Granule proteases of hematopoietic cells, a family of versatile inflammatory mediators - An update on their cleavage specificity, in vivo substrates, and evolution

Biological Chemistry

Volumn 395, Issue 1, 2014, Pages 15-49

  Hellman, Lars ^a   Thorpe, Michael ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

chymase; granzyme; mast cell; phage display; serine protease; tryptase

Indexed keywords

ANGIOTENSIN; CATHELICIDIN; CATHEPSIN G; CHROMOGENIC SUBSTRATE; CHYMASE; COMPLEMENT FACTOR D; CYTOKINE; ELASTASE; ENDOTHELIN 1; FIBRONECTIN; GRANZYME; GRANZYME A; GRANZYME B; GRANZYME H; GRANZYME K; GRANZYME M; LEUKOCYTE ELASTASE; LYSOZYME; MEMBRANE ENZYME; MYELOBLASTIN; PEPSIN A; PHOSPHATIDYLSERINE; PROTEINASE; REACTIVE OXYGEN METABOLITE; RECOMBINANT ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RESTRICTION ENDONUCLEASE; SERINE PROTEINASE; TRYPTASE; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG;

ALLERGIC REACTION; ANTIBACTERIAL ACTIVITY; APOPTOSIS; BASOPHIL; BLOOD PRESSURE REGULATION; CELL GRANULE; CHROMATIN CONDENSATION; CROSS REACTION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; DNA FRAGMENTATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; EVOLUTION; EXTRACELLULAR MATRIX; GENE DUPLICATION; HEMATOPOIETIC CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; MAST CELL; MITOCHONDRIAL RESPIRATION; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; PHAGE DISPLAY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW; SECRETORY GRANULE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TISSUE SPECIFICITY; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANIMALS; CYTOPLASMIC GRANULES; HUMANS; INFLAMMATION MEDIATORS; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; SUBSTRATE SPECIFICITY;

EID: 84890360051     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/hsz-2013-0211     Document Type: Review

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