Granzyme H induces apoptosis of target tumor cells characterized by DNA fragmentation and Bid-dependent mitochondrial damage

Molecular Immunology

Volumn 45, Issue 4, 2008, Pages 1044-1055

  Hou, Qiang ^a   Zhao, Tongbiao ^a   Zhang, Honglian ^a   Lu, Hongxia ^a   Zhang, Qixiang ^a   Sun, Lei ^a   Fan, Zusen ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

Author keywords

Apoptosis; Bid; Caspase; Granzyme H; Mitochondrial damage

Indexed keywords

CASPASE; CASPASE ACTIVATED DEOXYRIBONUCLEASE; CYTOCHROME C; GRANZYME H; PHOSPHATIDYLSERINE; PROTEIN BID; SERINE PROTEINASE; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; APOPTOSIS; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; CYTOLYSIS; DNA DAMAGE; ENZYME ACTIVATION; FEMALE; HELA CELL; HUMAN; HUMAN CELL; INNATE IMMUNITY; LEUKEMIA CELL LINE; MITOCHONDRIAL TOXICITY; MITOCHONDRION; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; TARGET CELL;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASES; CYTOCHROMES C; DNA FRAGMENTATION; ENZYME ACTIVATION; GRANZYMES; HELA CELLS; HUMANS; JURKAT CELLS; MITOCHONDRIA; PHOSPHATIDYLSERINES; PICHIA; RECOMBINANT PROTEINS;

EID: 35548934666     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.07.032     Document Type: Article

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