Human mast cell chymase cleaves pro-IL-18 and generates a novel and biologically active IL-18 fragment

Journal of Immunology

Volumn 177, Issue 12, 2006, Pages 8315-8319

  Omoto, Youichi ^a,c   Tokime, Kazuya ^a,c   Yamanaka, Keiichi ^a,c   Habe, Koji ^a   Morioka, Tatsuhiko ^a   Kurokawa, Ichiro ^a   Tsutsui, Hiroko ^b,c   Yamanishi, Kiyofumi ^b,c   Nakanishi, Kenji ^b,c   Mizutani, Hitoshi ^a,c  

^a MIE UNIVERSITY   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMASE; INTERLEUKIN 18; INTERLEUKIN 1BETA CONVERTING ENZYME; PHENYLALANINE; RECOMBINANT INTERLEUKIN 18; TRYPTASE;

ARTICLE; ATOPIC DERMATITIS; CELL GRANULE; CONNECTIVE TISSUE CELL; CYTOKINE RELEASE; ENZYME ACTIVATION; EXPERIMENTAL MOUSE; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; KERATINOCYTE; MAST CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN TARGETING;

EID: 33845438996     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.12.8315     Document Type: Article

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