Models of hepatotoxicity and the underlying cellular, biochemical and immunological mechanism(s): A critical discussion

Environmental Toxicology and Pharmacology

Volumn 37, Issue 1, 2014, Pages 118-133

  Ingawale, Deepa K ^a   Mandlik, Satish K ^b   Naik, Suresh R ^a  

^a Sinhgad Technical Education Society   (India)

^b SINHGAD COLLEGE OF PHARMACY   (India)

Author keywords

Biochemical and cellular markers; Cytochrome P450; Hepatotoxic agents; Hepatotoxicity risk factors; Models of hepatotoxicity; Oxidative stress

Indexed keywords

AFLATOXIN B1; ALCOHOL; ANTIOXIDANT; ARSENIC; AZATHIOPRINE; BACTERIUM LIPOPOLYSACCHARIDE; BIOLOGICAL MARKER; CADMIUM; CARBON TETRACHLORIDE; CISPLATIN; CYCLOSPORIN A; CYTOKINE; DOXORUBICIN; FAS ANTIGEN; FREE RADICAL; GALACTOSAMINE; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; NONSTEROID ANTIINFLAMMATORY AGENT; OSTEOPONTIN; PARACETAMOL; RIFAMPICIN; STRESS ACTIVATED PROTEIN KINASE; THIOACETAMIDE; TRANSFORMING GROWTH FACTOR BETA; TUBERCULOSTATIC AGENT; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; XENOBIOTIC AGENT;

BILE DUCT LIGATION; BIOCHEMISTRY; CALCIUM HOMEOSTASIS; CELL DAMAGE; DISEASE MODEL; ENDOPLASMIC RETICULUM; EXPERIMENTAL MODEL; GAMMA RADIATION; HUMAN; IMMUNOLOGY; IN VITRO STUDY; LIPID PEROXIDATION; LIVER CELL; LIVER FUNCTION; LIVER INJURY; LIVER PERFUSION; LIVER SLICE; LIVER TOXICITY; LYSOSOME; MITOCHONDRION; MYCOBACTERIUM BOVIS BCG; NONHUMAN; OXIDATIVE STRESS; PREGNANCY; PRIORITY JOURNAL; REVIEW; RISK FACTOR; TOXICITY TESTING;

BIOCHEMICAL AND CELLULAR MARKERS; CYTOCHROME P(450); HEPATOTOXIC AGENTS; HEPATOTOXICITY RISK FACTORS; MODELS OF HEPATOTOXICITY; OXIDATIVE STRESS;

ANIMALS; HUMANS; LIVER DISEASES; MODELS, BIOLOGICAL; RISK FACTORS;

EID: 84890094952     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2013.08.015     Document Type: Review

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