메뉴 건너뛰기




Volumn 28, Issue 9, 2011, Pages 673-681

Application of the FLP/FRT system for conditional gene deletion in yeast Saccharomyces cerevisiae

Author keywords

Conditional gene deletion; Flp recombinase; FRT; Yeast

Indexed keywords

GALACTOSE; RECOMBINASE;

EID: 80052290775     PISSN: 0749503X     EISSN: 10970061     Source Type: Journal    
DOI: 10.1002/yea.1895     Document Type: Article
Times cited : (28)

References (34)
  • 1
    • 33748377124 scopus 로고    scopus 로고
    • Quantification of protein half-lives in the budding yeast proteome
    • Belle A, Tanay A, Bitincka L, et al. 2006. Quantification of protein half-lives in the budding yeast proteome. Proc Natl Acad Sci USA 103: 13004-13009.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13004-13009
    • Belle, A.1    Tanay, A.2    Bitincka, L.3
  • 2
    • 0032519306 scopus 로고    scopus 로고
    • An activator/repressor dual system allows tight tetracycline-regulated gene expression in budding yeast
    • Belli G, Gari E, Piedrafita L, et al. 1998. An activator/repressor dual system allows tight tetracycline-regulated gene expression in budding yeast. Nucleic Acids Res 26: 942-947.
    • (1998) Nucleic Acids Res , vol.26 , pp. 942-947
    • Belli, G.1    Gari, E.2    Piedrafita, L.3
  • 4
    • 0020132004 scopus 로고
    • Recombination within the yeast plasmid 2 μ circle is site-specific
    • Broach JR, Guarascio VR, Jayaram M. 1982. Recombination within the yeast plasmid 2 μ circle is site-specific. Cell 29: 227-234.
    • (1982) Cell , vol.29 , pp. 227-234
    • Broach, J.R.1    Guarascio, V.R.2    Jayaram, M.3
  • 6
    • 0020526141 scopus 로고
    • The FLP protein of the yeast 2 μ plasmid: expression of a eukaryotic genetic recombination system in Escherichia coli
    • Cox MM. 1983. The FLP protein of the yeast 2 μ plasmid: expression of a eukaryotic genetic recombination system in Escherichia coli. Proc Natl Acad Sci USA 80: 4223-4227.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 4223-4227
    • Cox, M.M.1
  • 7
    • 0037138377 scopus 로고    scopus 로고
    • Regulated expression of proteins in yeast using the MAL61-62 promoter and a mating scheme to increase dynamic range
    • Finley RL Jr, Zhang H, Zhong J, Stanyon CA. 2002. Regulated expression of proteins in yeast using the MAL61-62 promoter and a mating scheme to increase dynamic range. Gene 285: 49-57.
    • (2002) Gene , vol.285 , pp. 49-57
    • Finley Jr, R.L.1    Zhang, H.2    Zhong, J.3    Stanyon, C.A.4
  • 8
    • 0025073497 scopus 로고
    • Two systems of glucose repression of the GAL1 promoter in Saccharomyces cerevisiae
    • Flick JS, Johnston M. 1990. Two systems of glucose repression of the GAL1 promoter in Saccharomyces cerevisiae. Mol Cell Biol 10: 4757-4769.
    • (1990) Mol Cell Biol , vol.10 , pp. 4757-4769
    • Flick, J.S.1    Johnston, M.2
  • 9
    • 0024378286 scopus 로고
    • The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome
    • Golic KG, Lindquist S. 1989. The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome. Cell 59: 499-509.
    • (1989) Cell , vol.59 , pp. 499-509
    • Golic, K.G.1    Lindquist, S.2
  • 10
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen M, Bujard H. 1992. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89: 5547-5551.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 11
    • 34547607675 scopus 로고    scopus 로고
    • A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae
    • Grilly C, Stricker J, Pang WL, et al. 2007. A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae. Mol Syst Biol 3: 127.
    • (2007) Mol Syst Biol , vol.3 , pp. 127
    • Grilly, C.1    Stricker, J.2    Pang, W.L.3
  • 12
    • 0022198041 scopus 로고
    • The FLP recombinase of the Saccharomyces cerevisiae 2 μ plasmid attaches covalently to DNA via a phosphotyrosyl linkage
    • Gronostajski RM, Sadowski PD. 1985. The FLP recombinase of the Saccharomyces cerevisiae 2 μ plasmid attaches covalently to DNA via a phosphotyrosyl linkage. Mol Cell Biol 5: 3274-3279.
    • (1985) Mol Cell Biol , vol.5 , pp. 3274-3279
    • Gronostajski, R.M.1    Sadowski, P.D.2
  • 13
    • 0020359805 scopus 로고
    • A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site
    • Guarente L, Yocum RR, Gifford P. 1982. A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site. Proc Natl Acad Sci USA 79: 7410-4.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 7410-7414
    • Guarente, L.1    Yocum, R.R.2    Gifford, P.3
  • 14
    • 0029994841 scopus 로고    scopus 로고
    • A new efficient gene disruption cassette for repeated use in budding yeast
    • Guldener U, Heck S, Fielder T, et al. 1996. A new efficient gene disruption cassette for repeated use in budding yeast. Nucleic Acids Res 24: 2519-2524.
    • (1996) Nucleic Acids Res , vol.24 , pp. 2519-2524
    • Guldener, U.1    Heck, S.2    Fielder, T.3
  • 15
    • 0028030082 scopus 로고
    • Mechanisms underlying expression of Tn10 encoded tetracycline resistance
    • Hillen W, Berens C. 1994. Mechanisms underlying expression of Tn10 encoded tetracycline resistance. Annu Rev Microbiol 48: 345-369.
    • (1994) Annu Rev Microbiol , vol.48 , pp. 345-369
    • Hillen, W.1    Berens, C.2
  • 16
    • 1942518319 scopus 로고    scopus 로고
    • +] prion is impaired by factors that regulate Hsp70 substrate binding
    • +] prion is impaired by factors that regulate Hsp70 substrate binding. Mol Cell Biol 24: 3928-3937.
    • (2004) Mol Cell Biol , vol.24 , pp. 3928-3937
    • Jones, G.1    Song, Y.2    Chung, S.3    Masison, D.C.4
  • 17
    • 0034974996 scopus 로고    scopus 로고
    • Guanidine hydrochloride inhibits Hsp104 activity in vivo: a possible explanation for its effect in curing yeast prions
    • Jung G, Masison DC. 2001. Guanidine hydrochloride inhibits Hsp104 activity in vivo: a possible explanation for its effect in curing yeast prions. Curr Microbiol 43: 7-10.
    • (2001) Curr Microbiol , vol.43 , pp. 7-10
    • Jung, G.1    Masison, D.C.2
  • 18
    • 38549126635 scopus 로고    scopus 로고
    • Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter
    • Karpova TS, Kim MJ, Spriet C, et al. 2008. Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter. Science 319: 466-469.
    • (2008) Science , vol.319 , pp. 466-469
    • Karpova, T.S.1    Kim, M.J.2    Spriet, C.3
  • 19
    • 77954720757 scopus 로고    scopus 로고
    • Application of the Saccharomyces cerevisiae FLP/FRT recombination system in filamentous fungi for marker recycling and construction of knockout strains devoid of heterologous genes
    • Kopke K, Hoff B, Kuck U. 2010. Application of the Saccharomyces cerevisiae FLP/FRT recombination system in filamentous fungi for marker recycling and construction of knockout strains devoid of heterologous genes. Appl Environ Microbiol 76: 4664-4674.
    • (2010) Appl Environ Microbiol , vol.76 , pp. 4664-4674
    • Kopke, K.1    Hoff, B.2    Kuck, U.3
  • 20
    • 0036338128 scopus 로고    scopus 로고
    • Efficient Cre-loxP-induced mitotic recombination in mouse embryonic stem cells
    • Liu P, Jenkins NA, Copeland NG. 2002. Efficient Cre-loxP-induced mitotic recombination in mouse embryonic stem cells. Nat Genet 30: 66-72.
    • (2002) Nat Genet , vol.30 , pp. 66-72
    • Liu, P.1    Jenkins, N.A.2    Copeland, N.G.3
  • 21
    • 0028219192 scopus 로고
    • Functional expression of the yeast FLP/FRT site-specific recombination system in Nicotiana tabacum
    • Lloyd AM, Davis RW. 1994. Functional expression of the yeast FLP/FRT site-specific recombination system in Nicotiana tabacum. Mol Gen Genet 242: 653-657.
    • (1994) Mol Gen Genet , vol.242 , pp. 653-657
    • Lloyd, A.M.1    Davis, R.W.2
  • 23
    • 0028586017 scopus 로고
    • Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression
    • Mumberg D, Muller R, Funk M. 1994. Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression. Nucleic Acids Res 22: 5767-5768.
    • (1994) Nucleic Acids Res , vol.22 , pp. 5767-5768
    • Mumberg, D.1    Muller, R.2    Funk, M.3
  • 24
    • 0032951475 scopus 로고    scopus 로고
    • Antagonistic interactions between yeast chaperones Hsp104 and Hsp70 in prion curing
    • Newnam GP, Wegrzyn RD, Lindquist SL, Chernoff YO. 1999. Antagonistic interactions between yeast chaperones Hsp104 and Hsp70 in prion curing. Mol Cell Biol 19: 1325-1333.
    • (1999) Mol Cell Biol , vol.19 , pp. 1325-1333
    • Newnam, G.P.1    Wegrzyn, R.D.2    Lindquist, S.L.3    Chernoff, Y.O.4
  • 25
    • 0025847620 scopus 로고
    • Recombinase-mediated gene activation and site-specific integration in mammalian cells
    • O'Gorman S, Fox DT, Wahl GM. 1991. Recombinase-mediated gene activation and site-specific integration in mammalian cells. Science 251: 1351-1355.
    • (1991) Science , vol.251 , pp. 1351-1355
    • O'Gorman, S.1    Fox, D.T.2    Wahl, G.M.3
  • 26
    • 23844485512 scopus 로고    scopus 로고
    • Tetracycline-inducible gene expression and gene deletion in Candida albicans
    • Park YN, Morschhauser J. 2005. Tetracycline-inducible gene expression and gene deletion in Candida albicans. Eukaryot Cell 4: 1328-1342.
    • (2005) Eukaryot Cell , vol.4 , pp. 1328-1342
    • Park, Y.N.1    Morschhauser, J.2
  • 27
    • 0019958241 scopus 로고
    • Acid phosphatase polypeptides in Saccharomyces cerevisiae are encoded by a differentially regulated multigene family
    • Rogers DT, Lemire JM, Bostian KA. 1982. Acid phosphatase polypeptides in Saccharomyces cerevisiae are encoded by a differentially regulated multigene family. Proc Natl Acad Sci USA 79: 2157-2161.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 2157-2161
    • Rogers, D.T.1    Lemire, J.M.2    Bostian, K.A.3
  • 28
    • 0023352241 scopus 로고
    • Functional expression of the cre-lox site-specific recombination system in the yeast Saccharomyces cerevisiae
    • Sauer B. 1987. Functional expression of the cre-lox site-specific recombination system in the yeast Saccharomyces cerevisiae. Mol Cell Biol 7: 2087-2096.
    • (1987) Mol Cell Biol , vol.7 , pp. 2087-2096
    • Sauer, B.1
  • 29
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski RS, Hieter P. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 30
    • 0034608802 scopus 로고    scopus 로고
    • Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity
    • Urlinger S, Baron U, Thellmann M, et al. 2000. Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity. Proc Natl Acad Sci USA 97: 7963-7968.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 7963-7968
    • Urlinger, S.1    Baron, U.2    Thellmann, M.3
  • 31
    • 0345602733 scopus 로고    scopus 로고
    • PCR-based methods facilitate targeted gene manipulations and cloning procedures
    • Wendland J. 2003. PCR-based methods facilitate targeted gene manipulations and cloning procedures. Curr Genet 44: 115-123.
    • (2003) Curr Genet , vol.44 , pp. 115-123
    • Wendland, J.1
  • 33
    • 33750511727 scopus 로고    scopus 로고
    • A survey of essential gene function in the yeast cell division cycle
    • Yu L, Pena Castillo L, Mnaimneh S, et al. 2006. A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17: 4736-4747.
    • (2006) Mol Biol Cell , vol.17 , pp. 4736-4747
    • Yu, L.1    Pena Castillo, L.2    Mnaimneh, S.3
  • 34
    • 0029082452 scopus 로고
    • Cleavage-dependent ligation by the FLP recombinase. Characterization of a mutant FLP protein with an alteration in a catalytic amino acid
    • Zhu XD, Sadowski PD. 1995. Cleavage-dependent ligation by the FLP recombinase. Characterization of a mutant FLP protein with an alteration in a catalytic amino acid. J Biol Chem 270: 23044-23054.
    • (1995) J Biol Chem , vol.270 , pp. 23044-23054
    • Zhu, X.D.1    Sadowski, P.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.