-
1
-
-
0032546844
-
The HIV-1 envelope glycoproteins: Fusogens, antigens, and immunogens
-
Wyatt, R. & Sodroski, J. The HIV-1 envelope glycoproteins: Fusogens, antigens, and immunogens. Science 280, 1884-1888 (1998).
-
(1998)
Science
, vol.280
, pp. 1884-1888
-
-
Wyatt, R.1
Sodroski, J.2
-
2
-
-
0032543307
-
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
-
Kwong, P.D. et al. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 393, 648-659 (1998).
-
(1998)
Nature
, vol.393
, pp. 648-659
-
-
Kwong, P.D.1
-
3
-
-
27744597054
-
Structure of a V3-containing HIV-1 gp120 core
-
Huang, C.C. et al. Structure of a V3-containing HIV-1 gp120 core. Science 310, 1025-1028 (2005).
-
(2005)
Science
, vol.310
, pp. 1025-1028
-
-
Huang, C.C.1
-
4
-
-
33847101745
-
Structural definition of a conserved neutralization epitope on HIV-1 gp120
-
Zhou, T. et al. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature 445, 732-737 (2007).
-
(2007)
Nature
, vol.445
, pp. 732-737
-
-
Zhou, T.1
-
5
-
-
75749133275
-
Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility
-
Pancera, M. et al. Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility. Proc. Natl. Acad. Sci. USA 107, 1166-1171 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 1166-1171
-
-
Pancera, M.1
-
6
-
-
77954943648
-
Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01
-
Zhou, T. et al. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science 329, 811-817 (2010).
-
(2010)
Science
, vol.329
, pp. 811-817
-
-
Zhou, T.1
-
8
-
-
0030970693
-
Core structure of gp41 from the HIV envelope glycoprotein
-
Chan, D.C., Fass, D., Berger, J.M. & Kim, P.S. Core structure of gp41 from the HIV envelope glycoprotein. Cell 89, 263-273 (1997).
-
(1997)
Cell
, vol.89
, pp. 263-273
-
-
Chan, D.C.1
Fass, D.2
Berger, J.M.3
Kim, P.S.4
-
9
-
-
0030962291
-
Atomic structure of the ectodomain from HIV-1 gp41
-
Weissenhorn, W., Dessen, A., Harrison, S.C., Skehel, J.J. & Wiley, D.C. Atomic structure of the ectodomain from HIV-1 gp41. Nature 387, 426-430 (1997).
-
(1997)
Nature
, vol.387
, pp. 426-430
-
-
Weissenhorn, W.1
Dessen, A.2
Harrison, S.C.3
Skehel, J.J.4
Wiley, D.C.5
-
10
-
-
44449179947
-
Classification and 3D averaging with missing wedge correction in biological electron tomography
-
Bartesaghi, A. et al. Classification and 3D averaging with missing wedge correction in biological electron tomography. J. Struct. Biol. 162, 436-450 (2008).
-
(2008)
J. Struct. Biol.
, vol.162
, pp. 436-450
-
-
Bartesaghi, A.1
-
11
-
-
84860584093
-
Computational separation of conformational heterogeneity using cryoelectron tomography and 3D sub-volume averaging
-
Frank, G.A. et al. Computational separation of conformational heterogeneity using cryoelectron tomography and 3D sub-volume averaging. J. Struct. Biol. 178, 165-176 (2012).
-
(2012)
J. Struct. Biol.
, vol.178
, pp. 165-176
-
-
Frank, G.A.1
-
12
-
-
51349162563
-
Molecular architecture of native HIV-1 gp120 trimers
-
Liu, J., Bartesaghi, A., Borgnia, M.J., Sapiro, G. & Subramaniam, S. Molecular architecture of native HIV-1 gp120 trimers. Nature 455, 109-113 (2008).
-
(2008)
Nature
, vol.455
, pp. 109-113
-
-
Liu, J.1
Bartesaghi, A.2
Borgnia, M.J.3
Sapiro, G.4
Subramaniam, S.5
-
13
-
-
84872189908
-
Molecular structures of trimeric HIV-1 Env in complex with small antibody derivatives
-
Meyerson, J.R. et al. Molecular structures of trimeric HIV-1 Env in complex with small antibody derivatives. Proc. Natl. Acad. Sci. USA 110, 513-518 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 513-518
-
-
Meyerson, J.R.1
-
14
-
-
84864603281
-
Structural mechanism of trimeric HIV-1 envelope glycoprotein activation
-
Tran, E.E. et al. Structural mechanism of trimeric HIV-1 envelope glycoprotein activation. PLoS Pathog. 8, e1002797 (2012).
-
(2012)
PLoS Pathog.
, vol.8
-
-
Tran, E.E.1
-
15
-
-
79960974710
-
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures
-
Harris, A. et al. Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures. Proc. Natl. Acad. Sci. USA 108, 11440-11445 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11440-11445
-
-
Harris, A.1
-
16
-
-
0036333661
-
Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1
-
Sanders, R.W. et al. Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1. J. Virol. 76, 8875-8889 (2002).
-
(2002)
J. Virol.
, vol.76
, pp. 8875-8889
-
-
Sanders, R.W.1
-
17
-
-
79955048174
-
Quaternary structures of HIV Env immunogen exhibit conformational vicissitudes and interface diminution elicited by ligand binding
-
Moscoso, C.G. et al. Quaternary structures of HIV Env immunogen exhibit conformational vicissitudes and interface diminution elicited by ligand binding. Proc. Natl. Acad. Sci. USA 108, 6091-6096 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 6091-6096
-
-
Moscoso, C.G.1
-
18
-
-
78650426126
-
Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure
-
Wu, S.R. et al. Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure. Proc. Natl. Acad. Sci. USA 107, 18844-18849 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 18844-18849
-
-
Wu, S.R.1
-
19
-
-
84859405812
-
Fabs enable single particle cryoEM studies of small proteins
-
Wu, S. et al. Fabs enable single particle cryoEM studies of small proteins. Structure 20, 582-592 (2012).
-
(2012)
Structure
, vol.20
, pp. 582-592
-
-
Wu, S.1
-
20
-
-
33845348200
-
Frealign: High-resolution refinement of single particle structures
-
Grigorieff, N. FREALIGN: High-resolution refinement of single particle structures. J. Struct. Biol. 157, 117-125 (2007).
-
(2007)
J. Struct. Biol.
, vol.157
, pp. 117-125
-
-
Grigorieff, N.1
-
21
-
-
84868444740
-
Relion: Implementation of a Bayesian approach to cryo-EM structure determination
-
Scheres, S.H. RELION: Implementation of a Bayesian approach to cryo-EM structure determination. J. Struct. Biol. 180, 519-530 (2012).
-
(2012)
J. Struct. Biol.
, vol.180
, pp. 519-530
-
-
Scheres, S.H.1
-
22
-
-
4444221565
-
UCSF Chimera: A visualization system for exploratory research and analysis
-
Pettersen, E.F. et al. UCSF Chimera: A visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605-1612 (2004).
-
(2004)
J. Comput. Chem.
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
-
23
-
-
80052942203
-
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing
-
Wu, X. et al. Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science 333, 1593-1602 (2011).
-
(2011)
Science
, vol.333
, pp. 1593-1602
-
-
Wu, X.1
-
24
-
-
84880678141
-
Molecular architecture of the uncleaved HIV-1 envelope glycoprotein trimer
-
Mao, Y. et al. Molecular architecture of the uncleaved HIV-1 envelope glycoprotein trimer. Proc. Natl. Acad. Sci. USA 110, 12438-12443 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 12438-12443
-
-
Mao, Y.1
-
25
-
-
84859561617
-
Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops
-
Kwon, Y.D. et al. Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Proc. Natl. Acad. Sci. USA 109, 5663-5668 (2012).
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 5663-5668
-
-
Kwon, Y.D.1
-
26
-
-
84857981961
-
Structural changes in Influenza virus at low pH characterized by cryo-electron tomography
-
Fontana, J., Cardone, G., Heymann, J.B., Winkler, D.C. & Steven, A.C. Structural changes in Influenza virus at low pH characterized by cryo-electron tomography. J. Virol. 86, 2919-2929 (2012).
-
(2012)
J. Virol.
, vol.86
, pp. 2919-2929
-
-
Fontana, J.1
Cardone, G.2
Heymann, J.B.3
Winkler, D.C.4
Steven, A.C.5
-
27
-
-
79955373167
-
Structural characterization of an early fusion intermediate of influenza virus hemagglutinin
-
Xu, R. & Wilson, I.A. Structural characterization of an early fusion intermediate of influenza virus hemagglutinin. J. Virol. 85, 5172-5182 (2011).
-
(2011)
J. Virol.
, vol.85
, pp. 5172-5182
-
-
Xu, R.1
Wilson, I.A.2
-
29
-
-
0032214714
-
Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain
-
Weissenhorn, W., Carfi, A., Lee, K.H., Skehel, J.J. & Wiley, D.C. Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain. Mol. Cell 2, 605-616 (1998).
-
(1998)
Mol. Cell
, vol.2
, pp. 605-616
-
-
Weissenhorn, W.1
Carfi, A.2
Lee, K.H.3
Skehel, J.J.4
Wiley, D.C.5
-
30
-
-
0019890491
-
Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution
-
Wilson, I.A., Skehel, J.J. & Wiley, D.C. Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution. Nature 289, 366-373 (1981).
-
(1981)
Nature
, vol.289
, pp. 366-373
-
-
Wilson, I.A.1
Skehel, J.J.2
Wiley, D.C.3
-
31
-
-
0028023726
-
Structure of influenza haemagglutinin at the pH of membrane fusion
-
Bullough, P.A., Hughson, F.M., Skehel, J.J. & Wiley, D.C. Structure of influenza haemagglutinin at the pH of membrane fusion. Nature 371, 37-43 (1994).
-
(1994)
Nature
, vol.371
, pp. 37-43
-
-
Bullough, P.A.1
Hughson, F.M.2
Skehel, J.J.3
Wiley, D.C.4
-
32
-
-
84879053104
-
Influenza-virus membrane fusion by cooperative fold-back of stochastically induced hemagglutinin intermediates
-
Ivanovic, T., Choi, J.L., Whelan, S.P., van Oijen, A.M. & Harrison, S.C. Influenza-virus membrane fusion by cooperative fold-back of stochastically induced hemagglutinin intermediates. eLife 2, e00333 (2013).
-
(2013)
ELife
, vol.2
-
-
Ivanovic, T.1
Choi, J.L.2
Whelan, S.P.3
Van Oijen, A.M.4
Harrison, S.C.5
-
33
-
-
0034924823
-
Mechanisms of viral membrane fusion and its inhibition
-
Eckert, D.M. & Kim, P.S. Mechanisms of viral membrane fusion and its inhibition. Annu. Rev. Biochem. 70, 777-810 (2001).
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 777-810
-
-
Eckert, D.M.1
Kim, P.S.2
-
34
-
-
84866493348
-
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
-
Huang, J. et al. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature 491, 406-412 (2012).
-
(2012)
Nature
, vol.491
, pp. 406-412
-
-
Huang, J.1
-
35
-
-
84875551472
-
Broadly neutralizing antiviral antibodies
-
Corti, D. & Lanzavecchia, A. Broadly neutralizing antiviral antibodies. Annu. Rev. Immunol. 31, 705-742 (2013).
-
(2013)
Annu. Rev. Immunol.
, vol.31
, pp. 705-742
-
-
Corti, D.1
Lanzavecchia, A.2
-
36
-
-
84878349946
-
Structure of RSV fusion glycoprotein trimer bound to a prefusionspecific neutralizing antibody
-
McLellan, J.S. et al. Structure of RSV fusion glycoprotein trimer bound to a prefusionspecific neutralizing antibody. Science 340, 1113-1117 (2013).
-
(2013)
Science
, vol.340
, pp. 1113-1117
-
-
McLellan, J.S.1
-
37
-
-
84880061968
-
Intermediate conformations during viral fusion glycoprotein structural transition
-
Baquero, E. et al. Intermediate conformations during viral fusion glycoprotein structural transition. Curr. Opin. Virol. 3, 143-150 (2013).
-
(2013)
Curr. Opin. Virol.
, vol.3
, pp. 143-150
-
-
Baquero, E.1
-
38
-
-
84880848354
-
Electron counting and beam-induced motion correction enable near-Atomicresolution single-particle cryo-EM
-
Li, X. et al. Electron counting and beam-induced motion correction enable near-Atomicresolution single-particle cryo-EM. Nat. Methods 10, 584-590 (2013).
-
(2013)
Nat. Methods
, vol.10
, pp. 584-590
-
-
Li, X.1
-
39
-
-
0025304137
-
Refinement of the influenza virus hemagglutinin by simulated annealing
-
Weis, W.I., Brunger, A.T., Skehel, J.J. & Wiley, D.C. Refinement of the influenza virus hemagglutinin by simulated annealing. J. Mol. Biol. 212, 737-761 (1990).
-
(1990)
J. Mol. Biol.
, vol.212
, pp. 737-761
-
-
Weis, W.I.1
Brunger, A.T.2
Skehel, J.J.3
Wiley, D.C.4
-
40
-
-
0029879295
-
Computer visualization of threedimensional image data using IMOD
-
Kremer, J.R., Mastronarde, D.N. & McIntosh, J.R. Computer visualization of threedimensional image data using IMOD. J. Struct. Biol. 116, 71-76 (1996).
-
(1996)
J. Struct. Biol.
, vol.116
, pp. 71-76
-
-
Kremer, J.R.1
Mastronarde, D.N.2
McIntosh, J.R.3
-
41
-
-
0038441501
-
Accurate determination of local defocus and specimen tilt in electron microscopy
-
Mindell, J.A. & Grigorieff, N. Accurate determination of local defocus and specimen tilt in electron microscopy. J. Struct. Biol. 142, 334-347 (2003).
-
(2003)
J. Struct. Biol.
, vol.142
, pp. 334-347
-
-
Mindell, J.A.1
Grigorieff, N.2
-
42
-
-
0033377664
-
Eman: Semiautomated software for high-resolution single-particle reconstructions
-
Ludtke, S.J., Baldwin, P.R. & Chiu, W. EMAN: Semiautomated software for high-resolution single-particle reconstructions. J. Struct. Biol. 128, 82-97 (1999).
-
(1999)
J. Struct. Biol.
, vol.128
, pp. 82-97
-
-
Ludtke, S.J.1
Baldwin, P.R.2
Chiu, W.3
-
43
-
-
84869227569
-
-
2nd edn (eds Arnold, E., Himmel, D.M. & Rossmann, M.G.) Wiley
-
van Heel, M. et al. in International Tables for Crystallography Volume F: Crystallography of Biological Macromolecules 2nd edn (eds. Arnold, E., Himmel, D.M. & Rossmann, M.G.) 624-628 (Wiley, 2012).
-
(2012)
International Tables for Crystallography Volume F: Crystallography of Biological Macromolecules
, pp. 624-628
-
-
Van Heel, M.1
-
44
-
-
80855132610
-
Tilt-pair analysis of images from a range of different specimens in single-particle electron cryomicroscopy
-
Henderson, R. et al. Tilt-pair analysis of images from a range of different specimens in single-particle electron cryomicroscopy. J. Mol. Biol. 413, 1028-1046 (2011).
-
(2011)
J. Mol. Biol.
, vol.413
, pp. 1028-1046
-
-
Henderson, R.1
-
45
-
-
0142042865
-
Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy
-
Rosenthal, P.B. & Henderson, R. Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy. J. Mol. Biol. 333, 721-745 (2003).
-
(2003)
J. Mol. Biol.
, vol.333
, pp. 721-745
-
-
Rosenthal, P.B.1
Henderson, R.2
-
46
-
-
33845332754
-
EMAN2: An extensible image processing suite for electron microscopy
-
Tang, G. et al. EMAN2: An extensible image processing suite for electron microscopy. J. Struct. Biol. 157, 38-46 (2007).
-
(2007)
J. Struct. Biol.
, vol.157
, pp. 38-46
-
-
Tang, G.1
|