Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies

Immunity

Volumn 39, Issue 2, 2013, Pages 245-258

  Zhou, Tongqing ^a   Zhu, Jiang ^a   Wu, Xueling ^a   Moquin, Stephanie ^a   Zhang, Baoshan ^a   Acharya, Priyamvada ^a   Georgiev, Ivelin S ^a   Altae Tran, HanR ^a   Chuang, Gwo Yu ^a   Joyce, M Gordon ^a   DoKwon, Young ^a   Longo, Nancy S ^a   Louder, MarkK ^a   Luongo, Timothy ^a   McKee, Krisha ^a   Schramm, Chaim A ^d   Skinner, Jeff ^a   Yang, Yongping ^a   Yang, Zhongjia ^a   Zhang, Zhenhai ^d   Zheng, Anqi ^a   Bonsignori, Mattia ^e   Haynes, Barton F ^e   Scheid, Johannes F ^f   Nussenzweig, Michel C ^f   Simek, Melissa ^g   Burton, Dennis R ^h,i   Koff, WayneC ^g   Mullikin, James C ^c   Connors, Mark ^b   Shapiro, Lawrence ^a,d   Nabel, Gary J ^a   Mascola, John R ^a   Kwong, Peter D ^a   more..

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

^e DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f ROCKEFELLER UNIVERSITY   (United States)

^g INTERNATIONAL AIDS VACCINE INITIATIVE   (United States)

^h SCRIPPS RESEARCH INSTITUTE   (United States)

ⁱ MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; GLYCOPROTEIN GP 120; UNCLASSIFIED DRUG; VRC01 ANTIBODY;

ARTICLE; B LYMPHOCYTE; CELL EXPANSION; CRYSTALLIZATION; CRYSTALLOGRAPHY; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROGEN BOND; LIGHT CHAIN; MOLECULAR RECOGNITION; NONHUMAN; ONTOGENY; PHYLOGENETIC TREE; PRIORITY JOURNAL; SOMATIC MUTATION; VIRAL GENETICS; VIRUS NEUTRALIZATION;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; B-LYMPHOCYTES; BASE SEQUENCE; CRYSTALLOGRAPHY, X-RAY; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV INFECTIONS; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA;

EID: 84882589754     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2013.04.012     Document Type: Article

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