Directed evolution of DNA polymerases for next-generation sequencing

Angewandte Chemie - International Edition

Volumn 49, Issue 34, 2010, Pages 5921-5924

  Leconte, Aaron M ^a   Patel, Maha P ^a   Sass, Lauryn E ^b   McInemey, Peter ^b   Jarosz, Mirna ^b   Kung, Li ^b   Bowers, Jayson L ^b   Buzby, Philip R ^b   Efcavitch, J William ^b   Romesberg, Floyd E ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Building 700 ^*  (United States)

Author keywords

Directed evolution; DNA sequencing; Nucleotides; Taq polymerase

Indexed keywords

ACTIVITY-BASED; DIRECTED EVOLUTION; DNA POLYMERASE; DNA SEQUENCING; PHAGE DISPLAY;

BIOLOGY; DNA; HIGHWAY ACCIDENTS; NUCLEOTIDES; POLYMERS;

GENE ENCODING;

TAQ POLYMERASE;

ARTICLE; CHEMISTRY; DIRECTED MOLECULAR EVOLUTION; DNA SEQUENCE; GENETICS; METABOLISM; MUTATION; PROTEIN TERTIARY STRUCTURE;

DIRECTED MOLECULAR EVOLUTION; MUTATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, DNA; TAQ POLYMERASE;

EID: 77955587009     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201001607     Document Type: Article

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