Human and mouse granzyme M display divergent and species-specific substrate specificities

Biochemical Journal

Volumn 437, Issue 3, 2011, Pages 431-442

  De Poot, Stefanie A H ^a   Westgeest, Marijn ^a   Hostetter, Daniel R ^b   Van Damme, Petra ^c,d   Plasman, Kim ^c,d   Demeyer, Kimberly ^c,d   Broekhuizen, Roel ^a   Gevaert, Kris ^c,d   Craik, Charles S ^b   Bovenschen, Niels ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d GHENT UNIVERSITY   (Belgium)

Author keywords

tubulin; Apoptosis; Degradomics; Granzyme M (GrM); N and C terminal combined fractional diagonal chromatography (COFRADIC); Nucleophosmin (NPM)

Indexed keywords

ALPHA TUBULIN; GRANZYME; GRANZYME M; LEUCINE; METHIONINE; NUCLEOPHOSMIN; PROTEOME; TETRAPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; HYDROLYSIS; MACROMOLECULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEOMICS; SPECIES DIFFERENCE; TUMOR CELL;

AMINO ACID SEQUENCE; ANIMALS; CELL DEATH; CELL LINE; GENE EXPRESSION REGULATION; GENETIC VARIATION; GRANZYMES; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROTEIN CONFORMATION; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; TUBULIN;

EID: 79960208362     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20110210     Document Type: Article

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