Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1

Journal of Virology

Volumn 79, Issue 2, 2005, Pages 1252-1261

  Zwick, Michael B ^a   Jensen, Richard ^a   Church, Sarah ^a   Wang, Meng ^a   Stiegler, Gabriela ^b   Kunert, Renate ^b   Katinger, Hermann ^b   Burton, Dennis R ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF AGRICULTURAL SCIENCES   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ANTIGEN; ASPARTIC ACID; EPITOPE; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; GLYCOPROTEIN GP 41 MEMBRANE PROXIMAL EXTERNAL REGION; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; LYSINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2F5; MONOCLONAL ANTIBODY 4E10; MONOCLONAL ANTIBODY B12; NEUTRALIZING ANTIBODY; PEPTIDE; PEPTIDE T20; PHENYLALANINE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ALANINE SCANNING MUTAGENESIS; AMINO ACID SUBSTITUTION; ARTICLE; DRUG DESIGN; HUMAN IMMUNODEFICIENCY VIRUS 1; MEMBRANE FUSION; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; VACCINE PRODUCTION; VIRUS ENVELOPE; VIRUS ENVELOPE FUSION; VIRUS MUTANT; VIRUS NEUTRALIZATION;

AIDS VACCINES; AMINO ACID SEQUENCE; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; NEUTRALIZATION TESTS;

EID: 11144227042     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.2.1252-1261.2005     Document Type: Article

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