Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis

Journal of Cell Biology

Volumn 167, Issue 3, 2004, Pages 457-468

  Pardo, Julián ^a   Bosque, Alberto ^a   Brehm, Reina ^b   Wallich, Reinhard ^c   Naval, Javier ^a   Müllbacher, Arno ^d   Anel, Alberto ^a   Simon, Markus M ^b  

^a UNIVERSITY OF ZARAGOZA   (Spain)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^c UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^d Biology and Environment   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 9; ENDONUCLEASE; ENDONUCLEASE APE 1; GRANZYME A; GRANZYME B; PERFORIN; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; SCAVENGER; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; EX VIVO STUDY; IN VITRO STUDY; KINETICS; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; TARGET CELL DESTRUCTION;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; GRANZYMES; KINETICS; MEMBRANE GLYCOPROTEINS; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; PHOSPHATIDYLSERINES; PORE FORMING CYTOTOXIC PROTEINS; REACTIVE OXYGEN SPECIES; SERINE ENDOPEPTIDASES; T-LYMPHOCYTES, CYTOTOXIC; TIME FACTORS;

ALOCASIA MACRORRHIZOS; ANIMALIA; LETHRINIDAE;

EID: 8444249247     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200406115     Document Type: Article

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