-
1
-
-
64349107630
-
Development trends for therapeutic antibody fragments
-
Nelson AL, Reichert JM. Development trends for therapeutic antibody fragments. Nat Biotechnol 2009; 27:331-7.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 331-337
-
-
Nelson, A.L.1
Reichert, J.M.2
-
2
-
-
69949182414
-
-
Pappas DA, Bathon JM, Hanicq D, Yasothan U, Kirkpatrick P. Golimumab. Nat Rev Drug Discov 2009; 8:695-6.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 695-696
-
-
Pappas, D.A.1
Bathon, J.M.2
Hanicq, D.3
Yasothan, U.4
Kirkpatrick, P.5
Golimumab6
-
3
-
-
0026684815
-
Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms
-
Yokota T, Milenic DE, Whitlow M, Schlom J. Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res 1992; 52:3402-8.
-
(1992)
Cancer Res
, vol.52
, pp. 3402-3408
-
-
Yokota, T.1
Milenic, D.E.2
Whitlow, M.3
Schlom, J.4
-
4
-
-
0025014962
-
Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors
-
Jain RK. Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors. Cancer Res 1990; 50:814-9.
-
(1990)
Cancer Res
, vol.50
, pp. 814-819
-
-
Jain, R.K.1
-
5
-
-
0026772358
-
Comparative stabilities in vitro and in vivo of a recombinant mouse antibody FvCys fragment and a bisFvCys conjugate
-
Cumber AJ, Ward ES, Winter G, Parnell GD, Wawrzynczak EJ. Comparative stabilities in vitro and in vivo of a recombinant mouse antibody FvCys fragment and a bisFvCys conjugate. J Immunol 1992; 149:120-6.
-
(1992)
J Immunol
, vol.149
, pp. 120-126
-
-
Cumber, A.J.1
Ward, E.S.2
Winter, G.3
Parnell, G.D.4
Wawrzynczak, E.J.5
-
6
-
-
48149104295
-
Anti-serum albumin domain antibodies for extending the half-lives of short lived drugs
-
Holt LJ, Basran A, Jones K, Chorlton J, Jespers LS, Brewis ND, Tomlinson IM. Anti-serum albumin domain antibodies for extending the half-lives of short lived drugs. Protein Eng Des Sel 2008; 21:283-8.
-
(2008)
Protein Eng Des Sel
, vol.21
, pp. 283-288
-
-
Holt, L.J.1
Basran, A.2
Jones, K.3
Chorlton, J.4
Jespers, L.S.5
Brewis, N.D.6
Tomlinson, I.M.7
-
7
-
-
52749092565
-
PEGylation: An approach for drug delivery. A review
-
Jain A, Jain SK. PEGylation: an approach for drug delivery. A review. Crit Rev Ther Drug Carrier Syst 2008; 25:403-47.
-
(2008)
Crit Rev Ther Drug Carrier Syst
, vol.25
, pp. 403-447
-
-
Jain, A.1
Jain, S.K.2
-
9
-
-
0024293979
-
Single-chain antigenbinding proteins
-
Bird RE, Hardman KD, Jacobson JW, Johnson S, Kaufman BM, Lee SM, et al. Single-chain antigenbinding proteins. Science 1988; 242:423-6.
-
(1988)
Science
, vol.242
, pp. 423-426
-
-
Bird, R.E.1
Hardman, K.D.2
Jacobson, J.W.3
Johnson, S.4
Kaufman, B.M.5
Lee, S.M.6
-
10
-
-
0028140247
-
Construction, expression and activity of a bivalent bispecific single-chain antibody
-
Mallender WD, Voss EW Jr. Construction, expression and activity of a bivalent bispecific single-chain antibody. J Biol Chem 1994; 269:199-206.
-
(1994)
J Biol Chem
, vol.269
, pp. 199-206
-
-
Mallender, W.D.1
Voss Jr., E.W.2
-
11
-
-
0029609864
-
Correct disulfide pairing and efficient refolding of detergentsolubilized single-chain Fv proteins from bacterial inclusion bodies
-
Kurucz I, Titus JA, Jost CR, Segal DM. Correct disulfide pairing and efficient refolding of detergentsolubilized single-chain Fv proteins from bacterial inclusion bodies. Mol Immunol 1995; 32:1443-52.
-
(1995)
Mol Immunol
, vol.32
, pp. 1443-1452
-
-
Kurucz, I.1
Titus, J.A.2
Jost, C.R.3
Segal, D.M.4
-
12
-
-
0028236196
-
Single-chain mono- and bispecific antibody derivatives with novel biological properties and antitumour activity from a COS cell transient expression system
-
Hayden MS, Linsley PS, Gayle MA, Bajorath J, Brady WA, Norris NA, et al. Single-chain mono- and bispecific antibody derivatives with novel biological properties and antitumour activity from a COS cell transient expression system. Ther Immunol 1994; 1:3-15.
-
(1994)
Ther Immunol
, vol.1
, pp. 3-15
-
-
Hayden, M.S.1
Linsley, P.S.2
Gayle, M.A.3
Bajorath, J.4
Brady, W.A.5
Norris, N.A.6
-
13
-
-
77951523463
-
-
Chames P, Baty D. Bispecific antibodies for cancer therapy: the light at the end of the tunnel? mAbs 2009; 1:539-47.
-
Chames P, Baty D. Bispecific antibodies for cancer therapy: the light at the end of the tunnel? mAbs 2009; 1:539-47.
-
-
-
-
14
-
-
0037143806
-
Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody
-
Dreier T, Lorenczewski G, Brandl C, Hoffmann P, Syring U, Hanakam F, et al. Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody. Int J Cancer 2002; 100:690-7.
-
(2002)
Int J Cancer
, vol.100
, pp. 690-697
-
-
Dreier, T.1
Lorenczewski, G.2
Brandl, C.3
Hoffmann, P.4
Syring, U.5
Hanakam, F.6
-
15
-
-
28944434529
-
Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on MHC class I-negative tumor cells
-
Offner S, Hofmeister R, Romaniuk A, Kufer P, Baeuerle PA. Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on MHC class I-negative tumor cells. Mol Immunol 2006; 43:763-71.
-
(2006)
Mol Immunol
, vol.43
, pp. 763-771
-
-
Offner, S.1
Hofmeister, R.2
Romaniuk, A.3
Kufer, P.4
Baeuerle, P.A.5
-
16
-
-
0029890636
-
Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts
-
Hu S, Shively L, Raubitschek A, Sherman M, Williams LE, Wong JY, et al. Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts. Cancer Res 1996; 56:3055-61.
-
(1996)
Cancer Res
, vol.56
, pp. 3055-3061
-
-
Hu, S.1
Shively, L.2
Raubitschek, A.3
Sherman, M.4
Williams, L.E.5
Wong, J.Y.6
-
17
-
-
0142080390
-
Domain antibodies: Proteins for therapy
-
Holt LJ, Herring C, Jespers LS, Woolven BP, Tomlinson IM. Domain antibodies: proteins for therapy. Trends Biotechnol 2003; 21:484-90.
-
(2003)
Trends Biotechnol
, vol.21
, pp. 484-490
-
-
Holt, L.J.1
Herring, C.2
Jespers, L.S.3
Woolven, B.P.4
Tomlinson, I.M.5
-
18
-
-
0020518331
-
Hybrid hybridomas and their use in immunohistochemistry
-
Milstein C, Cuello AC. Hybrid hybridomas and their use in immunohistochemistry. Nature 1983; 305:537-40.
-
(1983)
Nature
, vol.305
, pp. 537-540
-
-
Milstein, C.1
Cuello, A.C.2
-
19
-
-
0033178740
-
Simultaneous activation of T cells and accessory cells by a new class of intact bispecific antibody results in efficient tumor cell killing
-
Zeidler R, Reisbach G, Wollenberg B, Lang S, Chaubal S, Schmitt B, et al. Simultaneous activation of T cells and accessory cells by a new class of intact bispecific antibody results in efficient tumor cell killing. J Immunol 1999; 163:1246-52.
-
(1999)
J Immunol
, vol.163
, pp. 1246-1252
-
-
Zeidler, R.1
Reisbach, G.2
Wollenberg, B.3
Lang, S.4
Chaubal, S.5
Schmitt, B.6
-
20
-
-
34247876138
-
Development trends for monoclonal antibody cancer therapeutics
-
Reichert JM, Valge-Archer V. Development trends for monoclonal antibody cancer therapeutics. Nat Rev Drug Discov 2007; 6:349-56.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 349-356
-
-
Reichert, J.M.1
Valge-Archer, V.2
-
21
-
-
27144432842
-
Engineered antibody fragments and the rise of single domains
-
Holliger P, Hudson PJ. Engineered antibody fragments and the rise of single domains. Nat Biotechnol 2005; 23:1126-36.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1126-1136
-
-
Holliger, P.1
Hudson, P.J.2
-
22
-
-
60849128549
-
Monoclonal antibodies as innovative therapeutics
-
Reichert JM. Monoclonal antibodies as innovative therapeutics. Curr Pharm Biotechnol 2008; 9:423-30.
-
(2008)
Curr Pharm Biotechnol
, vol.9
, pp. 423-430
-
-
Reichert, J.M.1
|