Missense meanderings in sequence space: A biophysical view of protein evolution

Nature Reviews Genetics

Volumn 6, Issue 9, 2005, Pages 678-687

  DePristo, Mark A ^a   Weinreich, Daniel M ^a   Hartl, Daniel L ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; ALPHA SYNUCLEIN; BUTYRYL COENZYME A DEHYDROGENASE; GAMMA SECRETASE; HEMOGLOBIN; HUNTINGTIN; PRESENILIN 1; PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ALPHA 1 ANTITRYPSIN DEFICIENCY; ALZHEIMER DISEASE; BIOPHYSICS; CYSTIC FIBROSIS; ENZYME DEFICIENCY; HUMAN; HUNTINGTON CHOREA; MISSENSE MUTATION; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MOLECULAR MODEL; NATURAL SELECTION; PARKINSON DISEASE; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STABILITY; REVIEW; SICKLE CELL ANEMIA;

ADAPTATION, BIOLOGICAL; BIOPHYSICS; DNA; EVOLUTION, MOLECULAR; MODELS, GENETIC; MUTATION, MISSENSE; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEINS; SELECTION (GENETICS);

EID: 23944490117     PISSN: 14710056     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrg1672     Document Type: Review

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