Med.
, vol.210
, pp. 209-223
-
-
McCoy, L.E.1
Weiss, R.A.2
-
83
-
-
84878626061
-
Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies
-
A.T. McGuire, S. Hoot, A.M. Dreyer, A. Lippy, A. Stuart, K.W. Cohen, J. Jardine, S. Menis, J.F. Scheid, and A.P. West et al. Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies J. Exp. Med. 210 2013 655 663
-
(2013)
J. Exp. Med.
, vol.210
, pp. 655-663
-
-
McGuire, A.T.1
Hoot, S.2
Dreyer, A.M.3
Lippy, A.4
Stuart, A.5
Cohen, K.W.6
Jardine, J.7
Menis, S.8
Scheid, J.F.9
West, A.P.10
-
84
-
-
83455254775
-
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
-
J.S. McLellan, M. Pancera, C. Carrico, J. Gorman, J.P. Julien, R. Khayat, R. Louder, R. Pejchal, M. Sastry, and K. Dai et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 Nature 480 2011 336 343
-
(2011)
Nature
, vol.480
, pp. 336-343
-
-
McLellan, J.S.1
Pancera, M.2
Carrico, C.3
Gorman, J.4
Julien, J.P.5
Khayat, R.6
Louder, R.7
Pejchal, R.8
Sastry, M.9
Dai, K.10
-
85
-
-
72949117233
-
The immune response during acute HIV-1 infection: Clues for vaccine development
-
A.J. McMichael, P. Borrow, G.D. Tomaras, N. Goonetilleke, and B.F. Haynes The immune response during acute HIV-1 infection: clues for vaccine development Nat. Rev. Immunol. 10 2010 11 23
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 11-23
-
-
McMichael, A.J.1
Borrow, P.2
Tomaras, G.D.3
Goonetilleke, N.4
Haynes, B.F.5
-
86
-
-
0034823216
-
Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development
-
DOI 10.1172/JCI200113051
-
E. Meffre, M. Milili, C. Blanco-Betancourt, H. Antunes, M.C. Nussenzweig, and C. Schiff Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development J. Clin. Invest. 108 2001 879 886 (Pubitemid 32884193)
-
(2001)
Journal of Clinical Investigation
, vol.108
, Issue.6
, pp. 879-886
-
-
Meffre, E.1
Milili, M.2
Blanco-Betancourt, C.3
Antunes, H.4
Nussenzweig, M.C.5
Schiff, C.6
-
87
-
-
35148864699
-
Adjunctive passive immunotherapy in human immunodeficiency virus type 1-infected individuals treated with antiviral therapy during acute and early infection
-
DOI 10.1128/JVI.01340-07
-
S. Mehandru, B. Vcelar, T. Wrin, G. Stiegler, B. Joos, H. Mohri, D. Boden, J. Galovich, K. Tenner-Racz, and P. Racz et al. Adjunctive passive immunotherapy in human immunodeficiency virus type 1-infected individuals treated with antiviral therapy during acute and early infection J. Virol. 81 2007 11016 11031 (Pubitemid 47536075)
-
(2007)
Journal of Virology
, vol.81
, Issue.20
, pp. 11016-11031
-
-
Mehandru, S.1
Vcelar, B.2
Wrin, T.3
Stiegler, G.4
Joos, B.5
Mohri, H.6
Boden, D.7
Galovich, J.8
Tenner-Racz, K.9
Racz, P.10
Carrington, M.11
Petropoulos, C.12
Katinger, H.13
Markowitz, M.14
-
88
-
-
0034646143
-
HLA B 5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors
-
DOI 10.1073/pnas.050567397
-
-5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors Proc. Natl. Acad. Sci. USA 97 2000 2709 2714 (Pubitemid 30159236)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.6
, pp. 2709-2714
-
-
Migueles, S.A.1
Sabbaghian, M.S.2
Shupert, W.L.3
Bettinotti, M.P.4
Marincola, F.M.5
Martino, L.6
Hallahan, C.W.7
Selig, S.M.8
Schwartz, D.9
Sullivan, J.10
Connors, M.11
-
89
-
-
79551518897
-
Characteristics of the earliest cross-neutralizing antibody response to HIV-1
-
I. Mikell, D.N. Sather, S.A. Kalams, M. Altfeld, G. Alter, and L. Stamatatos Characteristics of the earliest cross-neutralizing antibody response to HIV-1 PLoS Pathog. 7 2011 e1001251
-
(2011)
PLoS Pathog.
, vol.7
, pp. 1001251
-
-
Mikell, I.1
Sather, D.N.2
Kalams, S.A.3
Altfeld, M.4
Alter, G.5
Stamatatos, L.6
-
90
-
-
84869155712
-
Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape
-
P.L. Moore, E.S. Gray, C.K. Wibmer, J.N. Bhiman, M. Nonyane, D.J. Sheward, T. Hermanus, S. Bajimaya, N.L. Tumba, and M.R. Abrahams et al. Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape Nat. Med. 18 2012 1688 1692
-
(2012)
Nat. Med.
, vol.18
, pp. 1688-1692
-
-
Moore, P.L.1
Gray, E.S.2
Wibmer, C.K.3
Bhiman, J.N.4
Nonyane, M.5
Sheward, D.J.6
Hermanus, T.7
Bajimaya, S.8
Tumba, N.L.9
Abrahams, M.R.10
-
91
-
-
84862314634
-
Polyreactive antibodies in adaptive immune responses to viruses
-
H. Mouquet, and M.C. Nussenzweig Polyreactive antibodies in adaptive immune responses to viruses Cell. Mol. Life Sci. 69 2012 1435 1445
-
(2012)
Cell. Mol. Life Sci.
, vol.69
, pp. 1435-1445
-
-
Mouquet, H.1
Nussenzweig, M.C.2
-
92
-
-
77957355961
-
Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
-
H. Mouquet, J.F. Scheid, M.J. Zoller, M. Krogsgaard, R.G. Ott, S. Shukair, M.N. Artyomov, J. Pietzsch, M. Connors, and F. Pereyra et al. Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation Nature 467 2010 591 595
-
(2010)
Nature
, vol.467
, pp. 591-595
-
-
Mouquet, H.1
Scheid, J.F.2
Zoller, M.J.3
Krogsgaard, M.4
Ott, R.G.5
Shukair, S.6
Artyomov, M.N.7
Pietzsch, J.8
Connors, M.9
Pereyra, F.10
-
93
-
-
84869831194
-
Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
-
H. Mouquet, L. Scharf, Z. Euler, Y. Liu, C. Eden, J.F. Scheid, A. Halper-Stromberg, P.N. Gnanapragasam, D.I. Spencer, and M.S. Seaman et al. Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies Proc. Natl. Acad. Sci. USA 109 2012 E3268 E3277
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
-
-
Mouquet, H.1
Scharf, L.2
Euler, Z.3
Liu, Y.4
Eden, C.5
Scheid, J.F.6
Halper-Stromberg, A.7
Gnanapragasam, P.N.8
Spencer, D.I.9
Seaman, M.S.10
-
94
-
-
84856371864
-
Enhanced HIV-1 neutralization by antibody heteroligation
-
H. Mouquet, M. Warncke, J.F. Scheid, M.S. Seaman, and M.C. Nussenzweig Enhanced HIV-1 neutralization by antibody heteroligation Proc. Natl. Acad. Sci. USA 109 2012 875 880
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 875-880
-
-
Mouquet, H.1
Warncke, M.2
Scheid, J.F.3
Seaman, M.S.4
Nussenzweig, M.C.5
-
95
-
-
0027378573
-
A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
-
T. Muster, F. Steindl, M. Purtscher, A. Trkola, A. Klima, G. Himmler, F. Rüker, and H. Katinger A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1 J. Virol. 67 1993 6642 6647 (Pubitemid 23309131)
-
(1993)
Journal of Virology
, vol.67
, Issue.11
, pp. 6642-6647
-
-
Muster, T.1
Steindl, F.2
Purtscher, M.3
Trkola, A.4
Klima, A.5
Himmler, G.6
Ruker, F.7
Katinger, H.8
-
96
-
-
34247106331
-
An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10
-
DOI 10.1128/JVI.02588-06
-
J.D. Nelson, F.M. Brunel, R. Jensen, E.T. Crooks, R.M. Cardoso, M. Wang, A. Hessell, I.A. Wilson, J.M. Binley, and P.E. Dawson et al. An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10 J. Virol. 81 2007 4033 4043 (Pubitemid 46586898)
-
(2007)
Journal of Virology
, vol.81
, Issue.8
, pp. 4033-4043
-
-
Nelson, J.D.1
Brunel, F.M.2
Jensen, R.3
Crooks, E.T.4
Cardoso, R.M.F.5
Wang, M.6
Hessell, A.7
Wilson, I.A.8
Binley, J.M.9
Dawson, P.E.10
Burton, D.R.11
Zwick, M.B.12
-
97
-
-
37549036732
-
Fcgamma receptors as regulators of immune responses
-
F. Nimmerjahn, and J.V. Ravetch Fcgamma receptors as regulators of immune responses Nat. Rev. Immunol. 8 2008 34 47
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 34-47
-
-
Nimmerjahn, F.1
Ravetch, J.V.2
-
98
-
-
77649132440
-
Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region
-
G. Ofek, K. McKee, Y. Yang, Z.Y. Yang, J. Skinner, F.J. Guenaga, R. Wyatt, M.B. Zwick, G.J. Nabel, J.R. Mascola, and P.D. Kwong Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region J. Virol. 84 2010 2955 2962
-
(2010)
J. Virol.
, vol.84
, pp. 2955-2962
-
-
Ofek, G.1
McKee, K.2
Yang, Y.3
Yang, Z.Y.4
Skinner, J.5
Guenaga, F.J.6
Wyatt, R.7
Zwick, M.B.8
Nabel, G.J.9
Mascola, J.R.10
Kwong, P.D.11
-
100
-
-
84856890445
-
Potent intratype neutralizing activity distinguishes human immunodeficiency virus type 2 (HIV-2) from HIV-1
-
G. Ozkaya Sahin, B. Holmgren, Z. da Silva, J. Nielsen, S. Nowroozalizadeh, J. Esbjörnsson, F. Månsson, S. Andersson, H. Norrgren, and P. Aaby et al. Potent intratype neutralizing activity distinguishes human immunodeficiency virus type 2 (HIV-2) from HIV-1 J. Virol. 86 2012 961 971
-
(2012)
J. Virol.
, vol.86
, pp. 961-971
-
-
Ozkaya Sahin, G.1
Holmgren, B.2
Da Silva, Z.3
Nielsen, J.4
Nowroozalizadeh, S.5
Esbjörnsson, J.6
Månsson, F.7
Andersson, S.8
Norrgren, H.9
Aaby, P.10
-
101
-
-
84880149399
-
Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16
-
M. Pancera, S. Shahzad-Ul-Hussan, N.A. Doria-Rose, J.S. McLellan, R.T. Bailer, K. Dai, S. Loesgen, M.K. Louder, R.P. Staupe, and Y. Yang et al. Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16 Nat. Struct. Mol. Biol. 20 2013 804 813
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 804-813
-
-
Pancera, M.1
Shahzad-Ul-Hussan, S.2
Doria-Rose, N.A.3
McLellan, J.S.4
Bailer, R.T.5
Dai, K.6
Loesgen, S.7
Louder, M.K.8
Staupe, R.P.9
Yang, Y.10
-
102
-
-
84874203056
-
N332-Directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: Inferences from heavy-light chain complementation of function
-
M. Pancera, Y. Yang, M.K. Louder, J. Gorman, G. Lu, J.S. McLellan, J. Stuckey, J. Zhu, D.R. Burton, and W.C. Koff et al. N332-Directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function PLoS ONE 8 2013 e55701
-
(2013)
PLoS ONE
, vol.8
, pp. 55701
-
-
Pancera, M.1
Yang, Y.2
Louder, M.K.3
Gorman, J.4
Lu, G.5
McLellan, J.S.6
Stuckey, J.7
Zhu, J.8
Burton, D.R.9
Koff, W.C.10
-
103
-
-
82255179322
-
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield
-
R. Pejchal, K.J. Doores, L.M. Walker, R. Khayat, P.S. Huang, S.K. Wang, R.L. Stanfield, J.P. Julien, A. Ramos, and M. Crispin et al. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield Science 334 2011 1097 1103
-
(2011)
Science
, vol.334
, pp. 1097-1103
-
-
Pejchal, R.1
Doores, K.J.2
Walker, L.M.3
Khayat, R.4
Huang, P.S.5
Wang, S.K.6
Stanfield, R.L.7
Julien, J.P.8
Ramos, A.9
Crispin, M.10
-
104
-
-
77956237048
-
Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness
-
J. Pietzsch, J.F. Scheid, H. Mouquet, F. Klein, M.S. Seaman, M. Jankovic, D. Corti, A. Lanzavecchia, and M.C. Nussenzweig Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness J. Exp. Med. 207 2010 1995 2002
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1995-2002
-
-
Pietzsch, J.1
Scheid, J.F.2
Mouquet, H.3
Klein, F.4
Seaman, M.S.5
Jankovic, M.6
Corti, D.7
Lanzavecchia, A.8
Nussenzweig, M.C.9
-
105
-
-
0033119374
-
Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo
-
DOI 10.1016/S1074-7613(00)80043-6
-
P. Poignard, R. Sabbe, G.R. Picchio, M. Wang, R.J. Gulizia, H. Katinger, P.W. Parren, D.E. Mosier, and D.R. Burton Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo Immunity 10 1999 431 438 (Pubitemid 29205479)
-
(1999)
Immunity
, vol.10
, Issue.4
, pp. 431-438
-
-
Poignard, P.1
Sabbe, R.2
Picchio, G.R.3
Wang, M.4
Gulizia, R.J.5
Katinger, H.6
Parren, P.W.H.I.7
Mosier, D.E.8
Burton, D.R.9
-
106
-
-
77956048307
-
Infection by discordant strains of HIV-1 markedly enhances the neutralizing antibody response against heterologous virus
-
R.L. Powell, T. Kinge, and P.N. Nyambi Infection by discordant strains of HIV-1 markedly enhances the neutralizing antibody response against heterologous virus J. Virol. 84 2010 9415 9426
-
(2010)
J. Virol.
, vol.84
, pp. 9415-9426
-
-
Powell, R.L.1
Kinge, T.2
Nyambi, P.N.3
-
107
-
-
0026332977
-
Prevention of HIV infection by passive immunization with HIV immunoglobulin
-
A.M. Prince, H. Reesink, D. Pascual, B. Horowitz, I. Hewlett, K.K. Murthy, K.E. Cobb, and J.W. Eichberg Prevention of HIV infection by passive immunization with HIV immunoglobulin AIDS Res. Hum. Retroviruses 7 1991 971 973
-
(1991)
AIDS Res. Hum. Retroviruses
, vol.7
, pp. 971-973
-
-
Prince, A.M.1
Reesink, H.2
Pascual, D.3
Horowitz, B.4
Hewlett, I.5
Murthy, K.K.6
Cobb, K.E.7
Eichberg, J.W.8
-
108
-
-
0028794835
-
Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process
-
C.A. Reynaud, C. Garcia, W.R. Hein, and J.C. Weill Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process Cell 80 1995 115 125
-
(1995)
Cell
, vol.80
, pp. 115-125
-
-
Reynaud, C.A.1
Garcia, C.2
Hein, W.R.3
Weill, J.C.4
-
109
-
-
0027957791
-
Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy
-
D.D. Richman, D. Havlir, J. Corbeil, D. Looney, C. Ignacio, S.A. Spector, J. Sullivan, S. Cheeseman, K. Barringer, and D. Pauletti et al. Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy J. Virol. 68 1994 1660 1666 (Pubitemid 24065732)
-
(1994)
Journal of Virology
, vol.68
, Issue.3
, pp. 1660-1666
-
-
Richman, D.D.1
Havlir, D.2
Corbeil, J.3
Looney, D.4
Ignacio, C.5
Spector, S.A.6
Sullivan, J.7
Cheeseman, S.8
Barringer, K.9
Pauletti, D.10
Shih, C.-K.11
Myers, M.12
Griffin, J.13
-
110
-
-
0027537122
-
Hu-PBL-SCID mice can be protected from HIV-1 infection by passive transfer of monoclonal antibody to the principal neutralizing determinant of envelope gp120
-
J.T. Safrit, M.S. Fung, C.A. Andrews, D.G. Braun, W.N. Sun, T.W. Chang, and R.A. Koup hu-PBL-SCID mice can be protected from HIV-1 infection by passive transfer of monoclonal antibody to the principal neutralizing determinant of envelope gp120 AIDS 7 1993 15 21 (Pubitemid 23069026)
-
(1993)
AIDS
, vol.7
, Issue.1
, pp. 15-21
-
-
Safrit, J.T.1
Fung, M.S.C.2
Andrews, C.A.3
Braun, D.G.4
Sun, W.N.C.5
Chang, T.W.6
Koup, R.A.7
-
111
-
-
33748925430
-
Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity
-
DOI 10.1128/JVI.00141-06
-
M. Sagar, X. Wu, S. Lee, and J. Overbaugh Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity J. Virol. 80 2006 9586 9598 (Pubitemid 44435633)
-
(2006)
Journal of Virology
, vol.80
, Issue.19
, pp. 9586-9598
-
-
Sagar, M.1
Wu, X.2
Lee, S.3
Overbaugh, J.4
-
112
-
-
84884678235
-
A next-generation cleaved, soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies
-
R.W. Sanders, R. Derking, A. Cupo, J.P. Julien, A. Yasmeen, N. de Val, H.J. Kim, C. Blattner, A.T. de la Peña, and J. Korzun et al. A next-generation cleaved, soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies PLoS Pathog. 9 2013 e1003618
-
(2013)
PLoS Pathog.
, vol.9
, pp. 1003618
-
-
Sanders, R.W.1
Derking, R.2
Cupo, A.3
Julien, J.P.4
Yasmeen, A.5
De Val, N.6
Kim, H.J.7
Blattner, C.8
De La Peña, A.T.9
Korzun, J.10
-
113
-
-
58149487645
-
Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection
-
D.N. Sather, J. Armann, L.K. Ching, A. Mavrantoni, G. Sellhorn, Z. Caldwell, X. Yu, B. Wood, S. Self, S. Kalams, and L. Stamatatos Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection J. Virol. 83 2009 757 769
-
(2009)
J. Virol.
, vol.83
, pp. 757-769
-
-
Sather, D.N.1
Armann, J.2
Ching, L.K.3
Mavrantoni, A.4
Sellhorn, G.5
Caldwell, Z.6
Yu, X.7
Wood, B.8
Self, S.9
Kalams, S.10
Stamatatos, L.11
-
114
-
-
84869204900
-
Broadly neutralizing antibodies developed by an HIV-positive elite neutralizer exact a replication fitness cost on the contemporaneous virus
-
D.N. Sather, S. Carbonetti, J. Kehayia, Z. Kraft, I. Mikell, J.F. Scheid, F. Klein, and L. Stamatatos Broadly neutralizing antibodies developed by an HIV-positive elite neutralizer exact a replication fitness cost on the contemporaneous virus J. Virol. 86 2012 12676 12685
-
(2012)
J. Virol.
, vol.86
, pp. 12676-12685
-
-
Sather, D.N.1
Carbonetti, S.2
Kehayia, J.3
Kraft, Z.4
Mikell, I.5
Scheid, J.F.6
Klein, F.7
Stamatatos, L.8
-
115
-
-
78649339280
-
New templates for HIV-1 antibody-based vaccine design
-
Q.J. Sattentau, and A.J. McMichael New templates for HIV-1 antibody-based vaccine design F1000 Biol. Rep. 2 2010 60
-
(2010)
F1000 Biol. Rep.
, vol.2
, pp. 60
-
-
Sattentau, Q.J.1
McMichael, A.J.2
-
116
-
-
0028801450
-
Epitope exposure on functional, oligomeric HIV-1 gp41 molecules
-
Q.J. Sattentau, S. Zolla-Pazner, and P. Poignard Epitope exposure on functional, oligomeric HIV-1 gp41 molecules Virology 206 1995 713 717
-
(1995)
Virology
, vol.206
, pp. 713-717
-
-
Sattentau, Q.J.1
Zolla-Pazner, S.2
Poignard, P.3
-
117
-
-
18244422922
-
The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1 - >2 mannose residues on the outer face of gp120
-
C.N. Scanlan, R. Pantophlet, M.R. Wormald, E. Ollmann Saphire, R. Stanfield, I.A. Wilson, H. Katinger, R.A. Dwek, P.M. Rudd, and D.R. Burton The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1 - >2 mannose residues on the outer face of gp120 J. Virol. 76 2002 7306 7321
-
(2002)
J. Virol.
, vol.76
, pp. 7306-7321
-
-
Scanlan, C.N.1
Pantophlet, R.2
Wormald, M.R.3
Ollmann Saphire, E.4
Stanfield, R.5
Wilson, I.A.6
Katinger, H.7
Dwek, R.A.8
Rudd, P.M.9
Burton, D.R.10
-
118
-
-
63849131879
-
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
-
J.F. Scheid, H. Mouquet, N. Feldhahn, M.S. Seaman, K. Velinzon, J. Pietzsch, R.G. Ott, R.M. Anthony, H. Zebroski, and A. Hurley et al. Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals Nature 458 2009 636 640
-
(2009)
Nature
, vol.458
, pp. 636-640
-
-
Scheid, J.F.1
Mouquet, H.2
Feldhahn, N.3
Seaman, M.S.4
Velinzon, K.5
Pietzsch, J.6
Ott, R.G.7
Anthony, R.M.8
Zebroski, H.9
Hurley, A.10
-
119
-
-
80052925616
-
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding
-
J.F. Scheid, H. Mouquet, B. Ueberheide, R. Diskin, F. Klein, T.Y. Oliveira, J. Pietzsch, D. Fenyo, A. Abadir, and K. Velinzon et al. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding Science 333 2011 1633 1637
-
(2011)
Science
, vol.333
, pp. 1633-1637
-
-
Scheid, J.F.1
Mouquet, H.2
Ueberheide, B.3
Diskin, R.4
Klein, F.5
Oliveira, T.Y.6
Pietzsch, J.7
Fenyo, D.8
Abadir, A.9
Velinzon, K.10
-
120
-
-
0025133520
-
Human monoclonal antibody that recognizes the V3 region of human immunodeficiency virus gp120 and neutralizes the human T-lymphotropic virus type IIIMN strain
-
C.F. Scott Jr., S. Silver, A.T. Profy, S.D. Putney, A. Langlois, K. Weinhold, and J.E. Robinson Human monoclonal antibody that recognizes the V3 region of human immunodeficiency virus gp120 and neutralizes the human T-lymphotropic virus type IIIMN strain Proc. Natl. Acad. Sci. USA 87 1990 8597 8601
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 8597-8601
-
-
Scott Jr., C.F.1
Silver, S.2
Profy, A.T.3
Putney, S.D.4
Langlois, A.5
Weinhold, K.6
Robinson, J.E.7
-
121
-
-
84870361929
-
Most rhesus macaques infected with the CCR5-tropic SHIV(AD8) generate cross-reactive antibodies that neutralize multiple HIV-1 strains
-
M. Shingai, O.K. Donau, S.D. Schmidt, R. Gautam, R.J. Plishka, A. Buckler-White, R. Sadjadpour, W.R. Lee, C.C. LaBranche, and D.C. Montefiori et al. Most rhesus macaques infected with the CCR5-tropic SHIV(AD8) generate cross-reactive antibodies that neutralize multiple HIV-1 strains Proc. Natl. Acad. Sci. USA 109 2012 19769 19774
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 19769-19774
-
-
Shingai, M.1
Donau, O.K.2
Schmidt, S.D.3
Gautam, R.4
Plishka, R.J.5
Buckler-White, A.6
Sadjadpour, R.7
Lee, W.R.8
Labranche, C.C.9
Montefiori, D.C.10
-
122
-
-
84887627657
-
Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia
-
M. Shingai, Y. Nishimura, F. Klein, H. Mouquet, O.K. Donau, R. Plishka, A. Buckler-White, M. Seaman, M. Piatak Jr., and J.D. Lifson et al. Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia Nature 503 2013 277 280
-
(2013)
Nature
, vol.503
, pp. 277-280
-
-
Shingai, M.1
Nishimura, Y.2
Klein, F.3
Mouquet, H.4
Donau, O.K.5
Plishka, R.6
Buckler-White, A.7
Seaman, M.8
Piatak Jr., M.9
Lifson, J.D.10
-
123
-
-
67650453747
-
Human immunodeficiency virus type 1 elite neutralizers: Individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm
-
M.D. Simek, W. Rida, F.H. Priddy, P. Pung, E. Carrow, D.S. Laufer, J.K. Lehrman, M. Boaz, T. Tarragona-Fiol, and G. Miiro et al. Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm J. Virol. 83 2009 7337 7348
-
(2009)
J. Virol.
, vol.83
, pp. 7337-7348
-
-
Simek, M.D.1
Rida, W.2
Priddy, F.H.3
Pung, P.4
Carrow, E.5
Laufer, D.S.6
Lehrman, J.K.7
Boaz, M.8
Tarragona-Fiol, T.9
Miiro, G.10
-
124
-
-
33746555576
-
HIV/AIDS epidemiology, pathogenesis, prevention, and treatment
-
DOI 10.1016/S0140-6736(06)69157-5, PII S0140673606691575
-
V. Simon, D.D. Ho, and Q. Abdool Karim HIV/AIDS epidemiology, pathogenesis, prevention, and treatment Lancet 368 2006 489 504 (Pubitemid 44142771)
-
(2006)
Lancet
, vol.368
, Issue.9534
, pp. 489-504
-
-
Simon, V.1
Ho, D.D.2
Abdool Karim, Q.3
-
125
-
-
37849000389
-
HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane
-
Z.Y. Sun, K.J. Oh, M. Kim, J. Yu, V. Brusic, L. Song, Z. Qiao, J.H. Wang, G. Wagner, and E.L. Reinherz HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane Immunity 28 2008 52 63
-
(2008)
Immunity
, vol.28
, pp. 52-63
-
-
Sun, Z.Y.1
Oh, K.J.2
Kim, M.3
Yu, J.4
Brusic, V.5
Song, L.6
Qiao, Z.7
Wang, J.H.8
Wagner, G.9
Reinherz, E.L.10
-
126
-
-
33847278450
-
+ Memory B Cells
-
DOI 10.1016/j.immuni.2007.01.009, PII S1074761307001367
-
T. Tiller, M. Tsuiji, S. Yurasov, K. Velinzon, M.C. Nussenzweig, and H. Wardemann Autoreactivity in human IgG+ memory B cells Immunity 26 2007 205 213 (Pubitemid 46329436)
-
(2007)
Immunity
, vol.26
, Issue.2
, pp. 205-213
-
-
Tiller, T.1
Tsuiji, M.2
Yurasov, S.3
Velinzon, K.4
Nussenzweig, M.C.5
Wardemann, H.6
-
127
-
-
0025821179
-
A human monoclonal antibody against the CD4-binding site of HIV1 gp120 exhibits potent, broadly neutralizing activity
-
S.A. Tilley, W.J. Honnen, M.E. Racho, M. Hilgartner, and A. Pinter A human monoclonal antibody against the CD4-binding site of HIV1 gp120 exhibits potent, broadly neutralizing activity Res. Virol. 142 1991 247 259
-
(1991)
Res. Virol.
, vol.142
, pp. 247-259
-
-
Tilley, S.A.1
Honnen, W.J.2
Racho, M.E.3
Hilgartner, M.4
Pinter, A.5
-
128
-
-
57349127300
-
Initial B-cell responses to transmitted human immunodeficiency virus type 1: Virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia
-
G.D. Tomaras, N.L. Yates, P. Liu, L. Qin, G.G. Fouda, L.L. Chavez, A.C. Decamp, R.J. Parks, V.C. Ashley, and J.T. Lucas et al. Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia J. Virol. 82 2008 12449 12463
-
(2008)
J. Virol.
, vol.82
, pp. 12449-12463
-
-
Tomaras, G.D.1
Yates, N.L.2
Liu, P.3
Qin, L.4
Fouda, G.G.5
Chavez, L.L.6
Decamp, A.C.7
Parks, R.J.8
Ashley, V.C.9
Lucas, J.T.10
-
129
-
-
9044241681
-
Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
-
A. Trkola, M. Purtscher, T. Muster, C. Ballaun, A. Buchacher, N. Sullivan, K. Srinivasan, J. Sodroski, J.P. Moore, and H. Katinger Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1 J. Virol. 70 1996 1100 1108 (Pubitemid 26029030)
-
(1996)
Journal of Virology
, vol.70
, Issue.2
, pp. 1100-1108
-
-
Trkola, A.1
Purtscher, M.2
Muster, T.3
Ballaun, C.4
Buchacher, A.5
Sullivan, N.6
Srinivasan, K.7
Sodroski, J.8
Moore, J.P.9
Katinger, H.10
-
130
-
-
20944446452
-
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
-
DOI 10.1038/nm1244
-
A. Trkola, H. Kuster, P. Rusert, B. Joos, M. Fischer, C. Leemann, A. Manrique, M. Huber, M. Rehr, and A. Oxenius et al. Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies Nat. Med. 11 2005 615 622 (Pubitemid 40868301)
-
(2005)
Nature Medicine
, vol.11
, Issue.6
, pp. 615-622
-
-
Trkola, A.1
Kuster, H.2
Rusert, P.3
Joos, B.4
Fischer, M.5
Leemann, C.6
Manrique, A.7
Huber, M.8
Rehr, M.9
Oxenius, A.10
Weber, R.11
Stiegler, G.12
Vcelar, B.13
Katinger, H.14
Aceto, L.15
Gunthard, H.F.16
-
131
-
-
79960405099
-
Longer V1V2 region with increased number of potential N-linked glycosylation sites in the HIV-1 envelope glycoprotein protects against HIV-specific neutralizing antibodies
-
M.J. van Gils, E.M. Bunnik, B.D. Boeser-Nunnink, J.A. Burger, M. Terlouw-Klein, N. Verwer, and H. Schuitemaker Longer V1V2 region with increased number of potential N-linked glycosylation sites in the HIV-1 envelope glycoprotein protects against HIV-specific neutralizing antibodies J. Virol. 85 2011 6986 6995
-
(2011)
J. Virol.
, vol.85
, pp. 6986-6995
-
-
Van Gils, M.J.1
Bunnik, E.M.2
Boeser-Nunnink, B.D.3
Burger, J.A.4
Terlouw-Klein, M.5
Verwer, N.6
Schuitemaker, H.7
-
132
-
-
64849095775
-
Meta-analytical studies on the epidemiology, prevention, and treatment of human immunodeficiency virus infection
-
P.I. Vergidis, M.E. Falagas, and D.H. Hamer Meta-analytical studies on the epidemiology, prevention, and treatment of human immunodeficiency virus infection Infect. Dis. Clin. North Am. 23 2009 295 308
-
(2009)
Infect. Dis. Clin. North Am.
, vol.23
, pp. 295-308
-
-
Vergidis, P.I.1
Falagas, M.E.2
Hamer, D.H.3
-
133
-
-
76249083814
-
Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance
-
L. Verkoczy, M. Diaz, T.M. Holl, Y.B. Ouyang, H. Bouton-Verville, S.M. Alam, H.X. Liao, G. Kelsoe, and B.F. Haynes Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance Proc. Natl. Acad. Sci. USA 107 2010 181 186
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 181-186
-
-
Verkoczy, L.1
Diaz, M.2
Holl, T.M.3
Ouyang, Y.B.4
Bouton-Verville, H.5
Alam, S.M.6
Liao, H.X.7
Kelsoe, G.8
Haynes, B.F.9
-
134
-
-
84883348588
-
Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: Selection against membrane proximal external region-associated autoreactivity limits T-dependent responses
-
L. Verkoczy, Y. Chen, J. Zhang, H. Bouton-Verville, A. Newman, B. Lockwood, R.M. Scearce, D.C. Montefiori, S.M. Dennison, and S.M. Xia et al. Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against membrane proximal external region-associated autoreactivity limits T-dependent responses J. Immunol. 191 2013 2538 2550
-
(2013)
J. Immunol.
, vol.191
, pp. 2538-2550
-
-
Verkoczy, L.1
Chen, Y.2
Zhang, J.3
Bouton-Verville, H.4
Newman, A.5
Lockwood, B.6
Scearce, R.M.7
Montefiori, D.C.8
Dennison, S.M.9
Xia, S.M.10
-
138
-
-
70349887757
-
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
-
Protocol G Principal Investigators
-
L.M. Walker, S.K. Phogat, P.Y. Chan-Hui, D. Wagner, P. Phung, J.L. Goss, T. Wrin, M.D. Simek, S. Fling, J.L. Mitcham Protocol G Principal Investigators Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target Science 326 2009 285 289
-
(2009)
Science
, vol.326
, pp. 285-289
-
-
Walker, L.M.1
Phogat, S.K.2
Chan-Hui, P.Y.3
Wagner, D.4
Phung, P.5
Goss, J.L.6
Wrin, T.7
Simek, M.D.8
Fling, S.9
Mitcham, J.L.10
-
139
-
-
80053132436
-
Broad neutralization coverage of HIV by multiple highly potent antibodies
-
Protocol G Principal Investigators
-
L.M. Walker, M. Huber, K.J. Doores, E. Falkowska, R. Pejchal, J.P. Julien, S.K. Wang, A. Ramos, P.Y. Chan-Hui, M. Moyle Protocol G Principal Investigators Broad neutralization coverage of HIV by multiple highly potent antibodies Nature 477 2011 466 470
-
(2011)
Nature
, vol.477
, pp. 466-470
-
-
Walker, L.M.1
Huber, M.2
Doores, K.J.3
Falkowska, E.4
Pejchal, R.5
Julien, J.P.6
Wang, S.K.7
Ramos, A.8
Chan-Hui, P.Y.9
Moyle, M.10
-
140
-
-
84055181327
-
Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque
-
L.M. Walker, D. Sok, Y. Nishimura, O. Donau, R. Sadjadpour, R. Gautam, M. Shingai, R. Pejchal, A. Ramos, and M.D. Simek et al. Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque Proc. Natl. Acad. Sci. USA 108 2011 20125 20129
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 20125-20129
-
-
Walker, L.M.1
Sok, D.2
Nishimura, Y.3
Donau, O.4
Sadjadpour, R.5
Gautam, R.6
Shingai, M.7
Pejchal, R.8
Ramos, A.9
Simek, M.D.10
-
141
-
-
0041689676
-
Predominant autoantibody production by early human B cell precursors
-
DOI 10.1126/science.1086907
-
H. Wardemann, S. Yurasov, A. Schaefer, J.W. Young, E. Meffre, and M.C. Nussenzweig Predominant autoantibody production by early human B cell precursors Science 301 2003 1374 1377 (Pubitemid 37075812)
-
(2003)
Science
, vol.301
, Issue.5638
, pp. 1374-1377
-
-
Wardemann, H.1
Yurasov, S.2
Schaefer, A.3
Young, J.W.4
Meffre, E.5
Nussenzweig, M.C.6
-
142
-
-
79953653241
-
An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV
-
J.D. Watkins, N.B. Siddappa, S.K. Lakhashe, M. Humbert, A. Sholukh, G. Hemashettar, Y.L. Wong, J.K. Yoon, W. Wang, and F.J. Novembre et al. An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV PLoS ONE 6 2011 e18207
-
(2011)
PLoS ONE
, vol.6
, pp. 18207
-
-
Watkins, J.D.1
Siddappa, N.B.2
Lakhashe, S.K.3
Humbert, M.4
Sholukh, A.5
Hemashettar, G.6
Wong, Y.L.7
Yoon, J.K.8
Wang, W.9
Novembre, F.J.10
-
143
-
-
0037456827
-
Antibody neutralization and escape by HIV-1
-
DOI 10.1038/nature01470
-
X. Wei, J.M. Decker, S. Wang, H. Hui, J.C. Kappes, X. Wu, J.F. Salazar-Gonzalez, M.G. Salazar, J.M. Kilby, and M.S. Saag et al. Antibody neutralization and escape by HIV-1 Nature 422 2003 307 312 (Pubitemid 36378357)
-
(2003)
Nature
, vol.422
, Issue.6929
, pp. 307-312
-
-
Wei, X.1
Decker, J.M.2
Wang, S.3
Hui, H.4
Kappes, J.C.5
Wu, X.6
Salazar-Gonzalez, J.F.7
Salazar, M.G.8
Kilby, J.M.9
Saag, M.S.10
Komarova, N.L.11
Nowak, M.A.12
Hahn, B.H.13
Kwong, P.D.14
Shaw, G.M.15
-
144
-
-
58149376504
-
Design and expression of a dimeric form of human immunodeficiency virus type 1 antibody 2G12 with increased neutralization potency
-
A.P. West Jr., R.P. Galimidi, C.P. Foglesong, P.N. Gnanapragasam, K.E. Huey-Tubman, J.S. Klein, M.D. Suzuki, N.E. Tiangco, J. Vielmetter, and P.J. Bjorkman Design and expression of a dimeric form of human immunodeficiency virus type 1 antibody 2G12 with increased neutralization potency J. Virol. 83 2009 98 104
-
(2009)
J. Virol.
, vol.83
, pp. 98-104
-
-
West Jr., A.P.1
Galimidi, R.P.2
Foglesong, C.P.3
Gnanapragasam, P.N.4
Huey-Tubman, K.E.5
Klein, J.S.6
Suzuki, M.D.7
Tiangco, N.E.8
Vielmetter, J.9
Bjorkman, P.J.10
-
145
-
-
84864363185
-
Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120
-
A.P. West Jr., R. Diskin, M.C. Nussenzweig, and P.J. Bjorkman Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120 Proc. Natl. Acad. Sci. USA 109 2012 E2083 E2090
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
-
-
West Jr., A.P.1
Diskin, R.2
Nussenzweig, M.C.3
Bjorkman, P.J.4
-
146
-
-
84879538530
-
Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues
-
A.P. West Jr., L. Scharf, J. Horwitz, F. Klein, M.C. Nussenzweig, and P.J. Bjorkman Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues Proc. Natl. Acad. Sci. USA 110 2013 10598 10603
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 10598-10603
-
-
West Jr., A.P.1
Scharf, L.2
Horwitz, J.3
Klein, F.4
Nussenzweig, M.C.5
Bjorkman, P.J.6
-
147
-
-
84887270287
-
Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes
-
C.K. Wibmer, J.N. Bhiman, E.S. Gray, N. Tumba, S.S. Abdool Karim, C. Williamson, L. Morris, and P.L. Moore Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes PLoS Pathog. 9 2013 e1003738
-
(2013)
PLoS Pathog.
, vol.9
, pp. 1003738
-
-
Wibmer, C.K.1
Bhiman, J.N.2
Gray, E.S.3
Tumba, N.4
Abdool Karim, S.S.5
Williamson, C.6
Morris, L.7
Moore, P.L.8
-
148
-
-
77954920017
-
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
-
X. Wu, Z.Y. Yang, Y. Li, C.M. Hogerkorp, W.R. Schief, M.S. Seaman, T. Zhou, S.D. Schmidt, L. Wu, and L. Xu et al. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1 Science 329 2010 856 861
-
(2010)
Science
, vol.329
, pp. 856-861
-
-
Wu, X.1
Yang, Z.Y.2
Li, Y.3
Hogerkorp, C.M.4
Schief, W.R.5
Seaman, M.S.6
Zhou, T.7
Schmidt, S.D.8
Wu, L.9
Xu, L.10
-
149
-
-
80052942203
-
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing
-
NISC Comparative Sequencing Program
-
X. Wu, T. Zhou, J. Zhu, B. Zhang, I. Georgiev, C. Wang, X. Chen, N.S. Longo, M. Louder, K. McKee NISC Comparative Sequencing Program Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing Science 333 2011 1593 1602
-
(2011)
Science
, vol.333
, pp. 1593-1602
-
-
Wu, X.1
Zhou, T.2
Zhu, J.3
Zhang, B.4
Georgiev, I.5
Wang, C.6
Chen, X.7
Longo, N.S.8
Louder, M.9
McKee, K.10
-
150
-
-
84890222476
-
Structural Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-Recognizing Antibody 2G12
-
Y. Wu, A.P. West Jr., H.J. Kim, M.E. Thornton, A.B. Ward, and P.J. Bjorkman Structural Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-Recognizing Antibody 2G12 Cell Rep 5 2013 1443 1455
-
(2013)
Cell Rep
, vol.5
, pp. 1443-1455
-
-
Wu, Y.1
West Jr., A.P.2
Kim, H.J.3
Thornton, M.E.4
Ward, A.B.5
Bjorkman, P.J.6
-
151
-
-
70449701456
-
Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: Implications for evasion of immune responses and design of vaccine immunogens
-
X. Xiao, W. Chen, Y. Feng, Z. Zhu, P. Prabakaran, Y. Wang, M.Y. Zhang, N.S. Longo, and D.S. Dimitrov Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design of vaccine immunogens Biochem. Biophys. Res. Commun. 390 2009 404 409
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.390
, pp. 404-409
-
-
Xiao, X.1
Chen, W.2
Feng, Y.3
Zhu, Z.4
Prabakaran, P.5
Wang, Y.6
Zhang, M.Y.7
Longo, N.S.8
Dimitrov, D.S.9
-
152
-
-
84874562109
-
Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies
-
G. Yang, T.M. Holl, Y. Liu, Y. Li, X. Lu, N.I. Nicely, T.B. Kepler, S.M. Alam, H.X. Liao, and D.W. Cain et al. Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies J. Exp. Med. 210 2013 241 256
-
(2013)
J. Exp. Med.
, vol.210
, pp. 241-256
-
-
Yang, G.1
Holl, T.M.2
Liu, Y.3
Li, Y.4
Lu, X.5
Nicely, N.I.6
Kepler, T.B.7
Alam, S.M.8
Liao, H.X.9
Cain, D.W.10
-
153
-
-
77954943648
-
Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01
-
T. Zhou, I. Georgiev, X. Wu, Z.Y. Yang, K. Dai, A. Finzi, Y.D. Kwon, J.F. Scheid, W. Shi, and L. Xu et al. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01 Science 329 2010 811 817
-
(2010)
Science
, vol.329
, pp. 811-817
-
-
Zhou, T.1
Georgiev, I.2
Wu, X.3
Yang, Z.Y.4
Dai, K.5
Finzi, A.6
Kwon, Y.D.7
Scheid, J.F.8
Shi, W.9
Xu, L.10
-
154
-
-
84882589754
-
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies
-
NISC Comparative Sequencing Program
-
T. Zhou, J. Zhu, X. Wu, S. Moquin, B. Zhang, P. Acharya, I.S. Georgiev, H.R. Altae-Tran, G.Y. Chuang, M.G. Joyce NISC Comparative Sequencing Program Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies Immunity 39 2013 245 258
-
(2013)
Immunity
, vol.39
, pp. 245-258
-
-
Zhou, T.1
Zhu, J.2
Wu, X.3
Moquin, S.4
Zhang, B.5
Acharya, P.6
Georgiev, I.S.7
Altae-Tran, H.R.8
Chuang, G.Y.9
Joyce, M.G.10
-
155
-
-
33745203490
-
Distribution and three-dimensional structure of AIDS virus envelope spikes
-
P. Zhu, J. Liu, J. Bess Jr., E. Chertova, J.D. Lifson, H. Grisé, G.A. Ofek, K.A. Taylor, and K.H. Roux Distribution and three-dimensional structure of AIDS virus envelope spikes Nature 441 2006 847 852
-
(2006)
Nature
, vol.441
, pp. 847-852
-
-
Zhu, P.1
Liu, J.2
Bess Jr., J.3
Chertova, E.4
Lifson, J.D.5
Grisé, H.6
Ofek, G.A.7
Taylor, K.A.8
Roux, K.H.9
-
156
-
-
80055115557
-
Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies
-
Z. Zhu, H.R. Qin, W. Chen, Q. Zhao, X. Shen, R. Schutte, Y. Wang, G. Ofek, E. Streaker, and P. Prabakaran et al. Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies J. Virol. 85 2011 11401 11408
-
(2011)
J. Virol.
, vol.85
, pp. 11401-11408
-
-
Zhu, Z.1
Qin, H.R.2
Chen, W.3
Zhao, Q.4
Shen, X.5
Schutte, R.6
Wang, Y.7
Ofek, G.8
Streaker, E.9
Prabakaran, P.10
-
157
-
-
1542615646
-
Identifying epitopes of HIV-1 that induce protective antibodies
-
S. Zolla-Pazner Identifying epitopes of HIV-1 that induce protective antibodies Nat. Rev. Immunol. 4 2004 199 210 (Pubitemid 38339086)
-
(2004)
Nature Reviews Immunology
, vol.4
, Issue.3
, pp. 199-210
-
-
Zolla-Pazner, S.1
-
158
-
-
0034759882
-
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41
-
DOI 10.1128/JVI.75.22.10892-10905.2001
-
M.B. Zwick, A.F. Labrijn, M. Wang, C. Spenlehauer, E.O. Saphire, J.M. Binley, J.P. Moore, G. Stiegler, H. Katinger, D.R. Burton, and P.W. Parren Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41 J. Virol. 75 2001 10892 10905 (Pubitemid 33034579)
-
(2001)
Journal of Virology
, vol.75
, Issue.22
, pp. 10892-10905
-
-
Zwick, M.B.1
Labrijn, A.F.2
Wang, M.3
Spenlehauer, C.4
Ollmann Saphire, E.5
Binley, J.M.6
Moore, J.P.7
Stiegler, G.8
Katinger, H.9
Burton, D.R.10
Parren, P.W.H.I.11
-
159
-
-
11144227042
-
Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1
-
DOI 10.1128/JVI.79.2.1252-1261.2005
-
M.B. Zwick, R. Jensen, S. Church, M. Wang, G. Stiegler, R. Kunert, H. Katinger, and D.R. Burton Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1 J. Virol. 79 2005 1252 1261 (Pubitemid 40053907)
-
(2005)
Journal of Virology
, vol.79
, Issue.2
, pp. 1252-1261
-
-
Zwick, M.B.1
Jensen, R.2
Church, S.3
Wang, M.4
Stiegler, G.5
Kunert, R.6
Katinger, H.7
Burton, D.R.8
|