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Volumn 4, Issue 2, 2008, Pages
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How protein stability and new functions trade off
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Author keywords
[No Author keywords available]
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Indexed keywords
ECONOMIC AND SOCIAL EFFECTS;
STABILITY;
DESTABILIZING EFFECT;
DIRECTED EVOLUTION;
ENZYMATIC FUNCTIONS;
NEW FUNCTIONS;
PROTEIN STABILITY;
PROTEIN THERMODYNAMIC STABILITY;
STABILITY EFFECTS;
STABILITY FUNCTION;
STABILIZING EFFECTS;
TRADE OFF;
ENZYMES;
ADAPTATION;
ARTICLE;
ENZYME ACTIVITY;
ENZYME SPECIFICITY;
POINT MUTATION;
PROTEIN ANALYSIS;
PROTEIN FOLDING;
PROTEIN FUNCTION;
PROTEIN STABILITY;
PROTEIN STRUCTURE;
AMINO ACID SEQUENCE;
CHEMICAL MODEL;
CHEMICAL STRUCTURE;
CHEMISTRY;
COMPUTER SIMULATION;
ENZYME STABILITY;
GENETICS;
METHODOLOGY;
MOLECULAR GENETICS;
MUTATION;
SEQUENCE ANALYSIS;
SITE DIRECTED MUTAGENESIS;
STRUCTURE ACTIVITY RELATION;
ENZYME;
AMINO ACID SEQUENCE;
COMPUTER SIMULATION;
ENZYME STABILITY;
ENZYMES;
MODELS, CHEMICAL;
MODELS, MOLECULAR;
MOLECULAR SEQUENCE DATA;
MUTAGENESIS, SITE-DIRECTED;
MUTATION;
PROTEIN FOLDING;
SEQUENCE ANALYSIS, PROTEIN;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 40149099484
PISSN: 1553734X
EISSN: 15537358
Source Type: Journal
DOI: 10.1371/journal.pcbi.1000002 Document Type: Article |
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Times cited : (444)
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References (58)
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