Evolution of a T7 RNA polymerase variant that transcribes 2′-O-methyl RNA

Nature Biotechnology

Volumn 22, Issue 9, 2004, Pages 1155-1160

  Chelliserrykattil, Jijumon ^a   Ellington, Andrew D ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVITY-BASED METHODS; RNA POLYMERASE; TRANSCRIPTION;

BIODEGRADATION; BIOTECHNOLOGY; CELLS; ENZYMES; PHARMACOKINETICS; STABILIZATION;

RNA;

2' O METHYL RNA; DNA; ENZYME VARIANT; HYDROXYL GROUP; NUCLEIC ACID; NUCLEOTIDE; RIBOSE; RNA; RNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIOPHAGE T7; CONTROLLED STUDY; DNA DEGRADATION; DNA MODIFICATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ESCHERICHIA COLI; MOLECULAR EVOLUTION; NONHUMAN; NUCLEIC ACID SYNTHESIS; PRIORITY JOURNAL; PROTEIN PROCESSING; RNA DEGRADATION; RNA STABILITY; RNA TRANSCRIPTION;

DIRECTED MOLECULAR EVOLUTION; DNA-DIRECTED RNA POLYMERASES; ESCHERICHIA COLI; METHYLATION; PROTEIN ENGINEERING; RNA PROCESSING, POST-TRANSCRIPTIONAL; TRANSCRIPTION, GENETIC; VARIATION (GENETICS); VIRAL PROTEINS;

ESCHERICHIA COLI; NEGIBACTERIA; UNIDENTIFIED BACTERIOPHAGE;

EID: 4444326623     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt1001     Document Type: Article

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