Directed polymerase evolution

FEBS Letters

Volumn 588, Issue 2, 2014, Pages 219-229

  Chen, Tingjian ^a   Romesberg, Floyd E ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Directed evolution; Modified nucleotide; Polymerase; Protein engineering

Indexed keywords

DNA POLYMERASE; RNA POLYMERASE;

BINDING AFFINITY; BIOTINYLATION; CATALYSIS; CODON; DNA RECOMBINATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME SYNTHESIS; ESCHERICHIA COLI; GENE REPLICATION; GENETIC TRANSCRIPTION; GENETIC TRANSFORMATION; MOLECULAR EVOLUTION; MOLECULAR RECOGNITION; MUTAGENESIS; NONHUMAN; PHYSICAL CHEMISTRY; POLYMERASE CHAIN REACTION; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FOLDING; REVIEW; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; THERMOSTABILITY; THERMUS; THERMUS AQUATICUS; THERMUS BROCKIANUS; THERMUS OSHIMAI; THERMUS THERMOPHILUS;

DIRECTED EVOLUTION; MODIFIED NUCLEOTIDE; POLYMERASE; PROTEIN ENGINEERING;

DIRECTED MOLECULAR EVOLUTION; DNA-DIRECTED DNA POLYMERASE; DNA-DIRECTED RNA POLYMERASES; HUMANS; MUTATION;

EID: 84892371909     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.10.040     Document Type: Review

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