Engineering of vesicle trafficking improves heterologous protein secretion in Saccharomyces cerevisiae

Metabolic Engineering

Volumn 14, Issue 2, 2012, Pages 120-127

  Hou, Jin ^a   Tyo, Keith ^a,b   Liu, Zihe ^a   Petranovic, Dina ^a   Nielsen, Jens ^a  

^a CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^b Northwestern University   (United States)

Author keywords

Heterologous protein secretion; Saccharomyces cerevisiae; Sec1p; Sly1p; Vesicle trafficking

Indexed keywords

AMYLASE PRODUCTION; ENDOPLASMIC RETICULUM; HETEROLOGOUS PROTEIN PRODUCTION; HETEROLOGOUS PROTEIN SECRETION; HETEROLOGOUS PROTEINS; HOST STRAIN; MEMBRANE PROCESS; OVER-EXPRESSION; PROTEIN SECRETION; PROTEIN SECRETORY PATHWAY; PROTEIN TRAFFICKING; PROTEIN-ENCODING GENES; S.CEREVISIAE; SEC1P; SLY1P; VESICLE FUSION; VESICLE TRAFFICKING; YEAST SACCHAROMYCES CEREVISIAE;

AMYLASES; CELL MEMBRANES; CYTOLOGY; GENE EXPRESSION; PHYSIOLOGY; YEAST;

PROTEINS;

AMYLASE; BETA FRUCTOFURANOSIDASE; FUNGAL PROTEIN; MUNC18 PROTEIN; PREPROINSULIN; SEC1 PROTEIN; SLY1 PROTEIN; SNARE PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CELL MEMBRANE; CELL ORGANELLE; CELL VACUOLE; COMPLEX FORMATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FUNGAL GENE; GENE OVEREXPRESSION; GOLGI COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN SECRETION; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE;

ALPHA-AMYLASES; BIOLOGICAL TRANSPORT; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; HUMANS; INSULIN; METABOLIC ENGINEERING; MUNC18 PROTEINS; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SECRETORY VESICLES; SNARE PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 84862781268     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2012.01.002     Document Type: Article

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