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Volumn 22, Issue 3, 2005, Pages 355-370

Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; GRANZYME A; GRANZYME B; NUCLEOSIDE DIPHOSPHATE KINASE A; PEROXIDE; PROTEIN; PROTEIN APE1; PROTEIN BCL 2; PROTEIN SET; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG;

EID: 15244351845     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2005.02.004     Document Type: Article
Times cited : (308)

References (58)
  • 1
    • 0035831462 scopus 로고    scopus 로고
    • Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition
    • J.B. Alimonti, L. Shi, P.K. Baijal, and A.H. Greenberg Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition J. Biol. Chem. 276 2001 6974 6982
    • (2001) J. Biol. Chem. , vol.276 , pp. 6974-6982
    • Alimonti, J.B.1    Shi, L.2    Baijal, P.K.3    Greenberg, A.H.4
  • 2
    • 0037621465 scopus 로고    scopus 로고
    • Potentiation of Fas-mediated apoptosis by attenuated production of mitochondria-derived reactive oxygen species
    • A. Aronis, J.A. Melendez, O. Golan, S. Shilo, N. Dicter, and O. Tirosh Potentiation of Fas-mediated apoptosis by attenuated production of mitochondria-derived reactive oxygen species Cell Death Differ. 10 2003 335 344
    • (2003) Cell Death Differ. , vol.10 , pp. 335-344
    • Aronis, A.1    Melendez, J.A.2    Golan, O.3    Shilo, S.4    Dicter, N.5    Tirosh, O.6
  • 3
    • 0034107096 scopus 로고    scopus 로고
    • Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid
    • M. Barry, J.A. Heibein, M.J. Pinkoski, S.F. Lee, R.W. Moyer, D.R. Green, and R.C. Bleackley Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid Mol. Cell. Biol. 20 2000 3781 3794
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3781-3794
    • Barry, M.1    Heibein, J.A.2    Pinkoski, M.J.3    Lee, S.F.4    Moyer, R.W.5    Green, D.R.6    Bleackley, R.C.7
  • 4
    • 0030787867 scopus 로고    scopus 로고
    • Recombinant human granzyme a binds to two putative HLA-associated proteins and cleaves one of them
    • P.J. Beresford, C.M. Kam, J.C. Powers, and J. Lieberman Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them Proc. Natl. Acad. Sci. USA 94 1997 9285 9290
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9285-9290
    • Beresford, P.J.1    Kam, C.M.2    Powers, J.C.3    Lieberman, J.4
  • 5
    • 0033137079 scopus 로고    scopus 로고
    • Granzyme a loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation
    • P.J. Beresford, Z. Xia, A.H. Greenberg, and J. Lieberman Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation Immunity 10 1999 585 594
    • (1999) Immunity , vol.10 , pp. 585-594
    • Beresford, P.J.1    Xia, Z.2    Greenberg, A.H.3    Lieberman, J.4
  • 6
    • 0035900714 scopus 로고    scopus 로고
    • Granzyme a activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks
    • P.J. Beresford, D. Zhang, D.Y. Oh, Z. Fan, E.L. Greer, M.L. Russo, M. Jaju, and J. Lieberman Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks J. Biol. Chem. 276 2001 43285 43293
    • (2001) J. Biol. Chem. , vol.276 , pp. 43285-43293
    • Beresford, P.J.1    Zhang, D.2    Oh, D.Y.3    Fan, Z.4    Greer, E.L.5    Russo, M.L.6    Jaju, M.7    Lieberman, J.8
  • 8
    • 0034597057 scopus 로고    scopus 로고
    • Protein ligands to HuR modulate its interaction with target mRNAs in vivo
    • C.M. Brennan, I.E. Gallouzi, and J.A. Steitz Protein ligands to HuR modulate its interaction with target mRNAs in vivo J. Cell Biol. 151 2000 1 14
    • (2000) J. Cell Biol. , vol.151 , pp. 1-14
    • Brennan, C.M.1    Gallouzi, I.E.2    Steitz, J.A.3
  • 9
    • 0026471205 scopus 로고
    • Cell killing and induction of manganous superoxide dismutase by tumor necrosis factor-alpha is mediated by lipoxygenase metabolites of arachidonic acid
    • D.J. Chang, G.M. Ringold, and R.A. Heller Cell killing and induction of manganous superoxide dismutase by tumor necrosis factor-alpha is mediated by lipoxygenase metabolites of arachidonic acid Biochem. Biophys. Res. Commun. 188 1992 538 546
    • (1992) Biochem. Biophys. Res. Commun. , vol.188 , pp. 538-546
    • Chang, D.J.1    Ringold, G.M.2    Heller, R.A.3
  • 10
    • 0026323008 scopus 로고
    • Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: Definition of a family of DNA repair enzymes
    • B. Demple, T. Herman, and D.S. Chen Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes Proc. Natl. Acad. Sci. USA 88 1991 11450 11454
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 11450-11454
    • Demple, B.1    Herman, T.2    Chen, D.S.3
  • 11
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • C. Du, M. Fang, Y. Li, L. Li, and X. Wang Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition Cell 102 2000 33 42
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 12
    • 0036199666 scopus 로고    scopus 로고
    • HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme a
    • Z. Fan, P.J. Beresford, D. Zhang, and J. Lieberman HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A Mol. Cell. Biol. 22 2002 2810 2820
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2810-2820
    • Fan, Z.1    Beresford, P.J.2    Zhang, D.3    Lieberman, J.4
  • 13
    • 0037423932 scopus 로고    scopus 로고
    • Tumor suppressor NM23-H1 is a Granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor
    • Z. Fan, P.J. Beresford, D.Y. Oh, D. Zhang, and J. Lieberman Tumor suppressor NM23-H1 is a Granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor Cell 112 2003 659 672
    • (2003) Cell , vol.112 , pp. 659-672
    • Fan, Z.1    Beresford, P.J.2    Oh, D.Y.3    Zhang, D.4    Lieberman, J.5
  • 15
    • 0033779842 scopus 로고    scopus 로고
    • Induction of human immunodeficiency virus (HIV)-specific CD8 T-cell responses by Listeria monocytogenes and a hyperattenuated Listeria strain engineered to express HIV antigens
    • R.S. Friedman, F.R. Frankel, Z. Xu, and J. Lieberman Induction of human immunodeficiency virus (HIV)-specific CD8 T-cell responses by Listeria monocytogenes and a hyperattenuated Listeria strain engineered to express HIV antigens J. Virol. 74 2000 9987 9993
    • (2000) J. Virol. , vol.74 , pp. 9987-9993
    • Friedman, R.S.1    Frankel, F.R.2    Xu, Z.3    Lieberman, J.4
  • 16
    • 3442886811 scopus 로고    scopus 로고
    • The pathophysiology of mitochondrial cell death
    • D.R. Green, and G. Kroemer The pathophysiology of mitochondrial cell death Science 305 2004 626 629
    • (2004) Science , vol.305 , pp. 626-629
    • Green, D.R.1    Kroemer, G.2
  • 17
    • 0033534446 scopus 로고    scopus 로고
    • Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death
    • A. Gross, X.M. Yin, K. Wang, M.C. Wei, J. Jockel, C. Milliman, H. Erdjument-Bromage, P. Tempst, and S.J. Korsmeyer Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death J. Biol. Chem. 274 1999 1156 1163
    • (1999) J. Biol. Chem. , vol.274 , pp. 1156-1163
    • Gross, A.1    Yin, X.M.2    Wang, K.3    Wei, M.C.4    Jockel, J.5    Milliman, C.6    Erdjument-Bromage, H.7    Tempst, P.8    Korsmeyer, S.J.9
  • 19
    • 0032752882 scopus 로고    scopus 로고
    • Granzyme B-induced loss of mitochondrial inner membrane potential (Delta Psi m) and cytochrome c release are caspase independent
    • J.A. Heibein, M. Barry, B. Motyka, and R.C. Bleackley Granzyme B-induced loss of mitochondrial inner membrane potential (Delta Psi m) and cytochrome c release are caspase independent J. Immunol. 163 1999 4683 4693
    • (1999) J. Immunol. , vol.163 , pp. 4683-4693
    • Heibein, J.A.1    Barry, M.2    Motyka, B.3    Bleackley, R.C.4
  • 21
    • 0028258577 scopus 로고
    • Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
    • J.W. Heusel, R.L. Wesselschmidt, S. Shresta, J.H. Russell, and T.J. Ley Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells Cell 76 1994 977 987
    • (1994) Cell , vol.76 , pp. 977-987
    • Heusel, J.W.1    Wesselschmidt, R.L.2    Shresta, S.3    Russell, J.H.4    Ley, T.J.5
  • 26
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • R.M. Kluck, E. Bossy-Wetzel, D.R. Green, and D.D. Newmeyer The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis Science 275 1997 1132 1136
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 27
    • 0029811838 scopus 로고    scopus 로고
    • Loss of function of cytochrome c in Jurkat cells undergoing Fas-mediated apoptosis
    • A. Krippner, A. Matsuno-Yagi, R.A. Gottlieb, and B.M. Babior Loss of function of cytochrome c in Jurkat cells undergoing Fas-mediated apoptosis J. Biol. Chem. 271 1996 21629 21636
    • (1996) J. Biol. Chem. , vol.271 , pp. 21629-21636
    • Krippner, A.1    Matsuno-Yagi, A.2    Gottlieb, R.A.3    Babior, B.M.4
  • 28
    • 0031918742 scopus 로고    scopus 로고
    • The mitochondrial death/life regulator in apoptosis and necrosis
    • G. Kroemer, B. Dallaporta, and M. Resche-Rigon The mitochondrial death/life regulator in apoptosis and necrosis Annu. Rev. Physiol. 60 1998 619 642
    • (1998) Annu. Rev. Physiol. , vol.60 , pp. 619-642
    • Kroemer, G.1    Dallaporta, B.2    Resche-Rigon, M.3
  • 29
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • H. Li, H. Zhu, C. Xu, and J. Yuan Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis Cell 94 1998 491 501
    • (1998) Cell , vol.94 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.3    Yuan, J.4
  • 30
    • 0141629512 scopus 로고    scopus 로고
    • Nuclear war: The granzyme A-bomb
    • J. Lieberman, and Z. Fan Nuclear war: the granzyme A-bomb Curr. Opin. Immunol. 15 2003 553 559
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 553-559
    • Lieberman, J.1    Fan, Z.2
  • 31
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • X. Luo, I. Budiahardjo, H. Zou, C. Slaughter, and X. Wang Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors Cell 94 1998 481 490
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budiahardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 32
    • 0037059740 scopus 로고    scopus 로고
    • NM23-H1 and NM23-H2 repress transcriptional activities of nuclease-hypersensitive elements in the platelet-derived growth factor-A promoter
    • D. Ma, Z. Xing, B. Liu, N.G. Pedigo, S.G. Zimmer, Z. Bai, E.H. Postel, and D.M. Kaetzel NM23-H1 and NM23-H2 repress transcriptional activities of nuclease-hypersensitive elements in the platelet-derived growth factor-A promoter J. Biol. Chem. 277 2002 1560 1567
    • (2002) J. Biol. Chem. , vol.277 , pp. 1560-1567
    • Ma, D.1    Xing, Z.2    Liu, B.3    Pedigo, N.G.4    Zimmer, S.G.5    Bai, Z.6    Postel, E.H.7    Kaetzel, D.M.8
  • 33
    • 0033521626 scopus 로고    scopus 로고
    • Mitochondria-dependent and -independent regulation of granzyme B-induced apoptosis
    • G. MacDonald, L. Shi, C. Vande Velde, J. Lieberman, and A.H. Greenberg Mitochondria-dependent and -independent regulation of granzyme B-induced apoptosis J. Exp. Med. 189 1999 131 144
    • (1999) J. Exp. Med. , vol.189 , pp. 131-144
    • MacDonald, G.1    Shi, L.2    Vande Velde, C.3    Lieberman, J.4    Greenberg, A.H.5
  • 37
    • 0037459081 scopus 로고    scopus 로고
    • Mitochondria: Releasing power for life and unleashing the machineries of death
    • D.D. Newmeyer, and S. Ferguson-Miller Mitochondria: releasing power for life and unleashing the machineries of death Cell 112 2003 481 490
    • (2003) Cell , vol.112 , pp. 481-490
    • Newmeyer, D.D.1    Ferguson-Miller, S.2
  • 38
    • 0035811511 scopus 로고    scopus 로고
    • Mitochondrial endonuclease G is important for apoptosis in C. elegans
    • J. Parrish, L. Li, K. Klotz, D. Ledwich, X. Wang, and D. Xue Mitochondrial endonuclease G is important for apoptosis in C. elegans Nature 412 2001 90 94
    • (2001) Nature , vol.412 , pp. 90-94
    • Parrish, J.1    Li, L.2    Klotz, K.3    Ledwich, D.4    Wang, X.5    Xue, D.6
  • 40
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • H. Pircher, K. Burki, R. Lang, H. Hengartner, and R.M. Zinkernagel Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen Nature 342 1989 559 561
    • (1989) Nature , vol.342 , pp. 559-561
    • Pircher, H.1    Burki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 41
    • 0028147329 scopus 로고
    • Inhibition of activation-induced death in T cell hybridomas by thiol antioxidants: Oxidative stress as a mediator of apoptosis
    • P.A. Sandstrom, M.D. Mannie, and T.M. Buttke Inhibition of activation-induced death in T cell hybridomas by thiol antioxidants: oxidative stress as a mediator of apoptosis J. Leukoc. Biol. 55 1994 221 226
    • (1994) J. Leukoc. Biol. , vol.55 , pp. 221-226
    • Sandstrom, P.A.1    Mannie, M.D.2    Buttke, T.M.3
  • 42
    • 0035846894 scopus 로고    scopus 로고
    • Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the Set oncoprotein
    • S. Seo, P. McNamara, S. Heo, A. Turner, W.S. Lane, and D. Chakravarti Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the Set oncoprotein Cell 104 2001 119 130
    • (2001) Cell , vol.104 , pp. 119-130
    • Seo, S.1    McNamara, P.2    Heo, S.3    Turner, A.4    Lane, W.S.5    Chakravarti, D.6
  • 43
    • 0026532606 scopus 로고
    • A natural killer cell granule protein that induces DNA fragmentation and apoptosis
    • L. Shi, R.P. Kraut, R. Aebersold, and A.H. Greenberg A natural killer cell granule protein that induces DNA fragmentation and apoptosis J. Exp. Med. 175 1992 553 566
    • (1992) J. Exp. Med. , vol.175 , pp. 553-566
    • Shi, L.1    Kraut, R.P.2    Aebersold, R.3    Greenberg, A.H.4
  • 48
    • 0034694091 scopus 로고    scopus 로고
    • Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation
    • V.R. Sutton, J.E. Davis, M. Cancilla, R.W. Johnstone, A.A. Ruefli, K. Sedelies, K.A. Browne, and J.A. Trapani Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation J. Exp. Med. 192 2000 1403 1414
    • (2000) J. Exp. Med. , vol.192 , pp. 1403-1414
    • Sutton, V.R.1    Davis, J.E.2    Cancilla, M.3    Johnstone, R.W.4    Ruefli, A.A.5    Sedelies, K.6    Browne, K.A.7    Trapani, J.A.8
  • 49
    • 0035910057 scopus 로고    scopus 로고
    • Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK
    • D.A. Thomas, L. Scorrano, G.V. Putcha, S.J. Korsmeyer, and T.J. Ley Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK Proc. Natl. Acad. Sci. USA 98 2001 14985 14990
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14985-14990
    • Thomas, D.A.1    Scorrano, L.2    Putcha, G.V.3    Korsmeyer, S.J.4    Ley, T.J.5
  • 56
    • 0029983059 scopus 로고    scopus 로고
    • Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis
    • N. Zamzami, P. Marchetti, M. Castedo, T. Hirsch, S.A. Susin, B. Masse, and G. Kroemer Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis FEBS Lett. 384 1996 53 57
    • (1996) FEBS Lett. , vol.384 , pp. 53-57
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3    Hirsch, T.4    Susin, S.A.5    Masse, B.6    Kroemer, G.7
  • 57
    • 0035826778 scopus 로고    scopus 로고
    • Granzymes a and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis
    • D. Zhang, P.J. Beresford, A.H. Greenberg, and J. Lieberman Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis Proc. Natl. Acad. Sci. USA 98 2001 5746 5751
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5746-5751
    • Zhang, D.1    Beresford, P.J.2    Greenberg, A.H.3    Lieberman, J.4


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