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Volumn 29, Issue 1, 2013, Pages 285-296

Model-based analysis on the extractability of information from data in dynamic fed-batch experiments

Author keywords

Bioprocess model; Bioprocess optimization; Data exploitation; Dynamic experiments; Quality by design

Indexed keywords

BIOPROCESS OPTIMIZATION; BIOPROCESSES; DATA EXPLOITATION; DYNAMIC EXPERIMENT; QUALITY BY DESIGNS;

EID: 84873284678     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.1649     Document Type: Article
Times cited : (28)

References (36)
  • 1
    • 84873293689 scopus 로고    scopus 로고
    • A QbD case study: Utilizing small-scale design space knowledge to accelerate progress to large-scale process validation runs. Abstracts of Papers, 238th ACS National Meeting, Washington, DC, United States, August 16-20, 2009:BIOT-042.
    • Yang LY, Abu-Absi S, Thompson P, Andrabi M, Carone T, Mackin N, Schilling B, Shukla A. A QbD case study: Utilizing small-scale design space knowledge to accelerate progress to large-scale process validation runs. Abstracts of Papers, 238th ACS National Meeting, Washington, DC, United States, August 16-20, 2009. 2009:BIOT-042.
    • (2009)
    • Yang, L.Y.1    Abu-Absi, S.2    Thompson, P.3    Andrabi, M.4    Carone, T.5    Mackin, N.6    Schilling, B.7    Shukla, A.8
  • 2
    • 68749083515 scopus 로고    scopus 로고
    • Roadmap for implementation of quality by design (QbD) for biotechnology products
    • Rathore AS. Roadmap for implementation of quality by design (QbD) for biotechnology products. Trends Biotechnol. 2009; 27: 546-553.
    • (2009) Trends Biotechnol. , vol.27 , pp. 546-553
    • Rathore, A.S.1
  • 3
    • 84873291360 scopus 로고    scopus 로고
    • ISPE. Creating QbD/PAT Management Awareness.
    • ISPE. Creating QbD/PAT Management Awareness. www.ispe.org. 2007.
    • (2007)
  • 4
    • 84873285901 scopus 로고    scopus 로고
    • ICH. Q8, Pharmaceutical Development (R1).
    • ICH. Q8, Pharmaceutical Development (R1). www.ich.org. 2008.
    • (2008)
  • 5
    • 70350208809 scopus 로고    scopus 로고
    • Quality by design case study: an integrated multivariate approach to drug product and process development
    • Huang J, Kaul G, Cai C, Chatlapalli R, Hernandez-Abad P, Ghosh K, Nagi A. Quality by design case study: an integrated multivariate approach to drug product and process development. Int J Pharma. 2009; 382: 23-32.
    • (2009) Int J Pharma. , vol.382 , pp. 23-32
    • Huang, J.1    Kaul, G.2    Cai, C.3    Chatlapalli, R.4    Hernandez-Abad, P.5    Ghosh, K.6    Nagi, A.7
  • 6
    • 60349106410 scopus 로고    scopus 로고
    • Analysis of the Escherichia coli response to glycerol pulse in continuous, high-cell density culture using a multivariate approach
    • Guebel DV, Canovas M, Torres NV. Analysis of the Escherichia coli response to glycerol pulse in continuous, high-cell density culture using a multivariate approach. Biotechnol Bioeng. 2009; 102: 910-922.
    • (2009) Biotechnol Bioeng. , vol.102 , pp. 910-922
    • Guebel, D.V.1    Canovas, M.2    Torres, N.V.3
  • 7
    • 0036798016 scopus 로고    scopus 로고
    • Online monitoring of a bioprocess based on a multi-analyser system and multivariate statistical process modelling
    • Cimander C, Mandenius C-F. Online monitoring of a bioprocess based on a multi-analyser system and multivariate statistical process modelling. J Chem Technol Biotechnol. 2002; 77: 1157-1168.
    • (2002) J Chem Technol Biotechnol. , vol.77 , pp. 1157-1168
    • Cimander, C.1    Mandenius, C.-F.2
  • 8
    • 67349089877 scopus 로고    scopus 로고
    • Data-driven soft sensors in the process industry
    • Kadlec P, Gabrys B, Strandt S. Data-driven soft sensors in the process industry. Comput Chem Eng. 2009; 33: 795-814.
    • (2009) Comput Chem Eng. , vol.33 , pp. 795-814
    • Kadlec, P.1    Gabrys, B.2    Strandt, S.3
  • 9
    • 0033527915 scopus 로고    scopus 로고
    • Mass balance modeling of vanillin production from vanillic acid by cultures of the fungus Pycnoporus cinnabarinus in bioreactors
    • Bernard O, Bastin G, Stentelaire C, Lesage-Meessen L, Asther M. Mass balance modeling of vanillin production from vanillic acid by cultures of the fungus Pycnoporus cinnabarinus in bioreactors. Biotechnol Bioeng. 1999; 65: 558-571.
    • (1999) Biotechnol Bioeng. , vol.65 , pp. 558-571
    • Bernard, O.1    Bastin, G.2    Stentelaire, C.3    Lesage-Meessen, L.4    Asther, M.5
  • 10
    • 0022736565 scopus 로고
    • Growth of Saccharomyces cerevisiae is controlled by its limited respiratory capacity: formulation and verification of a hypothesis
    • Sonnleitner B, Kaeppeli O. Growth of Saccharomyces cerevisiae is controlled by its limited respiratory capacity: formulation and verification of a hypothesis. Biotechnol Bioeng. 1986; 28: 927-937.
    • (1986) Biotechnol Bioeng. , vol.28 , pp. 927-937
    • Sonnleitner, B.1    Kaeppeli, O.2
  • 11
    • 84859891750 scopus 로고    scopus 로고
    • Debottlenecking recombinant protein production in Bacillus megaterium under large-scale conditions-targeted precursor feeding designed from metabolomics
    • Korneli C, Bolten CJ, Godard T, Franco-Lara E, Wittmann C. Debottlenecking recombinant protein production in Bacillus megaterium under large-scale conditions-targeted precursor feeding designed from metabolomics. Biotechnol Bioeng. 2012;109:1538-1550.
    • (2012) Biotechnol Bioeng. , vol.109 , pp. 1538-1550
    • Korneli, C.1    Bolten, C.J.2    Godard, T.3    Franco-Lara, E.4    Wittmann, C.5
  • 12
    • 35748959651 scopus 로고    scopus 로고
    • Response of fluxome and metabolome to temperature-induced recombinant protein synthesis in Escherichia coli
    • Wittmann C, Weber J, Betiku E, Kroemer J, Boehm D, Rinas U. Response of fluxome and metabolome to temperature-induced recombinant protein synthesis in Escherichia coli. J. Biotechnol. 2007; 132: 375-384.
    • (2007) J. Biotechnol. , vol.132 , pp. 375-384
    • Wittmann, C.1    Weber, J.2    Betiku, E.3    Kroemer, J.4    Boehm, D.5    Rinas, U.6
  • 13
    • 84863413710 scopus 로고    scopus 로고
    • Analyzing the metabolic stress response of recombinant Escherichia coli cultures expressing human interferon-beta in high cell density fed batch cultures using time course transcriptomic data
    • Singh AB, Sharma AK, Mukherjee KJ. Analyzing the metabolic stress response of recombinant Escherichia coli cultures expressing human interferon-beta in high cell density fed batch cultures using time course transcriptomic data. Mol BioSyst. 2012; 8: 615-628.
    • (2012) Mol BioSyst. , vol.8 , pp. 615-628
    • Singh, A.B.1    Sharma, A.K.2    Mukherjee, K.J.3
  • 14
    • 43049096460 scopus 로고    scopus 로고
    • Monitoring of transcriptome and proteome profiles to investigate the cellular response of E. coli towards recombinant protein expression under defined chemostat conditions
    • Duerrschmid K, Reischer H, Schmidt-Heck W, Hrebicek T, Guthke R, Rizzi A, Bayer K. Monitoring of transcriptome and proteome profiles to investigate the cellular response of E. coli towards recombinant protein expression under defined chemostat conditions. J. Biotechnol. 2008; 135: 34-44.
    • (2008) J. Biotechnol. , vol.135 , pp. 34-44
    • Duerrschmid, K.1    Reischer, H.2    Schmidt-Heck, W.3    Hrebicek, T.4    Guthke, R.5    Rizzi, A.6    Bayer, K.7
  • 15
    • 0035813388 scopus 로고    scopus 로고
    • On-line stoichiometry and identification of metabolic state under dynamic process conditions
    • Herwig C, Marison I, Von Stockar U. On-line stoichiometry and identification of metabolic state under dynamic process conditions. Biotechnol Bioeng. 2001; 75: 345-354.
    • (2001) Biotechnol Bioeng. , vol.75 , pp. 345-354
    • Herwig, C.1    Marison, I.2    Von Stockar, U.3
  • 16
    • 84873308754 scopus 로고    scopus 로고
    • ICH. Q9, Quality risk management.
    • ICH. Q9, Quality risk management. www.ich.org. 2005.
    • (2005)
  • 17
    • 60149106150 scopus 로고    scopus 로고
    • Quality by design for biopharmaceuticals
    • Rathore AS, Winkle H. Quality by design for biopharmaceuticals. Nat Biotechnol. 2009; 27: 26-34.
    • (2009) Nat Biotechnol. , vol.27 , pp. 26-34
    • Rathore, A.S.1    Winkle, H.2
  • 18
    • 33846927258 scopus 로고    scopus 로고
    • Scale-down and parallel operation of the riboflavin production process with Bacillus subtilis
    • Knorr B, Schlieker H, Hohmann H-P, Weuster-Botz D. Scale-down and parallel operation of the riboflavin production process with Bacillus subtilis. Biochem Eng J. 2007; 33: 263-274.
    • (2007) Biochem Eng J. , vol.33 , pp. 263-274
    • Knorr, B.1    Schlieker, H.2    Hohmann, H.-P.3    Weuster-Botz, D.4
  • 19
    • 15944379153 scopus 로고    scopus 로고
    • Development, parallelization, and automation of a gas-inducing milliliter-scale bioreactor for high-throughput bioprocess design (HTBD)
    • Puskeiler R, Kaufmann K, Weuster-Botz D. Development, parallelization, and automation of a gas-inducing milliliter-scale bioreactor for high-throughput bioprocess design (HTBD). Biotechnol Bioeng. 2005; 89: 512-523.
    • (2005) Biotechnol Bioeng. , vol.89 , pp. 512-523
    • Puskeiler, R.1    Kaufmann, K.2    Weuster-Botz, D.3
  • 21
    • 33745482610 scopus 로고    scopus 로고
    • Improvement of bioprocess monitoring: development of novel concepts
    • Clementschitsch F, Bayer K. Improvement of bioprocess monitoring: development of novel concepts. Microb Cell Factories. 2006; 5: 183-196.
    • (2006) Microb Cell Factories. , vol.5 , pp. 183-196
    • Clementschitsch, F.1    Bayer, K.2
  • 23
    • 0028500729 scopus 로고
    • Linear constraint relations in biochemical reaction systems. III. Sequential application of data reconciliation for sensitive detection of systematic errors
    • van der Heijden RTJM, Romein B, Heijnen JJ, Hellinga C, Luyben KCAM. Linear constraint relations in biochemical reaction systems. III. Sequential application of data reconciliation for sensitive detection of systematic errors. Biotechnol Bioeng. 1994; 44: 781-791.
    • (1994) Biotechnol Bioeng. , vol.44 , pp. 781-791
    • van der Heijden, R.T.J.M.1    Romein, B.2    Heijnen, J.J.3    Hellinga, C.4    Luyben, K.C.A.M.5
  • 24
    • 83555177325 scopus 로고    scopus 로고
    • Effect of post-induction substrate oscillation on recombinant alkaline phosphatase production expressed in Escherichia coli
    • Jazini M, Herwig C. Effect of post-induction substrate oscillation on recombinant alkaline phosphatase production expressed in Escherichia coli. J Biosci Bioeng. 2011; 112: 606-610.
    • (2011) J Biosci Bioeng. , vol.112 , pp. 606-610
    • Jazini, M.1    Herwig, C.2
  • 26
    • 2942755215 scopus 로고    scopus 로고
    • Stress induced by recombinant protein production in Escherichia coli
    • Hoffmann F, Rinas U. Stress induced by recombinant protein production in Escherichia coli. Adv Biochem Eng/Biotechnol. 2004; 89: 73-92.
    • (2004) Adv Biochem Eng/Biotechnol. , vol.89 , pp. 73-92
    • Hoffmann, F.1    Rinas, U.2
  • 27
    • 0028764687 scopus 로고
    • Linear constraint relations in biochemical reaction systems. I. Classification of the calculability and the balanceability of conversion rates
    • van der Heijden RTJM, Romein B, Heijnen JJ, Hellinga C, Luyben KCAM. Linear constraint relations in biochemical reaction systems. I. Classification of the calculability and the balanceability of conversion rates. Biotechnol Bioeng. 1994; 43: 3-20.
    • (1994) Biotechnol Bioeng. , vol.43 , pp. 3-20
    • van der Heijden, R.T.J.M.1    Romein, B.2    Heijnen, J.J.3    Hellinga, C.4    Luyben, K.C.A.M.5
  • 28
    • 77957345665 scopus 로고    scopus 로고
    • PAT method to gather bioprocess parameters in real-time using simple input variables and first principle relationships
    • Wechselberger P, Seifert A, Herwig C. PAT method to gather bioprocess parameters in real-time using simple input variables and first principle relationships. Chem Eng Sci. 2010; 65: 5734-5746.
    • (2010) Chem Eng Sci. , vol.65 , pp. 5734-5746
    • Wechselberger, P.1    Seifert, A.2    Herwig, C.3
  • 29
    • 84856583859 scopus 로고    scopus 로고
    • Model-based analysis on the relationship of signal quality to real-time extraction of information in bioprocesses
    • Wechselberger P, Herwig C. Model-based analysis on the relationship of signal quality to real-time extraction of information in bioprocesses. Biotechnol Prog. 2012; 28: 265-275.
    • (2012) Biotechnol Prog. , vol.28 , pp. 265-275
    • Wechselberger, P.1    Herwig, C.2
  • 31
    • 0027281110 scopus 로고
    • Introduction to the dielectric estimation of cellular biomass in real time, with special emphasis on measurements at high volume fractions
    • Davey CL, Davey HM, Kell DB. Introduction to the dielectric estimation of cellular biomass in real time, with special emphasis on measurements at high volume fractions. Anal Chim Acta. 1993; 279: 155-161.
    • (1993) Anal Chim Acta. , vol.279 , pp. 155-161
    • Davey, C.L.1    Davey, H.M.2    Kell, D.B.3
  • 32
    • 0025132985 scopus 로고
    • On-line fermentation gas analysis: error analysis and application of mass spectrometry
    • Heinzle E, Oeggerli A, Dettweiler B. On-line fermentation gas analysis: error analysis and application of mass spectrometry. Anal Chim Acta. 1990; 238: 101-115.
    • (1990) Anal Chim Acta. , vol.238 , pp. 101-115
    • Heinzle, E.1    Oeggerli, A.2    Dettweiler, B.3
  • 34
    • 0017516706 scopus 로고
    • Statistical analysis of material balance of a chemical reactor
    • Madron F, Veverka V, Vanecek V. Statistical analysis of material balance of a chemical reactor. AIChE J. 1977; 23: 482-486.
    • (1977) AIChE J. , vol.23 , pp. 482-486
    • Madron, F.1    Veverka, V.2    Vanecek, V.3


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