Directed Evolution of DNA Polymerase, RNA Polymerase and Reverse Transcriptase Activity in a Single Polypeptide

Journal of Molecular Biology

Volumn 361, Issue 3, 2006, Pages 537-550

  Ong, Jennifer L ^a   Loakes, David ^a   Jaroslawski, Szymon ^a   Too, Kathleen ^a   Holliger, Philipp ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

directed evolution; DNA polymerases; enzyme evolution; PCR; protein engineering

Indexed keywords

DEOXYRIBONUCLEOTIDE; DNA DIRECTED DNA POLYMERASE BETA; DNA POLYMERASE; POLYPEPTIDE; RIBONUCLEOTIDE; RNA DIRECTED DNA POLYMERASE; RNA POLYMERASE;

ARTICLE; CATALYSIS; DIRECTED MOLECULAR EVOLUTION; DNA RNA HYBRIDIZATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ENZYME SYNTHESIS; GENE AMPLIFICATION; GENE REPLICATION; GENETIC VARIABILITY; NONHUMAN; NUCLEIC ACID PROBE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; RNA SYNTHESIS; THERMUS AQUATICUS; WILD TYPE;

THERMUS AQUATICUS;

EID: 33746347051     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.06.050     Document Type: Article

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