Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus

Annual Review of Immunology

Volumn 24, Issue , 2006, Pages 541-570

  Jung, David ^a   Giallourakis, Cosmas ^b   Mostoslavsky, Raul ^a   Alt, Frederick W ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Allelic exclusion; Gene expression; IgH; Lymphocyte development; Transcriptional control elements

Indexed keywords

CIS ACTING ELEMENT; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; LYMPHOCYTE ANTIGEN RECEPTOR;

ALLELIC EXCLUSION; ANTIBODY RESPONSE; CELL TYPE; CHROMATIN STRUCTURE; DNA STRAND BREAKAGE; ENZYME ACTIVITY; FEEDBACK SYSTEM; GENE EXPRESSION REGULATION; GENE LOCUS; GENE REARRANGEMENT; GENE STRUCTURE; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RECEPTOR GENE; REVIEW; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION;

ANIMALS; ANTIBODY DIVERSITY; B-LYMPHOCYTES; FEEDBACK; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, TRANSGENIC; MODELS, GENETIC; MODELS, IMMUNOLOGICAL; RECOMBINATION, GENETIC;

EID: 33646181086     PISSN: 07320582     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.immunol.23.021704.115830     Document Type: Review

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