-
1
-
-
77956277702
-
Challenges in the chemical synthesis of average sized proteins: sequential vs. convergent ligation of multiple peptide fragments
-
Lee J.Y., Bang D. Challenges in the chemical synthesis of average sized proteins: sequential vs. convergent ligation of multiple peptide fragments. Biopolymers 2010, 94:441-447.
-
(2010)
Biopolymers
, vol.94
, pp. 441-447
-
-
Lee, J.Y.1
Bang, D.2
-
2
-
-
84875241247
-
Shine a light on immobilized enzymes: real-time sensing in solid supported biocatalysts
-
Bolivar J.M., et al. Shine a light on immobilized enzymes: real-time sensing in solid supported biocatalysts. Trends Biotechnol. 2013, 31:194-203.
-
(2013)
Trends Biotechnol.
, vol.31
, pp. 194-203
-
-
Bolivar, J.M.1
-
3
-
-
84876206827
-
Removal of organic compound from pharmaceutical wastewater using advanced oxidation processes
-
Chelliapan S., Sallis P.J. Removal of organic compound from pharmaceutical wastewater using advanced oxidation processes. J. Sci. Ind. Res. 2013, 72:248-254.
-
(2013)
J. Sci. Ind. Res.
, vol.72
, pp. 248-254
-
-
Chelliapan, S.1
Sallis, P.J.2
-
4
-
-
84890796482
-
New biopharmaceuticals: a review of new biologic drug approvals over the years, featuring highlights from 2010 and 2011
-
BioPharm International
-
Walsh G. New biopharmaceuticals: a review of new biologic drug approvals over the years, featuring highlights from 2010 and 2011. Process Development Forum 2012, BioPharm International. http://www.processdevelopmentforum.com/articles/new-biopharmaceuticals-a-review-of-new-biologic-drug-approvals-over-the-years-featuring-highlights-from-2010-and-2011/.
-
(2012)
Process Development Forum
-
-
Walsh, G.1
-
5
-
-
84870990715
-
Recent advances in technology supporting biopharmaceutical production from mammalian cells
-
Butler M., Meneses-Acosta A. Recent advances in technology supporting biopharmaceutical production from mammalian cells. Appl. Microbiol. Biotechnol. 2012, 96:885-894.
-
(2012)
Appl. Microbiol. Biotechnol.
, vol.96
, pp. 885-894
-
-
Butler, M.1
Meneses-Acosta, A.2
-
6
-
-
84876286207
-
Current state and recent advances in biopharmaceutical production in Escherichia coli, yeasts and mammalian cells
-
Berlec A., Strukelj B. Current state and recent advances in biopharmaceutical production in Escherichia coli, yeasts and mammalian cells. J. Ind. Microbiol. Biotechnol. 2013, 40:257-274.
-
(2013)
J. Ind. Microbiol. Biotechnol.
, vol.40
, pp. 257-274
-
-
Berlec, A.1
Strukelj, B.2
-
7
-
-
79958053952
-
Biotechnological applications of recombinant single-domain antibody fragments
-
de Marco A. Biotechnological applications of recombinant single-domain antibody fragments. Microb. Cell Fact. 2011, 10:44.
-
(2011)
Microb. Cell Fact.
, vol.10
, pp. 44
-
-
de Marco, A.1
-
8
-
-
77958518175
-
Cell culture processes for monoclonal antibody production
-
Li F., et al. Cell culture processes for monoclonal antibody production. MAbs 2010, 2:466-479.
-
(2010)
MAbs
, vol.2
, pp. 466-479
-
-
Li, F.1
-
9
-
-
84859715471
-
ScFv antibody: principles and clinical application
-
Ahmad Z.A., et al. scFv antibody: principles and clinical application. Clin. Dev. Immunol. 2012, 10.1155/2012/980250.
-
(2012)
Clin. Dev. Immunol.
-
-
Ahmad, Z.A.1
-
10
-
-
77953653252
-
Antibody fragments: hope and hype
-
Nelson A.L. Antibody fragments: hope and hype. MAbs 2010, 2:77-83.
-
(2010)
MAbs
, vol.2
, pp. 77-83
-
-
Nelson, A.L.1
-
11
-
-
77956690413
-
Biopharmaceutical benchmarks 2010
-
Walsh G. Biopharmaceutical benchmarks 2010. Nat. Biotechnol. 2010, 28:917-924.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 917-924
-
-
Walsh, G.1
-
12
-
-
84934444873
-
Expression of VHHs in Saccharomyces cerevisiae
-
Gorlani A., et al. Expression of VHHs in Saccharomyces cerevisiae. Methods Mol. Biol. 2012, 911:277-286.
-
(2012)
Methods Mol. Biol.
, vol.911
, pp. 277-286
-
-
Gorlani, A.1
-
13
-
-
84883333488
-
New and redesigned pRS plasmid shuttle vectors for genetic manipulation of Saccharomyces cerevisiae
-
Chee M.K., Haase S.B. New and redesigned pRS plasmid shuttle vectors for genetic manipulation of Saccharomyces cerevisiae. G3 (Bethesda) 2012, 2:515-526.
-
(2012)
G3 (Bethesda)
, vol.2
, pp. 515-526
-
-
Chee, M.K.1
Haase, S.B.2
-
14
-
-
80052290775
-
Application of the FLP/FRT system for conditional gene deletion in yeast Saccharomyces cerevisiae
-
Park Y.N., et al. Application of the FLP/FRT system for conditional gene deletion in yeast Saccharomyces cerevisiae. Yeast 2011, 28:673-681.
-
(2011)
Yeast
, vol.28
, pp. 673-681
-
-
Park, Y.N.1
-
15
-
-
84871990670
-
Construction of integrative plasmids suitable for genetic modification of industrial strains of Saccharomyces cerevisiae
-
Leite F.C., et al. Construction of integrative plasmids suitable for genetic modification of industrial strains of Saccharomyces cerevisiae. Plasmid 2013, 69:114-117.
-
(2013)
Plasmid
, vol.69
, pp. 114-117
-
-
Leite, F.C.1
-
16
-
-
78149328427
-
Characterization of different promoters for designing a new expression vector in Saccharomyces cerevisiae
-
Partow S., et al. Characterization of different promoters for designing a new expression vector in Saccharomyces cerevisiae. Yeast 2010, 27:955-964.
-
(2010)
Yeast
, vol.27
, pp. 955-964
-
-
Partow, S.1
-
17
-
-
56949088585
-
Reconstruction of a bacterial isoprenoid biosynthetic pathway in Saccharomyces cerevisiae
-
Maury J., et al. Reconstruction of a bacterial isoprenoid biosynthetic pathway in Saccharomyces cerevisiae. FEBS Lett. 2008, 582:4032-4038.
-
(2008)
FEBS Lett.
, vol.582
, pp. 4032-4038
-
-
Maury, J.1
-
18
-
-
0142232284
-
The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi
-
Joosten V., et al. The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi. Microb. Cell Fact. 2003, 2:1.
-
(2003)
Microb. Cell Fact.
, vol.2
, pp. 1
-
-
Joosten, V.1
-
19
-
-
24044505375
-
Analysis of unfolded protein response during single-chain antibody expression in Saccharomyces cerevisiae reveals different roles for BiP and PDI in folding
-
Xu P., et al. Analysis of unfolded protein response during single-chain antibody expression in Saccharomyces cerevisiae reveals different roles for BiP and PDI in folding. Metab. Eng. 2005, 7:269-279.
-
(2005)
Metab. Eng.
, vol.7
, pp. 269-279
-
-
Xu, P.1
-
20
-
-
84862781268
-
Engineering of vesicle trafficking improves heterologous protein secretion in Saccharomyces cerevisiae
-
Hou J., et al. Engineering of vesicle trafficking improves heterologous protein secretion in Saccharomyces cerevisiae. Metab. Eng. 2012, 14:120-127.
-
(2012)
Metab. Eng.
, vol.14
, pp. 120-127
-
-
Hou, J.1
-
21
-
-
74149090384
-
Enhanced protein secretion from multiprotease-deficient fission yeast by modification of its vacuolar protein sorting pathway
-
Idiris A., et al. Enhanced protein secretion from multiprotease-deficient fission yeast by modification of its vacuolar protein sorting pathway. Appl. Microbiol. Biotechnol. 2010, 85:667-677.
-
(2010)
Appl. Microbiol. Biotechnol.
, vol.85
, pp. 667-677
-
-
Idiris, A.1
-
22
-
-
84876676018
-
Heat shock response improves heterologous protein secretion in Saccharomyces cerevisiae
-
Hou J., et al. Heat shock response improves heterologous protein secretion in Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 2013, 97:3559-3568.
-
(2013)
Appl. Microbiol. Biotechnol.
, vol.97
, pp. 3559-3568
-
-
Hou, J.1
-
23
-
-
77954583237
-
Increasing cell biomass in Saccharomyces cerevisiae increases recombinant protein yield: the use of a respiratory strain as a microbial cell factory
-
Ferndahl C., et al. Increasing cell biomass in Saccharomyces cerevisiae increases recombinant protein yield: the use of a respiratory strain as a microbial cell factory. Microb. Cell Fact. 2010, 9:47.
-
(2010)
Microb. Cell Fact.
, vol.9
, pp. 47
-
-
Ferndahl, C.1
-
24
-
-
36149001292
-
Glycosylation engineering in yeast: the advent of fully humanized yeast
-
Hamilton S.R., Gerngross T.U. Glycosylation engineering in yeast: the advent of fully humanized yeast. Curr. Opin. Biotechnol. 2007, 18:387-392.
-
(2007)
Curr. Opin. Biotechnol.
, vol.18
, pp. 387-392
-
-
Hamilton, S.R.1
Gerngross, T.U.2
-
25
-
-
0032500528
-
Production of human compatible high mannose-type (Man5GlcNAc2) sugar chains in Saccharomyces cerevisiae
-
Chiba Y., et al. Production of human compatible high mannose-type (Man5GlcNAc2) sugar chains in Saccharomyces cerevisiae. J. Biol. Chem. 1998, 273:26298-26304.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 26298-26304
-
-
Chiba, Y.1
-
26
-
-
84890794199
-
-
Diversa Corporation (2006) GRAS notification concerning BD16449 - phospholipase C enzyme preparation from Pichia pastoris
-
Mattia, A. Diversa Corporation (2006) GRAS notification concerning BD16449 - phospholipase C enzyme preparation from Pichia pastoris, http://www.accessdata.fda.gov/scripts/fcn/gras_notices/grn000204.pdf.
-
-
-
Mattia, A.1
-
27
-
-
84863090270
-
Deletion of the Pichia pastoris KU70 homologue facilitates platform strain generation for gene expression and synthetic biology
-
Naatsaari L., et al. Deletion of the Pichia pastoris KU70 homologue facilitates platform strain generation for gene expression and synthetic biology. PLoS ONE 2012, 7:e39720.
-
(2012)
PLoS ONE
, vol.7
-
-
Naatsaari, L.1
-
28
-
-
84856790732
-
Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway
-
Krainer F.W., et al. Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway. Microb. Cell Fact. 2012, 11:22.
-
(2012)
Microb. Cell Fact.
, vol.11
, pp. 22
-
-
Krainer, F.W.1
-
29
-
-
84872686644
-
Repressible promoters - a novel tool to generate conditional mutants in Pichia pastoris
-
Delic M., et al. Repressible promoters - a novel tool to generate conditional mutants in Pichia pastoris. Microb. Cell Fact. 2013, 12:6.
-
(2013)
Microb. Cell Fact.
, vol.12
, pp. 6
-
-
Delic, M.1
-
30
-
-
77958498881
-
Variable production windows for porcine trypsinogen employing synthetic inducible promoter variants in Pichia pastoris
-
Ruth C., et al. Variable production windows for porcine trypsinogen employing synthetic inducible promoter variants in Pichia pastoris. Syst. Synth. Biol. 2010, 4:181-191.
-
(2010)
Syst. Synth. Biol.
, vol.4
, pp. 181-191
-
-
Ruth, C.1
-
31
-
-
67149116767
-
Genome sequence of the recombinant protein production host Pichia pastoris
-
De Schutter K., et al. Genome sequence of the recombinant protein production host Pichia pastoris. Nat. Biotechnol. 2009, 27:561-566.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 561-566
-
-
De Schutter, K.1
-
32
-
-
70449699931
-
Open access to sequence: browsing the Pichia pastoris genome
-
Mattanovich D., et al. Open access to sequence: browsing the Pichia pastoris genome. Microb. Cell Fact. 2009, 8:53.
-
(2009)
Microb. Cell Fact.
, vol.8
, pp. 53
-
-
Mattanovich, D.1
-
33
-
-
77954743150
-
Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production
-
Sohn S.B., et al. Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production. Biotechnol. J. 2010, 5:705-715.
-
(2010)
Biotechnol. J.
, vol.5
, pp. 705-715
-
-
Sohn, S.B.1
-
34
-
-
33644976621
-
Enhancement of protein secretion in Pichia pastoris by overexpression of protein disulfide isomerase
-
Inan M., et al. Enhancement of protein secretion in Pichia pastoris by overexpression of protein disulfide isomerase. Biotechnol. Bioeng. 2006, 93:771-778.
-
(2006)
Biotechnol. Bioeng.
, vol.93
, pp. 771-778
-
-
Inan, M.1
-
35
-
-
0032946129
-
Disruption of the KEX1 gene in Pichia pastoris allows expression of full-length murine and human endostatin
-
Boehm T., et al. Disruption of the KEX1 gene in Pichia pastoris allows expression of full-length murine and human endostatin. Yeast 1999, 15:563-572.
-
(1999)
Yeast
, vol.15
, pp. 563-572
-
-
Boehm, T.1
-
36
-
-
80155179403
-
Protein trafficking, ergosterol biosynthesis and membrane physics impact recombinant protein secretion in Pichia pastoris
-
Baumann K., et al. Protein trafficking, ergosterol biosynthesis and membrane physics impact recombinant protein secretion in Pichia pastoris. Microb. Cell Fact. 2011, 10:93.
-
(2011)
Microb. Cell Fact.
, vol.10
, pp. 93
-
-
Baumann, K.1
-
37
-
-
0035723839
-
Modeling of growth and energy metabolism of Pichia pastoris producing a fusion protein
-
Jahic M., et al. Modeling of growth and energy metabolism of Pichia pastoris producing a fusion protein. Bioprocess Biosyst. Eng. 2002, 24:385-393.
-
(2002)
Bioprocess Biosyst. Eng.
, vol.24
, pp. 385-393
-
-
Jahic, M.1
-
38
-
-
0035921173
-
Analysis of single-chain antibody production in Pichia pastoris using on-line methanol control in fed-batch and mixed-feed fermentations
-
Hellwig S., et al. Analysis of single-chain antibody production in Pichia pastoris using on-line methanol control in fed-batch and mixed-feed fermentations. Biotechnol. Bioeng. 2001, 74:344-352.
-
(2001)
Biotechnol. Bioeng.
, vol.74
, pp. 344-352
-
-
Hellwig, S.1
-
39
-
-
84862219036
-
A dynamic fed batch strategy for a Pichia pastoris mixed feed system to increase process understanding
-
Zalai D., et al. A dynamic fed batch strategy for a Pichia pastoris mixed feed system to increase process understanding. Biotechnol. Prog. 2012, 28:878-886.
-
(2012)
Biotechnol. Prog.
, vol.28
, pp. 878-886
-
-
Zalai, D.1
-
40
-
-
79951927089
-
Enhancing the protein production levels in Escherichia coli with a strong promoter
-
Tegel H., et al. Enhancing the protein production levels in Escherichia coli with a strong promoter. FEBS J. 2011, 278:729-739.
-
(2011)
FEBS J.
, vol.278
, pp. 729-739
-
-
Tegel, H.1
-
41
-
-
77449109660
-
Plasmid-free T7-based Escherichia coli expression systems
-
Striedner G., et al. Plasmid-free T7-based Escherichia coli expression systems. Biotechnol. Bioeng. 2010, 105:786-794.
-
(2010)
Biotechnol. Bioeng.
, vol.105
, pp. 786-794
-
-
Striedner, G.1
-
42
-
-
77953923884
-
Marker-free plasmids for gene therapeutic applications -Lack of antibiotic resistance gene substantially improves the manufacturing process
-
Mairhofer J., et al. Marker-free plasmids for gene therapeutic applications -Lack of antibiotic resistance gene substantially improves the manufacturing process. J. Biotechnol. 2010, 146:130-137.
-
(2010)
J. Biotechnol.
, vol.146
, pp. 130-137
-
-
Mairhofer, J.1
-
43
-
-
84879564246
-
Comparison of the cytoplasmic and periplasmic production of reteplase in Escherichia coli
-
Khodabakhsh F., et al. Comparison of the cytoplasmic and periplasmic production of reteplase in Escherichia coli. Prep. Biochem. Biotechnol. 2013, 43:613-623.
-
(2013)
Prep. Biochem. Biotechnol.
, vol.43
, pp. 613-623
-
-
Khodabakhsh, F.1
-
44
-
-
79953307855
-
Effects of cytoplasmic and periplasmic chaperones on secretory production of single-chain Fv antibody in Escherichia coli
-
Sonoda H., et al. Effects of cytoplasmic and periplasmic chaperones on secretory production of single-chain Fv antibody in Escherichia coli. J. Biosci. Bioeng. 2011, 111:465-470.
-
(2011)
J. Biosci. Bioeng.
, vol.111
, pp. 465-470
-
-
Sonoda, H.1
-
45
-
-
73849092886
-
Protein transport across and into cell membranes in bacteria and archaea
-
Yuan J.J., et al. Protein transport across and into cell membranes in bacteria and archaea. Cell. Mol. Life Sci. 2010, 67:179-199.
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 179-199
-
-
Yuan, J.J.1
-
46
-
-
84880046031
-
Enhancement of antibody fragment secretion into the Escherichia coli periplasm by co-expression with the peptidyl prolyl isomerase, FkpA, in the cytoplasm
-
Levy R., et al. Enhancement of antibody fragment secretion into the Escherichia coli periplasm by co-expression with the peptidyl prolyl isomerase, FkpA, in the cytoplasm. J. Immunol. Methods 2013, 394:10-21.
-
(2013)
J. Immunol. Methods
, vol.394
, pp. 10-21
-
-
Levy, R.1
-
47
-
-
84863303532
-
Industrial production of recombinant therapeutics in Escherichia coli and its recent advancements
-
Huang C.J., et al. Industrial production of recombinant therapeutics in Escherichia coli and its recent advancements. J. Ind. Microbiol. Biotechnol. 2012, 39:383-399.
-
(2012)
J. Ind. Microbiol. Biotechnol.
, vol.39
, pp. 383-399
-
-
Huang, C.J.1
-
48
-
-
84878083429
-
Production of antibody fragment (Fab) throughout Escherichia coli fed-batch fermentation process: changes in titre, location and form of product
-
Jalalirad R. Production of antibody fragment (Fab) throughout Escherichia coli fed-batch fermentation process: changes in titre, location and form of product. Electron. J. Biotechnol. 2013, 16. 10.2225/vol16-issue3-fulltext-15.
-
(2013)
Electron. J. Biotechnol.
, vol.16
-
-
Jalalirad, R.1
-
49
-
-
84855905968
-
Metabolic engineering for acetate control in large scale fermentation
-
Tao Y., et al. Metabolic engineering for acetate control in large scale fermentation. Methods Mol. Biol. 2012, 834:283-303.
-
(2012)
Methods Mol. Biol.
, vol.834
, pp. 283-303
-
-
Tao, Y.1
-
50
-
-
39549119605
-
Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: an alternative to fed-batch cultures
-
Lara A.R., et al. Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: an alternative to fed-batch cultures. Biotechnol. Bioeng. 2008, 99:893-901.
-
(2008)
Biotechnol. Bioeng.
, vol.99
, pp. 893-901
-
-
Lara, A.R.1
-
51
-
-
84877803588
-
Soft sensor assisted dynamic bioprocess control: efficient tools for bioprocess development
-
Sagmeister P., et al. Soft sensor assisted dynamic bioprocess control: efficient tools for bioprocess development. Chem. Eng. Sci. 2013, 96:190-198.
-
(2013)
Chem. Eng. Sci.
, vol.96
, pp. 190-198
-
-
Sagmeister, P.1
-
52
-
-
83555177325
-
Effect of post-induction substrate oscillation on recombinant alkaline phosphatase production expressed in Escherichia coli
-
Jazini M., Herwig C. Effect of post-induction substrate oscillation on recombinant alkaline phosphatase production expressed in Escherichia coli. J. Biosci. Bioeng. 2011, 112:606-610.
-
(2011)
J. Biosci. Bioeng.
, vol.112
, pp. 606-610
-
-
Jazini, M.1
Herwig, C.2
-
53
-
-
84873284678
-
Model-based analysis on the extractability of information from data in dynamic fed-batch experiments
-
Wechselberger P., et al. Model-based analysis on the extractability of information from data in dynamic fed-batch experiments. Biotechnol. Prog. 2013, 29:285-296.
-
(2013)
Biotechnol. Prog.
, vol.29
, pp. 285-296
-
-
Wechselberger, P.1
-
54
-
-
79551485538
-
Production of secretory and extracellular N-linked glycoproteins in Escherichia coli
-
Fisher A.C., et al. Production of secretory and extracellular N-linked glycoproteins in Escherichia coli. Appl. Environ. Microbiol. 2011, 77:871-881.
-
(2011)
Appl. Environ. Microbiol.
, vol.77
, pp. 871-881
-
-
Fisher, A.C.1
-
55
-
-
79952783025
-
N-Linked glycosylation of antibody fragments in Escherichia coli
-
Lizak C., et al. N-Linked glycosylation of antibody fragments in Escherichia coli. Bioconjug. Chem. 2011, 22:488-496.
-
(2011)
Bioconjug. Chem.
, vol.22
, pp. 488-496
-
-
Lizak, C.1
-
56
-
-
77952950585
-
Optimization of chemically defined cell culture media-replacing fetal bovine serum in mammalian in vitro methods
-
van der Valk J., et al. Optimization of chemically defined cell culture media-replacing fetal bovine serum in mammalian in vitro methods. Toxicol. In Vitro 2010, 24:1053-1063.
-
(2010)
Toxicol. In Vitro
, vol.24
, pp. 1053-1063
-
-
van der Valk, J.1
-
57
-
-
79952573871
-
Proteomic understanding of intracellular responses of recombinant Chinese hamster ovary cells cultivated in serum-free medium supplemented with hydrolysates
-
Kim J.Y., et al. Proteomic understanding of intracellular responses of recombinant Chinese hamster ovary cells cultivated in serum-free medium supplemented with hydrolysates. Appl. Microbiol. Biotechnol. 2011, 89:1917-1928.
-
(2011)
Appl. Microbiol. Biotechnol.
, vol.89
, pp. 1917-1928
-
-
Kim, J.Y.1
-
58
-
-
25444509538
-
Production of recombinant humanized anti-HBsAg Fab fragment from Pichia pastoris by fermentation
-
Ning D., et al. Production of recombinant humanized anti-HBsAg Fab fragment from Pichia pastoris by fermentation. J. Biochem. Mol. Biol. 2005, 38:294-299.
-
(2005)
J. Biochem. Mol. Biol.
, vol.38
, pp. 294-299
-
-
Ning, D.1
-
59
-
-
13444262282
-
The humanization of N-glycosylation pathways in yeast
-
Wildt S., Gerngross T.U. The humanization of N-glycosylation pathways in yeast. Nat. Rev. Microbiol. 2005, 3:119-128.
-
(2005)
Nat. Rev. Microbiol.
, vol.3
, pp. 119-128
-
-
Wildt, S.1
Gerngross, T.U.2
-
60
-
-
44349164573
-
Identification of a new family of genes involved in beta-1,2-mannosylation of glycans in Pichia pastoris and Candida albicans
-
Mille C., et al. Identification of a new family of genes involved in beta-1,2-mannosylation of glycans in Pichia pastoris and Candida albicans. J. Biol. Chem. 2008, 283:9724-9736.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 9724-9736
-
-
Mille, C.1
-
61
-
-
14744299579
-
Recent advances in the expression of foreign genes in Pichia pastoris
-
Cregg J.M., et al. Recent advances in the expression of foreign genes in Pichia pastoris. Biotechnology 1993, 11:905-910.
-
(1993)
Biotechnology
, vol.11
, pp. 905-910
-
-
Cregg, J.M.1
-
62
-
-
0038753800
-
Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichia pastoris
-
Choi B.K., et al. Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichia pastoris. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:5022-5027.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 5022-5027
-
-
Choi, B.K.1
-
63
-
-
79952048840
-
A combinatorial genetic library approach to target heterologous glycosylation enzymes to the endoplasmic reticulum or the Golgi apparatus of Pichia pastoris
-
Nett J.H., et al. A combinatorial genetic library approach to target heterologous glycosylation enzymes to the endoplasmic reticulum or the Golgi apparatus of Pichia pastoris. Yeast 2011, 28:237-252.
-
(2011)
Yeast
, vol.28
, pp. 237-252
-
-
Nett, J.H.1
-
64
-
-
0042322600
-
Production of complex human glycoproteins in yeast
-
Hamilton S.R., et al. Production of complex human glycoproteins in yeast. Science 2003, 301:1244-1246.
-
(2003)
Science
, vol.301
, pp. 1244-1246
-
-
Hamilton, S.R.1
-
65
-
-
77649270662
-
Engineering fully human monoclonal antibodies from murine variable regions
-
Bernett M.J., et al. Engineering fully human monoclonal antibodies from murine variable regions. J. Mol. Biol. 2010, 396:1474-1490.
-
(2010)
J. Mol. Biol.
, vol.396
, pp. 1474-1490
-
-
Bernett, M.J.1
-
66
-
-
0035902922
-
Use of HDEL-tagged Trichoderma reesei mannosyl oligosaccharide 1,2-alpha-D-mannosidase for N-glycan engineering in Pichia pastoris
-
Callewaert N., et al. Use of HDEL-tagged Trichoderma reesei mannosyl oligosaccharide 1,2-alpha-D-mannosidase for N-glycan engineering in Pichia pastoris. FEBS Lett. 2001, 503:173-178.
-
(2001)
FEBS Lett.
, vol.503
, pp. 173-178
-
-
Callewaert, N.1
-
67
-
-
2942512051
-
2-PP-Dol mannosyltransferase enzyme of P. pastoris
-
2-PP-Dol mannosyltransferase enzyme of P. pastoris. Glycobiology 2004, 14:399-407.
-
(2004)
Glycobiology
, vol.14
, pp. 399-407
-
-
Davidson, R.C.1
-
68
-
-
61449242817
-
Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology
-
Jacobs P.P., et al. Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology. Nat. Protoc. 2009, 4:58-70.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 58-70
-
-
Jacobs, P.P.1
-
69
-
-
33748483846
-
Humanization of yeast to produce complex terminally sialylated glycoproteins
-
Hamilton S.R., et al. Humanization of yeast to produce complex terminally sialylated glycoproteins. Science 2006, 313:1441-1443.
-
(2006)
Science
, vol.313
, pp. 1441-1443
-
-
Hamilton, S.R.1
-
70
-
-
81855168315
-
Elimination of beta-mannose glycan structures in Pichia pastoris
-
Hopkins D., et al. Elimination of beta-mannose glycan structures in Pichia pastoris. Glycobiology 2011, 21:1616-1626.
-
(2011)
Glycobiology
, vol.21
, pp. 1616-1626
-
-
Hopkins, D.1
-
71
-
-
84864581699
-
Improvement of N-glycan site occupancy of therapeutic glycoproteins produced in Pichia pastoris
-
Choi B.K., et al. Improvement of N-glycan site occupancy of therapeutic glycoproteins produced in Pichia pastoris. Appl. Microbiol. Biotechnol. 2012, 95:671-682.
-
(2012)
Appl. Microbiol. Biotechnol.
, vol.95
, pp. 671-682
-
-
Choi, B.K.1
-
72
-
-
82955163165
-
Optimization of a glycoengineered Pichia pastoris cultivation process for commercial antibody production
-
Ye J., et al. Optimization of a glycoengineered Pichia pastoris cultivation process for commercial antibody production. Biotechnol. Prog. 2011, 27:1744-1750.
-
(2011)
Biotechnol. Prog.
, vol.27
, pp. 1744-1750
-
-
Ye, J.1
-
73
-
-
77954928400
-
Utilization of site-specific recombination for generating therapeutic protein producing cell lines
-
Campbell M., et al. Utilization of site-specific recombination for generating therapeutic protein producing cell lines. Mol. Biotechnol. 2010, 45:199-202.
-
(2010)
Mol. Biotechnol.
, vol.45
, pp. 199-202
-
-
Campbell, M.1
-
74
-
-
77951552865
-
An accumulative site-specific gene integration system using Cre recombinase-mediated cassette exchange
-
Kameyama Y., et al. An accumulative site-specific gene integration system using Cre recombinase-mediated cassette exchange. Biotechnol. Bioeng. 2010, 105:1106-1114.
-
(2010)
Biotechnol. Bioeng.
, vol.105
, pp. 1106-1114
-
-
Kameyama, Y.1
-
75
-
-
84876959581
-
Advances in mammalian cell line development technologies for recombinant protein production
-
Lai T., et al. Advances in mammalian cell line development technologies for recombinant protein production. Pharmaceuticals 2013, 6:579-603.
-
(2013)
Pharmaceuticals
, vol.6
, pp. 579-603
-
-
Lai, T.1
-
76
-
-
77950461287
-
Evaluation of a combinatorial cell engineering approach to overcome apoptotic effects in XBP-1(s) expressing cells
-
Becker E., et al. Evaluation of a combinatorial cell engineering approach to overcome apoptotic effects in XBP-1(s) expressing cells. J. Biotechnol. 2010, 146:198-206.
-
(2010)
J. Biotechnol.
, vol.146
, pp. 198-206
-
-
Becker, E.1
-
77
-
-
84862289031
-
Intracellular interactome of secreted antibody Fab fragment in Pichia pastoris reveals its routes of secretion and degradation
-
Pfeffer M., et al. Intracellular interactome of secreted antibody Fab fragment in Pichia pastoris reveals its routes of secretion and degradation. Appl. Microbiol. Biotechnol. 2012, 93:2503-2512.
-
(2012)
Appl. Microbiol. Biotechnol.
, vol.93
, pp. 2503-2512
-
-
Pfeffer, M.1
-
78
-
-
84875579379
-
The effect of alpha-mating factor secretion signal mutations on recombinant protein expression in Pichia pastoris
-
Lin-Cereghino G.P., et al. The effect of alpha-mating factor secretion signal mutations on recombinant protein expression in Pichia pastoris. Gene 2013, 519:311-317.
-
(2013)
Gene
, vol.519
, pp. 311-317
-
-
Lin-Cereghino, G.P.1
-
79
-
-
79952456491
-
An economic comparison of three cell culture techniques
-
Lim S. An economic comparison of three cell culture techniques. BioPharm. Int. 2011, 24:54-60.
-
(2011)
BioPharm. Int.
, vol.24
, pp. 54-60
-
-
Lim, S.1
-
80
-
-
80054905919
-
A fast approach to determine a fed batch feeding profile for recombinant Pichia pastoris strains
-
Dietzsch C., et al. A fast approach to determine a fed batch feeding profile for recombinant Pichia pastoris strains. Microb. Cell Fact. 2011, 10:85.
-
(2011)
Microb. Cell Fact.
, vol.10
, pp. 85
-
-
Dietzsch, C.1
|