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Volumn 86, Issue 22, 2012, Pages 12115-12128

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies

(15)  Kong, Rui a,b,c   Li, Hui b   Georgiev, Ivelin c   Changela, Anita c   Bibollet Ruche, Frederic b   Decker, Julie M a   Rowland Jones, Sarah L d   Jaye, Assan e   Guan, Yongjun f   Lewis, George K f   Langedijk, Johannes P M g,i   Hahn, Beatrice H b   Kwong, Peter D c   Robinson, James E h   Shawb, George M b  


Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLYCOPROTEIN GP 120; HUMAN MONOCLONAL ANTIBODY; SOLUBLE CD4 ANTIGEN;

EID: 84869111491     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01632-12     Document Type: Article
Times cited : (25)

References (85)
  • 1
    • 37449022593 scopus 로고    scopus 로고
    • Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization.
    • Bell CH, et al. 2008. Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization. J. Mol.Biol. 375:969-978.
    • (2008) J. Mol.Biol. , vol.375 , pp. 969-978
    • Bell, C.H.1
  • 2
    • 0029957873 scopus 로고    scopus 로고
    • Human antibody responses to HIV type 1 glycoprotein 41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding
    • Binley JM, et al. 1996. Human antibody responses to HIV type 1 glycoprotein 41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding. AIDS Res. Hum. Retroviruses 12:911-924.
    • (1996) AIDS Res. Hum. Retroviruses , vol.12 , pp. 911-924
    • Binley, J.M.1
  • 3
    • 56449131391 scopus 로고    scopus 로고
    • Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C
    • Binley JM, et al. 2008. Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C. J. Virol. 82:11651-11668.
    • (2008) J. Virol. , vol.82 , pp. 11651-11668
    • Binley, J.M.1
  • 5
    • 26444450696 scopus 로고    scopus 로고
    • Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12
    • Calarese DA, et al. 2005. Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proc. Natl. Acad. Sci. U. S. A. 102:13372-13377.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 13372-13377
    • Calarese, D.A.1
  • 6
    • 12444291017 scopus 로고    scopus 로고
    • Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
    • Calarese DA, et al. 2003. Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science 300:2065-2071.
    • (2003) Science , vol.300 , pp. 2065-2071
    • Calarese, D.A.1
  • 7
    • 13844255333 scopus 로고    scopus 로고
    • Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41.
    • Cardoso RM, et al. 2005. Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41. Immunity 22:163-173.
    • (2005) Immunity , vol.22 , pp. 163-173
    • Cardoso, R.M.1
  • 8
    • 13844302894 scopus 로고    scopus 로고
    • Structure of an unliganded simian immunodeficiency virus gp120 core
    • Chen B, et al. 2005. Structure of an unliganded simian immunodeficiency virus gp120 core. Nature 433:834-841.
    • (2005) Nature , vol.433 , pp. 834-841
    • Chen, B.1
  • 9
    • 70450182950 scopus 로고    scopus 로고
    • Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120
    • Chen L, et al. 2009. Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science 326:1123-1127
    • (2009) Science , vol.326 , pp. 1123-1127
    • Chen, L.1
  • 10
    • 70450182950 scopus 로고    scopus 로고
    • Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120
    • Chen L, et al. 2009. Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science 326:1123-1127
    • (2009) Science , vol.326 , pp. 1123-1127
    • Chen, L.1
  • 11
    • 0035841649 scopus 로고    scopus 로고
    • Characterization of neutralization epitopes of simian immunodeficiency virus (SIV) recognized by rhesus monoclonal antibodies derived from monkeys infected with an attenuated SIV strain.
    • Cole KS, et al. 2001. Characterization of neutralization epitopes of simian immunodeficiency virus (SIV) recognized by rhesus monoclonal antibodies derived from monkeys infected with an attenuated SIV strain. Virology 290:59-73.
    • (2001) Virology , vol.290 , pp. 59-73
    • Cole, K.S.1
  • 12
    • 59749089778 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1V3-specific antibodies in human plasma.
    • Davis KL, et al. 2009. Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1V3-specific antibodies in human plasma. J. Virol. 83:1240-1259.
    • (2009) J. Virol. , vol.83 , pp. 1240-1259
    • Davis, K.L.1
  • 13
    • 64949147882 scopus 로고    scopus 로고
    • High titer HIV-1 V3-specific antibodies with broad reactivity but low neutralizing potency in acute infection and following vaccination
    • Davis KL, et al. 2009. High titer HIV-1 V3-specific antibodies with broad reactivity but low neutralizing potency in acute infection and following vaccination. Virology 387:414-426
    • (2009) Virology , vol.387 , pp. 414-426
    • Davis, K.L.1
  • 14
    • 20844448731 scopus 로고    scopus 로고
    • Antigenic conservation and immunogenicity of the HIV coreceptor binding site
    • Decker JM, et al. 2005. Antigenic conservation and immunogenicity of the HIV coreceptor binding site. J. Exp. Med. 201:1407-1419.
    • (2005) J. Exp. Med. , vol.201 , pp. 1407-1419
    • Decker, J.M.1
  • 15
    • 84856907465 scopus 로고    scopus 로고
    • Potent autologous and heterologous neutralizing antibody responses occur in HIV-2 infection across a broad range of infection outcomes
    • de Silva TI, et al. 2012. Potent autologous and heterologous neutralizing antibody responses occur in HIV-2 infection across a broad range of infection outcomes. J. Virol. 86:930-946.
    • (2012) J. Virol. , vol.86 , pp. 930-946
    • de Silva, T.I.1
  • 16
    • 58149399396 scopus 로고    scopus 로고
    • Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies.
    • Doria-Rose NA, et al. 2009. Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies. J. Virol. 83:188-199.
    • (2009) J. Virol. , vol.83 , pp. 188-199
    • Doria-Rose, N.A.1
  • 17
    • 0033521911 scopus 로고    scopus 로고
    • Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes
    • Gao F, et al. 1999. Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes. Nature 397:436-441
    • (1999) Nature , vol.397 , pp. 436-441
    • Gao, F.1
  • 18
    • 78349299783 scopus 로고    scopus 로고
    • Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies. PLoS Comput
    • Gnanakaran S, et al. 2010. Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies. PLoS Comput. Biol. 6:e1000955. doi:10.1371/journal.pcbi.1000955
    • (2010) Biol. , vol.6
    • Gnanakaran, S.1
  • 19
    • 70350320582 scopus 로고    scopus 로고
    • Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region
    • Gray ES, et al. 2009. Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region. J. Virol. 83:11265-11274.
    • (2009) J. Virol , vol.83 , pp. 11265-11274
    • Gray, E.S.1
  • 20
    • 69249208675 scopus 로고    scopus 로고
    • Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors
    • Gray ES, et al. 2009. Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors. J. Virol. 83:8925-8937
    • (2009) J. Virol. , vol.83 , pp. 8925-8937
    • Gray, E.S.1
  • 21
    • 62649166814 scopus 로고    scopus 로고
    • Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection
    • Guan Y, et al. 2009. Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection. Proc. Natl. Acad. Sci. U. S. A. 106:3952-3957
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 3952-3957
    • Guan, Y.1
  • 22
    • 0031777694 scopus 로고    scopus 로고
    • ceptor usage of human immunodeficiency virus type 2 primary isolates and biological clones is broad and does not correlate with their syncytium-inducing capacities
    • Guillon C, et al. 1998. Coreceptor usage of human immunodeficiency virus type 2 primary isolates and biological clones is broad and does not correlate with their syncytium-inducing capacities. J. Virol. 72:6260-6263.
    • (1998) J. Virol. , vol.72 , pp. 6260-6263
    • Guillon, C.1
  • 23
    • 0023657622 scopus 로고
    • Genome organization and transactivation of the human immunodeficiency virus type 2
    • Guyader M, et al. 1987. Genome organization and transactivation of the human immunodeficiency virus type 2. Nature 326:662-669.
    • (1987) Nature , vol.326 , pp. 662-669
    • Guyader, M.1
  • 24
    • 0034723385 scopus 로고    scopus 로고
    • AIDS as a zoonosis:scientific and public health implications
    • Hahn BH, Shaw GM, De Cock KM, Sharp PM. 2000. AIDS as a zoonosis:scientific and public health implications. Science 287:607-614.
    • (2000) Science , vol.287 , pp. 607-614
    • Hahn, B.H.1    Shaw, G.M.2    De cock, K.M.3    Sharp, P.M.4
  • 25
    • 79952368717 scopus 로고    scopus 로고
    • Structural comparison of HIV-1 envelope spikes with and without the V1/V2 loop.
    • Hu G, Liu J, Taylor KA, Roux KH. 2011. Structural comparison of HIV-1 envelope spikes with and without the V1/V2 loop. J. Virol. 85:2741-2750.
    • (2011) J. Virol , vol.85 , pp. 2741-2750
    • Hu, G.1    Liu, J.2    Taylor, K.A.3    Roux, K.H.4
  • 26
    • 27744597054 scopus 로고    scopus 로고
    • Structure of a V3-containing HIV-1 gp120 core
    • Huang CC, et al. 2005. Structure of a V3-containing HIV-1 gp120 core. Science 310:1025-1028.
    • (2005) Science , vol.310 , pp. 1025-1028
    • Huang, C.C.1
  • 27
    • 0028219306 scopus 로고
    • Studies of the conformation-dependent neutralizing epitopes of simian immunodeficiency virus envelope protein
    • Javaherian K, et al. 1994. Studies of the conformation-dependent neutralizing epitopes of simian immunodeficiency virus envelope protein. J.Virol. 68:2624-2631.
    • (1994) J.Virol , vol.68 , pp. 2624-2631
    • Javaherian, K.1
  • 28
    • 77955417928 scopus 로고    scopus 로고
    • Conserved structural elements in the V3 crown of HIV-1 gp120.
    • Jiang X, et al. 2010. Conserved structural elements in the V3 crown of HIV-1 gp120. Nat. Struct. Mol. Biol. 17:955-961.
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 955-961
    • Jiang, X.1
  • 29
    • 0026693317 scopus 로고
    • Production of human monoclonal antibodies specific for conformational and linear non-V3 epitopes of gp120
    • Karwowska S, et al. 1992. Production of human monoclonal antibodies specific for conformational and linear non-V3 epitopes of gp120. AIDS Res. Hum. Retroviruses 8:1099-1106
    • (1992) AIDS Res. Hum. Retroviruses , vol.8 , pp. 1099-1106
    • Karwowska, S.1
  • 30
    • 44649102135 scopus 로고    scopus 로고
    • Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
    • Keele BF, et al. 2008. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc. Natl. Acad. Sci. U. S. A. 105:7552-7557.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 7552-7557
    • Keele, B.F.1
  • 31
    • 84863115725 scopus 로고    scopus 로고
    • Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection
    • Kong R, et al. 2012. Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection. J. Virol. 86:947-960.
    • (2012) J. Virol , vol.86 , pp. 947-960
    • Kong, R.1
  • 32
    • 0037069682 scopus 로고    scopus 로고
    • HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites
    • Kwong PD, et al. 2002. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites. Nature 420:678-682.
    • (2002) Nature , vol.420 , pp. 678-682
    • Kwong, P.D.1
  • 33
    • 82955241840 scopus 로고    scopus 로고
    • Rational design of vaccines to elicit broadly neutralizing antibodies to HIV-1
    • Kwong PD, Mascola JR, Nabel GJ. 2011. Rational design of vaccines to elicit broadly neutralizing antibodies to HIV-1. Cold Spring Harb. Perspect.Biol. 1:a007278. doi:10.1101/cshperspect.a007278.
    • (2011) Cold Spring Harb. Perspect.Biol. , vol.1
    • Kwong, P.D.1    Mascola, J.R.2    Nabel, G.J.3
  • 34
    • 65749107719 scopus 로고    scopus 로고
    • HIV-1 and influenza antibodies: seeing antigens in new ways
    • Kwong PD, Wilson IA. 2009. HIV-1 and influenza antibodies: seeing antigens in new ways. Nat. Immunol. 10:573-578.
    • (2009) Nat.Immunol. , vol.10 , pp. 573-578
    • Kwong, P.D.1    Wilson, I.A.2
  • 35
    • 0032543307 scopus 로고    scopus 로고
    • Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody.
    • Kwong PD, et al. 1998. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 393:648-659.
    • (1998) Nature , vol.393 , pp. 648-659
    • Kwong, P.D.1
  • 36
    • 0030895233 scopus 로고    scopus 로고
    • Antigenic structure of the central conserved region of protein G of bovine respiratory syncytial virus
    • Langedijk JP, Meloen RH, Taylor G, Furze JM, van Oirschot JT. 1997. Antigenic structure of the central conserved region of protein G of bovine respiratory syncytial virus. J. Virol. 71:4055-4061.
    • (1997) J. Virol. , vol.71 , pp. 4055-4061
    • Langedijk, J.P.1    Meloen, R.H.2    Taylor, G.3    Furze, J.M.4    van Oirschot, J.T.5
  • 37
    • 79955680409 scopus 로고    scopus 로고
    • Immune and genetic correlates of vaccine protection against mucosal infection by SIV in monkeys
    • 81ra36
    • Letvin NL, et al. 2011. Immune and genetic correlates of vaccine protection against mucosal infection by SIV in monkeys. Sci. Transl. Med.3:81ra36.
    • (2011) Sci. Transl. Med , vol.3
    • Letvin, N.L.1
  • 38
    • 34948854718 scopus 로고    scopus 로고
    • Broad HIV-1 neutralization mediated by CD4-binding site antibodies
    • Li Y, et al. 2007. Broad HIV-1 neutralization mediated by CD4-binding site antibodies. Nat. Med. 13:1032-1034.
    • (2007) Nat. Med , vol.13 , pp. 1032-1034
    • Li, Y.1
  • 40
    • 0023491395 scopus 로고
    • HIV infection of primate lymphocytes and conservation of the CD4 receptor
    • McClure MO, et al. 1987. HIV infection of primate lymphocytes and conservation of the CD4 receptor. Nature 330:487-489.
    • (1987) Nature , vol.330 , pp. 487-489
    • McClure, M.O.1
  • 41
    • 0030043169 scopus 로고    scopus 로고
    • Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein.
    • Moore JP, Sodroski J. 1996. Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein.J. Virol. 70:1863-1872.
    • (1996) J.Virol , vol.70 , pp. 1863-1872
    • Moore, J.P.1    Sodroski, J.2
  • 42
    • 0344766077 scopus 로고    scopus 로고
    • Primary human immunodeficiency virus type 2 (HIV-2) isolates, like HIV-1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage
    • Morner A, et al. 1999. Primary human immunodeficiency virus type 2 (HIV-2) isolates, like HIV-1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage. J. Virol. 73:2343-2349.
    • (1999) J. Virol , vol.73 , pp. 2343-2349
    • Morner, A.1
  • 43
    • 38449120344 scopus 로고    scopus 로고
    • Competitive PCR-ELISA protocols for the quantitative and the standardized detection of viral genomes
    • Musiani M, Gallinella G, Venturoli S, Zerbini M. 2007. Competitive PCR-ELISA protocols for the quantitative and the standardized detection of viral genomes. Nat. Protoc. 2:2511-2519.
    • (2007) Nat. Protoc , vol.2 , pp. 2511-2519
    • Musiani, M.1    Gallinella, G.2    Venturoli, S.3    Zerbini, M.4
  • 44
    • 0027378573 scopus 로고
    • A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
    • Muster T, et al. 1993. A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1. J. Virol. 67:6642-6647.
    • (1993) J. Virol , vol.67 , pp. 6642-6647
    • Muster, T.1
  • 45
    • 84856890445 scopus 로고    scopus 로고
    • Potent intratype neutralizing activity distinguishes human immunodeficiency virus type 2 (HIV-2) from HIV-1
    • Ozkaya Sahin G, et al. 2012. Potent intratype neutralizing activity distinguishes human immunodeficiency virus type 2 (HIV-2) from HIV-1. J. Virol. 86:961-971.
    • (2012) J.Virol , vol.86 , pp. 961-971
    • Ozkaya Sahin, G.1
  • 46
    • 0011993562 scopus 로고
    • A conserved region at the COOH terminus of human immunodeficiency virus gp120 envelope protein contains an immunodominant epitope
    • Palker TJ, et al. 1987. A conserved region at the COOH terminus of human immunodeficiency virus gp120 envelope protein contains an immunodominant epitope. Proc. Natl. Acad. Sci. U. S. A. 84:2479-2483
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 2479-2483
    • Palker, T.J.1
  • 47
    • 75749133275 scopus 로고    scopus 로고
    • Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility
    • Pancera M, et al. 2010. Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility. Proc. Natl. Acad. Sci. U. S. A. 107:1166-1171.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 1166-1171
    • Pancera, M.1
  • 48
    • 33646146379 scopus 로고    scopus 로고
    • GP120:target for neutralizing HIV-1 antibodies
    • Pantophlet R, Burton DR. 2006. GP120: target for neutralizing HIV-1 antibodies. Annu. Rev. Immunol. 24:739-769.
    • (2006) Annu. Rev.Immunol , vol.24 , pp. 739-769
    • Pantophlet, R.1    Burton, D.R.2
  • 49
    • 38949186531 scopus 로고    scopus 로고
    • Roles of HIV-1 Env variable regions in viral neutralization and vaccine development
    • Pinter A. 2007. Roles of HIV-1 Env variable regions in viral neutralization and vaccine development. Curr. HIV Res. 5:542-553.
    • (2007) Curr. HIV Res , vol.5 , pp. 542-553
    • Pinter, A.1
  • 50
    • 0036268538 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 2
    • Reeves JD, Doms RW. 2002. Human immunodeficiency virus type 2. J.Gen. Virol. 83:1253-1265.
    • (2002) J.Gen. Virol , vol.83 , pp. 1253-1265
    • Reeves, J.D.1    Doms, R.W.2
  • 51
    • 17444384573 scopus 로고    scopus 로고
    • An unrelated monoclonal antibody neutralizes human immunodeficiency virus type 1 by binding to an artificial epitope engineered in a functionally neutral region of the viral envelope glycoproteins
    • Ren X, Sodroski J, Yang X. 2005. An unrelated monoclonal antibody neutralizes human immunodeficiency virus type 1 by binding to an artificial epitope engineered in a functionally neutral region of the viral envelope glycoproteins. J. Virol. 79:5616-5624
    • (2005) J. Virol , vol.79 , pp. 5616-5624
    • Ren, X.1    Sodroski, J.2    Yang, X.3
  • 52
    • 0028291731 scopus 로고
    • Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1
    • Roben P, et al. 1994. Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1. J. Virol.68:4821-4828.
    • (1994) J.Virol , vol.68 , pp. 4821-4828
    • Roben, P.1
  • 53
    • 18344415593 scopus 로고    scopus 로고
    • Production and characterization of SIV envelope-specific rhesus monoclonal antibodies from a macaque asymptomatically infected with a live SIV vaccine
    • Robinson JE, et al. 1998. Production and characterization of SIV envelope-specific rhesus monoclonal antibodies from a macaque asymptomatically infected with a live SIV vaccine. AIDS Res. Hum. Retroviruses 14:1253-1262
    • (1998) AIDS Res. Hum. Retroviruses , vol.14 , pp. 1253-1262
    • Robinson, J.E.1
  • 54
    • 0025066116 scopus 로고
    • Identification of conserved and variant epitopes of human immunodeficiency virus type 1 (HIV-1) gp120 by human monoclonal antibodies produced by EBV-transformed cell lines
    • Robinson JE, Holton D, Pacheco-Morell S, Liu J, McMurdo H. 1990.Identification of conserved and variant epitopes of human immunodeficiency virus type 1 (HIV-1) gp120 by human monoclonal antibodies produced by EBV-transformed cell lines. AIDS Res. Hum. Retroviruses 6:567-579.
    • (1990) AIDS Res. Hum. Retroviruses , vol.6 , pp. 567-579
    • Robinson, J.E.1    Holton, D.2    Pacheco-Morell, S.3    Liu, J.4    McMurdo, H.5
  • 55
    • 58149487645 scopus 로고    scopus 로고
    • Factors associated with the development of crossreactive neutralizing antibodies during human immunodeficiency virus type 1 infection.
    • Sather DN, et al. 2009. Factors associated with the development of crossreactive neutralizing antibodies during human immunodeficiency virus type 1 infection. J. Virol. 83:757-769.
    • (2009) J. Virol , vol.83 , pp. 757-769
    • Sather, D.N.1
  • 56
    • 52649145900 scopus 로고    scopus 로고
    • Potent antibody-mediated neutralization and evolution of antigenic escape variants of simian immunodeficiency virus strain SIVmac239 in vivo
    • Sato S, et al. 2008.Potent antibody-mediated neutralization and evolutionof antigenic escape variants of simian immunodeficiency virus strain SIV mac239 in vivo. J. Virol. 82:9739-9752
    • (2008) J. Virol , vol.82 , pp. 9739-9752
    • Sato, S.1
  • 57
    • 63849131879 scopus 로고    scopus 로고
    • Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
    • Scheid JF, et al. 2009. Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals. Nature 458:636-640
    • (2009) Nature , vol.458 , pp. 636-640
    • Scheid, J.F.1
  • 58
    • 80052925616 scopus 로고    scopus 로고
    • Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding
    • Scheid JF, et al. 2011. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science 333:1633-1637.
    • (2011) Science , vol.333 , pp. 1633-1637
    • Scheid, J.F.1
  • 59
    • 73949127978 scopus 로고    scopus 로고
    • Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies
    • Seaman MS, et al. 2010. Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies. J. Virol. 84:439-1452
    • (2010) J. Virol. , vol.84 , pp. 1439-1452
    • Seaman, M.S.1
  • 60
    • 84886705258 scopus 로고    scopus 로고
    • Origins of HIV and the AIDS pandemic. Cold Spring Harb
    • doi:10.1101/cshperspect.a006841
    • Sharp PM, Hahn BH. 2011. Origins of HIV and the AIDS pandemic. Cold Spring Harb. Perspect. Med. 1:a006841. doi:10.1101/cshperspect.a006841.
    • (2011) Perspect. Med. , vol.1
    • Sharp, P.M.1    Hahn, B.H.2
  • 61
    • 0030849537 scopus 로고    scopus 로고
    • Usage of the coreceptors CCR-5, CCR-3, and CXCR-4 by primary and cell line-adapted human immunodeficiency virus type 2
    • Sol N, et al. 1997. Usage of the coreceptors CCR-5, CCR-3, and CXCR-4 by primary and cell line-adapted human immunodeficiency virus type 2. J.Virol. 71:8237-8244
    • (1997) J.Virol. , vol.71 , pp. 8237-8244
    • Sol, N.1
  • 62
    • 69149083668 scopus 로고    scopus 로고
    • Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?
    • Stamatatos L, Morris L, Burton DR, Mascola JR.2009. Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine? Nat. Med. 15:866-870.
    • (2009) Nat. Med. , vol.15 , pp. 866-870
    • Stamatatos, L.1    Morris, L.2    Burton, D.R.3    Mascola, J.R.4
  • 63
    • 1242351232 scopus 로고    scopus 로고
    • Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D
    • Stanfield RL, Gorny MK, Williams C, Zolla-Pazner S, Wilson IA.2004.Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D. Structure 12:193-204
    • Structure , vol.12 , pp. 193-204
    • Stanfield, R.L.1    Gorny, M.K.2    Williams, C.3    Zolla-Pazner, S.4    Wilson, I.A.5
  • 64
    • 33744933182 scopus 로고    scopus 로고
    • Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity
    • Stanfield RL, Gorny MK, Zolla-Pazner S, Wilson IA.2006. Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity. J. Virol. 80:6093-6105
    • (2006) J. Virol. , vol.80 , pp. 6093-6105
    • Stanfield, R.L.1    Gorny, M.K.2    Zolla-Pazner, S.3    Wilson, I.A.4
  • 65
    • 0027256814 scopus 로고
    • Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding
    • Thali M, et al. 1993. Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding. J. Virol. 67:3978-3988
    • (1993) J. Virol. , vol.67 , pp. 3978-3988
    • Thali, M.1
  • 66
    • 36849031722 scopus 로고    scopus 로고
    • Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
    • Tiller T, et al. 2008. Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning.J. Immunol. Methods 329:112-124.
    • (2008) J.Immunol. Methods , vol.329 , pp. 112-124
    • Tiller, T.1
  • 67
    • 21044441799 scopus 로고    scopus 로고
    • Rapid and quantitative cyclization of multiple peptide loops onto synthetic scaffolds for structural mimicry of protein surfaces
    • Timmerman P, Beld J, Puijk WC, Meloen RH. 2005. Rapid and quantitative cyclization of multiple peptide loops onto synthetic scaffolds for structural mimicry of protein surfaces. ChemBioChem 6:821-824.
    • (2005) ChemBioChem , vol.6 , pp. 821-824
    • Timmerman, P.1    Beld, J.2    Puijk, W.C.3    Meloen, R.H.4
  • 68
    • 4043154176 scopus 로고    scopus 로고
    • An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus
    • Traggiai E, et al. 2004. An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus.Nat. Med. 10:871-875.
    • (2004) Nat. Med. , vol.10 , pp. 871-875
    • Traggiai, E.1
  • 69
    • 80053132436 scopus 로고    scopus 로고
    • Broad neutralization coverage of HIV by multiple highly potent antibodies
    • Walker LM, et al. 2011. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature 477:466-470.
    • (2011) Nature , vol.477 , pp. 466-470
    • Walker, L.M.1
  • 70
    • 70349887757 scopus 로고    scopus 로고
    • Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
    • Walker LM, et al. 2009. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 326:285-289.
    • (2009) Science , vol.326 , pp. 285-289
    • Walker, L.M.1
  • 71
    • 0037456827 scopus 로고    scopus 로고
    • Antibody neutralization and escape by HIV-1
    • Wei X, et al. 2003. Antibody neutralization and escape by HIV-1. Nature 422:307-312
    • (2003) Nature , vol.422 , pp. 307-312
    • Wei, X.1
  • 72
    • 0023893492 scopus 로고
    • HIV-2 antisera cross-neutralize HIV-1
    • Weiss RA, et al. 1988. HIV-2 antisera cross-neutralize HIV-1. AIDS2:95-100
    • (1988) AIDS , vol.2 , pp. 95-100
    • Weiss, R.A.1
  • 73
    • 78651241895 scopus 로고    scopus 로고
    • Molecular architectures of trimeric SIV and HIV-1 nvelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure
    • White TA, et al. 2010. Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain dependent variation in quaternary structure. PLoS Pathog.6:e1001249. doi:10.1371/journal.ppat.1001249.
    • (2010) PLoS Pathog. , vol.6
    • White, T.A.1
  • 74
    • 84865076975 scopus 로고    scopus 로고
    • Sequential evolution and escape from neutralization of simian immunodeficiency virus SIVsmE660 clones in rhesus macaques
    • Wu F, et al. 2012. Sequential evolution and escape from neutralization of simian immunodeficiency virus SIVsmE660 clones in rhesus macaques. J.Virol. 86:8835-8847
    • (2012) J. Virol. , vol.86 , pp. 8835-8847
    • Wu, F.1
  • 75
    • 78650426126 scopus 로고    scopus 로고
    • Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure
    • Wu SR, et al. 2010. Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure. Proc. Natl. Acad. Sci. U. S. A.107:18844-18849.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 18844-18849
    • Wu, S.R.1
  • 76
    • 77954920017 scopus 로고    scopus 로고
    • Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
    • Wu X, et al. 2010. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science 329:856-861.
    • (2010) Science , vol.329 , pp. 856-861
    • Wu, X.1
  • 77
    • 80052942203 scopus 로고    scopus 로고
    • Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing
    • Wu X, et al. 2011. Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science 333:1593-1602.
    • (2011) Science , vol.333 , pp. 1593-1602
    • Wu, X.1
  • 78
    • 0032543555 scopus 로고    scopus 로고
    • The antigenic structure of the HIV gp120 envelope glycoprotein
    • Wyatt R, et al. 1998. The antigenic structure of the HIV gp120 envelope glycoprotein. Nature 393:705-711
    • (1998) Nature , vol.393 , pp. 705-711
    • Wyatt, R.1
  • 79
    • 0032546844 scopus 로고    scopus 로고
    • The HIV-1 envelope glycoproteins: fusogens,antigens, and immunogens
    • Wyatt R, Sodroski J. 1998. The HIV-1 envelope glycoproteins: fusogens,antigens, and immunogens. Science 280:1884-1888
    • (1998) Science , vol.280 , pp. 1884-1888
    • Wyatt, R.1    Sodroski, J.2
  • 80
    • 77952699322 scopus 로고    scopus 로고
    • Autologous neutralizing antibodies to the transmitted/founder viruses emerge late after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys
    • Yeh WW, et al. 2010. Autologous neutralizing antibodies to the transmitted/founder viruses emerge late after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys. J. Virol. 84:6018-6032.
    • (2010) J. Virol. , vol.84 , pp. 6018-6032
    • Yeh, W.W.1
  • 81
    • 77954943648 scopus 로고    scopus 로고
    • Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01
    • Zhou T, et al. 2010. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science 329:811-817.
    • (2010) Science , vol.329 , pp. 811-817
    • Zhou, T.1
  • 82
    • 33847101745 scopus 로고    scopus 로고
    • Structural definition of a conserved neutralization epitope on HIV-1 gp120
    • Zhou T, et al. 2007. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature 445:732-737.
    • (2007) Nature , vol.445 , pp. 732-737
    • Zhou, T.1
  • 83
    • 33646744353 scopus 로고    scopus 로고
    • Improving on nature: focusing the immune response on the V3 loop
    • Zolla-Pazner S. 2005. Improving on nature: focusing the immune response on the V3 loop. Hum. Antibodies 14:69-72.
    • (2005) Hum.Antibodies , vol.14 , pp. 69-72
    • Zolla-Pazner, S.1
  • 84
    • 11144227042 scopus 로고    scopus 로고
    • Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1
    • Zwick MB, et al. 2005. Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1. J. Virol. 79:1252-1261.
    • (2005) J. Virol. , vol.79 , pp. 1252-1261
    • Zwick, M.B.1
  • 85
    • 0034759882 scopus 로고    scopus 로고
    • Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41
    • Zwick MB, et al. 2001. Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. J. Virol. 75:10892-10905
    • (2001) J. Virol. , vol.75 , pp. 10892-10905
    • Zwick, M.B.1


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