Viral Escape from HIV-1 Neutralizing Antibodies Drives Increased Plasma Neutralization Breadth through Sequential Recognition of Multiple Epitopes and Immunotypes

PLoS Pathogens

Volumn 9, Issue 10, 2013, Pages

  Wibmer, Constantinos Kurt ^a,b   Bhiman, Jinal N ^a,b   Gray, Elin S ^a,e   Tumba, Nancy ^a   Abdool Karim, Salim S ^c   Williamson, Carolyn ^d   Morris, Lynn ^a,b   Moore, Penny L ^a,b  

^a NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^c UNIVERSITY OF KWAZULU NATAL   (South Africa)

^d UNIVERSITY OF CAPE TOWN   (South Africa)

^e EDITH COWAN UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; COMPLEMENTARY DNA; EPITOPE; GLYCAN; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; RNA;

ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; DEGLYCOSYLATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE AMPLIFICATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE RESPONSE; IMMUNIZATION; NEUTRALIZATION ASSAY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; QUANTITATIVE ASSAY; SEQUENTIAL RECOGNITION; SINGLE GENOME AMPLIFICATION; VIRUS ATTACHMENT; VIRUS LOAD; VIRUS RESISTANCE;

ANTIBODIES, NEUTRALIZING; ANTIBODY SPECIFICITY; ANTIGENS, CD4; COHORT STUDIES; EPITOPES; FEMALE; HIV ANTIBODIES; HIV INFECTIONS; HIV-1; HUMANS; IMMUNE EVASION;

EID: 84887270287     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003738     Document Type: Article

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