Expanding the Substrate Repertoire of a DNA Polymerase by Directed Evolution

Journal of the American Chemical Society

Volumn 126, Issue 6, 2004, Pages 1748-1754

  Fa, Ming ^a   Radeghieri, Annalisa ^a   Henry, Allison A ^a   Romesberg, Floyd E ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; BIOTECHNOLOGY; ENZYMES; NUCLEIC ACIDS; POLYMERS; SUBSTRATES;

MUTANTS; OLIGONUCLEOTIDES;

DNA;

2' O METHYL RIBONUCLEOSIDE TRIPHOSPHATE; DNA POLYMERASE; POLYMER; PRIMER DNA; RIBONUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIOPHAGE; BIOTECHNOLOGY; DIRECTED MOLECULAR EVOLUTION; DNA MODIFICATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ENGINEERING; ENZYME SPECIFICITY; ENZYME SUBSTRATE; MUTANT; NONHUMAN; NUCLEIC ACID IMMOBILIZATION; POLYMERIZATION; PROTEIN DNA INTERACTION;

EID: 1242314258     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja038525p     Document Type: Article

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