-
1
-
-
20944448998
-
Detection of acute infections during HIV testing in North Carolina
-
Pilcher, C. D. et al. Detection of acute infections during HIV testing in North Carolina. N. Engl. J. Med. 352, 1873-1883 (2005).
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 1873-1883
-
-
Pilcher, C.D.1
-
2
-
-
37349106345
-
Improved detection of acute HIV 1 infection in sub Saharan Africa: Development of a risk score algorithm
-
Powers, K. A. et al. Improved detection of acute HIV 1 infection in sub Saharan Africa: development of a risk score algorithm. AIDS 21, 2237-2242 (2007).
-
(2007)
AIDS
, vol.21
, pp. 2237-2242
-
-
Powers, K.A.1
-
3
-
-
2442428094
-
Blockade of attachment and fusion receptors inhibits HIV 1 infection of human cervical tissue
-
Hu, Q. et al. Blockade of attachment and fusion receptors inhibits HIV 1 infection of human cervical tissue. J. Exp. Med. 199, 1065-1075 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1065-1075
-
-
Hu, Q.1
-
4
-
-
27744571425
-
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus cell fusion
-
Veazey, R. S. et al. Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus cell fusion. Nature 438, 99-102 (2005).
-
(2005)
Nature
, vol.438
, pp. 99-102
-
-
Veazey, R.S.1
-
5
-
-
33645046393
-
Selective transmission of CCR5 utilizing HIV 1: The 'gatekeeper' problem resolved?
-
Margolis, L. & Shattock, R. Selective transmission of CCR5 utilizing HIV 1: the 'gatekeeper' problem resolved? Nature Rev. Microbiol. 4, 312-317 (2006).
-
(2006)
Nature Rev. Microbiol.
, vol.4
, pp. 312-317
-
-
Margolis, L.1
Shattock, R.2
-
6
-
-
63449103666
-
Visualizing antigen specific and infected cells in situ predicts outcomes in early viral infection
-
Li, Q. et al. Visualizing antigen specific and infected cells in situ predicts outcomes in early viral infection. Science 323, 1726-1729 (2009).
-
(2009)
Science
, vol.323
, pp. 1726-1729
-
-
Li, Q.1
-
7
-
-
21644455405
-
Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus
-
Miller, C. J. et al. Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus. J. Virol. 79, 9217-9227 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 9217-9227
-
-
Miller, C.J.1
-
8
-
-
0031958939
-
Vaginal transmission of SIV: Assessing infectivity and hormonal influences in macaques inoculated with cell free and cell associated viral stocks
-
Sodora, D. L., Gettie, A., Miller, C. J. & Marx, P. A. Vaginal transmission of SIV: assessing infectivity and hormonal influences in macaques inoculated with cell free and cell associated viral stocks. AIDS Res. Hum. Retroviruses 14, S119-S123 (1998).
-
(1998)
AIDS Res. Hum. Retroviruses
, vol.14
-
-
Sodora, D.L.1
Gettie, A.2
Miller, C.J.3
Marx, P.A.4
-
9
-
-
70350306659
-
Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus
-
Lai, S. K. et al. Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus. J. Virol. 83, 11196-11200 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 11196-11200
-
-
Lai, S.K.1
-
10
-
-
1842486661
-
The role of sexually transmitted diseases in HIV transmission
-
Galvin, S. R. & Cohen, M. S. The role of sexually transmitted diseases in HIV transmission. Nature Rev. Microbiol. 2, 33-42 (2004).
-
(2004)
Nature Rev. Microbiol.
, vol.2
, pp. 33-42
-
-
Galvin, S.R.1
Cohen, M.S.2
-
11
-
-
59249096215
-
Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV 1
-
Haaland, R. E. et al. Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV 1. PLoS Pathog. 5, e1000274 (2009).
-
(2009)
PLoS Pathog.
, vol.5
-
-
Haaland, R.E.1
-
12
-
-
44649102135
-
Identification and characterization of transmitted and early founder virus envelopes in primary HIV 1 infection
-
Keele, B. F. et al. Identification and characterization of transmitted and early founder virus envelopes in primary HIV 1 infection. Proc. Natl Acad. Sci. USA 105, 7552-7557 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 7552-7557
-
-
Keele, B.F.1
-
13
-
-
64049089430
-
Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non poisson distribution of transmitted variants
-
Abrahams, M. R. et al. Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non poisson distribution of transmitted variants. J. Virol. 83, 3556-3567 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 3556-3567
-
-
Abrahams, M.R.1
-
14
-
-
66049139947
-
Genetic identity biological phenotype and evolutionary pathways of transmitted/founder viruses in acute and early HIV 1 infection
-
Salazar Gonzalez, J. F. et al. Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV 1 infection. J. Exp. Med. 206, 1273-1289 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1273-1289
-
-
Salazar Gonzalez, J.F.1
-
15
-
-
66049157864
-
Low dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV 1
-
Keele, B. F. et al. Low dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV 1. J. Exp. Med. 206, 1117-1134 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1117-1134
-
-
Keele, B.F.1
-
16
-
-
67349101763
-
Glycerol monolaurate prevents mucosal SIV transmission
-
Li, Q. et al. Glycerol monolaurate prevents mucosal SIV transmission. Nature 458, 1034-1038 (2009).
-
(2009)
Nature
, vol.458
, pp. 1034-1038
-
-
Li, Q.1
-
17
-
-
3442876111
-
APOBEC mediated editing of viral RNA
-
Bishop, K. N., Holmes, R. K., Sheehy, A. M. & Malim, M. H. APOBEC mediated editing of viral RNA. Science 305, 645 (2004).
-
(2004)
Science
, vol.305
, pp. 645
-
-
Bishop, K.N.1
Holmes, R.K.2
Sheehy, A.M.3
Malim, M.H.4
-
18
-
-
0034598905
-
DC SIGN, a dendritic cell specific HIV 1 binding protein that enhances trans infection of T cells
-
Geijtenbeek, T. B. et al. DC SIGN, a dendritic cell specific HIV 1 binding protein that enhances trans infection of T cells. Cell 100, 587-597 (2000).
-
(2000)
Cell
, vol.100
, pp. 587-597
-
-
Geijtenbeek, T.B.1
-
19
-
-
0034605036
-
B cells of HIV 1 infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cells
-
Moir, S. et al. B cells of HIV 1 infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cells. J. Exp. Med. 192, 637-646 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 637-646
-
-
Moir, S.1
-
20
-
-
4644342929
-
+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract
-
+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J. Exp. Med. 200, 749-759 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, pp. 749-759
-
-
Brenchley, J.M.1
-
21
-
-
33845532053
-
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
-
Brenchley, J. M. et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nature Med. 12, 1365-1371 (2006).
-
(2006)
Nature Med.
, vol.12
, pp. 1365-1371
-
-
Brenchley, J.M.1
-
22
-
-
53449093632
-
Differential Th17 CD4 T cell depletion in pathogenic and nonpathogenic lentiviral infections
-
Brenchley, J. M. et al. Differential Th17 CD4 T cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 11 2, 2826-2835 (2008).
-
(2008)
Blood
, vol.11
, Issue.2
, pp. 2826-2835
-
-
Brenchley, J.M.1
-
23
-
-
47749103401
-
Induction of plasma (TRAIL) TNFR 2 Fas ligand and plasma microparticles after human immunodeficiency virus type 1 (HIV 1) transmission: Implications for HIV 1 vaccine design
-
Gasper Smith, N. et al. Induction of plasma (TRAIL), TNFR 2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV 1) transmission: implications for HIV 1 vaccine design. J. Virol. 82, 7700-7710 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 7700-7710
-
-
Gasper Smith, N.1
-
24
-
-
0032540418
-
+ T cell depletion and viral replication in SIV infection
-
+
-
+
-
(1998)
Science
, vol.280
, pp. 427-431
-
-
Veazey, R.S.1
-
25
-
-
17844374605
-
+ T cells in multiple tissues during acute SIV infection
-
+ T cells in multiple tissues during acute SIV infection. Nature 434, 1093-1097 (2005).
-
(2005)
Nature
, vol.434
, pp. 1093-1097
-
-
Mattapallil, J.J.1
-
26
-
-
68049135892
-
Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV 1 infection
-
Levesque, M. C. et al. Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV 1 infection. PLoS Med. 6, e1000107 (2009).
-
(2009)
PLoS Med.
, vol.6
-
-
Levesque, M.C.1
-
27
-
-
0028874048
-
Rapid turnover of plasma virions and CD4 lymphocytes in HIV 1 infection
-
Ho, D. D. et al. Rapid turnover of plasma virions and CD4 lymphocytes in HIV 1 infection. Nature 373, 123-126 (1995).
-
(1995)
Nature
, vol.373
, pp. 123-126
-
-
Ho, D.D.1
-
28
-
-
0032522379
-
Biological and virologic characteristics of primary HIV infection
-
Schacker, T. W., Hughes, J. P., Shea, T., Coombs, R. W. & Corey, L. Biological and virologic characteristics of primary HIV infection. Ann. Intern. Med. 128, 613-620 (1998).
-
(1998)
Ann. Intern. Med.
, vol.128
, pp. 613-620
-
-
Schacker, T.W.1
Hughes, J.P.2
Shea, T.3
Coombs, R.W.4
Corey, L.5
-
29
-
-
33749079234
-
Predictive value of plasma HIV RNA level on rate of CD4 T cell decline in untreated HIV infection
-
Rodriguez, B. et al. Predictive value of plasma HIV RNA level on rate of CD4 T cell decline in untreated HIV infection. JAMA 296, 1498-1506 (2006).
-
(2006)
JAMA
, vol.296
, pp. 1498-1506
-
-
Rodriguez, B.1
-
30
-
-
0028041344
-
+ cytotoxic T lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
-
+ cytotoxic T lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J. Virol. 68, 6103-6110 (1994).
-
(1994)
J. Virol.
, vol.68
, pp. 6103-6110
-
-
Borrow, P.1
Lewicki, H.2
Hahn, B.H.3
Shaw, G.M.4
Oldstone, M.B.5
-
31
-
-
0028337166
-
Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
-
Koup, R. A. et al. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 68, 4650-4655 (1994).
-
(1994)
J. Virol.
, vol.68
, pp. 4650-4655
-
-
Koup, R.A.1
-
32
-
-
0031048597
-
Positive selection of HIV 1 cytotoxic T lymphocyte escape variants during primary infection
-
Price, D. A. et al. Positive selection of HIV 1 cytotoxic T lymphocyte escape variants during primary infection. Proc. Natl Acad. Sci. USA 94, 1890-1895 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 1890-1895
-
-
Price, D.A.1
-
33
-
-
0001426414
-
Direct visualization of HIV 1 specific cytotoxic T lymphocytes during primary infection
-
Wilson, J. D. et al. Direct visualization of HIV 1 specific cytotoxic T lymphocytes during primary infection. AIDS 14, 225-233 (2000).
-
(2000)
AIDS
, vol.14
, pp. 225-233
-
-
Wilson, J.D.1
-
34
-
-
0037385686
-
A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T cell decay in vivo
-
Markowitz, M. et al. A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T cell decay in vivo. J. Virol. 77, 5037-5038 (2003).
-
(2003)
J. Virol.
, vol.77
, pp. 5037-5038
-
-
Markowitz, M.1
-
36
-
-
69249214157
-
+ T cells reveals a novel source of residual viremia in patients on antiretroviral therapy
-
+ T cells reveals a novel source of residual viremia in patients on antiretroviral therapy. J. Virol. 83, 8470-8481 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 8470-8481
-
-
Brennan, T.P.1
-
37
-
-
67249121143
-
Treatment intensification does not reduce residual HIV 1 viremia in patients on highly active antiretroviral therapy
-
Dinoso, J. B. et al. Treatment intensification does not reduce residual HIV 1 viremia in patients on highly active antiretroviral therapy. Proc. Natl Acad. Sci. USA 106, 9403-9408 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 9403-9408
-
-
Dinoso, J.B.1
-
38
-
-
0028912254
-
Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV and SIV infected lymph nodes
-
Finkel, T. H. et al. Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV and SIV infected lymph nodes. Nature Med. 1, 129-134 (1995).
-
(1995)
Nature Med.
, vol.1
, pp. 129-134
-
-
Finkel, T.H.1
-
39
-
-
0037343278
-
Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high level viremia
-
Silvestri, G. et al. Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high level viremia. Immunity 18, 441-452 (2003).
-
(2003)
Immunity
, vol.18
, pp. 441-452
-
-
Silvestri, G.1
-
40
-
-
0030668834
-
+ cell count, soluble immune activation markers, or combinations of HLA DR and CD38 expression
-
+ cell count, soluble immune activation markers, or combinations of HLA DR and CD38 expression. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 16, 83-92 (1997).
-
(1997)
J. Acquir. Immune Defic. Syndr. Hum. Retrovirol.
, vol.16
, pp. 83-92
-
-
Liu, Z.1
-
41
-
-
0036534655
-
Predictive value of immunologic and virologic markers after long or short duration of HIV 1 infection
-
Giorgi, J. V. et al. Predictive value of immunologic and virologic markers after long or short duration of HIV 1 infection. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 29, 346-355 (2002).
-
(2002)
J. Acquir. Immune Defic. Syndr. Hum. Retrovirol.
, vol.29
, pp. 346-355
-
-
Giorgi, J.V.1
-
42
-
-
3843056825
-
+ T cell changes independent of viral load
-
+ T cell changes independent of viral load. Blood 104, 942-947 (2004).
-
(2004)
Blood
, vol.104
, pp. 942-947
-
-
Deeks, S.G.1
-
43
-
-
68149168652
-
Microarray analysis of lymphatic tissue reveals stage specific, gene expression signatures in HIV 1 infection
-
Li, Q. et al. Microarray analysis of lymphatic tissue reveals stage specific, gene expression signatures in HIV 1 infection. J. Immunol. 183, 1975-1982 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 1975-1982
-
-
Li, Q.1
-
44
-
-
39849096860
-
Immune activation and AIDS pathogenesis
-
Sodora, D. L. & Silvestri, G. Immune activation and AIDS pathogenesis. AIDS 22, 439-446 (2008).
-
(2008)
AIDS
, vol.22
, pp. 439-446
-
-
Sodora, D.L.1
Silvestri, G.2
-
45
-
-
0033521911
-
Origin of HIV 1 in the chimpanzee Pan troglodytes troglodytes
-
Gao, F. et al. Origin of HIV 1 in the chimpanzee Pan troglodytes troglodytes. Nature 397, 436-441 (1999).
-
(1999)
Nature
, vol.397
, pp. 436-441
-
-
Gao, F.1
-
46
-
-
0034625771
-
Timing the ancestor of the HIV 1 pandemic strains
-
Korber, B. et al. Timing the ancestor of the HIV 1 pandemic strains. Science 288, 1789-1796 (2000).
-
(2000)
Science
, vol.288
, pp. 1789-1796
-
-
Korber, B.1
-
47
-
-
33745059199
-
Chimpanzee reservoirs of pandemic and nonpandemic HIV 1
-
Keele, B. F. et al. Chimpanzee reservoirs of pandemic and nonpandemic HIV 1. Science 313, 523-526 (2006).
-
(2006)
Science
, vol.313
, pp. 523-526
-
-
Keele, B.F.1
-
48
-
-
15844388931
-
Homozygous defect in HIV 1 coreceptor accounts for resistance of some multiply exposed individuals to HIV 1 infection
-
Liu, R. et al. Homozygous defect in HIV 1 coreceptor accounts for resistance of some multiply exposed individuals to HIV 1 infection. Cell 86, 367-377 (1996).
-
(1996)
Cell
, vol.86
, pp. 367-377
-
-
Liu, R.1
-
49
-
-
0038581912
-
The influence of HLA genotype on AIDS
-
Carrington, M. & O'Brien, S. J. The influence of HLA genotype on AIDS. Annu. Rev. Med. 54, 535-551 (2003).
-
(2003)
Annu. Rev. Med.
, vol.54
, pp. 535-551
-
-
Carrington, M.1
O'Brien, S.J.2
-
50
-
-
34548134145
-
A whole genome association study of major determinants for host control of HIV 1
-
Fellay, J. et al. A whole genome association study of major determinants for host control of HIV 1. Science 317, 944-947 (2007).
-
(2007)
Science
, vol.317
, pp. 944-947
-
-
Fellay, J.1
-
51
-
-
0035978824
-
Effect of a single amino acid change in MHC class i molecules on the rate of progression to AIDS
-
Gao, X. et al. Effect of a single amino acid change in MHC class I molecules on the rate of progression to AIDS. N. Engl. J. Med. 344, 1668-1675 (2001).
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1668-1675
-
-
Gao, X.1
-
52
-
-
33748067747
-
KIR/HLA pleiotropism: Protection against both HIV and opportunistic infections
-
Qi, Y. et al. KIR/HLA pleiotropism: protection against both HIV and opportunistic infections. PLoS Pathog. 2, e79 (2006).
-
(2006)
PLoS Pathog.
, vol.2
-
-
Qi, Y.1
-
53
-
-
0036699528
-
Epistatic interaction between KIR3DS1 and HLA B delays the progression to AIDS
-
Martin, M. P. et al. Epistatic interaction between KIR3DS1 and HLA B delays the progression to AIDS. Nature Genet. 31, 429-434 (2002).
-
(2002)
Nature Genet.
, vol.31
, pp. 429-434
-
-
Martin, M.P.1
-
54
-
-
34249802335
-
Innate partnership of HLA B and KIR3DL1 subtypes against HIV 1
-
Martin, M. P. et al. Innate partnership of HLA B and KIR3DL1 subtypes against HIV 1. Nature Genet. 39, 733-740 (2007).
-
(2007)
Nature Genet.
, vol.39
, pp. 733-740
-
-
Martin, M.P.1
-
55
-
-
67449101826
-
+ NK cells during acute human immunodeficiency virus type 1 infection
-
+ NK cells during acute human immunodeficiency virus type 1 infection. J. Virol. 83, 6798-6805 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 6798-6805
-
-
Alter, G.1
-
56
-
-
34248140162
-
Evolution of innate and adaptive effector cell functions during acute HIV 1 infection
-
Alter, G. et al. Evolution of innate and adaptive effector cell functions during acute HIV 1 infection. J. Infect. Dis. 195, 1452-1460 (2007).
-
(2007)
J. Infect. Dis.
, vol.195
, pp. 1452-1460
-
-
Alter, G.1
-
57
-
-
57349127300
-
Initial B cell responses to transmitted human immunodeficiency virus type 1: Virion binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti gp41 antibodies with ineffective control of initial viremia
-
Tomaras, G. D. et al. Initial B cell responses to transmitted human immunodeficiency virus type 1: virion binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti gp41 antibodies with ineffective control of initial viremia. J. Virol. 82, 12449-12463 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 12449-12463
-
-
Tomaras, G.D.1
-
58
-
-
64049116643
-
Induction of a striking systemic cytokine cascade prior to peak viremia in acute human immunodeficiency virus type 1 infection, in contrast to more modest and delayed responses in acute hepatitis B and C virus infections
-
Stacey, A. R. et al. Induction of a striking systemic cytokine cascade prior to peak viremia in acute human immunodeficiency virus type 1 infection, in contrast to more modest and delayed responses in acute hepatitis B and C virus infections. J. Virol. 83, 3719-3733 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 3719-3733
-
-
Stacey, A.R.1
-
59
-
-
41849142985
-
Simian immunodeficiency virus induced mucosal interleukin 17 deficiency promotes Salmonella dissemination from the gut
-
Raffatellu, M. et al. Simian immunodeficiency virus induced mucosal interleukin 17 deficiency promotes Salmonella dissemination from the gut. Nature Med. 14, 421-428 (2008).
-
(2008)
Nature Med.
, vol.14
, pp. 421-428
-
-
Raffatellu, M.1
-
60
-
-
33847188790
-
Early immune activation in gut associated and peripheral lymphoid tissue during acute HIV infection
-
Nilsson, J. et al. Early immune activation in gut associated and peripheral lymphoid tissue during acute HIV infection. AIDS 21, 565-574 (2007).
-
(2007)
AIDS
, vol.21
, pp. 565-574
-
-
Nilsson, J.1
-
61
-
-
0033543965
-
+ T cells from virus induced depletion in SCID mice transplanted with human cells
-
Lapenta, C. et al. Type I interferon is a powerful inhibitor of in vivo HIV 1 infection and preserves human CD4+ T cells from virus induced depletion in SCID mice transplanted with human cells. Virology 263, 78-88 (1999).
-
(1999)
Virology
, vol.263
, pp. 78-88
-
-
Lapenta, C.1
-
62
-
-
33749511112
-
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia
-
de Jong, M. D. et al. Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nature Med. 12, 1203-1207 (2006).
-
(2006)
Nature Med.
, vol.12
, pp. 1203-1207
-
-
De Jong, M.D.1
-
63
-
-
34547814128
-
Interferon mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome
-
Cameron, M. J. et al. Interferon mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome. J. Virol. 81, 8692-8706 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 8692-8706
-
-
Cameron, M.J.1
-
64
-
-
33745837477
-
Similar changes in plasmacytoid dendritic cell and CD4 T cell counts during primary HIV 1 infection and treatment
-
Killian, M. S., Fujimura, S. H., Hecht, F. M. & Levy, J. A. Similar changes in plasmacytoid dendritic cell and CD4 T cell counts during primary HIV 1 infection and treatment. AIDS 20, 1247-1252 (2006).
-
(2006)
AIDS
, vol.20
, pp. 1247-1252
-
-
Killian, M.S.1
Fujimura, S.H.2
Hecht, F.M.3
Levy, J.A.4
-
65
-
-
58149380860
-
Primary infection with simian immunodeficiency virus: Plasmacytoid dendritic cell homing to lymph nodes, type i interferon, and immune suppression
-
Malleret, B. et al. Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I interferon, and immune suppression. Blood 11 2, 4598-4608 (2008).
-
(2008)
Blood
, vol.11
, Issue.2
, pp. 4598-4608
-
-
Malleret, B.1
-
66
-
-
0037192549
-
+ dendritic cells with reduced CD80 and CD86 expression in lymphoid tissue during acute HIV 1 infection
-
+ dendritic cells with reduced CD80 and CD86 expression in lymphoid tissue during acute HIV 1 infection. AIDS 16, 683-692 (2002).
-
(2002)
AIDS
, vol.16
, pp. 683-692
-
-
Lore, K.1
-
67
-
-
27644513772
-
Endocytosis of HIV 1 activates plasmacytoid dendritic cells via Toll like receptor viral RNA interactions
-
Beignon, A. S. et al. Endocytosis of HIV 1 activates plasmacytoid dendritic cells via Toll like receptor viral RNA interactions. J. Clin. Invest. 115, 3265-3275 (2005).
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 3265-3275
-
-
Beignon, A.S.1
-
68
-
-
2442684197
-
HIV 1 infected monocyte derived dendritic cells do not undergo maturation but can elicit IL 10 production and T cell regulation
-
Granelli Piperno, A., Golebiowska, A., Trumpfheller, C., Siegal, F. P. & Steinman, R. M. HIV 1 infected monocyte derived dendritic cells do not undergo maturation but can elicit IL 10 production and T cell regulation. Proc. Natl Acad. Sci. USA 101, 7669-7674 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 7669-7674
-
-
Granelli Piperno, A.1
Golebiowska, A.2
Trumpfheller, C.3
Siegal, F.P.4
Steinman, R.M.5
-
69
-
-
34147115208
-
+ T cell proliferation by inducing indoleamine 2, 3 dioxygenase in plasmacytoid dendritic cells
-
Boasso, A. et al. HIV inhibits CD4+ T cell proliferation by inducing indoleamine 2, 3 dioxygenase in plasmacytoid dendritic cells. Blood 109, 3351-3359 (2007).
-
(2007)
Blood
, vol.109
, pp. 3351-3359
-
-
Boasso, A.1
-
70
-
-
55849140547
-
HIV activated human plasmacytoid DCs induce Tregs through an indoleamine 2, 3 dioxygenase dependent mechanism
-
Manches, O. et al. HIV activated human plasmacytoid DCs induce Tregs through an indoleamine 2, 3 dioxygenase dependent mechanism. J. Clin. Invest. 118, 3431-3439 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3431-3439
-
-
Manches, O.1
-
71
-
-
64249124659
-
+ T cells in acute HIV 1 infection
-
Sabado, R. L. et al. In vitro priming recapitulates in vivo HIV 1 specific T cell responses, revealing rapid loss of virus reactive CD4+ T cells in acute HIV 1 infection. PLoS ONE. 4, e4256 (2009).
-
(2009)
PLoS ONE.
, vol.4
-
-
Sabado, R.L.1
-
72
-
-
40349112705
-
Innate immune responses in primary HIV 1 infection
-
Borrow, P. & Bhardwaj, N. Innate immune responses in primary HIV 1 infection. Curr. Opin. HIV AIDS 3, 36-44 (2008).
-
(2008)
Curr. Opin. HIV AIDS
, vol.3
, pp. 36-44
-
-
Borrow, P.1
Bhardwaj, N.2
-
73
-
-
35448994462
-
Neuroinvasion of fluorescein positive monocytes in acute simian immunodeficiency virus infection
-
Clay, C. C. et al. Neuroinvasion of fluorescein positive monocytes in acute simian immunodeficiency virus infection. J. Virol. 81, 12040-12048 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 12040-12048
-
-
Clay, C.C.1
-
74
-
-
34548009372
-
HIV modulates the expression of ligands important in triggering natural killer cell cytotoxic responses on infected primary T cell blasts
-
Ward, J. et al. HIV modulates the expression of ligands important in triggering natural killer cell cytotoxic responses on infected primary T cell blasts. Blood 110, 1207-1214 (2007).
-
(2007)
Blood
, vol.110
, pp. 1207-1214
-
-
Ward, J.1
-
75
-
-
67449147145
-
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV 1 infection
-
Goonetilleke, N. et al. The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV 1 infection. J. Exp. Med. 206, 1253-1272 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1253-1272
-
-
Goonetilleke, N.1
-
76
-
-
60549091350
-
Cytokine induced memory like natural killer cells
-
Cooper, M. A. et al. Cytokine induced memory like natural killer cells. Proc. Natl Acad. Sci. USA 106, 1915-1919 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 1915-1919
-
-
Cooper, M.A.1
-
77
-
-
59049094662
-
Adaptive immune features of natural killer cells
-
Sun, J. C., Beilke, J. N. & Lanier, L. L. Adaptive immune features of natural killer cells. Nature 457, 557-561 (2009).
-
(2009)
Nature
, vol.457
, pp. 557-561
-
-
Sun, J.C.1
Beilke, J.N.2
Lanier, L.L.3
-
78
-
-
62849091888
-
Biomarkers of cervicovaginal inflammation for the assessment of microbicide safety
-
Cummins, J. E. Jr & Doncel, G. F. Biomarkers of cervicovaginal inflammation for the assessment of microbicide safety. Sex. Transm. Dis. 36, S84-S91 (2009).
-
(2009)
Sex. Transm. Dis.
, vol.36
-
-
Cummins Jr, J.E.1
Doncel, G.F.2
-
79
-
-
17844376742
-
+ T cells
-
Li, Q. et al. Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells. Nature 434, 1148-1152 (2005).
-
(2005)
Nature
, vol.434
, pp. 1148-1152
-
-
Li, Q.1
-
80
-
-
40449100795
-
+ T cell responses
-
+ T cell responses. J. Immunol. 180, 350-360 (2008).
-
(2008)
J. Immunol.
, vol.180
, pp. 350-360
-
-
Mueller, Y.M.1
-
81
-
-
0027979037
-
+ T cells with a predominant Vβ usage during the primary immune response to HIV
-
Pantaleo, G. et al. Major expansion of CD8+ T cells with a predominant Vβ usage during the primary immune response to HIV. Nature 370, 463-467 (1994).
-
(1994)
Nature
, vol.370
, pp. 463-467
-
-
Pantaleo, G.1
-
82
-
-
0041828179
-
Dynamics of HIV viremia and antibody seroconversion in plasma donors: Implications for diagnosis and staging of primary HIV infection
-
Fiebig, E. W. et al. Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection. AIDS 17, 1871-1879 (2003).
-
(2003)
AIDS
, vol.17
, pp. 1871-1879
-
-
Fiebig, E.W.1
-
83
-
-
23844539631
-
Human immunodeficiency virus mutations during the first month of infection are preferentially found in known cytotoxic T lymphocyte epitopes
-
Bernardin, F., Kong, D., Peddada, L., Baxter Lowe, L. A. & Delwart, E. Human immunodeficiency virus mutations during the first month of infection are preferentially found in known cytotoxic T lymphocyte epitopes. J. Virol. 79, 11523-11528 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 11523-11528
-
-
Bernardin, F.1
Kong, D.2
Peddada, L.3
Baxter Lowe, L.A.4
Delwart, E.5
-
84
-
-
11144357869
-
Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV 1 infection
-
Draenert, R. et al. Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV 1 infection. J. Exp. Med. 199, 905-915 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 905-915
-
-
Draenert, R.1
-
85
-
-
9244254245
-
+ cytotoxic T lymphocyte response
-
Jones, N. A. et al. Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response. J. Exp. Med. 200, 1243-1256 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1243-1256
-
-
Jones, N.A.1
-
86
-
-
65749116175
-
Antigen processing influences HIV specific cytotoxic T lymphocyte immunodominance
-
Tenzer, S. et al. Antigen processing influences HIV specific cytotoxic T lymphocyte immunodominance. Nature Immunol. 10, 636-646 (2009).
-
(2009)
Nature Immunol.
, vol.10
, pp. 636-646
-
-
Tenzer, S.1
-
87
-
-
67449119122
-
Kinetics of expansion of epitope specific T cell responses during primary HIV 1 infection
-
Turnbull, E. L. et al. Kinetics of expansion of epitope specific T cell responses during primary HIV 1 infection. J. Immunol. 182, 7131-7145 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 7131-7145
-
-
Turnbull, E.L.1
-
88
-
-
59649108841
-
+ T cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1
-
+ T cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1. J. Virol. 83, 1845-1855 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 1845-1855
-
-
Wang, Y.E.1
-
89
-
-
67650924875
-
+ T cells
-
+ T cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells. J. Virol. 83, 7641-7648 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 7641-7648
-
-
Streeck, H.1
-
90
-
-
43549109265
-
Transmission of HIV 1 Gag immune escape mutations is associated with reduced viral load in linked recipients
-
Goepfert, P. A. et al. Transmission of HIV 1 Gag immune escape mutations is associated with reduced viral load in linked recipients. J. Exp. Med. 205, 1009-1017 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1009-1017
-
-
Goepfert, P.A.1
-
91
-
-
0028145416
-
Virus escape from CTL recognition
-
Koup, R. A. Virus escape from CTL recognition. J. Exp. Med. 180, 779-782 (1994).
-
(1994)
J. Exp. Med.
, vol.180
, pp. 779-782
-
-
Koup, R.A.1
-
92
-
-
16944365445
-
Antiviral pressure exerted by HIV 1 specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
-
Borrow, P. et al. Antiviral pressure exerted by HIV 1 specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus. Nature Med. 3, 205-211 (1997).
-
(1997)
Nature Med.
, vol.3
, pp. 205-211
-
-
Borrow, P.1
-
93
-
-
0036113306
-
Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection
-
O'Connor, D. H. et al. Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection. Nature Med. 8, 493-499 (2002).
-
(2002)
Nature Med.
, vol.8
, pp. 493-499
-
-
O'Connor, D.H.1
-
94
-
-
1842741699
-
HIV evolution: CTL escape mutation and reversion after transmission
-
Leslie, A. J. et al. HIV evolution: CTL escape mutation and reversion after transmission. Nature Med. 10, 282-289 (2004).
-
(2004)
Nature Med.
, vol.10
, pp. 282-289
-
-
Leslie, A.J.1
-
95
-
-
27144513224
-
+ T cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV 1) sequence diversity and reveals constraints on HIV 1 evolution
-
+ T cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV 1) sequence diversity and reveals constraints on HIV 1 evolution. J. Virol. 79, 13239-13249 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 13239-13249
-
-
Allen, T.M.1
-
96
-
-
20244386270
-
Rapid viral escape at an immunodominant simian human immunodeficiency virus cytotoxic T lymphocyte epitope exacts a dramatic fitness cost
-
Fernandez, C. S. et al. Rapid viral escape at an immunodominant simian human immunodeficiency virus cytotoxic T lymphocyte epitope exacts a dramatic fitness cost. J. Virol. 79, 5721-5731 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 5721-5731
-
-
Fernandez, C.S.1
-
97
-
-
33645240933
-
Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1
-
Martinez Picado, J. et al. Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. J. Virol. 80, 3617-3623 (2006).
-
(2006)
J. Virol.
, vol.80
, pp. 3617-3623
-
-
Martinez Picado, J.1
-
98
-
-
36048949732
-
Escape from the dominant HLA B27 restricted cytotoxic T lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication
-
Schneidewind, A. et al. Escape from the dominant HLA B27 restricted cytotoxic T lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication. J. Virol. 81, 12382-12393 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 12382-12393
-
-
Schneidewind, A.1
-
99
-
-
50949117244
-
Marked epitope and allele specific differences in rates of mutation in human immunodeficiency type 1 (HIV 1) Gag Pol and Nef cytotoxic T lymphocyte epitopes in acute/early HIV 1 infection
-
Brumme, Z. L. et al. Marked epitope and allele specific differences in rates of mutation in human immunodeficiency type 1 (HIV 1) Gag, Pol, and Nef cytotoxic T lymphocyte epitopes in acute/early HIV 1 infection. J. Virol. 82, 9216-9227 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 9216-9227
-
-
Brumme, Z.L.1
-
100
-
-
33645768069
-
Inefficient cytotoxic T lymphocyte mediated killing of HIV 1 infected cells in vivo
-
Asquith, B., Edwards, C. T., Lipsitch, M. & McLean, A. R. Inefficient cytotoxic T lymphocyte mediated killing of HIV 1 infected cells in vivo. PLoS Biol. 4, e90 (2006).
-
(2006)
PLoS Biol.
, vol.4
-
-
Asquith, B.1
Edwards, C.T.2
Lipsitch, M.3
McLean, A.R.4
-
101
-
-
34547138161
-
Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA B*5703 restricted Gag epitope in chronic human immunodeficiency virus type 1 infection
-
Crawford, H. et al. Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA B*5703 restricted Gag epitope in chronic human immunodeficiency virus type 1 infection. J. Virol. 81, 8346-8351 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 8346-8351
-
-
Crawford, H.1
-
102
-
-
0037302428
-
Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV 1) specific T cell responses directed against the entire expressed HIV 1 genome demonstrate broadly directed responses, but no correlation to viral load
-
Addo, M. M. et al. Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV 1) specific T cell responses directed against the entire expressed HIV 1 genome demonstrate broadly directed responses, but no correlation to viral load. J. Virol. 77, 2081-2092 (2003).
-
(2003)
J. Virol.
, vol.77
, pp. 2081-2092
-
-
Addo, M.M.1
-
103
-
-
0037007670
-
+ T cells
-
+ T cells. Nature 417, 95-98 (2002).
-
(2002)
Nature
, vol.417
, pp. 95-98
-
-
Douek, D.C.1
-
104
-
-
0032941595
-
+ T cells are detectable in most individuals with active HIV 1 infection, but decline with prolonged viral suppression
-
+ T cells are detectable in most individuals with active HIV 1 infection, but decline with prolonged viral suppression. Nature Med. 5, 518-525 (1999).
-
(1999)
Nature Med.
, vol.5
, pp. 518-525
-
-
Pitcher, C.J.1
-
105
-
-
4043176043
-
Comprehensive analysis of human immunodeficiency virus type 1 specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides
-
Kaufmann, D. E. et al. Comprehensive analysis of human immunodeficiency virus type 1 specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides. J. Virol. 78, 4463-4477 (2004).
-
(2004)
J. Virol.
, vol.78
, pp. 4463-4477
-
-
Kaufmann, D.E.1
-
106
-
-
0035660401
-
+ T cells during primary HIV 1 infection
-
+ T cells during primary HIV 1 infection. Eur. J. Immunol. 31, 3782-3788 (2001).
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 3782-3788
-
-
Oxenius, A.1
-
107
-
-
1642403506
-
Association of strong virus specific CD4 T cell responses with efficient natural control of primary HIV 1 infection
-
Gloster, S. E. et al. Association of strong virus specific CD4 T cell responses with efficient natural control of primary HIV 1 infection. AIDS 18, 749-755 (2004).
-
(2004)
AIDS
, vol.18
, pp. 749-755
-
-
Gloster, S.E.1
-
108
-
-
0030665257
-
+ T cell responses associated with control of viremia
-
+ T cell responses associated with control of viremia. Science 278, 1447-1450 (1997).
-
(1997)
Science
, vol.278
, pp. 1447-1450
-
-
Rosenberg, E.S.1
-
111
-
-
0035282444
-
Skewed maturation of memory HIV specific CD8 T lymphocytes
-
Champagne, P. et al. Skewed maturation of memory HIV specific CD8 T lymphocytes. Nature 410, 106-111 (2001).
-
(2001)
Nature
, vol.410
, pp. 106-111
-
-
Champagne, P.1
-
112
-
-
40349086873
-
T cell responses in primary HIV 1 infection
-
Streeck, H., van Bockel, D. & Kelleher, A. T cell responses in primary HIV 1 infection. Curr. Opin. HIV AIDS 3, 52-59 (2008).
-
(2008)
Curr. Opin. HIV AIDS
, vol.3
, pp. 52-59
-
-
Streeck, H.1
Van Bockel, D.2
Kelleher, A.3
-
113
-
-
58149267963
-
Immune control of an SIV challenge by a T cell based vaccine in rhesus monkeys
-
Liu, J. et al. Immune control of an SIV challenge by a T cell based vaccine in rhesus monkeys. Nature 457, 87-91 (2009).
-
(2009)
Nature
, vol.457
, pp. 87-91
-
-
Liu, J.1
-
114
-
-
19944427950
-
HIV specific cytotoxic T cells from long term survivors select a unique T cell receptor
-
Dong, T. et al. HIV specific cytotoxic T cells from long term survivors select a unique T cell receptor. J. Exp. Med. 200, 1547-1557 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1547-1557
-
-
Dong, T.1
-
115
-
-
33646472100
-
+ T cell responses strongly associated with delayed disease progression cross recognize epitope variants efficiently
-
+ T cell responses strongly associated with delayed disease progression cross recognize epitope variants efficiently. J. Immunol. 176, 6130-6146 (2006).
-
(2006)
J. Immunol.
, vol.176
, pp. 6130-6146
-
-
Turnbull, E.L.1
-
116
-
-
0037456827
-
Antibody neutralization and escape by HIV 1
-
Wei, X. et al. Antibody neutralization and escape by HIV 1. Nature 422, 307-312 (2003).
-
(2003)
Nature
, vol.422
, pp. 307-312
-
-
Wei, X.1
-
117
-
-
0037389643
-
Rapid evolution of the neutralizing antibody response to HIV type 1 infection
-
Richman, D. D., Wrin, T., Little, S. J. & Petropoulos, C. J. Rapid evolution of the neutralizing antibody response to HIV type 1 infection. Proc. Natl Acad. Sci. USA 100, 4144-4149 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 4144-4149
-
-
Richman, D.D.1
Wrin, T.2
Little, S.J.3
Petropoulos, C.J.4
-
118
-
-
34249940652
-
Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection
-
Gray, E. S. et al. Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection. J. Virol. 81, 6187-6196 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 6187-6196
-
-
Gray, E.S.1
-
119
-
-
69149083668
-
Neutralizing antibodies generated during natural HIV 1 infection: Good news for an HIV 1 vaccine?
-
Stamatatos, L., Morris, L., Burton, D. R. & Mascola, J. R. Neutralizing antibodies generated during natural HIV 1 infection: good news for an HIV 1 vaccine? Nature Med. 15, 866-870 (2009).
-
(2009)
Nature Med.
, vol.15
, pp. 866-870
-
-
Stamatatos, L.1
Morris, L.2
Burton, D.R.3
Mascola, J.R.4
-
120
-
-
70350320582
-
Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region
-
Gray, E. S. et al. Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region. J. Virol. 83, 11265-11274 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 11265-11274
-
-
Gray, E.S.1
-
121
-
-
12144289425
-
Envelope constrained neutralization sensitive HIV 1 after heterosexual transmission
-
Derdeyn, C. A. et al. Envelope constrained neutralization sensitive HIV 1 after heterosexual transmission. Science 303, 2019-2022 (2004).
-
(2004)
Science
, vol.303
, pp. 2019-2022
-
-
Derdeyn, C.A.1
-
122
-
-
33947635198
-
The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti HIV 1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes
-
Alam, S. M. et al. The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti HIV 1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes. J. Immunol. 178, 4424-4435 (2007).
-
(2007)
J. Immunol.
, vol.178
, pp. 4424-4435
-
-
Alam, S.M.1
-
123
-
-
37349057483
-
Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: Antibody binding kinetics, induction, and potential for regulation in acute infection
-
Alam, S. M. et al. Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection. J. Virol. 82, 115-125 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 115-125
-
-
Alam, S.M.1
-
124
-
-
34548577658
-
A comparative immunogenicity study of HIV 1 virus like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120
-
Crooks, E. T. et al. A comparative immunogenicity study of HIV 1 virus like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120. Virology 366, 245-262 (2007).
-
(2007)
Virology
, vol.366
, pp. 245-262
-
-
Crooks, E.T.1
-
125
-
-
55549118890
-
Deceptive imprinting and immune refocusing in vaccine design
-
Tobin, G. J. et al. Deceptive imprinting and immune refocusing in vaccine design. Vaccine 26, 6189-6199 (2008).
-
(2008)
Vaccine
, vol.26
, pp. 6189-6199
-
-
Tobin, G.J.1
-
126
-
-
0034958413
-
Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural killer effector cells
-
Forthal, D. N., Landucci, G. & Daar, E. S. Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural killer effector cells. J. Virol. 75, 6953-6961 (2001).
-
(2001)
J. Virol.
, vol.75
, pp. 6953-6961
-
-
Forthal, D.N.1
Landucci, G.2
Daar, E.S.3
-
127
-
-
13944279109
-
Detection of antibody dependent complement mediated inactivation of both autologous and heterologous virus in primary human immunodeficiency virus type 1 infection
-
Aasa Chapman, M. M. et al. Detection of antibody dependent complement mediated inactivation of both autologous and heterologous virus in primary human immunodeficiency virus type 1 infection. J. Virol. 79, 2823-2830 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 2823-2830
-
-
Aasa Chapman, M.M.1
-
128
-
-
13544252604
-
Neutralizing as well as non neutralizing polyclonal immunoglobulin (Ig)G from infected patients capture HIV 1 via antibodies directed against the principal immunodominant domain of gp41
-
Burrer, R., Haessig Einius, S., Aubertin, A. M. & Moog, C. Neutralizing as well as non neutralizing polyclonal immunoglobulin (Ig)G from infected patients capture HIV 1 via antibodies directed against the principal immunodominant domain of gp41. Virology 333, 102-113 (2005).
-
(2005)
Virology
, vol.333
, pp. 102-113
-
-
Burrer, R.1
Haessig Einius, S.2
Aubertin, A.M.3
Moog, C.4
-
129
-
-
38849090714
-
The c3 v4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C infection
-
Moore, P. L. et al. The c3 v4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C infection. J. Virol. 82, 1860-1869 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 1860-1869
-
-
Moore, P.L.1
-
130
-
-
12444291017
-
Antibody domain exchange is an immunological solution to carbohydrate cluster recognition
-
Calarese, D. A. et al. Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science 300, 2065-2071 (2003).
-
(2003)
Science
, vol.300
, pp. 2065-2071
-
-
Calarese, D.A.1
-
131
-
-
0037069682
-
HIV 1 evades antibody mediated neutralization through conformational masking of receptor binding sites
-
Kwong, P. D. et al. HIV 1 evades antibody mediated neutralization through conformational masking of receptor binding sites. Nature 420, 678-682 (2002).
-
(2002)
Nature
, vol.420
, pp. 678-682
-
-
Kwong, P.D.1
-
132
-
-
4544379899
-
Structure and mechanistic analysis of the anti human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope
-
Ofek, G. et al. Structure and mechanistic analysis of the anti human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope. J. Virol. 78, 10724-10737 (2004).
-
(2004)
J. Virol.
, vol.78
, pp. 10724-10737
-
-
Ofek, G.1
-
133
-
-
33845995027
-
Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV 1 antibody 4E10
-
Cardoso, R. M. et al. Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV 1 antibody 4E10. J. Mol. Biol. 365, 1533-1544 (2007).
-
(2007)
J. Mol. Biol.
, vol.365
, pp. 1533-1544
-
-
Cardoso, R.M.1
-
134
-
-
34247106331
-
An affinity enhanced neutralizing antibody against the membrane proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10
-
Nelson, J. D. et al. An affinity enhanced neutralizing antibody against the membrane proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10. J. Virol. 81, 4033-4043 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 4033-4043
-
-
Nelson, J.D.1
-
135
-
-
64049092486
-
In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth
-
Shen, X. et al. In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth. J. Virol. 83, 3617-3625 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 3617-3625
-
-
Shen, X.1
-
136
-
-
33646780263
-
Antibody polyspecificity and neutralization of HIV 1: A hypothesis
-
Haynes, B. F., Moody, M. A., Verkoczy, L., Kelsoe, G. & Alam, S. M. Antibody polyspecificity and neutralization of HIV 1: a hypothesis. Hum. Antibodies 14, 59-67 (2005).
-
(2005)
Hum. Antibodies
, vol.14
, pp. 59-67
-
-
Haynes, B.F.1
Moody, M.A.2
Verkoczy, L.3
Kelsoe, G.4
Alam, S.M.5
-
137
-
-
0025789621
-
Lymphoid germinal centers are reservoirs of human immunodeficiency virus type 1 RNA
-
Fox, C. H. et al. Lymphoid germinal centers are reservoirs of human immunodeficiency virus type 1 RNA. J. Infect. Dis. 164, 1051-1057 (1991).
-
(1991)
J. Infect. Dis.
, vol.164
, pp. 1051-1057
-
-
Fox, C.H.1
-
138
-
-
0025942043
-
Lymphoid organs function as major reservoirs for human immunodeficiency virus
-
Pantaleo, G. et al. Lymphoid organs function as major reservoirs for human immunodeficiency virus. Proc. Natl Acad. Sci. USA 88, 9838-9842 (1991).
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 9838-9842
-
-
Pantaleo, G.1
-
139
-
-
0029034517
-
Analysis of apoptosis in lymph nodes of HIV infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden
-
Muro Cacho, C. A., Pantaleo, G. & Fauci, A. S. Analysis of apoptosis in lymph nodes of HIV infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden. J. Immunol. 154, 5555-5566 (1995).
-
(1995)
J. Immunol.
, vol.154
, pp. 5555-5566
-
-
Muro Cacho, C.A.1
Pantaleo, G.2
Fauci, A.S.3
-
140
-
-
34147119210
-
Early depletion of proliferating B cells of germinal center in rapidly progressive simian immunodeficiency virus infection
-
Zhang, Z. Q. et al. Early depletion of proliferating B cells of germinal center in rapidly progressive simian immunodeficiency virus infection. Virology 361, 455-464 (2007).
-
(2007)
Virology
, vol.361
, pp. 455-464
-
-
Zhang, Z.Q.1
-
141
-
-
0033951746
-
Protection of macaques against vaginal transmission of a pathogenic HIV 1/SIV chimeric virus by passive infusion of neutralizing antibodies
-
Mascola, J. R. et al. Protection of macaques against vaginal transmission of a pathogenic HIV 1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nature Med. 6, 207-210 (2000).
-
(2000)
Nature Med.
, vol.6
, pp. 207-210
-
-
Mascola, J.R.1
-
142
-
-
34548496893
-
Fc receptor but not complement binding is important in antibody protection against HIV
-
Hessell, A. J. et al. Fc receptor but not complement binding is important in antibody protection against HIV. Nature 449, 101-104 (2007).
-
(2007)
Nature
, vol.449
, pp. 101-104
-
-
Hessell, A.J.1
-
143
-
-
68349160853
-
Effective, low titer antibody protection against low dose repeated mucosal SHIV challenge in macaques
-
Hessell, A. J. et al. Effective, low titer antibody protection against low dose repeated mucosal SHIV challenge in macaques. Nature Med. 15, 951-954 (2009).
-
(2009)
Nature Med.
, vol.15
, pp. 951-954
-
-
Hessell, A.J.1
-
144
-
-
67249131966
-
Broadly neutralizing human anti HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers
-
Hessell, A. J. et al. Broadly neutralizing human anti HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers. PLoS Pathog. 5, e1000433 (2009).
-
(2009)
PLoS Pathog.
, vol.5
-
-
Hessell, A.J.1
-
145
-
-
68949110126
-
+ T cells reduce virus replication but do not protect from simian immunodeficiency virus disease progression
-
+ T cells reduce virus replication but do not protect from simian immunodeficiency virus disease progression. J. Immunol. 183, 706-717 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 706-717
-
-
Engram, J.C.1
-
146
-
-
73349094086
-
Vaccination with ALVAC and AIDSVAX to prevent HIV 1 infection in Thailand
-
20 Oct doi:10.1056/NEJMoa0908492
-
Rerks Ngarm, S. et al. Vaccination with ALVAC and AIDSVAX to prevent HIV 1 infection in Thailand. N. Engl. J. Med. 20 Oct 2009 (doi:10.1056/ NEJMoa0908492).
-
(2009)
N. Engl. J. Med.
-
-
Rerks Ngarm, S.1
-
147
-
-
58149143041
-
Macaques vaccinated with live attenuated SIV control replication of heterologous virus
-
Reynolds, M. R. et al. Macaques vaccinated with live attenuated SIV control replication of heterologous virus. J. Exp. Med. 205, 2537-2550 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2537-2550
-
-
Reynolds, M.R.1
-
148
-
-
48249088137
-
Dynamics of immune escape during HIV/SIV infection
-
Althaus, C. L. & De Boer, R. J. Dynamics of immune escape during HIV/SIV infection. PLoS Comput. Biol. 4, e1000103 (2008).
-
(2008)
PLoS Comput. Biol.
, vol.4
-
-
Althaus, C.L.1
De Boer, R.J.2
-
149
-
-
10644239910
-
T cell cross reactivity and conformational changes during TCR engagement
-
Lee, J. K. et al. T cell cross reactivity and conformational changes during TCR engagement. J. Exp. Med. 200, 1455-1466 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1455-1466
-
-
Lee, J.K.1
-
150
-
-
48749130188
-
A centralized gene based HIV 1 vaccine elicits broad cross clade cellular immune responses in rhesus monkeys
-
Santra, S. et al. A centralized gene based HIV 1 vaccine elicits broad cross clade cellular immune responses in rhesus monkeys. Proc. Natl Acad. Sci. USA 105, 10489-10494 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 10489-10494
-
-
Santra, S.1
-
151
-
-
72949114547
-
HIV 1 mosaic antigens expand cellular immune breadth and depth in rhesus monkeys
-
Paris
-
Barouch, D. & Korber, B. HIV 1 mosaic antigens expand cellular immune breadth and depth in rhesus monkeys. Abstr. S06 04 AIDS vaccine conference 2009, Paris (2009)
-
(2009)
Abstr. S06 04 AIDS Vaccine Conference 2009
-
-
Barouch, D.1
Korber, B.2
-
153
-
-
33845433434
-
Randomized, double blind, placebo controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV 1 vaccine among injection drug users in Bangkok, Thailand
-
Pitisuttithum, P. et al. Randomized, double blind, placebo controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV 1 vaccine among injection drug users in Bangkok, Thailand. J. Infect. Dis. 194, 1661-1671 (2006).
-
(2006)
J. Infect. Dis.
, vol.194
, pp. 1661-1671
-
-
Pitisuttithum, P.1
-
154
-
-
56649114351
-
HIV 1 vaccine induced immunity in the test of concept Step Study: A case cohort analysis
-
McElrath, M. J. et al. HIV 1 vaccine induced immunity in the test of concept Step Study: a case cohort analysis. Lancet 372, 1894-1905 (2008).
-
(2008)
Lancet
, vol.372
, pp. 1894-1905
-
-
McElrath, M.J.1
-
155
-
-
56649105122
-
Efficacy assessment of a cell mediated immunity HIV 1 vaccine (the Step Study): A double blind, randomised, placebo controlled, test of concept trial
-
Buchbinder, S. P. et al. Efficacy assessment of a cell mediated immunity HIV 1 vaccine (the Step Study): a double blind, randomised, placebo controlled, test of concept trial. Lancet 372, 1881-1893 (2008).
-
(2008)
Lancet
, vol.372
, pp. 1881-1893
-
-
Buchbinder, S.P.1
-
156
-
-
29244455769
-
Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag
-
Casimiro, D. R. et al. Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag. J. Virol. 79, 15547-15555 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 15547-15555
-
-
Casimiro, D.R.1
-
157
-
-
61949216736
-
Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge
-
Hansen, S. G. et al. Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge. Nature Med. 15, 293-299 (2009).
-
(2009)
Nature Med.
, vol.15
, pp. 293-299
-
-
Hansen, S.G.1
-
158
-
-
44049108744
-
Toward an AIDS vaccine
-
Walker, B. D. & Burton, D. R. Toward an AIDS vaccine. Science 320, 760-764 (2008).
-
(2008)
Science
, vol.320
, pp. 760-764
-
-
Walker, B.D.1
Burton, D.R.2
-
159
-
-
58149375456
-
Elite control of HIV infection: Implications for vaccine design
-
Baker, B. M., Block, B. L., Rothchild, A. C. & Walker, B. D. Elite control of HIV infection: implications for vaccine design. Expert Opin. Biol. Ther. 9, 55-69 (2009).
-
(2009)
Expert Opin. Biol. Ther.
, vol.9
, pp. 55-69
-
-
Baker, B.M.1
Block, B.L.2
Rothchild, A.C.3
Walker, B.D.4
-
160
-
-
47749101640
-
-
(eds. Koff, W. C., Kahn, P. & Gust, I. D.) Caister Academic, UK
-
Wong, S. B. J. & Siliciano, R. F. in AIDS Vaccine Development: Challenges and Opportunities (eds. Koff, W. C., Kahn, P. & Gust, I. D.) 17-22 (Caister Academic, UK, 2007).
-
(2007)
AIDS Vaccine Development: Challenges and Opportunities
, pp. 17-22
-
-
Wong, S.B.J.1
Siliciano, R.F.2
|