Inhibition of the HIV-1 spike by single-PG9/16-Antibody binding suggests a coordinated-activation model for its three protomeric units

Journal of Virology

Volumn 87, Issue 12, 2013, Pages 7000-7007

  Löving, Robin ^a   Sjöberg, Mathilda ^a   Wu, Shang Rung ^a,b   Binley, James M ^c   Garoff, Henrik ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GLYCOPROTEIN GP 120; NEUTRALIZING ANTIBODY; PG16 ANTIBODY; PG9 ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ARTICLE; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; CROSS LINKING; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; VIRUS ENVELOPE; VIRUS INHIBITION; VIRUS PARTICLE; VIRUS REACTIVATION; VIRUS SPIKE;

ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIGENS, CD4; BINDING SITES; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HEK293 CELLS; HIV ENVELOPE PROTEIN GP120; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; RECOMBINANT PROTEINS; VIRUS INTERNALIZATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84878566279     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00530-13     Document Type: Article

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