Protective role of taurine against arsenic-induced mitochondria-dependent hepatic apoptosis via the inhibition of PKCδ-JNK pathway

PLoS ONE

Volumn 5, Issue 9, 2010, Pages 1-19

  Das, Joydeep ^a   Ghosh, Jyotirmoy ^a   Manna, Prasenjit ^a   Sil, Parames C ^a  

^a BOSE INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; ARSENIC; BIM PROTEIN; CASPASE 3; CASPASE 9; CATALASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE C DELTA; REACTIVE OXYGEN METABOLITE; ROTTLERIN; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; TAURINE; PROTECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARSENIC POISONING; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME INHIBITION; INCUBATION TIME; LIVER CELL; LIVER PARENCHYMA; LIVER TOXICITY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; CYTOLOGY; DOWN REGULATION; DRUG EFFECT; ENZYMOLOGY; GENETICS; LIVER; METABOLISM; MOUSE; SIGNAL TRANSDUCTION;

RATTUS;

ANIMALS; APOPTOSIS; ARSENIC; DOWN-REGULATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER; MALE; MICE; MITOCHONDRIA; OXIDATIVE STRESS; PROTECTIVE AGENTS; PROTEIN KINASE C-DELTA; RATS; SIGNAL TRANSDUCTION; TAURINE;

EID: 77958609724     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012602     Document Type: Article

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