Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape

PLoS Pathogens

Volumn 8, Issue 5, 2012, Pages

  Bar, Katharine J ^a   Tsao, Chun yen ^b   Iyer, Shilpa S ^a   Decker, Julie M ^c   Yang, Yongping ^d   Bonsignori, Mattia ^b   Chen, Xi ^b   Hwang, Kwan Ki ^b   Montefiori, David C ^b   Liao, Hua Xin ^b   Hraber, Peter ^e   Fischer, William ^e   Li, Hui ^a   Wang, Shuyi ^a   Sterrett, Sarah ^c   Keele, Brandon F ^f   Ganusov, Vitaly V ^g   Perelson, Alan S ^e   Korber, Bette T ^e   Georgiev, Ivelin ^d   McLellan, Jason S ^d   Pavlicek, Jeffrey W ^b   Gao, Feng ^b   Haynes, Barton F ^b   Hahn, Beatrice H ^a   Kwong, Peter D ^d   Shaw, George M ^a   more..

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e LOS ALAMOS NATIONAL LABORATORY   (United States)

^f SAIC FREDERICK INC   (United States)

^g UNIVERSITY OF TENNESSEE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 160; GLYCOPROTEIN GP 41; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

ADSORPTION; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CASE REPORT; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DNA SEQUENCE; GENE SEQUENCE; GLYCOSYLATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN TISSUE; MALE; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PROGENY; PROTEIN DOMAIN; SEROCONVERSION; UNINDEXED SEQUENCE; VIRAL GENETICS; VIRUS ENVELOPE; VIRUS LOAD; VIRUS MUTATION; VIRUS REPLICATION; VIRUS RESISTANCE; ADAPTIVE IMMUNITY; DOSE RESPONSE; DRUG EFFECT; GENETICS; GENOME; HOST PATHOGEN INTERACTION; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE EVASION; IMMUNOLOGY; SERODIAGNOSIS; VIRUS GENE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ADAPTIVE IMMUNITY; AIDS VACCINES; ANTIBODIES, NEUTRALIZING; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; GENES, VIRAL; GENOME; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV INFECTIONS; HIV-1; HOST-PATHOGEN INTERACTIONS; IMMUNE EVASION; NEUTRALIZATION TESTS; VIRUS REPLICATION;

EID: 84863697528     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002721     Document Type: Article

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