A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 7, 1998, Pages 3402-3407

  Astatke, Mekbib ^a,b   Ng, Kimmie ^b   Grindley, Nigel D F ^b   Joyce, Catherine M ^b  

^a Life Technologies Inc   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA; NUCLEOSIDE TRIPHOSPHATE; RNA POLYMERASE;

ARTICLE; BACTERIAL MUTATION; DNA SEQUENCE; ENZYME ANALYSIS; ENZYME BINDING; ESCHERICHIA COLI; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA ANALYSIS; STRUCTURE ANALYSIS;

BINDING SITES; DNA POLYMERASE I; ESCHERICHIA COLI; GLUTAMINE; MUTATION; PROTEIN FOLDING; RIBONUCLEOTIDES;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0032584219     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.7.3402     Document Type: Article

References (36)

1. Joyce, C. M. & Steitz, T. A. (1994) Annu. Rev. Biochem. 63, 777-822.
2. Joyce, C. M. & Steitz, T. A. (1995) J. Bacteriol. 177, 6321-6329.
3. Sousa, R. (1996) Trends Biochem. Sci. 21, 186-190.
4. Ollis, D. L., Brick, P., Hamlin, R., Xuong, N. G. & Steitz, T. A. (1985) Nature (London) 313, 762-766.
5. Priestle, J. P. (1991) J. Appl. Cryst. 24, 946-950.
6. Pelletier, H., Sawaya, M. R., Kumar, A., Wilson, S. H. & Kraut, J. (1994) Science 264, 1891-1903.
7. Doublié, S., Tabor, S., Long, A., Richardson, C. C. & Ellenberger, T. (1997) Nature (London) 391, 251-258.
8. Astatke, M., Grindley, N. D. F. & Joyce, C. M. (1995) J. Biol. Chem. 270, 1945-1954.
9. Tabor, S. & Richardson, C. C. (1995) Proc. Natl. Acad. Sci. USA 92, 6339-6343.
10. Mizrahi, V. & Huberts, P. (1996) Nucleic Acids Res. 24, 4845-4852.
11. Astatke, M., Grindley, N. D. F. & Joyce, C. M. (1998) J. Mol. Biol. 278, in press.
12. Gao, G., Orlova, M., Georgiadis, M. M., Hendrickson, W. A. & Goff, S. P. (1997) Proc. Natl. Acad. Sci. USA 94, 407-411.
13. Sousa, R. & Padilla, R. (1995) EMBO J. 14, 4609-4621.
14. Polesky, A. H., Steitz, T. A., Grindley, N. D. F. & Joyce, C. M. (1990) J. Biol. Chem. 265, 14579-14591.
15. Joyce, C. M. & Derbyshire, V. (1994) Methods Enzymol. 262, 3-13.
16. Polesky, A. H., Dahlberg, M. E., Benkovic, S. J., Grindley, N. D. F. & Joyce, C. M. (1992) J. Biol. Chem. 267, 8417-8428.
17. Carroll, S. S., Cowart, M. & Benkovic, S. J. (1991) Biochemistry 30, 804-813.
18. Derbyshire, V., Freemont, P. S., Sanderson, M. R., Beese, L., Friedman, J. M., Joyce, C. M. & Steitz, T. A. (1988) Science 240, 199-201.
19. Barnes, W. M. (1978) J. Mol. Biol. 119, 83-99.
20. Sanger, F., Nicklen, S. & Coulson, A. R. (1977) Proc. Natl. Acad. Sci. USA 74, 5463-5467.
21. Ide, H., Yagi, R., Yamaoka, T. & Kimura, Y. (1993) Nucleic Acids Symp. Ser. 29, 133-134.
22. Dahlberg, M. E. & Benkovic, S. J. (1991) Biochemistry 30, 4835-4843.
23. Kornberg, A. & Baker, T. A. (1992) DNA Replication (Freeman, San Francisco).
24. Braithwaite, D. K. & Ito, J. (1993) Nucleic Acids Res. 21, 787-802.
25. Donlin, M. J. & Johnson, K. A. (1994) Biochemistry 33, 14908-14917.
26. Georgiadis, M. M., Jessen, S. M., Ogata, C. M., Telesnitsky, A., Goff, S. P. & Hendrickson, W. A. (1995) Structure 3, 879-892.
27. Delarue, M., Poch, O., Tordo, N., Moras, D. & Argos, P. (1990) Protein Eng. 3, 461-467.
28. Joyce, C. M. (1997) Proc. Natl. Acad. Sci. USA 94, 1619-1622.
29. Poch, O., Sauvaget, I., Delarue, M. & Tordo, N. (1989) EMBO J. 8, 3867-3874.
30. Wang, J., Sattar, A. K. M. A., Wang, C. C., Karam, J. D., Konigsberg, W. H. & Steitz, T. A. (1997) Cell 89, 1087-1099.
31. Huang, Y., Beaudry, A., McSwiggen, J. & Sousa, R. (1997) Biochemistry 36, 13718-13728.
32. Fedoroff, O. Y., Salazar, M. & Reid, B. R. (1993) J. Mol. Biol. 233, 509-523.
33. Hall, K. B. & McLaughlin, L. W. (1991) Biochemistry 30, 10606-10613.
34. Jacobo-Molina, A., Ding, J., Nanni, R. G., Clark, A. D., Jr., Lu, X., Tantillo, C., Williams, R. L., Kamer, G., Ferris, A. L., Clark, P., Hizi, A., Hughes, S. H. & Arnold, E. (1993) Proc. Natl. Acad. Sci. USA 90, 6320-6324.
35. Eom, S. H., Wang, J. & Steitz, T. A. (1996) Nature (London) 382, 278-281.
36. Kiefer, J. R., Mao, C., Braman, J. C. & Beese, L. S. (1998) Nature (London) 391, 304-307.